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Author: International Agency for Research on Cancer
Publisher: IARC Scientific Publications
ISBN: 9789283221586
Category : Medical
Languages : en
Pages : 0
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Book Description
Mycotoxins are fungal toxins that contaminate many of the most frequently consumed foods and feeds worldwide, including staple foods consumed by many of the poorest and most vulnerable populations in the world. Therefore, human and animal exposure to one or more of this broad group of toxins is widespread. Mycotoxins have the potential to contribute to a diversity of adverse health effects in humans, including cancer, even at low concentrations. Economic burdens resulting from crop contamination are added to those on health. Given the ubiquitous nature of exposure in many countries, an urgent need exists for a coordinated international response to the problem of mycotoxin contamination of food. This book aims to sensitize the international community to the mycotoxin problem in a format that is accessible to a wide audience and is useful to decision-makers across a broad spectrum of disciplines, including agriculture, public health, marketing, and economics. The editors hope that this book will be a stimulus to governments, nongovernmental and international organizations, and the private sector to initiate measures designed to minimize mycotoxin exposure in high-risk populations. The book not only provides a scientific description of the occurrence and effects of mycotoxins but also goes further by outlining approaches to reduce mycotoxin exposure aimed at improving public health in low-income countries.
Author: International Agency for Research on Cancer
Publisher: IARC Scientific Publications
ISBN: 9789283221586
Category : Medical
Languages : en
Pages : 0
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Book Description
Mycotoxins are fungal toxins that contaminate many of the most frequently consumed foods and feeds worldwide, including staple foods consumed by many of the poorest and most vulnerable populations in the world. Therefore, human and animal exposure to one or more of this broad group of toxins is widespread. Mycotoxins have the potential to contribute to a diversity of adverse health effects in humans, including cancer, even at low concentrations. Economic burdens resulting from crop contamination are added to those on health. Given the ubiquitous nature of exposure in many countries, an urgent need exists for a coordinated international response to the problem of mycotoxin contamination of food. This book aims to sensitize the international community to the mycotoxin problem in a format that is accessible to a wide audience and is useful to decision-makers across a broad spectrum of disciplines, including agriculture, public health, marketing, and economics. The editors hope that this book will be a stimulus to governments, nongovernmental and international organizations, and the private sector to initiate measures designed to minimize mycotoxin exposure in high-risk populations. The book not only provides a scientific description of the occurrence and effects of mycotoxins but also goes further by outlining approaches to reduce mycotoxin exposure aimed at improving public health in low-income countries.
Author: Cristina Juan García
Publisher: MDPI
ISBN: 3036514163
Category : Medical
Languages : en
Pages : 156
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Book Description
The evaluation of the presence of mycotoxins in different matrices is achieved through different analytical tools (including quantitative or qualitative determinations). Studies of mycotoxin isolation, using chromatographyc equipment coupled to spectrometry detectors (QTrap-MS/MS, MS/MS tandem, QTOF-MS/MS), are the most useful tools to control their presence. All these studies represent key steps in the establishment of the limits of detection, limits of quantification, points of identification, accuracy, reproducibility, and repeatability of different procedures. The maximum permitted or recommended levels for mycotoxins in different matrices are within a wide range (including the levels tolerated by infants and animals). In addition, decontaminated strategies, as well as control and evaluation of exposure, are demanded by authorities and food safety systems. These authorities are not only concerned with the determination of mycotoxin presence but also with the toxicological effects of mycotoxins, and in vivo or in vitro assays are necessary for a complete evaluation. In fact, these assays are the basis for the control and prevention of population exposure to mycotoxins in dietary exposure studies. The most recent surveys focused on regulated mycotoxins (aflatoxins, fumonisins, trichothecenes, and zearalenones) and emerging toxins, such as enniatins and beauvericin in adult consumers, while very few studies have monitored mycotoxin levels in infant products. This Book of Toxins comprises 11 original contributions and one review. New findings regarding presence of mycotoxins in aromatic and medicinal plants, mango and orange juice, juices, pulps, jams, and beer, from Morocco, Pakistan, and Portugal are reported. In these studies, innovative techniques to study their presence has been developed, including liquid chromatography coupled with time-of-flight mass spectrometry to analyse mycotoxins and conjugated mycotoxins. Novel strategies to detect mycotoxin presence and comparisons the characteristics of a rapid quantitative analysis of different mycotoxins (deoxynivalenol, ochratoxin A, patulin, sterigmatocystin, and zearalenone) are also presented using acetyl- and butyrylcholinesterases and photobacterial strains of luminescent cells. Additionally, toxicological effects of zearalenone metabolites and beauvericin on SH-SY5Y neuronal cells are presented. One important point in the control of mycotoxins is related to decontaminated strategies, and in this sense the efficacy of potentially probiotic fruit-derived Lactobacillus isolates in removing aflatoxin M1 (AFM1) is presented. Other mycotoxin decontaminated techniques included in this book are electron beam irradiation (EBI) and degradation of zearalenone and ochratoxin A using ozone. Finally, a review that summarizes the newly discovered macrocyclic trichothecenes and their bioactivities over the last decade is included.
