An Operator Semigroup in Mathematical Genetics

An Operator Semigroup in Mathematical Genetics PDF Author: Adam Bobrowski
Publisher: Springer
ISBN: 3642359582
Category : Mathematics
Languages : en
Pages : 92

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Book Description
This authored monograph presents a mathematical description of the time evolution of neutral genomic regions in terms of the differential Lyapunov equation. The qualitative behavior of its solutions, with respect to different mutation models and demographic patterns, can be characterized using operator semi group theory. Mutation and drift are two of the main genetic forces, which act on genes of individuals in populations. Their effects are influenced by population dynamics. This book covers the application to two mutation models: single step mutation for microsatellite loci and single-base substitutions. The effects of demographic change to the asymptotic of the distribution are also covered. The target audience primarily covers researchers and experts in the field but the book may also be beneficial for graduate students.

An Operator Semigroup in Mathematical Genetics

An Operator Semigroup in Mathematical Genetics PDF Author: Adam Bobrowski
Publisher: Springer
ISBN: 3642359582
Category : Mathematics
Languages : en
Pages : 92

Get Book

Book Description
This authored monograph presents a mathematical description of the time evolution of neutral genomic regions in terms of the differential Lyapunov equation. The qualitative behavior of its solutions, with respect to different mutation models and demographic patterns, can be characterized using operator semi group theory. Mutation and drift are two of the main genetic forces, which act on genes of individuals in populations. Their effects are influenced by population dynamics. This book covers the application to two mutation models: single step mutation for microsatellite loci and single-base substitutions. The effects of demographic change to the asymptotic of the distribution are also covered. The target audience primarily covers researchers and experts in the field but the book may also be beneficial for graduate students.

Convergence of One-Parameter Operator Semigroups

Convergence of One-Parameter Operator Semigroups PDF Author: Adam Bobrowski
Publisher: Cambridge University Press
ISBN: 1316552950
Category : Mathematics
Languages : en
Pages : 453

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Book Description
This book presents a detailed and contemporary account of the classical theory of convergence of semigroups and its more recent development treating the case where the limit semigroup, in contrast to the approximating semigroups, acts merely on a subspace of the original Banach space (this is the case, for example, with singular perturbations). The author demonstrates the far-reaching applications of this theory using real examples from various branches of pure and applied mathematics, with a particular emphasis on mathematical biology. The book may serve as a useful reference, containing a significant number of new results ranging from the analysis of fish populations to signaling pathways in living cells. It comprises many short chapters, which allows readers to pick and choose those topics most relevant to them, and it contains 160 end-of-chapter exercises so that readers can test their understanding of the material as they go along.

From Genetics to Mathematics

From Genetics to Mathematics PDF Author: Miros?aw Lachowicz
Publisher: World Scientific
ISBN: 9812837248
Category : Science
Languages : en
Pages : 242

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Book Description
This volume contains pedagogical and elementary introductions to genetics for mathematicians and physicists as well as to mathematical models and techniques of population dynamics. It also offers a physicist's perspective on modeling biological processes. Each chapter starts with an overview followed by the recent results obtained by authors. Lectures are self-contained and are devoted to various phenomena such as the evolution of the genetic code and genomes, age-structured populations, demography, sympatric speciation, the Penna model, LotkaVolterra and other predator-prey models, evolutionary models of ecosystems, extinctions of species, and the origin and development of language. Authors analyze their models from the computational and mathematical points of view.

Mathematical Structures in Population Genetics

Mathematical Structures in Population Genetics PDF Author: I︠U︡riĭ Ilʹich Li︠u︡bich
Publisher: Springer
ISBN:
Category : Mathematics
Languages : en
Pages : 400

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Book Description


Encyclopaedia of Mathematics

Encyclopaedia of Mathematics PDF Author: Michiel Hazewinkel
Publisher: Springer Science & Business Media
ISBN: 9400903650
Category : Mathematics
Languages : en
Pages : 743

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Book Description
This ENCYCLOPAEDIA OF MATHEMATICS aims to be a reference work for all parts of mathe matics. It is a translation with updates and editorial comments of the Soviet Mathematical Encyclopaedia published by 'Soviet Encyclopaedia Publishing House' in five volumes in 1977-1985. The annotated translation consists of ten volumes including a special index volume. There are three kinds of articles in this ENCYCLOPAEDIA. First of all there are survey-type articles dealing with the various main directions in mathematics (where a rather fine subdivi sion has been used). The main requirement for these articles has been that they should give a reasonably complete up-to-date account of the current state of affairs in these areas and that they should be maximally accessible. On the whole, these articles should be understandable to mathematics students in their first specialization years, to graduates from other mathematical areas and, depending on the specific subject, to specialists in other domains of science, en gineers and teachers of mathematics. These articles treat their material at a fairly general level and aim to give an idea of the kind of problems, techniques and concepts involved in the area in question. They also contain background and motivation rather than precise statements of precise theorems with detailed definitions and technical details on how to carry out proofs and constructions. The second kind of article, of medium length, contains more detailed concrete problems, results and techniques.

