Biocatalysis: Biochemical Fundamentals And Applications PDF Download
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Author: Peter Grunwald
Publisher: World Scientific Publishing Company
ISBN: 1848168217
Category : Science
Languages : en
Pages : 1052
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Book Description
The book covers the fundamentals of the field of biocatalysis that are not treated in such detail (or even not at all) in existing biocatalysis books or biochemistry textbooks. It of course does not substitute existing biochemistry textbooks but will serve a suitable supplement as it discusses biochemical fundamentals in connection with the respective topics.With focus on the interdisciplinary nature of biocatalysis, the book contains many aspects of fundamental organic chemistry and some of inorganic chemistry as well, which should make it interesting not only for biochemistry but also for chemistry students. An important theme being emphasized in the book is that applied biocatalysis is one of the main prerequisites for a sustainable development.The topics covered ranges from basic enzyme chemistry (biosynthesis, structure, properties, interaction forces, kinetics) to a detailed description of catalytic mechanisms. It covers the fundamentals of the different enzyme classes together with their applications in native and in immobilized state or in the form of whole cells in aqueous as well as non-conventional media. Topics such as catalytic antibodies, nucleic acid catalysts, non-ribosomal peptide synthesis, evolutionary methods, and the design of cells are also included.
Author: Peter Grunwald
Publisher: World Scientific Publishing Company
ISBN: 1848168217
Category : Science
Languages : en
Pages : 1052
Get Book Here
Book Description
The book covers the fundamentals of the field of biocatalysis that are not treated in such detail (or even not at all) in existing biocatalysis books or biochemistry textbooks. It of course does not substitute existing biochemistry textbooks but will serve a suitable supplement as it discusses biochemical fundamentals in connection with the respective topics.With focus on the interdisciplinary nature of biocatalysis, the book contains many aspects of fundamental organic chemistry and some of inorganic chemistry as well, which should make it interesting not only for biochemistry but also for chemistry students. An important theme being emphasized in the book is that applied biocatalysis is one of the main prerequisites for a sustainable development.The topics covered ranges from basic enzyme chemistry (biosynthesis, structure, properties, interaction forces, kinetics) to a detailed description of catalytic mechanisms. It covers the fundamentals of the different enzyme classes together with their applications in native and in immobilized state or in the form of whole cells in aqueous as well as non-conventional media. Topics such as catalytic antibodies, nucleic acid catalysts, non-ribosomal peptide synthesis, evolutionary methods, and the design of cells are also included.
Author: Peter Grunwald
Publisher: World Scientific Publishing Company
ISBN: 1783269103
Category : Science
Languages : en
Pages : 1314
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Book Description
In this Completely Revised and Extended Edition with a significantly enhanced content, all Chapters have been updated considering relevant literature and recent developments until 2016 together with application oriented examples with a focus on Industrial Biocatalysis. Newly treated topics comprise among others systems metabolic engineering approaches, metagenome screening, new tools for pathway engineering, and de-novo computational design as actual research areas in biocatalysis. Information about different aspects of RNA technologies, and completely new Chapters on 'Fluorescent Proteins' and 'Biocatalysis and Nanotechnology' are also included.
Author: Andreas S. Bommarius
Publisher: John Wiley & Sons
ISBN: 9783527303441
Category : Science
Languages : en
Pages : 648
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Book Description
Mittlerweile nutzen alle so genannten Life Sciences (z.B. Pharma- und Ernährungswissenschaften) die Möglichkeiten der Biokatalyse. Auch das Interesse der verarbeitenden Industrie an umweltverträglichen Prozessen wächst stetig. Da kommt es nicht von ungefähr, dass die Erforschung von Biokatalysatoren weiter vorangeschritten ist als die anderer Katalysatorentypen. Biocatalysis gibt einen aktuellen Überblick über das Wissen in diesem Gebiet, von den theoretischen Grundlagen bis hin zu Anwendungen und einem Ausblick in die Zukunft. Bommarius und Riebel geht es in ihrem Buch nicht nur um Reaktionen, Produkte und Prozesse im Zusammenhang mit biologischen Katalysen und Katalysatoren. Sie erläutern auch den Prozess der Entwicklung und Verbesserung von Biokatalysatoren. Dabei schenken sie den Bereichen Chemie, Biologie und Biotechnologie die gleiche Aufmerksamkeit, so dass ihr Buch für Praktiker und Studenten aus allen drei Bereichen von Nutzen ist. Biocatalysis gliedert sich in die Abschnitte "Grundlagen und Basis-Tools", "Fortgeschrittene Tools" sowie "Anwendungen". Im ersten Teil gehen die Autoren unter anderem auf die Stellung der Biokatalyse in der Biotechnologie ein, beschreiben Isolierung und Vorbereitung von Mikroorganismen und stellen molekularbiologische Tools für die Biokatalyse vor. Teil II beschreibt zum Beispiel die Enzymherstellung sowie Methoden zur Protein-Untersuchung und beschäftigt sich mit pharmazeutischen Anwendungen der Biokatalyse und der Bioinformatik. Im letzten Abschnitt geht es schließlich um künstliche Enzyme, das Design biokatalytischer Prozesse und um neue Möglichkeiten, die sich durch den Einsatz der Bioinformatik eröffnen.
