Bone Marrow Regeneration in Mouse by Using Bone Marrow Derived Stem Cells PDF Download
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Author: Naseem Ahamad
Publisher:
ISBN: 9786268807728
Category :
Languages : en
Pages : 0
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Book Description
A book on Bone Marrow Regeneration in Mouse by using Bone Marrow derived Stem Cells. Bone marrow, a dynamic organ of a mammalian body, carries fundamentally of water, protein, and fat. These ingredients vary from person to person and within the same individual over time. Bone marrow is a delicate, jellied, and powerful tissue which serves as an organ of the immune system. It is restrained in the center and the epiphysis of long bones like femora, tibia, humeri, ribs, pelvis, vertebrae, and skull of the body [2]. Bone marrow holds cellular component and soluble component. The cellular component comprises stem cells such as hematopoietic stem cells (HSCs), mesenchymal stem cells (MSCs), multipotent adult progenitor cells (MAPCs) and stroma cells of bone marrow such as endothelial cells (ECs), osteoclasts, osteoblasts, fibroblasts, tissue macrophages, and adipocytes, and the soluble component constitutes of cytokines, chemokines, growth factors, and hormones [3]. Bone marrow comprises two cellular components, parenchyma or hematopoietic component which includes HSCs and hematopoietic progenitor cells (HPCs) and stoma or vascular component bears non-hematopoietic progenitor cells such as endothelial cells.
Author: Naseem Ahamad
Publisher:
ISBN: 9786268807728
Category :
Languages : en
Pages : 0
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Book Description
A book on Bone Marrow Regeneration in Mouse by using Bone Marrow derived Stem Cells. Bone marrow, a dynamic organ of a mammalian body, carries fundamentally of water, protein, and fat. These ingredients vary from person to person and within the same individual over time. Bone marrow is a delicate, jellied, and powerful tissue which serves as an organ of the immune system. It is restrained in the center and the epiphysis of long bones like femora, tibia, humeri, ribs, pelvis, vertebrae, and skull of the body [2]. Bone marrow holds cellular component and soluble component. The cellular component comprises stem cells such as hematopoietic stem cells (HSCs), mesenchymal stem cells (MSCs), multipotent adult progenitor cells (MAPCs) and stroma cells of bone marrow such as endothelial cells (ECs), osteoclasts, osteoblasts, fibroblasts, tissue macrophages, and adipocytes, and the soluble component constitutes of cytokines, chemokines, growth factors, and hormones [3]. Bone marrow comprises two cellular components, parenchyma or hematopoietic component which includes HSCs and hematopoietic progenitor cells (HPCs) and stoma or vascular component bears non-hematopoietic progenitor cells such as endothelial cells.
Author: David S. Allan
Publisher: Springer Science & Business Media
ISBN: 1617794716
Category : Science
Languages : en
Pages : 217
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Book Description
Blood has long been viewed as a conduit for therapy, stemming from the ancient days of phlebotomy to remove evil humors to the development of successful blood transfusions to replace missing blood components. The identification and characterization of hematopoietic stem cells by Drs. Till and McCulloch revolutionized the field and soon after, non-hematopoietic stem and progenitor cells were characterized from the blood and bone marrow. Some of these cell types and various blood-derived cell lineages are involved in the repair of various types of tissue damage that span the spectrum of medical disorders. The goal of this book is to provide an up-to-date review of the various types of blood-derived cells with regenerative capacity, identify opportunities for intervention by examining specific clinical applications, and recognize the regulatory environment that will encompass future therapies in regenerative medicine.
