Development and Application of Tools for the Characterization of the Optogenetics Stimulation of the Cochlea PDF Download
Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download Development and Application of Tools for the Characterization of the Optogenetics Stimulation of the Cochlea PDF full book. Access full book title Development and Application of Tools for the Characterization of the Optogenetics Stimulation of the Cochlea by Carlos Javier Duque Afonso. Download full books in PDF and EPUB format.
Author: Carlos Javier Duque Afonso
Publisher:
ISBN:
Category :
Languages : en
Pages : 0
Get Book Here
Book Description
Five per cent of the world population suffers nowadays from some kind of disabling hearing impairment, and 90% out of them is due to a defective functioning of the first step in the transduction of the soundwave into a neural code: the organ of Corti and the spiral ganglion neurons. The development of the most successful neuroprosthetic device, the cochlear implant, has allowed patients to accomplish fair speech comprehension, but has failed in providing speech comprehension in noisy environments, good frequency discrimination and music and prosody appreciation. The most prominent limitatio...
Author: Carlos Javier Duque Afonso
Publisher:
ISBN:
Category :
Languages : en
Pages : 0
Get Book Here
Book Description
Five per cent of the world population suffers nowadays from some kind of disabling hearing impairment, and 90% out of them is due to a defective functioning of the first step in the transduction of the soundwave into a neural code: the organ of Corti and the spiral ganglion neurons. The development of the most successful neuroprosthetic device, the cochlear implant, has allowed patients to accomplish fair speech comprehension, but has failed in providing speech comprehension in noisy environments, good frequency discrimination and music and prosody appreciation. The most prominent limitatio...
Author: Andrew K. Groves
Publisher: Humana
ISBN: 9781071620212
Category : Medical
Languages : en
Pages : 398
Get Book Here
Book Description
This volume explores the latest techniques in inner ear development, analysis of its sensory cells, and characterization and manipulation of the central auditory and vestibular pathways. The chapters in this book cover topics such as dissection and imaging of the cochlea; behavioral evaluation of animal models of diseases like tinnitus; hair cell function and regeneration; and recent advances in sequencing technology. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Cutting-edge and comprehensive, Developmental, Physiological, and Function Neurobiology of the Inner Ear is a valuable resource for scientists and researchers interested in learning more about this developing field.
Author: W. Herzog
Publisher: John Wiley & Sons
ISBN: 9780471492382
Category : Science
Languages : en
Pages : 586
Get Book Here
Book Description
Dieses Teilgebiet der Biomechanik ist für Sportwissenschaftler und Physiologen von großer Bedeutung! Die umfassende, aktuelle Abhandlung der Skelettmuskelmechanik beschäftigt sich mit drei Themenkreisen: den Mechanismen der Skelettmuskelkontraktion, der Muskelfunktion in vivo und theoretischen Modellen der Muskelfunktion. Auch ein knapper historischer Abriß und ein Ausblick auf noch offene Fragen fehlen nicht. (08/00)
Author: Frank Böhnke
Publisher: S. Karger AG (Switzerland)
ISBN: 9783805569880
Category : Cochlea
Languages : en
Pages : 0
Get Book Here
Book Description
This special issue collects our current knowledge of the mechanical processing of acoustic signals by the cochlea and its containing structures. Many workers in diverse disciplines in otology use the facts from cochlear mechanics for the interpretation of their results. Presented here for the first time is the development of a three-dimensional mechanical model of the curved cochlea including fluid-structure couplings. An important approach for future cochlear modeling is shown by the provision of geometrical data for the input of three-dimensional finite element models by microtomographic imaging. A remarkable article tries to demonstrate a connection between outer hair cell mechanics and the complex phenomenon of tinnitus and will be of special interest for stress engineers. Owing to its strong interdisciplinarity, this issue is not only intended for biophysicists, ENT clinicians and audiologists but also for radiologists, biomechanical engineers and computer engineers.
