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Author: Adam Schneeweiss
Publisher: Springer Science & Business Media
ISBN: 3642970664
Category : Medical
Languages : en
Pages : 182
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Book Description
All aspects of nitrate therapy, including conventional and new formulations and delivery systems, are covered in this book. For each drug the formulation, mechanism of action, indications, effects, adverse reactions and special problems are systematically described. The use of nitrates in specific population groups, such as infants, children and the elderly, is dealt with separately. The book is updated, based not only on the world literature but also on the most recent conference presentations, and provides the reader with thorough and practice-oriented coverage.
Author: Adam Schneeweiss
Publisher: Springer Science & Business Media
ISBN: 3642970664
Category : Medical
Languages : en
Pages : 182
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Book Description
All aspects of nitrate therapy, including conventional and new formulations and delivery systems, are covered in this book. For each drug the formulation, mechanism of action, indications, effects, adverse reactions and special problems are systematically described. The use of nitrates in specific population groups, such as infants, children and the elderly, is dealt with separately. The book is updated, based not only on the world literature but also on the most recent conference presentations, and provides the reader with thorough and practice-oriented coverage.
Author: Adam Schneeweiss
Publisher:
ISBN: 9783642970672
Category :
Languages : en
Pages : 192
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Book Description
Author: Adam Schneeweiss
Publisher: Springer Science & Business Media
ISBN: 3642758347
Category : Medical
Languages : en
Pages : 206
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Book Description
Nitrates have been for many years the cornerstone of cardiovascular therapy for various indications. Not only have nitrates stood the test of time for treatment of chronic stable angina pectoris, but the indications for them have markedly ex panded. They now include all forms of angina pectoris and myocardial ischemia, congestive heart failure and hypertensive emergencies. The beneficial effects of nitrates in all these conditions result from their vasodilatory properties, but it is still unclear whether the central or peripheral effects predominate in the thera peutic mechanism. Recently nitrates have been shown to fulfill the most important requirement for each and every drug - to reduce mortality. A large scale study revealed that isosorbide dinitrate, combined with hydralazine, reduced long-term mortality by 28% in patients with congestive heart failure. This finding will certainly stimulate research on nitrates, and it might be expected that interest in these drugs will markedly increase. The primarily used nitrates in clinical practice are nitroglycerin and the com plex organic nitrates, mainly isosorbide dinitrate. The organic mononitrates are now under clinical investigation, and isosorbide-5-mononitrate (IS-5-MN) appears to be especially promising.
Author: P. Needleman
Publisher: Springer Science & Business Media
ISBN: 364266024X
Category : Medical
Languages : en
Pages : 206
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Book Description
Nitroglycerin and other organic nitrates have been used for over a century in the treatment of angina pectoris. Millions of patients, throughout the world, have placed nitroglycerin tablets under the tongue and have experienced rapid and dramatic relief from the chest pain that frequently occurs as a manifestation of disease of the coronary arteries. The empirical observation of the safe use of nitrates for tile alleviation of the symptoms of angina have led to their widespread medical acceptance. The use of organic nitrates preceded any knowledge of their mechanism of action or their ultimate metabolic fate. Thus, more simply stated, although sub lingual nitrates helped the patients, little was known concerning what these drugs do to the body or what the body does to the drugs. A substantial number of investigators have focused on these questions especially during the last two decades. We now have considerably more insight into the pathways of degradation of organic nitrates and the relationship of the metabolic processes to the biological action of these agents. Similarly, considerable effort has been expended in understanding the mechanism of action of these agents directly on vascular smooth muscle and on cardiac work and performance. Finally, there is a more substantive understanding of the physiology of the coronary circulation as well as the" pathophysiologic manifestations of myocardial disease.
Author: Istvan Bogardi
Publisher: Springer Science & Business Media
ISBN: 3642760406
Category : Technology & Engineering
Languages : en
Pages : 438
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Book Description
The nitrate content of drinking water is rising at an alarming rate in several regions of NATO countries and elsewhere in the world. The increase is due to lack of proper sewage treatment, and primarily to excess fertilizer application. Also, eutrophication in several coastal areas is triggered by high nitrate concentrations. The main purpose of this book is to integrate scientific knowledge related to exposure assessment, health consequences and control of nitrate contamination in water. The motivation is related to the magnitude, the possible adverse health effects, and the high cost of control ling nitrate contamination. Future research tasks are defined by an interaction among hydro logists, toxicologists and environmental engineers in an integrated framework for nitrate risk management. The target readership of this book is a mix of university colleagues, practitioners from both the private and public sectors and advanced graduate students working with the hydrological, health science or environmental engineering aspects of nitrate contamination. The main conclusions include: 1. For risk assessment purposes, knowledge and sufficiently accurate models are available to predict nitrate load and its fate in water under changes in land use. 2. Once agricultural exposure controls are implemented, the response times in ground water may be so long as to make controls unrealistic. 3. It is still unknown whether agricultural best management practice is a compromise between nitrate risk reduction and agricultural revenue. 4. The current drinking water guidelines of 10 mg/L NOrN need not be changed.