Author: Nagy A Habib
Publisher: World Scientific
ISBN: 1908979429
Category : Science
Languages : en
Pages : 305
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Book Description
This second book in the Stem Cell Repair and Regeneration series provides a deeper exploration of the therapeutic potential of undifferentiated human stem cells.Regenerative medicine is an extremely fast-moving field which is evolving from the initial days of hype and excitement to a more realistic appraisal of the role of stem cells in the treatment of degenerative disorders. The series aims to keep abreast of these changes by combining new knowledge in stem cell biology and therapeutic applications.The current volume contains papers by the field's leading scientists and explores the current knowledge on cell therapy for different diseases and injured organs, including diabetes, liver and heart disease./a
Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309170427
Category : Science
Languages : en
Pages : 112
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Book Description
Recent scientific breakthroughs, celebrity patient advocates, and conflicting religious beliefs have come together to bring the state of stem cell researchâ€"specifically embryonic stem cell researchâ€"into the political crosshairs. President Bush's watershed policy statement allows federal funding for embryonic stem cell research but only on a limited number of stem cell lines. Millions of Americans could be affected by the continuing political debate among policymakers and the public. Stem Cells and the Future of Regenerative Medicine provides a deeper exploration of the biological, ethical, and funding questions prompted by the therapeutic potential of undifferentiated human cells. In terms accessible to lay readers, the book summarizes what we know about adult and embryonic stem cells and discusses how to go about the transition from mouse studies to research that has therapeutic implications for people. Perhaps most important, Stem Cells and the Future of Regenerative Medicine also provides an overview of the moral and ethical problems that arise from the use of embryonic stem cells. This timely book compares the impact of public and private research funding and discusses approaches to appropriate research oversight. Based on the insights of leading scientists, ethicists, and other authorities, the book offers authoritative recommendations regarding the use of existing stem cell lines versus new lines in research, the important role of the federal government in this field of research, and other fundamental issues.
Author: Nagy A Habib
Publisher: World Scientific
ISBN: 1783260297
Category : Science
Languages : en
Pages : 258
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Book Description
Stem cell research is one of the leading “cutting edge” areas of life science research in the world today and is a topic of significant interest to a broad range of the medical and scientific community. This authoritative book provides reviews by the field's leading scientists and covers many of the areas in which stem cells are becoming increasingly important, such as in organ repair and regeneration. Stem cells offer the possibility of cell therapy issues to treat a myriad of diseases, conditions, and disabilities including Parkinson's and Alzheimer's diseases, spinal cord injury, stroke, heart disease, and diabetes.
Author: Katalin Kauser
Publisher: Springer Science & Business Media
ISBN: 3540689761
Category : Medical
Languages : en
Pages : 293
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Book Description
The ambitious goal of this volume is to provide – in chapters written by accomplished scientists and experts in their field – a comprehensive overview of the currently available information related to the therapeutic utility of adult bone marrow-derived cells. With excitement generated almost daily about the possible uses of stem cells to treat human disease, but the controversy surrounding their use still raging, adult bone-marrow derived cells are more readily available, and have a staggering range of uses.
Author: Natasa Levicar
Publisher: Imperial College Press
ISBN: 1860949819
Category : Medical
Languages : en
Pages : 318
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Book Description
Stem cell research is one of the leading "cutting edge" areas of life science research in the world today and is a topic of significant interest to a broad range of the medical and scientific community. This authoritative book provides reviews by the field's leading scientists and covers many of the areas in which stem cells are becoming increasingly important, such as in organ repair and regeneration. Stem cells offer the possibility of cell therapy issues to treat a myriad of diseases, conditions, and disabilities including Parkinson's and Alzheimer's diseases, spinal cord injury, stroke, heart disease, and diabetes.
Author: Taner Demirer
Publisher: BoD – Books on Demand
ISBN: 9535122274
Category : Science
Languages : en
Pages : 210
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Book Description
This book documents the increased amount of stem cell-related research, basic and clinical applications as well as views for the future. The book covers a wide range of issues related to new developments and innovations in cell-based therapies discussed in basic and clinical chapters from authors around the world involved in stem cell studies and research. It thereby complements and extends the basic coverage of stem cells, such as mesenchymal stem cells, effect of stem cells on aging, cover hematopoietic stem cells, storage and cryopreservation, issues related to clinical applications such as haploidentical transplants and use of stem cells for the treatment of Huntingtons disease. Clearly, the treatment of various malignant and nonmalignant diseases depends heavily on stem cells, and this book is well positioned to provide comprehensive coverage of these developments.
