Introduction to Enzyme and Coenzyme Chemistry

Introduction to Enzyme and Coenzyme Chemistry PDF Author: T. D. H. Bugg
Publisher: John Wiley & Sons
ISBN: 1118348990
Category : Science
Languages : en
Pages : 310

Get Book

Book Description
Enzymes are giant macromolecules which catalyse biochemical reactions. They are remarkable in many ways. Their three-dimensional structures are highly complex, yet they are formed by spontaneous folding of a linear polypeptide chain. Their catalytic properties are far more impressive than synthetic catalysts which operate under more extreme conditions. Each enzyme catalyses a single chemical reaction on a particular chemical substrate with very high enantioselectivity and enantiospecificity at rates which approach “catalytic perfection”. Living cells are capable of carrying out a huge repertoire of enzyme-catalysed chemical reactions, some of which have little or no precedent in organic chemistry. The popular textbook Introduction to Enzyme and Coenzyme Chemistry has been thoroughly updated to include information on the most recent advances in our understanding of enzyme action, with additional recent examples from the literature used to illustrate key points. A major new feature is the inclusion of two-colour figures, and the addition of over 40 new figures of the active sites of enzymes discussed in the text, in order to illustrate the interplay between enzyme structure and function. This new edition provides a concise but comprehensive account from the perspective of organic chemistry, what enzymes are, how they work, and how they catalyse many of the major classes of enzymatic reactions, and will continue to prove invaluable to both undergraduate and postgraduate students of organic, bio-organic and medicinal chemistry, chemical biology, biochemistry and biotechnology.

Introduction to Enzyme and Coenzyme Chemistry

Introduction to Enzyme and Coenzyme Chemistry PDF Author: T. D. H. Bugg
Publisher: John Wiley & Sons
ISBN: 1118348990
Category : Science
Languages : en
Pages : 310

Get Book

Book Description
Enzymes are giant macromolecules which catalyse biochemical reactions. They are remarkable in many ways. Their three-dimensional structures are highly complex, yet they are formed by spontaneous folding of a linear polypeptide chain. Their catalytic properties are far more impressive than synthetic catalysts which operate under more extreme conditions. Each enzyme catalyses a single chemical reaction on a particular chemical substrate with very high enantioselectivity and enantiospecificity at rates which approach “catalytic perfection”. Living cells are capable of carrying out a huge repertoire of enzyme-catalysed chemical reactions, some of which have little or no precedent in organic chemistry. The popular textbook Introduction to Enzyme and Coenzyme Chemistry has been thoroughly updated to include information on the most recent advances in our understanding of enzyme action, with additional recent examples from the literature used to illustrate key points. A major new feature is the inclusion of two-colour figures, and the addition of over 40 new figures of the active sites of enzymes discussed in the text, in order to illustrate the interplay between enzyme structure and function. This new edition provides a concise but comprehensive account from the perspective of organic chemistry, what enzymes are, how they work, and how they catalyse many of the major classes of enzymatic reactions, and will continue to prove invaluable to both undergraduate and postgraduate students of organic, bio-organic and medicinal chemistry, chemical biology, biochemistry and biotechnology.

An Introduction to Enzyme and Coenzyme Chemistry

An Introduction to Enzyme and Coenzyme Chemistry PDF Author: Tim Bugg
Publisher:
ISBN:
Category : Coenzymes
Languages : en
Pages : 0

Get Book

Book Description


Introduction to Enzyme and Coenzyme Chemistry

Introduction to Enzyme and Coenzyme Chemistry PDF Author: T. D. H. Bugg
Publisher:
ISBN:
Category :
Languages : en
Pages : 305

Get Book

Book Description
Enzyme catalysis is a topic of fundamental importance in organic, bio-organic and medicinal chemistry. This new edition of a very popular textbook provides a concise introduction to the underlying principles and mechanisms of enzyme and coenzyme action from a chemical perspective. Whilst retaining the overall structure of the first edition - preliminary chapters describe the basic principles of enzyme structure and catalysis moving through to detailed discussions of the major classes of enzyme processes in the later chapters - the book has been thoroughly updated to include information on the.

Organic Synthesis with Enzymes in Non-Aqueous Media

Organic Synthesis with Enzymes in Non-Aqueous Media PDF Author: Giacomo Carrea
Publisher: John Wiley & Sons
ISBN: 3527621733
Category : Science
Languages : en
Pages : 328

Get Book

Book Description
Closing a gap in the literature, this comprehensive book examines and discusses different non-aqueous systems from organic solvents to ionic liquids for synthetic applications, thus opening the door to new successful methods for biocatalytic reactions. It gathers into one handy source the information otherwise widely spread throughout the literature, combining useful background information with a number of synthetic examples, including industrial scale processes for pharmaceutical and fine chemicals. Extremely well structured, the text introduces the fundamentals of non-aqueous enzymology, before going on to new reaction media and synthetic applications using hydrolases and non-hydrolytic enzymes. The one-stop reference for everyone working in this hot field.

