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Author: Richard G. Cutler
Publisher: World Scientific
ISBN: 9812775730
Category : Family & Relationships
Languages : en
Pages : 872
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Book Description
This two-volume reference examines the translational research field of oxidative stress and ageing. It focuses on understanding the molecular basis of oxidative stress and its associated age-related diseases, with the goal of developing new methods for treating the human ageing processes.
Author: Richard G. Cutler
Publisher: World Scientific
ISBN: 9812775730
Category : Family & Relationships
Languages : en
Pages : 872
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Book Description
This two-volume reference examines the translational research field of oxidative stress and ageing. It focuses on understanding the molecular basis of oxidative stress and its associated age-related diseases, with the goal of developing new methods for treating the human ageing processes.
Author: R.C. Cutler
Publisher: Birkhäuser
ISBN: 3034873379
Category : Science
Languages : en
Pages : 393
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Book Description
Oxidative stress and aging Over the past several years there has been an extraordinarily rapid growth in our knowledge of free radical chemistry and its possible involvement in both normal essential biology and age related disease and dysfunction. Much of this growth in the traditionally separate sciences of chemistry and molecular gerontology occurred independently, with little interaction or communi cation between the scientists working in these two fields. In view of the growing maturity of the two fields and the potential importance of advancing our knowledge in the area of oxidative stress and aging, we perceived a critical need to organize an international conference the "First Inter national Conference on Oxidative Stress and Aging" in Hawaii in 1994 to bring together the world's leading scientists in the fields of reactive oxygen species and molecular gerontology. The objective of this conference was to provide a unique opportunity for scholars working in these two related and rapidly growing fields to participate in the exchange, integration, and synthesis of new concepts and ideas, to engage in constructive criticism and to initiate new collaborative research projects. The conference focused on the molecular and cellular aspects of aging as related to oxidative stress. It was one of the largest and most comprehensive international conferences held in molecular gerontology. At this conference a call was made for submission of papers to be used in the publication of a book covering the major contributions of the meeting.
Author: David R. Riddle
Publisher: CRC Press
ISBN: 1420005529
Category : Medical
Languages : en
Pages : 413
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Book Description
Recognition that aging is not the accumulation of disease, but rather comprises fundamental biological processes that are amenable to experimental study, is the basis for the recent growth of experimental biogerontology. As increasingly sophisticated studies provide greater understanding of what occurs in the aging brain and how these changes occur
Author: Helmut Sies
Publisher: Academic Press
ISBN: 0128196963
Category : Science
Languages : en
Pages : 878
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Book Description
Oxidative Stress: Eustress and Distress presents current knowledge on oxidative stress within the framework of redox biology and translational medicine. It describes eustress and distress in molecular terms and with novel imaging and chemogenetic approaches in four sections: - A conceptual framework for studying oxidative stress. - Processes and oxidative stress responses. Signaling in major enzyme systems (oxidative eustress), and damaging modification of biomolecules (oxidative distress). - The exposome addresses lifelong exposure and impact on health, nutrient sensing, exercise and environmental pollution. - Health and disease processes, including ischemia-reperfusion injury, developmental and psychological disorders, hepatic encephalopathy, skeletal muscle disorders, pulmonary disease, gut disease, organ fibrosis, and cancer. Oxidative Stress: Eustress and Distress is an informative resource useful for active researchers and students in biochemistry, molecular biology, medicinal chemistry, pharmaceutical science, nutrition, exercise physiology, analytical chemistry, cell biology, pharmacology, clinical medicine, and environmental science. - Characterizes oxidative stress within the framework of redox biology, redox signaling, and medicine - Empowers researchers and students to quantify specific reactants noninvasively, identify redox biomarkers, and advance translational studies - Features contributions from international leaders in oxidative stress and redox biology research
Author: Zsolt Radák
Publisher: Human Kinetics
ISBN: 9780880118811
Category : Health & Fitness
Languages : en
Pages : 286
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Book Description
Explore the emerging field of free radical biology, exercise, and aging with this definitive reference. Free Radicals in Exercise and Agingaddresses the current debate regarding whether free radicals released during exercise accelerate the aging process. It explains how free radicals can serve as important regulators of aerobic processes, and it clarifies the importance of exercise in increasing the efficiency of the antioxidant and oxidative repair systems. Mounting research data indicate that free radicals are involved in a variety of physiological and pathophysiological processes. This book focuses on exercise-induced adaptation. In general, a person's ability to adapt to internal and external changes decreases during the aging process. However, by continually exposing the body to different challenges, regular exercise triggers an adaptation process that keeps the body and mind fit. Free Radicals in Exercise and Agingelucidates the role of free radical species in regulating this process. This text is also one of the first to provide an in-depth review of skeletal muscle oxidative stress and aging. This issue is pivotal because muscle serves such a critical role in mobility and normal life. Free Radicals in Exercise and Aging shares the most current understanding of how reactive oxygen species influence the biology of skeletal muscles. It explores some of the unique characteristics that skeletal muscle displays during aging, both in terms of free radical production and with regard to antioxidant systems. The implications of this research are far-reaching. Mutation of DNA is linked very closely to cancer, and if regular exercise improves the regulation of the antioxidant systems and the oxidative damage repair system, these mechanisms may be a very important tool against this deadly disease. This research-oriented text presents the latest information on the subject. It reviews and critiques current literature and provides critical information for exercise physiologists, sports medicine specialists, sport nutritionists, and gerontologists.