Author: Christopher P. Wild
Publisher: IARC Working Group Report
ISBN: 9789283225096
Category : Medical
Languages : en
Pages : 0
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Book Description
This book provides an evaluation of measures to reduce exposure to highly toxic and carcinogenic contaminants in staple diets in Africa as well as parts of Asia and Latin America. Many of the poorest people in these regions are exposed to the pervasive natural toxins, aflatoxins and fumonisins, on a daily basis by eating their staple diet of groundnuts, maize, and other cereals. Exposure to mycotoxins at these high levels substantially increases mortality and morbidity. Aflatoxins are a cause of human liver cancer, and fatalities from acute aflatoxin poisoning outbreaks occur in Africa and Asia. The International Agency for Research on Cancer convened a Working Group of world-leading experts to review the health effects of aflatoxins and fumonisins and to evaluate intervention measures. The panel concluded that these mycotoxins not only are a cause of acute poisoning and cancer but also are a likely contributor to the high levels of stunting in children in affected populations. The Working Group also identified effective measures to reduce exposure in developing countries. The panel evaluated 15 interventions, considering the strength of the evidence as well as its completeness and its transferability at an individual, community, or national level. Four of the interventions were judged to be ready for implementation: improvement of dietary diversity; crop sorting; post-harvest measures, including improved storage; and, in Latin America for maize, optimized nixtamalization. These recommendations would be relevant for investment of public, nongovernmental organization, and private funds at the scale of the subsistence farmer, the smallholder, and through to a more advanced value chain.
Author: N Magan
Publisher: Elsevier
ISBN: 1855739089
Category : Technology & Engineering
Languages : en
Pages : 488
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Book Description
Mycotoxins, toxic compounds produced by fungi, pose a significant contamination risk in both animal feed and foods for human consumption. With its distinguished editors and international team of contributors, Mycotoxins in food summarises the wealth of recent research on how to assess the risks from mycotoxins, detect particular mycotoxins and control them at differing stages in the supply chain. Part one addresses risk assessment techniques, sampling methods, modelling and detection techniques used to measure the risk of mycotoxin contamination and the current regulations governing mycotoxin limits in food. Part two looks at how the risk of contamination may be controlled, with chapters on the use of HACCP systems and mycotoxin control at different stages in the supply chain. Two case studies demonstrate how these controls work for particular products. The final section details particular mycotoxins, from ochratoxin A and patulin to zearalenone and fumonisins. Mycotoxins in food is a standard reference for all those concerned with ensuring the safety of food. Discusses the wealth of recent research in this important area Covers risk assessment, detection of particular mycotoxins and how to control them throughout the supply chain Describes how the risk of contamination can be controlled, including the use of HACCP systems
Author: John F. Leslie
Publisher: CABI
ISBN: 1845930827
Category : Science
Languages : en
Pages : 496
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Book Description
This book is an outcome of the MycoGlobe conference in Accra. Most of the chapters are based on invited oral presentations made at the conference. The chapters in this book touch on issues including health, trade, ecology, epidemiology, occurrence, detection, management, awareness and policy. This book serves as a source of information on the occurrence and impact of mycotoxins on everything from trade and health to agricultural production in addition to suggesting opportunities for their management in Africa and elsewhere by researchers, policy makers and development investors.