An Introduction to Enzyme Chemistry

An Introduction to Enzyme Chemistry PDF Author: P. F. Leadlay
Publisher: Royal Society of Chemistry
ISBN:
Category : Medical
Languages : en
Pages : 94

Get Book

Book Description
This monograph provides a concise account of the extent to which an enzyme's catalytic function can now be related to its detailed structure.

Enzyme Chemistry

Enzyme Chemistry PDF Author: Colin Suckling
Publisher: Springer Science & Business Media
ISBN: 9400918321
Category : Science
Languages : en
Pages : 394

Get Book

Book Description
As the first edition of this book was going through the publication process, a revolution was taking place in the technologies available for the study of enzymes. The techniques of molecular biology, especially in genetic engineering of organisms and in site specific mutagenesis of genes, were established and were being brought into use to solve many problems in in enzymology. Added to these fundamental and applied science, not least advances the possibility of generating catalysts from antibodies has become a topic of major interest. These major innovations have changed the emphasis of much bioorganic research; whereas in the past, the protein was often the 'sleeping partner' ina study, its detailed function is now the major focus of scientific interest. Similarly in industry, the potential of genetically manipulated organisms to satisfy the needs for the production of chemicals and foodstuffs has been widely recognised. The second edition of 'Enzyme Chemistry, Impact and Applications' takes on board these new develop ments whilst maintaining the overall aims and views of the first edition. Many of the chapters have been completely rewritten to take account of advances in the last five years especially with regard to the impact of biologically based technologies. Although the book continues to approach its subject matter from the point of view of the chemist, the increased interdisciplinary content of much modern science will be obvious from the discussion.

Introduction to Biocatalysis Using Enzymes and Microorganisms

Introduction to Biocatalysis Using Enzymes and Microorganisms PDF Author: S. M. Roberts
Publisher: Cambridge University Press
ISBN: 9780521436854
Category : Medical
Languages : en
Pages : 216

Get Book

Book Description
This book gives an introduction to biotransformations, the practice of harnessing biological catalysts for the preparation of useful chemicals.

Introduction to Enzyme and Coenzyme Chemistry

Introduction to Enzyme and Coenzyme Chemistry PDF Author: T. D. H. Bugg
Publisher: John Wiley & Sons
ISBN: 1405148004
Category : Science
Languages : en
Pages : 304

Get Book

Book Description
Enzyme catalysis is a topic of fundamental importance in organic, bio-organic and medicinal chemistry. This new edition of a very popular textbook provides a concise introduction to the underlying principles and mechanisms of enzyme and coenzyme action from a chemical perspective. Whilst retaining the overall structure of the first edition – preliminary chapters describe the basic principles of enzyme structure and catalysis moving through to detailed discussions of the major classes of enzyme processes in the later chapters – the book has been thoroughly updated to include information on the most recent advances in our understanding of enzyme action. A major feature of the second edition is the inclusion of two-colour figures of the active sites of enzymes discussed in the text, in order to illustrate the interplay between enzyme structure and function. Problems, with outline answers, at the end of each chapter give the student the chance to the check their understanding of the material. As a concise but comprehensive account, Introduction to Enzyme and Coenzyme Chemistry will continue to prove invaluable to both undergraduate and postgraduate students of organic, bio-organic and medicinal chemistry. Tim Bugg is professor of biological chemistry in the Department of Chemistry, University of Warwick, UK.

Introduction to Enzymology

Introduction to Enzymology PDF Author: Alan H. Mehler
Publisher: Elsevier
ISBN: 1483258475
Category : Science
Languages : en
Pages : 434

Get Book

Book Description
Introduction to Enzymology focuses on the processes, methodologies, reactions, and approaches involved in enzyme chemistry. The book first offers information on the hydrolysis of peptides and proteins and fermentation and oxidation of major metabolic fuels. Discussions focus on oxidation of fatty acids, alternative pathways of carbohydrate metabolism, Krebs citric acid cycle, free energy and the concept of bond energy, pyruvate oxidation and acetyl coenzyme A formation, and glycolysis. The text then elaborates on the transfer of oxygen, hydrogen, and electrons and sugars and sugar derivatives. The publication takes a look at polynucleotides and their components, amino acids, and acids and acid derivatives. Topics include carbonic anhydrase, mechanism of action of pyridoxal phosphate enzymes, aromatic ring biosynthesis and metabolism of phenylalanine and tyrosine, metabolism of sulfur-containing amino acids, and oxidation of amino acids. The book is a valuable reference for chemists and researchers interested in enzymology.

Enzymes and Enzyme Technology

Enzymes and Enzyme Technology PDF Author: Anil Kumar
Publisher:
ISBN: 9788130927503
Category : Science
Languages : en
Pages : 0

Get Book

Book Description
Beginning with the nomenclature and classification of enzymes this book covers topics on synzymes, abzymes, enzyme immobilisation, mnemonical enzymes, ribozymes etc. Techniques used in enzyme purification are described in detail. The book is written in a simple language, easily understandable to students, keeping in mind the requirements of enzymes and enzyme technology at the postgraduate level. This book should be invaluable to students interested in the fundamentals of enzyme technology.