Ancient and Archaic Genomes

Ancient and Archaic Genomes PDF Author: David Caramelli
Publisher: Mdpi AG
ISBN: 9783036525471
Category : Science
Languages : en
Pages : 116

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Book Description
The development of high-throughput sequencing has triggered a revolution in the study of ancient DNA. In the last decade, methodological advances have allowed researchers to overcome some of the limits linked to the degradation and preservation of nucleic acids, improving the capacity of recovery and analysis of the ancient molecules. This fact, along with a wider accessibility to the next-generation sequencing platforms, has contributed to increase the number of genomic studies on ancient remains. This Special Issue, titled "Ancient and Archaic Genomes", collects original research articles that present different methods and aspects of the paleogenetic research applied to anthropological, archaeological, and historic questions. Interestingly, specific regional contexts and cultural aspects previously poorly studied from a genetic point of view are here investigated. This Special Issue, presenting different methodological approaches and applications, will be a useful resource for both students and young researchers who are interested in ancient DNA studies.

Who We Are and How We Got Here

Who We Are and How We Got Here PDF Author: David Reich
Publisher: Oxford University Press
ISBN: 0192554387
Category : Science
Languages : en
Pages : 320

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Book Description
The past few years have witnessed a revolution in our ability to obtain DNA from ancient humans. This important new data has added to our knowledge from archaeology and anthropology, helped resolve long-existing controversies, challenged long-held views, and thrown up remarkable surprises. The emerging picture is one of many waves of ancient human migrations, so that all populations living today are mixes of ancient ones, and often carry a genetic component from archaic humans. David Reich, whose team has been at the forefront of these discoveries, explains what genetics is telling us about ourselves and our complex and often surprising ancestry. Gone are old ideas of any kind of racial âpurity.' Instead, we are finding a rich variety of mixtures. Reich describes the cutting-edge findings from the past few years, and also considers the sensitivities involved in tracing ancestry, with science sometimes jostling with politics and tradition. He brings an important wider message: that we should recognize that every one of us is the result of a long history of migration and intermixing of ancient peoples, which we carry as ghosts in our DNA. What will we discover next?

Neanderthal Man

Neanderthal Man PDF Author: Svante PŠŠbo
Publisher: Basic Books (AZ)
ISBN: 0465020836
Category : Science
Languages : en
Pages : 290

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Book Description
An influential geneticist traces his investigation into the genes of humanity's closest evolutionary relatives, explaining what his sequencing of the Neanderthal genome has revealed about their extinction and the origins of modern humans.

Who We Are and How We Got Here

Who We Are and How We Got Here PDF Author: David Reich
Publisher: Vintage
ISBN: 1101873469
Category : Science
Languages : en
Pages : 370

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Book Description
A groundbreaking book about how ancient DNA has profoundly changed our understanding of human history. Geneticists like David Reich have made astounding advances in the field of genomics, which is proving to be as important as archeology, linguistics, and written records as a means to understand our ancestry. In Who We Are and How We Got Here, Reich allows readers to discover how the human genome provides not only all the information a human embryo needs to develop but also the hidden story of our species. Reich delves into how the genomic revolution is transforming our understanding of modern humans and how DNA studies reveal deep inequalities among different populations, between the sexes, and among individuals. Provocatively, Reich’s book suggests that there might very well be biological differences among human populations but that these differences are unlikely to conform to common stereotypes. Drawing upon revolutionary findings and unparalleled scientific studies, Who We Are and How We Got Here is a captivating glimpse into humankind—where we came from and what that says about our lives today.

Who We are and how We Got Here

Who We are and how We Got Here PDF Author: David Reich (Of Harvard Medical School)
Publisher: Oxford University Press
ISBN: 0198821255
Category : History
Languages : en
Pages : 368

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Book Description
David Reich describes how the revolution in the ability to sequence ancient DNA has changed our understanding of the deep human past. This book tells the emerging story of our often surprising ancestry - the extraordinary ancient migrations and mixtures of populations that have made us who we are.

Ancestors in Our Genome

Ancestors in Our Genome PDF Author: Eugene E. Harris (Professor)
Publisher: Oxford University Press, USA
ISBN: 0199978034
Category : Science
Languages : en
Pages : 249

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Book Description
Geneticist Eugene Harris presents us with the complete and up-to-date account of the evolution of the human genome.