Author: Daniel J. Levitin
Publisher: Penguin
ISBN: 1524744190
Category : Psychology
Languages : en
Pages : 379
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Book Description
INSTANT TOP 10 BESTSELLER • New York Times • USA Today • Washington Post • LA Times “Debunks the idea that aging inevitably brings infirmity and unhappiness and instead offers a trove of practical, evidence-based guidance for living longer and better.”—Daniel H. Pink, author of When and Drive SUCCESSFUL AGING delivers powerful insights: • Debunking the myth that memory always declines with age • Confirming that "health span"—not "life span"—is what matters • Proving that sixty-plus years is a unique and newly recognized developmental stage • Recommending that people look forward to joy, as reminiscing doesn't promote health Levitin looks at the science behind what we all can learn from those who age joyously, as well as how to adapt our culture to take full advantage of older people's wisdom and experience. Throughout his exploration of what aging really means, using research from developmental neuroscience and the psychology of individual differences, Levitin reveals resilience strategies and practical, cognitive enhancing tricks everyone should do as they age. Successful Aging inspires a powerful new approach to how readers think about our final decades, and it will revolutionize the way we plan for old age as individuals, family members, and citizens within a society where the average life expectancy continues to rise.
Author: L. Robert
Publisher: Karger Medical and Scientific Publishers
ISBN: 3318026530
Category : Medical
Languages : en
Pages : 226
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Book Description
Aging inspired a large number of theories trying to rationalize the aging process common to all living beings. In this publication the most important environmental and intrinsic mechanisms involved in the aging process and in its pathological consequences are reviewed. Furthermore theoretical and experimental evidence of the most important theoretical elements based on Darwinian evolution, cellular aging, role of cell membranes, free radicals and oxidative processes, receptor-mediated reactions, the extracellular matrix and immune functions as well as the most important environmental and intrinsic mechanisms involved in the aging process and in its pathological consequences are discussed. These presentations of theories and related experimental facts give a global overview of up to date concepts of the biology of the aging process and are of essential reading not only for specialists in this field but also for practitioners of scientific, medical, social and experimental sciences.
Author: Lawrence H. Lash
Publisher: Elsevier
ISBN: 1483218619
Category : Science
Languages : en
Pages : 527
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Book Description
Methods in Toxicology, Volume 2: Mitochondrial Dysfunction provides a source of methods, techniques, and experimental approaches for studying the role of abnormal mitochondrial function in cell injury. The book discusses the methods for the preparation and basic functional assessment of mitochondria from liver, kidney, muscle, and brain; the methods for assessing mitochondrial dysfunction in vivo and in intact organs; and the structural aspects of mitochondrial dysfunction are addressed. The text also describes chemical detoxification and metabolism as well as specific metabolic reactions that are especially important targets or indicators of damage. The methods for measurement of alterations in fatty acid and phospholipid metabolism and for the analysis and manipulation of oxidative injury and antioxidant systems are also considered. The book further tackles additional methods on mitochondrial energetics and transport processes; approaches for assessing impaired function of mitochondria; and genetic and developmental aspects of mitochondrial disease and toxicology. The text also looks into mitochondrial DNA synthesis, covalent binding to mitochondrial DNA, DNA repair, and mitochondrial dysfunction in the context of developing individuals and cellular differentiation. Microbiologists, toxicologists, biochemists, and molecular pharmacologists will find the book invaluable.
Author: Jose Antonio Morales-Gonzalez
Publisher: BoD – Books on Demand
ISBN: 953511123X
Category : Science
Languages : en
Pages : 516
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Book Description
This work responds to the need to find, in a sole document, the affect of oxidative stress at different levels, as well as treatment with antioxidants to revert and diminish the damage. Oxidative Stress and Chronic Degenerative Diseases - a Role for Antioxidants is written for health professionals by researchers at diverse educative institutions (Mexico, Brazil, USA, Spain, Australia, and Slovenia). I would like to underscore that of the 19 chapters, 14 are by Mexican researchers, which demonstrates the commitment of Mexican institutions to academic life and to the prevention and treatment of chronic degenerative diseases.
Author: Tamas Fulop
Publisher: Springer Science & Business Media
ISBN: 1402090633
Category : Medical
Languages : en
Pages : 1693
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Book Description
This authoritative handbook covers all aspects of immunosenescence, with contributions from experts in the research and clinical areas. It examines methods and models for studying immunosenescence; genetics; mechanisms including receptors and signal transduction; clinical relevance in disease states including infections, autoimmunity, cancer, metabolic syndrome, neurodegenerative diseases, frailty and osteoporosis; and much more.
