Author: Shay Kels
Publisher:
ISBN:
Category :
Languages : en
Pages : 100

Get Book Here

Book Description

Author: John J. Kasianowicz
Publisher: Springer Science & Business Media
ISBN: 9781402006975
Category : Science
Languages : en
Pages : 46

Get Book Here

Book Description
Polymers are essential to biology because they can have enough stable degrees of freedom to store the molecular code of heredity and to express the sequences needed to manufacture new molecules. Through these they perform or control virtually every function in life. Although some biopolymers are created and spend their entire career in the relatively large free space inside cells or organelles, many biopolymers must migrate through a narrow passageway to get to their targeted destination. This suggests the questions: How does confining a polymer affect its behavior and function? What does that tell us about the interactions between the monomers that comprise the polymer and the molecules that confine it? Can we design and build devices that mimic the functions of these nanoscale systems? The NATO Advanced Research Workshop brought together for four days in Bikal, Hungary over forty experts in experimental and theoretical biophysics, molecular biology, biophysical chemistry, and biochemistry interested in these questions. Their papers collected in this book provide insight on biological processes involving confinement and form a basis for new biotechnological applications using polymers. In his paper Edmund DiMarzio asks: What is so special about polymers? Why are polymers so prevalent in living things? The chemist says the reason is that a protein made of N amino acids can have any of 20 different kinds at each position along the chain, resulting in 20 N different polymers, and that the complexity of life lies in this variety.

Author: Michael D. Gordin
Publisher: University of Chicago Press
ISBN: 022600032X
Category : History
Languages : en
Pages : 424

Get Book Here

Book Description
English is the language of science today. No matter which languages you know, if you want your work seen, studied, and cited, you need to publish in English. But that hasn’t always been the case. Though there was a time when Latin dominated the field, for centuries science has been a polyglot enterprise, conducted in a number of languages whose importance waxed and waned over time—until the rise of English in the twentieth century. So how did we get from there to here? How did French, German, Latin, Russian, and even Esperanto give way to English? And what can we reconstruct of the experience of doing science in the polyglot past? With Scientific Babel, Michael D. Gordin resurrects that lost world, in part through an ingenious mechanism: the pages of his highly readable narrative account teem with footnotes—not offering background information, but presenting quoted material in its original language. The result is stunning: as we read about the rise and fall of languages, driven by politics, war, economics, and institutions, we actually see it happen in the ever-changing web of multilingual examples. The history of science, and of English as its dominant language, comes to life, and brings with it a new understanding not only of the frictions generated by a scientific community that spoke in many often mutually unintelligible voices, but also of the possibilities of the polyglot, and the losses that the dominance of English entails. Few historians of science write as well as Gordin, and Scientific Babel reveals his incredible command of the literature, language, and intellectual essence of science past and present. No reader who takes this linguistic journey with him will be disappointed.

Author:
Publisher: Academic Press
ISBN: 0128130709
Category : Medical
Languages : en
Pages : 692

Get Book Here

Book Description
Platform Technologies in Drug Discovery and Validation, Volume 50, the latest release in the Annual Reports in Medicinal Chemistry series, provides timely and critical reviews of important topics in medicinal chemistry, with an emphasis on emerging topics in the biological sciences. Topics covered in this new volume include DELT, Oligos: ASO, siRNA, CRISPR, Micro-fluidic chemistry, High throughput screening, Kinase-centric computational drug development, Virtual Screening, Phenotypic screening, PROTACS, Chemical Biology, Fragment-based lead generation, Antibody-Drug Conjugates, Antibody-recruiting small molecules, Deuteration, and Peptides. Unique for its treatment of platform technologies for medicinal chemistry and target validation Provides a single, rich volume that summaries a broad spectrum of expertise relevant to the field Presents state-of-the-art summaries of platform technologies

Author: Catherine Sheldrick Ross
Publisher: Kids Can Press Ltd
ISBN: 1771381248
Category : Juvenile Nonfiction
Languages : en
Pages : 196

Get Book Here

Book Description
The three most basic shapes -- squares, triangles and circles -- are all around us, from the natural world to the one we've engineered. Full of fascinating facts about these shapes and their 3D counterparts, Shapes in Math, Science and Nature introduces young readers to the basics of geometry and reveals its applications at home, school and everywhere in between. Puzzles and activities add to the fun factor.