A Short History of Humanity

A Short History of Humanity PDF Author: Johannes Krause
Publisher: Random House
ISBN: 0753554976
Category : History
Languages : en
Pages : 288

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Book Description
Humanity has often found itself on the precipice. We've survived and thrived because we've never stopped moving... 'Stops you dead in your tracks ... An absolute revelation' Sue Black, bestselling author of All That Remains In this eye-opening book, Johannes Krause, Chair of the Max Planck Institute for the History of Humanity, offers a new way of understanding our past, present and future. Marshalling unique insights from archaeogenetics, an emerging new discipline that allows us to read our ancestors' DNA like journals chronicling personal stories of migration, Krause charts two millennia of adaption, movement and survival, culminating in the triumph of Homo Sapiens as we swept through Europe and beyond in successive waves of migration - developing everything from language, the patriarchy, disease, art and a love of pets as we did so. We also meet our ancestors, from those many of us have heard of - such as Homo Erectus and the Neanderthals - to the wildly unfamiliar but no less real: the recently discovered Denisovans, who ranged across Asia and, like humans, interbred with Neanderthals; the Aurignacians, skilled artists who, 40,000 years ago, brought about an extraordinary transformation in what our species could invent and create; the Varna, who buried their loved ones with gold long before the Pharaohs of Egypt did; and the Gravettians, big game hunters who were Europe's most successful early settlers until they perished in the face of the toughest opponent humanity had ever faced: the ice age. As well as being a radical new telling of our shared story, this book is a reminder that the global problems that keep us awake at night - climate catastrophe; the sudden emergence of deadly epidemics; refugee crises; ethnic conflict; over-population - are all things we've faced, and overcome, before.

Ancestral DNA, Human Origins, and Migrations

Ancestral DNA, Human Origins, and Migrations PDF Author: Rene J. Herrera
Publisher: Academic Press
ISBN: 0128041285
Category : Science
Languages : en
Pages : 590

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Book Description
Ancestral DNA, Human Origins, and Migrations describes the genesis of humans in Africa and the subsequent story of how our species migrated to every corner of the globe. Different phases of this journey are presented in an integrative format with information from a number of disciplines, including population genetics, evolution, anthropology, archaeology, climatology, linguistics, art, music, folklore and history. This unique approach weaves a story that has synergistic impact in the clarity and level of understanding that will appeal to those researching, studying, and interested in population genetics, evolutionary biology, human migrations, and the beginnings of our species. Integrates research and information from the fields of genetics, evolution, anthropology, archaeology, climatology, linguistics, art, music, folklore and history, among others Presents the content in an entertaining and synergistic style to facilitate a deep understanding of human population genetics Informs on the origins and recent evolution of our species in an approachable manner

Evolution of the Human Genome II

Evolution of the Human Genome II PDF Author: Naruya Saitou
Publisher: Springer Nature
ISBN: 4431569049
Category : Science
Languages : en
Pages : 260

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Book Description
This two-volume set provides a general overview of the evolution of the human genome; The first volume overviews the human genome with descriptions of important gene groups. This second volume provides up-to-date, concise yet ample knowledge on the genome evolution of modern humans. It comprises twelve chapters divided into two parts discussing “Non-neutral Evolution on Human Genes” (Part I) and “Evolution of Modern Human Populations” (Part II.) The most significant feature of this book is the continent-wise discussion of modern human dispersal using human genomic data in Part II. Recent results such as introgression of paleogenomes to modern humans, new methods such as computer simulation of global human dispersals, and new information on genes for humanness will be of particular interest to the readers. Since the euchromatin regions of the human genome was sequenced in 2003, a huge number of research papers were published on modern human evolution for a variety of populations. It is now time to summarize these achievements. This book stands out as the most comprehensive book on the modern human evolution, focusing on genomic points of view with a broad scope. Primary target audiences are researchers and graduate students in evolutionary biology.

Paleogenomics

Paleogenomics PDF Author: Charlotte Lindqvist
Publisher: Springer
ISBN: 3030047539
Category : Science
Languages : en
Pages : 427

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Book Description
Advances in genome-scale DNA sequencing technologies have revolutionized genetic research on ancient organisms, extinct species, and past environments. When it is recoverable after hundreds or thousands of years of unintended preservation, “ancient DNA” (or aDNA) is often highly degraded, necessitating specialized handling and analytical approaches. Paleogenomics defines the field of reconstructing and analyzing the genomes of historic or long-dead organisms, most often through comparison with modern representatives of the same or similar species. The opportunity to isolate and study paleogenomes has radically transformed many fields, spanning biology, anthropology, agriculture, and medicine. Examples include understanding evolutionary relationships of extinct species known only from fossils, the domestication of plants and animals, and the evolution and geographical spread of certain pathogens. This pioneering book presents a snapshot view of the history, current status, and future prospects of paleogenomics, taking a broad viewpoint that covers a range of topics and organisms to provide an up-to-date status of the applications, challenges, and promise of the field. This book is intended for a variety of readerships, including upper-level undergraduate and graduate students, professionals and experts in the field, as well as anyone excited by the extraordinary insights that paleogenomics offers.