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Author: Peter K Vogt
Publisher:
ISBN: 9783642804526
Category :
Languages : en
Pages : 188
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Book Description
Author: Peter K Vogt
Publisher:
ISBN: 9783642804526
Category :
Languages : en
Pages : 188
Get Book Here
Book Description
Author: Peter K. Vogt
Publisher: Springer Science & Business Media
ISBN: 3642804519
Category : Medical
Languages : en
Pages : 176
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Book Description
When it comes to bacterial disease, we are living in a state of false security. Antibiotics have indeed brought unprecedented health benefits, protection from and cure of bacterial diseases during the past 50 years. But there are ominous signs that the fortress and the defenses built on antibiotics are crumbling. They are crum bling because we wittingly or unwittingly created selective con ditions for the emergence of superior pathogens that can no longer be controlled by antibiotics. There are numerous warnings. After a long period of eclipse tuberculosis has now emerged as a serious threat unchecked by antibiotic treatment. Recent years have seen reports of cholera epidemics, of anthrax infections, of serious problems with Salmonella and even with E. coli, just to name a few. Mankind is in a race with microbial invaders. The challenge is to anticipate and respond to developments that affect the precarious balance between man and microbe. This will re quire new knowledge and it will take time for an effective appli cation of that knowledge.
Author: P.A. Jones
Publisher: Springer
ISBN:
Category : Biography & Autobiography
Languages : en
Pages : 192
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Book Description
This book is a comprehensive survey of new and exciting developments regarding the role of DNA methylation in human cancer. Issues related to the mutagenicity of 5-methylcytosine and the increase in the interaction of chemical and physical carcinogens with these residues is discussed. The book summarizes the modulation of viral gene expression and the silencing of tumor suppressor genes and illustrates mechanisms by which the methylation signal is translated into altered chromatin structure. The relationship between DNA methylation and genomic imprinting and cancer, and changes in CpG island methylation which occur in aging are discussed. Mouse model systems have played a key role in our dissection of the relationship between methylation and cancer, and these are also portrayed together with descriptions of new clinical trials in which methylation inhibitors are being used to treat leukemia, myeloid dysplastic syndromes and hemoglobinopathies.
Author: Alice Prince
Publisher:
ISBN:
Category :
Languages : en
Pages : 77
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Book Description
Author: Alberto Ciferri
Publisher: John Wiley & Sons
ISBN: 1118165845
Category : Science
Languages : en
Pages : 723
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Book Description
This book is a comprehensive study of the subject of ionic interactions in macromolecules. The first parts of the book review and analyze the conventional treatments of fixed charges (e.g. in polyelectrolytes and polyampholytes), including screening and condensation by mobile ions. The interaction of ions with less polar sites on the macromolecule (e.g. amide bonds), and the origin of the lyotropic effects (focusing on binding versus condensation) will also be extensively addressed. The book also explores complex micellar organizations involving charged macromolecules (e.g. DNA) and low-molecular-weight ampholytes and strong protein associations. The resulting structures are relevant to a variety of functional biological systems and synthetic analogs. The contribution of electrostatic and hydrophobic interaction to the stability of proteins and other supramolecular structures will also be analyzed. There are chapters on applications such as deionization and cosmetic formulation. This 21-chapter book is divided into three sections: Fundamentals Mixed Interactions Functions and Applications
Author: Isaura Simões
Publisher: Frontiers Media SA
ISBN: 2889767531
Category : Science
Languages : en
Pages : 113
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Book Description
Author: Gottfried Unden
Publisher: John Wiley & Sons
ISBN: 3527682414
Category : Science
Languages : en
Pages : 240
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Book Description
In light of the rapidity increasing incidence rate of bacterial and fungal infections with multi-resistant pathogens, the metabolic changes associated with host-pathogen interactions offer one of the most promising starting points for developing novel antibiotics. . Part one of this comprehensive guide describes the metabolic adaptation of pathogenic microbes in humans, while part two points to routes for the development of novel antibiotics. This is volume six of the book series on drug discovery in infectious diseases by Paul Selzer.
Author: Kenzo Takada
Publisher: Springer Science & Business Media
ISBN: 9783540415060
Category : Carcinogenesis
Languages : en
Pages : 306
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Book Description
Most people carry EBV in memory B-cells in a latent stage. Many malignancies such as T/NK cell lymphoma, AIDS-associated B-cell lymphoma, gastric carcinoma and Hodgkin's disease have been causally linked to EBV. The development of molecular biology technique has allowed the study of the roles of individual EBV genes that act in the maintenance and disruption of EBV latency.
Author: Kevin L. Williams
Publisher: CRC Press
ISBN: 1420020595
Category : Medical
Languages : en
Pages : 441
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Book Description
This source expertly examines the discovery, biological structure, control, and continued clarification of endotoxin from a parenteral manufacturing perspective, with in-depth discussion of state-of-the-art technologies involving Limulus amebocyte lysate (LAL) such as assay development, automation, depyrogenation. Completely revised and exp
Author:
Publisher:
ISBN:
Category : Communicable diseases
Languages : en
Pages : 936
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Book Description
