Chemoarchitectonic Atlas of the Developing Mouse Brain PDF Download
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Author: David M. Jacobowitz
Publisher: CRC Press
ISBN: 1466593415
Category : Medical
Languages : en
Pages : 304
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Book Description
Representing the state-of-the-art in neurochemical mapping, Chemoarchitectonic Atlas of the Developing Mouse Brain provides a complete, full-color look at the developing mouse brain. Hundreds of coronal sections are presented, clearly illustrating structures at progressive stages of brain development.
Author: David M. Jacobowitz
Publisher: CRC Press
ISBN: 1466593415
Category : Medical
Languages : en
Pages : 304
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Book Description
Representing the state-of-the-art in neurochemical mapping, Chemoarchitectonic Atlas of the Developing Mouse Brain provides a complete, full-color look at the developing mouse brain. Hundreds of coronal sections are presented, clearly illustrating structures at progressive stages of brain development.
Author: George Paxinos
Publisher: Academic Press
ISBN: 0125476221
Category : Science
Languages : en
Pages : 378
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Book Description
This atlas provides an accurate and detailed depiction of all brain structures at fetal stage E17.5, Day of birth, and Day 6 postnatal. In addition to brain structures, the atlas delineates peripheral nerves, ganglia, arteries, veins, muscles bones and other organs. It is an indispensable guide for the interpretation of nervous system changes in gene knockout and transgenic mice. Contains: 43 photographs and drawings of Nissl-stained coronal sections of the brain of a fetal mouse at E17.5 days, 65 photographs and drawings of Nissl-stained coronal sections of the brain of a mouse on the day of birth, and 73 photographs and drawings of Nissl-stained coronal sections of the brain of a mouse aged 6 days postnatal. The drawings are based on the study of sections stained with Nissl and a range of neuroactive substances. In addition to brain structures, the atlas delineates peripheral nerves, ganglia, arteries, veins, muscles bones and other organs.
Author: George Paxinos
Publisher: Academic Press
ISBN: 0128226463
Category : Science
Languages : en
Pages : 384
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Book Description
Atlas of the Developing Mouse Brain, Second Edition builds on the features of successful first edition, providing a comprehensive and convenient reference for all areas of the mouse brain at Fetal-Day 17.5 (E17.5), Day-of-Birth (P0), and Day-Six postnatal (P6). The book also delineates the parts of the eye, features of the skull, ganglia, nerves, arteries, veins, bones and foramina. This atlas is an essential tool for researchers and students who study the development of the mouse brain, or for those who interpret findings from genetic manipulation. Contains 176 high-resolution color scans of Nissl-stained coronal sections of the brain and skull of the fetal (E17.5), day-of-birth (P0), and day-six postnatal mouse (P6) Includes diagrams that delineate all structures of the brain, as well as peripheral nerves, ganglia, muscles, bones, veins and arteries of the head Presents approximately 5000 corrections and updates from the first edition Includes color codes of the veins, arteries, nerves and ganglions of the skull in diagrams
Author:
Publisher:
ISBN:
Category :
Languages : en
Pages :
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Book Description
Author: George Paxinos
Publisher: Academic Press
ISBN: 9780123742384
Category : Science
Languages : en
Pages : 0
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Book Description
For over two decades, Paxinos and Watson's The Rat Brain in Stereotaxic Coordinates, now in its 6th edition, and Franklin and Paxinos' The Mouse Brain in Stereotaxic Coordinates, now in its 3rd edition, have been the most used neuroanatomy references for neuroscientists. Both the illustrations and nomenclature of the atlas have become standard tools used by almost all research neuroscientists who deal with anatomy, physiology, or function. This new atlas represents the first time an accurate histochemical atlas showing the areas of the mouse brain in microscopic slides in a variety of different stains has been available. Until now researchers studying the mouse brain have been forced to consult the existing histochemical atlases of the rat brain (including Paxinos and Watson's) and extrapolate from rat data - a strategy which is not very accurate and often not successful. This atlas collects systematic images of the mouse brain stained with a range of key chemical markers to complement The Mouse Brain in Stereotaxic Coordinates.
Author: Uta Schambra
Publisher: Springer Science & Business Media
ISBN: 038747093X
Category : Medical
Languages : en
Pages : 552
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Book Description
This is the only book available for studies of the mouse brain before birth. It presents a complete mapping of the developing mouse brain that features imaging of whole brain sections. Users will be able to compare structure shown in the Atlas to what they see in the microscope. This new, greatly expanded edition provides an easily accessible tool for researchers in the fields of normal and abnormal brain development.