Author: Mahendra Rai
Publisher: Springer Science & Business Media
ISBN: 3642007252
Category : Science
Languages : en
Pages : 407
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Book Description
Mycotoxins are made by different biosynthetic pathways, and they have an extremely wide range of pharmacological effects. This book will update readers on several cutting-edge aspects of mycotoxin research, including topics such as: new analytical methods for detection; the adoption of an ancient Mexican process for detoxification of aflatoxins; mycotoxin management in Ireland, Lithuania and South America; mycotoxin reduction through plant breeding and integrated management practices; and natural aflatoxin inhibitors from medicinal plants. Further contributions examine ochratoxins, selected trichothecenes, zearalenone, and aflatoxin-like gene clusters, as well as sclerotial development in Aspergillus flavus and A. parasiticus. Of particular interest are the chapters on the potential use of mycotoxins as bioweapons. This book will stimulate new thinking on the need to develop therapeutic as well as preventative interventions to reduce the toxicological threat of mycotoxins.
Author: Palle Krogh
Publisher: Butterworth-Heinemann
ISBN: 9780408705363
Category : Aflatoxins
Languages : en
Pages : 111
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Book Description
Author: Patrick Berka Njobeh
Publisher: BoD – Books on Demand
ISBN: 1838818464
Category : Medical
Languages : en
Pages : 182
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Book Description
This Edited Volume Mycotoxins - Impact and Management Strategies is a collection of reviewed and relevant research chapters, offering a comprehensive overview of recent developments in the field of Mycotoxicology. The book comprises of single chapters authored by various researchers and edited by an expert active in this research area. This book is divided into three sections. Section 1 consists of one chapter that gives an overview of the socioeconomic impact of mycotoxins. Section 2 has five chapters that address the prevention and control of aflatoxins both at pre- and post-harvest stages. Section 3 has two chapters that deal with health impact and control in the poultry industry. This publication aims at providing a thorough overview of the latest research efforts in the field and opens new possible research paths for further novel developments in addressing the problem of mycotoxins.
Author: R. Barkai-Golan
Publisher: Elsevier
ISBN: 0080557856
Category : Science
Languages : en
Pages : 408
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Book Description
Mycotoxins are toxins produced by aerobic, microscopic fungus under special conditions of moisture and temperature. They colonize in a variety of foods from harvest to the grocer. Mycotoxins have gained world wide interest in recent years with the revelation of the effect of these toxins on health. A current example is the presence of ochratoxin A, a human carcinogen and nephrotoxin, in wines. The increased concern about fruit safety has led to increased studies throughout the world and enhanced awareness for stringent regulations governing mycotoxin limits in food. Presented in three defined sections, this is the first book to provide comprehensive analysis of the main mycotoxins contaminating fruits and vegetables and their derived products. The first section provides a safety evaluation of mycotoxins in fruits and vegetables, details regarding factors affecting mycotoxin production and diffusion in the fruit tissue, and recent methods for detection of mycotoxigenic fungi and mycotoxins produced by the fungi. The second part takes a critical look at the main individual mycotoxins and the third section focuses on approaches for prevention and control. * The first book dedicated to mycotoxins in fruits and vegetables * Presents mycological, mycotoxicological and phytopathological aspects of fruits and vegetables * Includes an analysis of detection, prevention and control methods for mycotoxigenic fungi and the mycotoxins they produce * Provides a complete risk assessment and safety evaluation of mycotoxins in perishable produce
Author: John F. Leslie
Publisher: John Wiley & Sons
ISBN: 1118832868
Category : Science
Languages : en
Pages : 376
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Book Description
Cereal grain safety from farm to table Mycotoxin Reduction in Grain Chains examines the ways in which food producers, inspectors, and processors can keep our food supply safe. Providing guidance on identification, eradication, and prevention at each stop on the "grain chain, this book is an invaluable resource for anyone who works with cereal grains. Discussions include breeding and crop management, chemical control, contamination prediction, and more for maize, wheat, sorghum, rice, and other major grains. Relevant and practical in the field, the lab, and on the production floor, this book features critical guidance for every point from farm to table.