Author: John R. Smythies
Publisher: Academic Press
ISBN: 012404722X
Category : Medical
Languages : en
Pages : 408
Get Book Here
Book Description
The present day is witnessing an explosion of our understanding of how the brain works at all levels, in which complexity is piled on complexity, and mechanisms of astonishing elegance are being continually discovered. This process is most developed in the major areas of the brain, such as the cortex, thalamus, and striatum. The Claustrum instead focuses on a small, remote, and, until recently, relatively unknown area of the brain. In recent years, researchers have come to believe that the claustrum is concerned with consciousness, a bold hypothesis supported by the claustrum’s two-way connections with nearly every other region of the brain and its seeming involvement with multisensory integrations—the hallmark of consciousness. The claustrum, previously in a humble position at the back of the stage, might in fact be the conductor of the brain’s orchestra. The Claustrum brings together leading experts on the claustrum from the varied disciplines of neuroscience, providing a state-of-the-art presentation of what is currently known about the claustrum, promising lines of current research (including epigenetics), and projections of new lines of investigation on the horizon. Develops a unifying hypothesis about the claustrum’s role in consciousness, as well as the integration of sensory information and other higher brain functions Discusses the involvement of the claustrum with autism, schizophrenia, epilepsy, Alzheimer’s disease, and Parkinson’s disease Coverage of all aspects of the claustrum, from its evolution and development to promising new lines of research, including epigenetics, provides a platform and point of reference for future investigative efforts
Author: Massimo De Vittorio
Publisher:
ISBN:
Category :
Languages : en
Pages : 0
Get Book Here
Book Description
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Author: David Zhou
Publisher: Springer Science & Business Media
ISBN: 0387981209
Category : Technology & Engineering
Languages : en
Pages : 371
Get Book Here
Book Description
Signi?cant progress has been made in the development of neural prostheses for restoration of human functions and improvement of the quality of life. Biomedical engineers and neuroscientists around the world are working to improve the design and performance of existing devices and to develop novel devices for arti?cial vision, arti?cial limbs, and brain-machine interfaces. This book, Implantable Neural Prostheses 2: Techniques and Engineering Approaches, is part two of a two-volume sequence that describes state-of-the-art advances in techniques associated with implantable neural prosthetic devices. The techniques covered include biocompatibility and biostability, hermetic packaging, electrochemical techniques for neural stimulation applications, novel electrode materials and testing, thin-?lm ?exible microelectrode arrays, in situ char- terization of microelectrode arrays, chip-size thin-?lm device encapsulation, microchip-embedded capacitors and microelectronics for recording, stimulation, and wireless telemetry. The design process in the development of medical devices is also discussed. Advances in biomedical engineering, microfabrication technology, and neu- science have led to improved medical-device designs and novel functions. However, many challenges remain. This book focuses on the engineering approaches, R&D advances, and technical challenges of medical implants from an engineering p- spective. We are grateful to leading researchers from academic institutes, national laboratories, as well as design engineers and professionals from the medical device industry who have contributed to the book. Part one of this series covers designs of implantable neural prosthetic devices and their clinical applications.
Author: John K. Niparko
Publisher: Lippincott Williams & Wilkins
ISBN: 9780781777490
Category : Medical
Languages : en
Pages : 372
Get Book Here
Book Description
Thoroughly updated for its Second Edition, this book provides an in-depth discussion on prosthetic restoration of hearing via implantation. The text succinctly discusses the scientific principles behind cochlear implants, examines the latest technology, and offers practical advice on how to assess candidates, how to implant the devices, and what rehabilitation is most effective. The authors thoroughly examine the outcomes of cochlear implantation, the impact on the patient's quality of life, the benefits in relation to the costs, and the implications of cochlear implants for language and speech acquisition and childhood education.
Author: Matt Carter
Publisher: Academic Press
ISBN: 0323915612
Category : Medical
Languages : en
Pages : 416
Get Book Here
Book Description
Modern neuroscience research is inherently multidisciplinary, with a wide variety of cutting edge new techniques to explore multiple levels of investigation. This Third Edition of Guide to Research Techniques in Neuroscience provides a comprehensive overview of classical and cutting edge methods including their utility, limitations, and how data are presented in the literature. This book can be used as an introduction to neuroscience techniques for anyone new to the field or as a reference for any neuroscientist while reading papers or attending talks. Nearly 200 updated full-color illustrations to clearly convey the theory and practice of neuroscience methods Expands on techniques from previous editions and covers many new techniques including in vivo calcium imaging, fiber photometry, RNA-Seq, brain spheroids, CRISPR-Cas9 genome editing, and more Clear, straightforward explanations of each technique for anyone new to the field A broad scope of methods, from noninvasive brain imaging in human subjects, to electrophysiology in animal models, to recombinant DNA technology in test tubes, to transfection of neurons in cell culture Detailed recommendations on where to find protocols and other resources for specific techniques "Walk-through" boxes that guide readers through experiments step-by-step
Author: Kevin J. Mitchell
Publisher: Princeton University Press
ISBN: 0691204152
Category : Psychology
Languages : en
Pages : 305
Get Book Here
Book Description
"What makes you the way you are--and what makes each of us different from everyone else? In Innate, leading neuroscientist and popular science blogger Kevin Mitchell traces human diversity and individual differences to their deepest level: in the wiring of our brains. Deftly guiding us through important new research, including his own groundbreaking work, he explains how variations in the way our brains develop before birth strongly influence our psychology and behavior throughout our lives, shaping our personality, intelligence, sexuality, and even the way we perceive the world. We all share a genetic program for making a human brain, and the program for making a brain like yours is specifically encoded in your DNA. But, as Mitchell explains, the way that program plays out is affected by random processes of development that manifest uniquely in each person, even identical twins. The key insight of Innate is that the combination of these developmental and genetic variations creates innate differences in how our brains are wired--differences that impact all aspects of our psychology--and this insight promises to transform the way we see the interplay of nature and nurture. Innate also explores the genetic and neural underpinnings of disorders such as autism, schizophrenia, and epilepsy, and how our understanding of these conditions is being revolutionized. In addition, the book examines the social and ethical implications of these ideas and of new technologies that may soon offer the means to predict or manipulate human traits. Compelling and original, Innate will change the way you think about why and how we are who we are."--Provided by the publisher.
