Author: N.N. Sukhareva-Buell
Publisher: Springer Science & Business Media
ISBN: 9400710887
Category : Science
Languages : en
Pages : 122
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Book Description
The search for new producers of biologically active substances (BAS) against human and animal diseases continues to be an important task in biology and medicine. Experimental work must be carried out well in advance of need because it takes an average of ten years to develop a new medication, as well as additional time to put it on the market. Study of the Protozoa forms a special branch of biology - protozoology. The traditional fields of protozoology are taxonomy, phylogeny, morphology, cytology, evolution, ecology and host parasite-interactions. The Protozoa is the only taxon among the microscopic organisms, which has not been persistently studied as a source of BAS. This book then is the result of the research on the project: "Biologically active substances of the Mastigophora (Flagellates)". The research was carried out at the Laboratory of Antibiotics, Department of Microbiology, Biological Faculty of Moscow State University. Articles of other authors on the matter have been considered as the important part of this reference book. The goal of the reference book is to elucidate scientific approaches, which lead to obtaining biologically active substances from cultures of protozoa; the book reviews the historical background in connection with contemporary development of the field. N.N. Sukhareva ACKNOWLEDGMENTS The research was performed in fruitful cooperation with my research associates (V. Urinyuk, T. Titiova, L. Udalova, R. Zeleneva, V. Brusovanik, M. Zaretskaya), postgraduate students (N. Kalenik, M. Chuenkova, V. Vasilevskaya, V. Khorokhorina), my colleagues at Moscow State University (Yu. Kozlov and I.
Author: André Lwoff
Publisher:
ISBN:
Category : Biochemistry
Languages : en
Pages : 456
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Book Description
Author: Michael A. Sleigh
Publisher: Elsevier Publishing Company
ISBN:
Category : Science
Languages : en
Pages : 336
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Book Description
Author: Allen I. Laskin
Publisher: CRC-Press
ISBN: 9780849372100
Category : Science
Languages : en
Pages : 608
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Book Description
Basic information on antibiotics and other biologically active prod-ucts are presented in these two easy-to-read volumes. The first volume is devoted entirely to antibiotics and consists of data as-sembled from the Index of Antibiotics from Actinomycetes. High-lighted are antibiotics from bacteria and from phycomycetes and other fungi. Mutasynthetic antibiotics are also discussed. In the second volume, data on biologically active substances is pre-sented. Antiviral compounds, pharmacologically active compounds from microbial sources and plant products not readily considered antibiotics are featured. In addition, compounds produced commer-cially by fermentation and some products of the "new biotechnol-ogy" are listed. PART A: ANTIBIOTICS
Author: Şebnem Hazal Gülşen
Publisher:
ISBN:
Category :
Languages : en
Pages : 0
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Book Description
Natural products have been proven to be important starting points for the development of new drugs. Bacteria in the genera Photorhabdus and Xenorhabdus produce antimicrobial compounds as secondary metabolites to compete with other organisms. Our study is the first comprehensive study screening the anti-protozoal activity of supernatants containing secondary metabolites produced by 5 Photorhabdus and 22 Xenorhabdus species against human parasitic protozoa, Acanthamoeba castellanii, Entamoeba histolytica, Trichomonas vaginalis, Leishmania tropica and Trypanosoma cruzi, and the identification of novel bioactive antiprotozoal compounds using the easyPACId approach (easy Promoter Activated Compound Identification) method. Though not in all species, both bacterial genera produce antiprotozoal compounds effective on human pathogenic protozoa. The promoter exchange mutants revealed that antiprotozoal bioactive compounds produced by Xenorhabdus bacteria were fabclavines, xenocoumacins, xenorhabdins and PAX peptides. Among the bacteria assessed, only P. namnaoensis appears to have acquired amoebicidal property which is effective on E. histolytica trophozoites. These discovered antiprotozoal compounds might serve as starting points for the development of alternative and novel pharmaceutical agents against human parasitic protozoa in the future.
