Biological Properties of Lymphokines with Special Reference to the Human Leukocyte Migration Inhibitory Factor (LIF)

Biological Properties of Lymphokines with Special Reference to the Human Leukocyte Migration Inhibitory Factor (LIF) PDF Author: Klaus Bendtzen
Publisher:
ISBN:
Category : Lymphokines
Languages : en
Pages : 48

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Human Lymphokines

Human Lymphokines PDF Author: Amanullah Khan
Publisher: Elsevier
ISBN: 0323142672
Category : Medical
Languages : en
Pages : 756

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Book Description
Human Lymphokines: The Biological Immune Response Modifiers is a collection of papers presented at the Third International Symposium on Human Lymphokines held on October 15-17, 1981 at the Wadley Institutes of Molecular Medicine in Dallas, Texas. Contributors explore the role of human lymphokines in immune responses and their applications in immunotherapy. The focus is on lymphokines that have either entered clinical trials or are nearing clinical evaluation. Some of the activities of possible immediate significance, such as Glia cell stimulating factor and polyclonal B-cell activator, are also described. This volume is organized into six sections encompassing 56 chapters and begins with an overview of assay systems, touching on topics such as the activation of macrophages by interferon to produce plasminogen and macrophage activation by lymphokine factors. The next sections turn to the production, purification, and biological and chemical characterization of lymphokines. The discussion then shifts to the mechanisms of action of lymphokines in vitro and the use of animal models in lymphokine investigations, including lymphokine fractions in a mouse tumor model and enhancement of natural killing activity by different types of interferon. A great deal of emphasis is placed on macrophage migration inhibitory factor, lymphotoxins, gamma interferon, and interleukins. The book concludes with chapters devoted to the immunoregulatory effects of lymphokines and clinical studies.

Current Catalog

Current Catalog PDF Author: National Library of Medicine (U.S.)
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 1174

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First multi-year cumulation covers six years: 1965-70.

National Library of Medicine Current Catalog

National Library of Medicine Current Catalog PDF Author: National Library of Medicine (U.S.)
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 1184

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Volume 4 Immunopathology

Volume 4 Immunopathology PDF Author: Noel Rose
Publisher: Springer Science & Business Media
ISBN: 1461592755
Category : Medical
Languages : en
Pages : 455

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Book Description
This comprehensive treatise on the reticuloendothelial system is a project jointly shared by individual members of the Reticuloendothelial (RE) Society and bio medical scientists in general who are interested in the intricate system of cells and molecular moieties derived from these cells which constitute the RES. It may now be more fashionable in some quarters to consider these cells as part of what is called the mononuclear phagocytic system or the lymphoreticular system. Nevertheless, because of historical developments and current interest in the subject by investigators from many diverse areas, it seems advantageous to present in one comprehensive treatise current information and knowledge con cerning basic aspects of the RES, such as morphology, biochemistry, phylogeny and ontogeny, physiology, and pharmacology as well as clinical areas including immunopathology, cancer, infectious diseases, allergy, and hypersensitivity. It is anticipated that by presenting information concerning these apparently heterogeneous topics under the unifying umbrella of the RES attention will be focused on the similarities as well as interactions among the cell types constitut ing the RES from the viewpoint of various disciplines. The treatise editors and their editorial board, consisting predominantly of the editors of individual vol umes, are extremely grateful for the enthusiastic cooperation and enormous task undertaken by members of the biomedical community in general and especially by members of the American as well as European and Japanese Reticuloendothe lial Societies.

Theses and Other Publications of the University of Copenhagen

Theses and Other Publications of the University of Copenhagen PDF Author: Københavns universitet
Publisher:
ISBN:
Category : Dissertations, Academic
Languages : en
Pages : 18

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Cumulated Index Medicus

Cumulated Index Medicus PDF Author:
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 1340

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Janeway's Immunobiology

Janeway's Immunobiology PDF Author: Kenneth Murphy
Publisher: Garland Science
ISBN: 9780815344575
Category : Medical
Languages : en
Pages :

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Book Description
The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.

Principles of Cancer Biotherapy

Principles of Cancer Biotherapy PDF Author: Robert K. Oldham
Publisher: Springer Science & Business Media
ISBN: 9048122899
Category : Medical
Languages : en
Pages : 743

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Book Description
At the time of the first edition of Principles of Cancer Biotherapy in 1987, this book represented the first comprehensive textbook on biological therapy. In 1991, when the second edition was published, there was still some doubt on the part of many oncologists and cancer researchers as to the therapeutic value of these new approaches. By 2003 and the fourth edition, it was generally agreed that biopharmaceuticals were producing major opportunities for new cancer therapies. Cancer biotherapy has now truly matured into the fourth modality of cancer treatment. This fifth revised edition describes the tremendous progress that has been made in recent years using biologicals in cancer treatment. This book summarizes an evolving science and a rapidly changing medical practice in biotherapy. In this new millennium, it is now possible to envision a much more diversified system of cancer research and treatment that will afford greater opportunities for a patient’s personalized cancer treatment. This was first envisioned in the 1987 initial edition of this textbook and is now a “new” and popular approach to cancer treatment. Some forms of cancer biotherapy use the strategy of tumor stabilization and control through continued biological therapy, akin to the use of insulin in the treatment of diabetes. This textbook illustrates new methods of thinking and new strategies for control of cancer. It is always difficult to move from past dogma to future opportunity, but this fifth edition of Principles of Cancer Biotherapy illustrates why it is so important to the patients for researchers and clinicians to explore and quickly apply these new opportunities in cancer biotherapy.

Lymphokines

Lymphokines PDF Author: Edgar Pick
Publisher: Elsevier
ISBN: 1483266990
Category : Science
Languages : en
Pages : 473

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Book Description
Lymphokines: A Forum for Immunoregulatory Cell Products deals with immunoregulatory cell products that produce lymphokines. Topics covered include the purification and characterization of transfer factor; activation of cytotoxicity and/or suppressor activity in murine macrophages by lymphokines, lipopolysaccharide, and polyinosinic-polycytidylic acid; and the role of clotting processes in the action of lymphokines on macrophages. A comparison of the immune-modulating effects of interferon and interferon inducers is also presented. Comprised of 13 chapters, this volume begins with a discussion on transfer factor and its ability to react specifically with antigens. The clinical uses of transfer factor are considered with special emphasis on its value as a prophylactic agent. The reader is then introduced to the subject of T cell regulation of the immunoglobulin E (IgE) response via potentiating and suppressor lymphokines, together with the possible clinical application of IgE suppressive factors in the treatment of atopic diseases. Subsequent chapters examine the evidence in favor of the existence of T cell-derived polyclonal B cell activator (PBA) playing a role in both normal antibody responses and autoimmune diseases; the role of suppressor T cells and the associated lymphokines in contact sensitivity in mice; and lymphokine action on macrophages. The book also analyzes the genetics of the response of human and mouse cells to interferons. This monograph will be helpful to practitioners and researchers in the fields of microbiology and immunology.