Author: Birgit Weyand
Publisher: Springer
ISBN: 3642379443
Category : Technology & Engineering
Languages : en
Pages : 309
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Book Description
Engineered MSCs from Patient-Specific iPS Cells, by Irina Eberle, Mohsen Moslem, Reinhard Henschler, Tobias Cantz Fate of Intravenously Injected Mesenchymal Stem Cells and Significance for Clinical Application, by Beate Wagner, Reinhard Henschler The Implications of Stem Cell Applications for Diseases of the Respiratory System, by Mei Ling Lim, Philipp Jungebluth, Paolo Macchiarini Potential of Mesenchymal Stem Cell Applications in Plastic and Reconstructive Surgery, by Birgit Weyand, Peter M. Vogt General Principles for the Regeneration of Bone and Cartilage, by Michael Jagodzinski, C. Haasper Adult Mesenchymal Stem Cells Explored in the Dental Field, by K. M. Fawzy El-Sayed, C. Dörfer, F. Fändrich, F. Gieseler, M. H. Moustafa, H. Ungefroren Mesenchymal Stem Cell Therapy and Lung Diseases, by Khondoker M. Akram, Sohel Samad, Monica Spiteri, Nicholas R. Forsyth Mesenchymal Stem Cells as Cellular Immunotherapeutics in Allogeneic Hematopoietic Stem Cell Transplantation, by Claudia Papewalis, Daniela Topolar, Barbara Götz, Stefan Schönberger, Dagmar Dilloo New Cell-Based Therapy Paradigm: Induction of Bone Marrow-Derived Multipotent Mesenchymal Stromal Cells into Pro-Inflammatory MSC1 and Anti-inflammatory MSC2 Phenotypes, by Aline M. Betancourt Interactions Between Mesenchymal Stem Cells and Dendritic Cells, by Grazia Maria Spaggiari, Lorenzo Moretta MSC and Tumors: Homing, Differentiation, and Secretion Influence Therapeutic Potential, by Naomi D’souza, Jorge Sans Burns, Giulia Grisendi, Olivia Candini, Elena Veronesi, Serena Piccinno, Edwin M. Horwitz, Paolo Paolucci, Pierfranco Conte, Massimo Dominici Sources of Mesenchymal Stem Cells: Current and Future Clinical Use, by Michela Pozzobon, Martina Piccoli, Paolo De Coppi Role of the EU Framework in Regulation of Stem Cell-Based Products, by Giovanni Migliaccio, Cristina Pintus
Author: Marc S. Penn
Publisher: Springer Science & Business Media
ISBN: 1597452726
Category : Medical
Languages : en
Pages : 314
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Book Description
Over the past 5 years there has been great excitement and controversy in the scientific, financial, and lay literature for the potential of stem cell-based strategies for the prev- tion and treatment of chronic heart failure (CHF). Not that long ago we believed we were born with a set number of cardiac myocytes and that once damaged there was no hope to replace them. The interest in the field stems from the magnitude of cardiovascular disease in the world. Our ability to treat and help patients survive acute myocardial infarction (MI) has resulted in a near epidemic of CHF. There are more than 5 million Americans who currently carry the diagnosis of CHF. With more than 1 million MIs a year in the United States, there are approx 500,000 new cases of CHF diagnosed each year. The goal of Stem Cells and Myocardial Regeneration is to present, in a coherent manner, the current state of knowledge of stem cell-based therapies for cardiac dysfunction, including current findings in both the laboratory and the clinic trials. The first section of this Stem Cells and Myocardial Regeneration focuses on the magnitude of the problem and the successes and failures of what we consider optimal medical therapy. It is on this background that stem cell-based therapy needs to build.