Degenerate Diffusion Operators Arising in Population Biology

Degenerate Diffusion Operators Arising in Population Biology PDF Author: Charles L. Epstein
Publisher: Princeton University Press
ISBN: 0691157154
Category : Mathematics
Languages : en
Pages : 320

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Book Description
This book provides the mathematical foundations for the analysis of a class of degenerate elliptic operators defined on manifolds with corners, which arise in a variety of applications such as population genetics, mathematical finance, and economics. The results discussed in this book prove the uniqueness of the solution to the Martingale problem and therefore the existence of the associated Markov process. Charles Epstein and Rafe Mazzeo use an "integral kernel method" to develop mathematical foundations for the study of such degenerate elliptic operators and the stochastic processes they define. The precise nature of the degeneracies of the principal symbol for these operators leads to solutions of the parabolic and elliptic problems that display novel regularity properties. Dually, the adjoint operator allows for rather dramatic singularities, such as measures supported on high codimensional strata of the boundary. Epstein and Mazzeo establish the uniqueness, existence, and sharp regularity properties for solutions to the homogeneous and inhomogeneous heat equations, as well as a complete analysis of the resolvent operator acting on Hölder spaces. They show that the semigroups defined by these operators have holomorphic extensions to the right half-plane. Epstein and Mazzeo also demonstrate precise asymptotic results for the long-time behavior of solutions to both the forward and backward Kolmogorov equations.

Some Mathematical Models from Population Genetics

Some Mathematical Models from Population Genetics PDF Author: Alison Etheridge
Publisher: Springer Science & Business Media
ISBN: 3642166318
Category : Mathematics
Languages : en
Pages : 129

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Book Description
This work reflects sixteen hours of lectures delivered by the author at the 2009 St Flour summer school in probability. It provides a rapid introduction to a range of mathematical models that have their origins in theoretical population genetics. The models fall into two classes: forwards in time models for the evolution of frequencies of different genetic types in a population; and backwards in time (coalescent) models that trace out the genealogical relationships between individuals in a sample from the population. Some, like the classical Wright-Fisher model, date right back to the origins of the subject. Others, like the multiple merger coalescents or the spatial Lambda-Fleming-Viot process are much more recent. All share a rich mathematical structure. Biological terms are explained, the models are carefully motivated and tools for their study are presented systematically.

Mathematics of Genetic Diversity

Mathematics of Genetic Diversity PDF Author: J. F. C. Kingman
Publisher: SIAM
ISBN: 9781611970357
Category : Science
Languages : en
Pages : 77

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Book Description
This book draws together some mathematical ideas that are useful in population genetics, concentrating on a few aspects which are both biologically relevant and mathematically interesting.

Markov Operators, Positive Semigroups and Approximation Processes

Markov Operators, Positive Semigroups and Approximation Processes PDF Author: Francesco Altomare
Publisher: Walter de Gruyter GmbH & Co KG
ISBN: 3110366975
Category : Mathematics
Languages : en
Pages : 326

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Book Description
This research monograph gives a detailed account of a theory which is mainly concerned with certain classes of degenerate differential operators, Markov semigroups and approximation processes. These mathematical objects are generated by arbitrary Markov operators acting on spaces of continuous functions defined on compact convex sets; the study of the interrelations between them constitutes one of the distinguishing features of the book. Among other things, this theory provides useful tools for studying large classes of initial-boundary value evolution problems, the main aim being to obtain a constructive approximation to the associated positive C0-semigroups by means of iterates of suitable positive approximating operators. As a consequence, a qualitative analysis of the solutions to the evolution problems can be efficiently developed. The book is mainly addressed to research mathematicians interested in modern approximation theory by positive linear operators and/or in the theory of positive C0-semigroups of operators and evolution equations. It could also serve as a textbook for a graduate level course.

Semigroups of Linear Operators and Applications

Semigroups of Linear Operators and Applications PDF Author: Jerome A. Goldstein
Publisher: Courier Dover Publications
ISBN: 048681257X
Category : Mathematics
Languages : en
Pages : 321

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Book Description
Advanced graduate-level treatment of semigroup theory explores semigroups of linear operators and linear Cauchy problems. The text features challenging exercises and emphasizes motivation, heuristics, and further applications. 1985 edition.