Author: Daniela Gamenara
Publisher: John Wiley & Sons
ISBN: 1118409329
Category : Science
Languages : en
Pages : 681
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Book Description
Paves the way for new industrial applications using redox biocatalysis Increasingly, researchers rely on the use of enzymes to perform redox processes as they search for novel industrial synthetic routes. In order to support and advance their investigations, this book provides a comprehensive and current overview of the use of redox enzymes and enzyme-mediated oxidative processes, with an emphasis on the role of redox enzymes in chemical transformations. The authors examine the full range of topics in the field, from basic principles to new and emerging research and applications. Moreover, they explore everything from laboratory-scale procedures to industrial manufacturing. Redox Biocatalysis begins with a discussion of the biochemical features of redox enzymes as well as cofactors and cofactor regeneration methods. Next, the authors present a variety of topics and materials to the research and development of full-scale industrial applications, including: Biocatalytic applications of redox enzymes such as dehydrogenases, oxygenases, oxidases, and peroxidases Enzyme-mediated oxidative processes based on biocatalytic promiscuity All the steps from enzyme discovery to robust industrial processes, including directed evolution, high-throughput screening, and medium engineering Case studies tracing the development of industrial applications using biocatalytic redox reactions Each chapter ends with concluding remarks, underscoring the key scientific principles and processes. Extensive references serve as a gateway to the growing body of research in the field. Researchers in both academia and industry will find this book an indispensable reference for redox biotransformations, guiding them from underlying core principles to new discoveries and emerging industrial applications.
Author: Peter Grunwald
Publisher:
ISBN: 9781783269099
Category : Electronic books
Languages : en
Pages : 1314
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Book Description
Author: Peter Grunwald
Publisher: CRC Press
ISBN: 9814463892
Category : Medical
Languages : en
Pages : 1201
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Book Description
Biocatalysis has become an essential tool in the chemical industry and is the core of industrial biotechnology, also known as white biotechnology, making use of biocatalysts in terms of enzymes or whole cells in chemical processes as an alternative to chemical catalysts. This shift can be seen in the many areas of daily life where biocatalysts-with
Author: Se-Kwon Kim
Publisher: CRC Press
ISBN: 1000628973
Category : Medical
Languages : en
Pages : 474
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Book Description
This book provides the latest comprehensive methods for isolation and other novel techniques for marine product development. Furthermore, this book offers knowledge on the biological, medical, and industrial applications of marine-derived medicinal food substances. There has been a tremendous increase in the products derived from marine organisms for commercial application in industries every year. Functional foods of medicinal value are particularly in demand as new technology allows the stabilization of natural ingredients and their availability in pure forms to solve various human diseases. Marine flora and fauna have essential elements and trace minerals that nurture various hormones produced in the endocrine system to regulate the respective metabolisms, thereby providing a safe and healthy life to humans. The overall presentation and clear demarcation of the contents by worldwide contributions is a novel entry point into the market of medicinal foods from the sea. The exploration of marine habitats for novel materials are discussed throughout the book. The exploration and exploitation of the biochemistry of sea flora and fauna are limited, and this book extends the research possibilities into numerous marine habitats. Various approaches for extracting and applying the flora and fauna are discussed. This book will be of value to researchers, marine biotechnologists, and medical practitioners, due to the vast information, as well as industrial and medical applications of marine substances all in one place.
Author: Kurt Faber
Publisher: Springer
ISBN: 3319615904
Category : Science
Languages : en
Pages : 442
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Book Description
This well-established textbook on biocatalysis provides a basis for undergraduate and graduate courses in modern organic chemistry, as well as a condensed introduction into this field. After a basic introduction into the use of biocatalysts—principles of stereoselective transformations, enzyme properties and kinetics—the different types of reactions are explained according to the 'reaction principle', such as hydrolysis, reduction, oxidation, C–C bond formation, etc. Special techniques, such as the use of enzymes in organic solvents, immobilization techniques, artificial enzymes and the design of cascade-reactions are treated in a separate section. A final chapter deals with the basic rules for the safe and practical handling of biocatalysts. The use of biocatalysts, employed either as isolated enzymes or whole microbial cells, offers a remarkable arsenal of highly selective transformations for state-of-the-art synthetic organic chemistry. Over the last two decades, this methodology has become an indispensable tool for asymmetric synthesis, not only at the academic level, but also on an industrial scale. In this 7th edition new topics have been introduced which include alcohol and amine oxidases, amine dehydrogenases, imine reductases, haloalkane dehalogenases, ATP-independent phosphorylation, Michael-additions and cascade reactions. This new edition also emphasizes the use of enzymes in industrial biotransformations with practical examples.
Author: Martine Poux
Publisher: CRC Press
ISBN: 1482208180
Category : Science
Languages : en
Pages : 470
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Book Description
This book has been edited by Martine Poux, Patrick Cognet and Christophe Gourdon from the Laboratoire de Genie Chimique/ENSIACET, Toulouse. It presents an ensemble of methods and new chemical engineering routes that can be integrated in industrial processing for safer, more flexible, economical, and ecological production processes in the context of
Author: Peter Grunwald
Publisher: CRC Press
ISBN: 1351767542
Category : Medical
Languages : en
Pages : 1031
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Book Description
Nanobiocatalysis has rapidly developed into a subarea of enzyme biotechnology. It combines the advances in nanotechnology that have generated nanoscale materials of different sizes, shapes, and physicochemical properties, and the excellent characteristics of biocatalysts into an innovative technology. This book provides an overview of the various relations between nanotechnology and biocatalysis. It discusses the fabrication and application of nanomaterials for the immobilization of enzymes used in the sustainable production of goods and chemicals. Nanosupports have several advantages compared with bulk solid materials because of their high surface area, which results in a significantly reduced mass transfer limitation and comparatively high enzyme loading. These characteristics are also of great use for applications in the fields of enzymatic biosensors, biofuel cells, bioelectronics, and photoelectrochemical analyte detection, where conductive nanomaterials improve the rate of electron transfer. The book also presents an overview of nanotoxicology and covers nanostructured enzyme catalysis in organic solvents and its potential application for biodiesel production, probing of enzymatic activity, and identification of enzyme functions of inorganic nanoparticles as enzyme mimics.