Author: Rajeshwar P. Sinha
Publisher: Academic Press
ISBN: 0128206594
Category : Science
Languages : en
Pages : 502
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Book Description
Natural Bioactive Compounds: Technological Advancements deals with the latest breakthroughs in the field of screening, characterization and novel applications of natural bioactive compounds from diverse group of organisms ranging from bacteria, viruses, cyanobacteria, algae, fungi, bryophytes, higher plants, sponges, corals and fishes. Written by some of the most reputed scientists in the field, this book introduces the reader to strategies and methods in the search for bioactive natural products. It is an essential read for researchers and students interested in bioactive natural products, their biological and pharmacological properties, their possible use as chemopreventive or chemotherapeutic agents, and other future potential applications. Explores natural sources of bioactive compounds, including cyanobacteria, bacteria, viruses, fungi and higher plants Discusses the potential applications of biological products, such as their use in medicine (antibiotics, cancer research, immunology), as food additives, supplements and technological substances Analyzes the contributions of emerging or developing technologies for the study of bioactive natural compounds (characterization and purification)
Author: J. F. Darbyshire
Publisher: Oxford University Press, USA
ISBN:
Category : Science
Languages : en
Pages : 232
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Book Description
Protozoa are active components of the soil microfauna. For example, they may stimulate bacterial metabolism and some fungal metabolites can lyse protozoa. They may be predators of bacteria and hence have a role in biological control. Their presence in groundwaters can be used as an indicator of pollution, while they are also being used to treat sewage in the activated-sludge and reed-bed processes. They are believed to be major secondary decomposers in soil and increased knowledge about these microorganisms is important to sustain soil fertility and food production. This book is the first in English for 65 years devoted entirely to soil protozoology. It is written by experienced microbiologists and should be of interest to protozoologists, other microbiologists, and soil scientists.
Author: Genoveva F. Esteban
Publisher: Springer Nature
ISBN: 3030599795
Category : Science
Languages : en
Pages : 188
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Book Description
This book emphasises the important role that protozoa play in many natural ecosystems. To shed new light on their individual adaptive skills, the respective chapters examine the ecology and functional biology of this diverse group of eukaryotic microbes. Protozoa are well-established model organisms that exemplify many general problems in population ecology and community ecology, as well as evolutionary biology. Their particular characteristics, like large population sizes, life cycles and motile sensory behaviour, have a profound impact on their survival, distribution, and interaction with other species. Thus, readers will also be introduced to protozoan habitats in a broad range of environments. Even though this group of unicellular organisms is highly diverse, the authors focus on shared ecological patterns. Students and scientists working in the areas of eukaryotic microbiology and ecology will appreciate this updated and revised 2nd Edition as a valuable reference guide to the “lifestyles” of protozoa.
Author: Sabino Aurelio Bufo
Publisher: MDPI
ISBN: 3039289276
Category : Science
Languages : en
Pages : 270
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Book Description
Natural products are increasingly attracting attention from both basic and applied science. Plant secondary metabolites, especially alkaloids, are receiving interest from a wide range of researchers due to their biological activity. They are produced to protect plants from diseases and herbivores. Therefore, they reveal a toxic activity that affects organisms at various levels of biological organization. A growing amount of research is proving their antimicrobial, antifungal, insecticidal, and anticancer activities. That makes them applicable in various fields from medicine, to pharmacology, veterinary, and toxicology, to crop protection. This Special Issue of Toxins, “Biological Activities of Alkaloids: From Toxicology to Pharmacology", collects 15 manuscripts describing the ecological, biological, pharmacological, and toxicological effects as well as structural and analytical aspects of plant alkaloids, their mode of action, and possible application in veterinary, medicine, and plant protection. These studies prove the potential for alkaloid application in various areas of science.
Author: Bruce Alberts
Publisher:
ISBN: 9780815332183
Category : Cytology
Languages : en
Pages : 0
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Book Description