Author: Uta B. Schambra
Publisher: Academic Press
ISBN: 1483289087
Category : Science
Languages : en
Pages : 359
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Book Description
The Atlas of the Prenatal Mouse Brain is the latest addition to Academic Press' list of atlases for neuroscientists and neuroscience students. It fills an urgent need for a comprehensive atlas of the developing mouse brain for use in studies of both normal and abnormal development. High-quality photomicrographs of brain sections are depicted in sagittal, coronal, and horizontal planes for four gestational age groups. Each photomicrograph is accompanied by a fully labeled, precision-drawn diagram for easy identification of brain structures. Researchers and students using normal, transgenic, or mutant mouse preparations in developmental neurobiology, neurotoxicology, and biotechnology will welcome this meticulously assembled and accessible guide. Presents 153 photomicrographs of serial brain sections Represents four gestational ages (GD 12 and 14 embryos; GD 16 and 18 fetuses), each depicted in sigittal, coronal, and horizontal planes Includes fully labeled diagrams identifying brain structures for each photomicrograph Provides complete alphabetical lists of brain structures and abbreviations Presents a full description of tissue preparation method Large format, 8-1/2 x 11" pages in a sturdy hardcover case
Author: George Paxinos
Publisher: Academic Press
ISBN: 0128189630
Category : Medical
Languages : en
Pages : 602
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Book Description
The complement to The Rat Brain in Stereotaxic Coordinates, Chemoarchitectonic Atlas of the Rat Brain, Third Edition, features a single brain series of high-quality plates stained with eight different markers, extensively annotated and labelled throughout. Plates from the previous edition of Chemoarchitectonic Atlas of the Rat Brain have been re-scanned at high resolution and are shown in color. Labeled structures have been revised, corrected, and updated, providing users with a streamlined, up-to-date, and highly accurate compendium of chemical markers. Researchers with a need to understand the detailed organization of the rat brain as well as structure/function relationships will need this atlas and its array of stains. Provides an archive of chemical markers in the rat brain used in many areas of research Discusses primary data to help researchers identify structures in their own preparations from neuroanatomical, physiological, neuropharmacological, and gene expression studies Accompanies the gold standard reference on the neuroanatomy of the nervous system of the most important model animal in neuroscience and experimental psychology Covers both the rat forebrain and the rat brainstem Thoroughly revised identification of structures following the new data from The Rat Brain in Stereotaxic Coordinates 7th edition and the Chick Brain in Stereotaxic Coordinates 2nd edition Includes the Expert Consult eBook version, compatible with PC, Mac, and most mobile devices and eReaders, which allows readers to browse, search, and interact with content
Author: Fae Kronman
Publisher:
ISBN:
Category :
Languages : en
Pages : 0
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Book Description
Brain reference atlases have transformed from images of gross anatomy to magnified histological slides to interactive digital 3D models. Today, 3D standard reference brains serve as key resources to understand the spatial organization of the brain and promote interoperability across different studies. Unlike the adult mouse brain, the absence of a standard 3D reference atlas for developing mouse brains has hindered advancement in understanding brain development. Here, we present a multimodal 3D developmental common coordinate framework (DevCCF) spanning mouse embryonic day (E) 11.5, E13.5, E15.5, E18.5, and postnatal day (P) 4, P14, and P56. The DevCCF features undistorted morphologically averaged atlas templates created from magnetic resonance imaging and co-registered high-resolution templates from light sheet fluorescence microscopy. The prosomeric model of mammalian brain development guides 3D anatomical segmentations at each age. To appreciate the developmental gap between P4 and P14, we supplement the DevCCF with the early postnatal developmental atlas (epDevAtlas), featuring morphologically averaged templates created from serial two-photon tomography at ages P4, P6, P8, P10, P12, and P14. Moreover, we integrated the P4 and P14 epDevAtlas and Allen Institute adult mouse brain common coordinate framework (CCFv3) into the undistorted P4, P14, and P56 DevCCF morphology, respectively. The DevCCF and epDevAtlas can be explored via an interactive 3D web visualizer. To demonstrate use cases, we employed the DevCCF to unveil the emergence of GABAergic neurons in embryonic brains and mapped spatial transcriptome cell-type data with the developmental ontology to visualize the gene expression changes through development. Further, we suggest atlas improvements and applications to further progress in basic and translational developmental neuroscience. In summary, this work describes the development of openly accessible 3D standard reference atlases that serve as resources for large-scale data integration to gain a comprehensive understanding of brain development.
Author: John P. Sundberg
Publisher: John Wiley & Sons
ISBN: 1119624576
Category : Medical
Languages : en
Pages : 564
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Book Description
An updated and comprehensive reference to pathology in every organ system in genetically modified mice The newly revised and thoroughly updated Second Edition of Pathology of Genetically Engineered and Other Mutant Mice delivers a comprehensive resource for pathologists and biomedical scientists tasked with identifying and understanding pathologic changes in genetically modified mice. The book is organized by body system, includes descriptions and explanations of a wide range of findings, as well as hundreds of color photographs illustrating both common and rare lesions that may be found in genetically engineered and wild type mice. The book is written by experienced veterinary and medical pathologists working in veterinary medical colleges, medical colleges, and research institutes. Covering the latest discoveries in mouse pathology resulting from advancements in biotechnology research over the last 30 years, this singular and accessible resource is a must-read for veterinary and medical pathologists and researchers working with genetically engineered and other mice. Readers will also benefit from: A thorough introduction to mouse pathology and mouse genetic nomenclature, as well as databases useful for analysis of mutant mice An exploration of concepts related to validating animal models, including the Cinderella Effect Practical discussions of basic necropsy methods and grading lesions for computational analyses Concise diagnostic approaches to the respiratory tract, the oral cavity and GI tract, the cardiovascular system, the liver and pancreas, the skeletal system, and other tissues As a one-stop and up to date reference on mouse pathology, Pathology of Genetically Engineered and Other Mutant Mice is an essential book for veterinary and medical pathologists, as well as for scientists, researchers, and toxicologists whose work brings them into contact with genetically modified mice.