Author: National Research Council
Publisher: National Academies Press
ISBN: 0309042283
Category : Mathematics
Languages : en
Pages : 148

Get Book Here

Book Description
As requested by the National Science Foundation (NSF) and the Interagency Committee for Extramural Mathematics Programs (ICEMAP), this report updates the 1984 Report known as the "David Report." Specifically, the charge directed the committee to (1) update that report, describing the infrastructure and support for U.S. mathematical sciences research; (2) assess trends and progress over the intervening five years against the recommendations of the 1984 Report; (3) briefly assess the field scientifically and identify significant opportunities for research, including cross-disciplinary collaboration; and (4) make appropriate recommendations designed to ensure that U.S. mathematical sciences research will meet national needs in coming years. Of the several components of the mathematical sciences community requiring action, its wellspring--university research departments--is the primary focus of this report. The progress and promise of research--described in the 1984 Report relative to theoretical development, new applications, and the refining and deepening of old applications--have if anything increased since 1984, making mathematics research ever more valuable to other sciences and technology. Although some progress has been made since 1984 in the support for mathematical sciences research, the goals set in the 1984 Report have not been achieved. Practically all of the increase in funding has gone into building the infractructure, which had deteriorated badly by 1984. While graduate and postdoctoral research, computer facilities, and new institutes have benefited from increased resources, some of these areas are still undersupported by the standards of other sciences. And in the area of research support for individual investigators, almost no progress has been made. A critical storage of qualified mathematical sciences researchers still looms, held at bay for the moment by a large influx of foreign researchers, an uncertain solution in the longer term. While government has responded substantially to the 1984 Report's recommendations, particularly in the support of infrastructure, the universities generally have not, so that the academic foundations of the mathematical sciences research enterprise are as shaky now as in 1984. The greatet progress has been made in the mathematics sciences community, whose members have shown a growing awareness of the problems confronting their discipline and increased interest in dealing with the problems, particularly in regard to communication with the public and government agencies and involvement in education. (AA)

Author: Jean-Luc Brylinski
Publisher: Springer Science & Business Media
ISBN: 1461202612
Category : Mathematics
Languages : en
Pages : 629

Get Book Here

Book Description
This volume, dedicated to Bertram Kostant on the occasion of his 65th birthday, is a collection of 22 invited papers by leading mathematicians working in Lie theory, geometry, algebra, and mathematical physics. Kostant’s fundamental work in all these areas has provided deep new insights and connections, and has created new fields of research. The papers gathered here present original research articles as well as expository papers, broadly reflecting the range of Kostant’s work.

Author: Andrey V. Korotayev
Publisher: Springer Nature
ISBN: 3030337308
Category : History
Languages : en
Pages : 619

Get Book Here

Book Description
This book introduces a 'Big History' perspective to understand the acceleration of social, technological and economic trends towards a near-term singularity, marking a radical turning point in the evolution of our planet. It traces the emergence of accelerating innovation rates through global history and highlights major historical transformations throughout the evolution of life, humans, and civilization. The authors pursue an interdisciplinary approach, also drawing on concepts from physics and evolutionary biology, to offer potential models of the underlying mechanisms driving this acceleration, along with potential clues on how it might progress. The contributions gathered here are divided into five parts, the first of which studies historical mega-trends in relation to a variety of aspects including technology, population, energy, and information. The second part is dedicated to a variety of models that can help understand the potential mechanisms, and support extrapolation. In turn, the third part explores various potential future scenarios, along with the paths and decisions that are required. The fourth part presents philosophical perspectives on the potential deeper meaning and implications of the trend towards singularity, while the fifth and last part discusses the implications of the Search for Extraterrestrial Intelligence (SETI). Given its scope, the book will appeal to scholars from various disciplines interested in historical trends, technological change and evolutionary processes.

Author: Wil M.P. van der Aalst
Publisher: Springer
ISBN: 9783319730127
Category : Computers
Languages : en
Pages : 0

Get Book Here

Book Description
This book constitutes the proceedings of the 6th International Conference on Analysis of Images, Social Networks and Texts, AIST 2017, held in Moscow, Russia, in July 2017. The 29 full papers and 8 short papers were carefully reviewed and selected from 127 submissions. The papers are organized in topical sections on natural language processing; general topics of data analysis; analysis of images and video; optimization problems on graphs and network structures; analysis of dynamic behavior through event data; social network analysis.

Author: Nikola Kasabov
Publisher: Physica
ISBN: 3790818569
Category : Computers
Languages : en
Pages : 411

Get Book Here

Book Description
This edited volume comprises invited chapters that cover five areas of the current and the future development of intelligent systems and information sciences. Half of the chapters were presented as invited talks at the Workshop "Future Directions for Intelligent Systems and Information Sciences" held in Dunedin, New Zealand, 22-23 November 1999 after the International Conference on Neuro-Information Processing (lCONIPI ANZIISI ANNES '99) held in Perth, Australia. In order to make this volume useful for researchers and academics in the broad area of information sciences I invited prominent researchers to submit materials and present their view about future paradigms, future trends and directions. Part I contains chapters on adaptive, evolving, learning systems. These are systems that learn in a life-long, on-line mode and in a changing environment. The first chapter, written by the editor, presents briefly the paradigm of Evolving Connectionist Systems (ECOS) and some of their applications. The chapter by Sung-Bae Cho presents the paradigms of artificial life and evolutionary programming in the context of several applications (mobile robots, adaptive agents of the WWW). The following three chapters written by R.Duro, J.Santos and J.A.Becerra (chapter 3), GCoghill . (chapter 4), Y.Maeda (chapter 5) introduce new techniques for building adaptive, learning robots.