Author: Franco Cavalli
Publisher: Springer Science & Business Media
ISBN: 1461326079
Category : Medical
Languages : en
Pages : 644
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Book Description
Malignant lymphomas remain a fascinating research topic for clinicians as well as basic scientists. Rapidly increasing technical sophistication, ex panded knowledge and broader implications of new findings underline the need for a forum to integrate the latest developments in the multiple areas involved in the challenging study of lymphoid malignancies. This volume includes contributions of renowned experts and is based on a selection of papers presented at the Second International Conference on Malignant Lymphomas that was held in Lugano, Switzerland, in June 1984. Updated information is provided on various experimental fields including cell biolo gy, immunology, genetics and cell biochemistry. Particular attention has been given to special clinical entities such as the lymphomas associated with the Acquired Immune Deficiency Syndrome. Recent advances in the treat of Hodgkin's disease, ncin-Hodgkin's lymphomas and childhood lym ment phomas are highlighted with emphasis on growing experience with new therapeutic approaches including monoclonal antibodies and bone marrow transplantation. The contents of the volume reflect and translate numerous avenues of exploration. While there might be some unavoidable overlap, most appear essentially complementary. The intent of the Program Committee of the Second International Conference on Malignant Lymphomas was to promote further interactions between all those who are devoting major efforts to elucidate the nature of these diseases or their optimal therapy. This volume will hopefully amplify this objective. The Editors wish to thank the contributors for delivering the manuscripts on schedule.
Author:
Publisher: ScholarlyEditions
ISBN: 1464957193
Category : Science
Languages : en
Pages : 20
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Book Description
Nitrates: Advances in Research and Application: 2011 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Nitrates in a compact format. The editors have built Nitrates: Advances in Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Nitrates in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Nitrates: Advances in Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Author: Sushma Dave
Publisher: Elsevier
ISBN: 0323900666
Category : Technology & Engineering
Languages : en
Pages : 596
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Book Description
Advanced Nanomaterials for Point of Care Diagnosis and Therapy provides an overview of technological and emerging novel trends in how point-of-care diagnostic devices are designed, miniaturized built, and delivered at different healthcare set ups. It describes the significant technological advances in fundamental diagnostic components and recent advances in fully integrated devices designed for specific clinical use. The book covers state-of-the-art fabrication of advances materials with broad spectrum therapeutic applications. It includes drug delivery, biosensing, bioimaging and targeting, and outlines the development of inexpensive, effective and portable in vitro diagnostics tools for any purpose that can be used onsite. Sections also discuss drug delivery, biosensing, bioimaging and targeting and various metal, metal oxide and non-metal-based nanomaterials that are developed, surface modified, and are being explored for diagnosis, targeting, drug delivery, drug release and imaging. The book concludes with current needs and future challenges in the field. Outlines the needs and challenges of point-of-care diagnostics Describes the fundamentals of application of nanomaterials as interesting building blocks for biosensing Overviews the different detection methods offered by using nanomaterials Explains the advantages and drawbacks of nanomaterial-based sensing strategies Describes the opportunities offered by technology as a cost-efficient biosensing platform
Author: Virginia Poole Arcangelo
Publisher: Lippincott Williams & Wilkins
ISBN: 1975160606
Category : Medical
Languages : en
Pages : 1989
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Book Description
Be ready to prescribe and administer drugs safely and effectively, with the fully updated Pharmacotherapeutics for Advanced Practice, 5th Edition. Anchored in pharmacology and the principles of therapeutics, and written by experts in the field, this is your road map to effective drug therapies. Learn to correctly identify a disorder, review the drugs used to treat it, and select the optimal therapy. With expert direction on more than 50 common disorders, this is the ideal resource for advanced practice clinicians and students learning pharmacotherapeutics, and a go-to reference for experienced clinicians.
Author: National Library of Medicine (U.S.)
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 968
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Book Description
