Advancement in Gene Set Analysis: Gaining Insight From High-throughput Data PDF Download
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Author: Farhad Maleki
Publisher: Frontiers Media SA
ISBN: 2889764230
Category : Science
Languages : en
Pages : 195
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Book Description
Author: Farhad Maleki
Publisher: Frontiers Media SA
ISBN: 2889764230
Category : Science
Languages : en
Pages : 195
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Book Description
Author: Carlos Fernandez-Lozano
Publisher: MDPI
ISBN: 3036509445
Category : Science
Languages : en
Pages : 314
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Book Description
• Real-world problems can be high-dimensional, complex, and noisy • More data does not imply more information • Different approaches deal with the so-called curse of dimensionality to reduce irrelevant information • A process with multidimensional information is not necessarily easy to interpret nor process • In some real-world applications, the number of elements of a class is clearly lower than the other. The models tend to assume that the importance of the analysis belongs to the majority class and this is not usually the truth • The analysis of complex diseases such as cancer are focused on more-than-one dimensional omic data • The increasing amount of data thanks to the reduction of cost of the high-throughput experiments opens up a new era for integrative data-driven approaches • Entropy-based approaches are of interest to reduce the dimensionality of high-dimensional data
Author: Sajal Chakraborti
Publisher: Elsevier
ISBN: 0323956882
Category : Science
Languages : en
Pages : 2974
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Book Description
Phospholipases in Physiology and Pathology presents a comprehensive overview on the physiology and pathology of phospholipases. This seven-volume set considers the biochemical and molecular mechanisms of normal and abnormal cell function upon dysregulation of phospholipases in different diseases. Volumes cover signal transduction mechanisms, implications in cancer, infectious diseases, neural diseases, cardiovascular diseases and other diseases, implications in inflammation, apoptosis, gene expression and non-coding RNAs, the role of natural and synthetic compounds, and stem cell therapies, nanotechnology-based therapies, and more. Together, these volumes give researchers critical insight on the mechanistic and therapeutic aspects of phospholipases. - Discusses the biochemical and molecular mechanisms of normal and abnormal cell function in different disease processes - Covers a wide range of basic and translational research appropriate for scientists engaged in studying the regulation of phospholipases from interdisciplinary perspectives - Features state-of-the-art chapter contributions from international leaders in the field
Author: National Research Council
Publisher: National Academies Press
ISBN: 0309180716
Category : Science
Languages : en
Pages : 102
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Book Description
The U.S. Department of Energy (DOE) promotes scientific and technological innovation to advance the national, economic, and energy security of the United States. Recognizing the potential of microorganisms to offer new energy alternatives and remediate environmental contamination, DOE initiated the Genomes to Life program, now called Genomics: GTL, in 2000. The program aims to develop a predictive understanding of microbial systems that can be used to engineer systems for bioenergy production and environmental remediation, and to understand carbon cycling and sequestration. This report provides an evaluation of the program and its infrastructure plan. Overall, the report finds that GTL's research has resulted in and promises to deliver many more scientific advancements that contribute to the achievement of DOE's goals. However, the DOE's current plan for building four independent facilities for protein production, molecular imaging, proteome analysis, and systems biology sequentially may not be the most cost-effective, efficient, and scientifically optimal way to provide this infrastructure. As an alternative, the report suggests constructing up to four institute-like facilities, each of which integrates the capabilities of all four of the originally planned facility types and focuses on one or two of DOE's mission goals. The alternative infrastructure plan could have an especially high ratio of scientific benefit to cost because the need for technology will be directly tied to the biology goals of the program.
Author: Malik Yousef
Publisher:
ISBN: 9781627037488
Category : RNA
Languages : en
Pages : 333
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Book Description
In miRNomics: MicroRNA Biology and Computational Analysis, expert researchers in the field present an overview of the current state of the art and aim to put the respective areas of research into a larger perspective. These include methods and techniques ranging from miRNA biogenesis, their biological function, computational analyses to their medical implications and applications. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, miRNomics: MicroRNA Biology and Computational Analysis seeks to aid scientists in the further study into miRNA research and statistics.
Author: Sam Thiagalingam
Publisher: Cambridge University Press
ISBN: 0521493390
Category : Mathematics
Languages : en
Pages : 597
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Book Description
An overview of the current systems biology-based knowledge and the experimental approaches for deciphering the biological basis of cancer.
Author: Urs Schmidhalter
Publisher: Frontiers Media SA
ISBN: 2889711595
Category : Science
Languages : en
Pages : 399
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Book Description
Author: Zhichao Liu
Publisher: Frontiers Media SA
ISBN: 2889661628
Category : Science
Languages : en
Pages : 297
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Book Description
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Author: Lihong Peng
Publisher: Frontiers Media SA
ISBN: 2832510345
Category : Science
Languages : en
Pages : 164
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Book Description
Author: Deepesh Bhatt
Publisher: Elsevier
ISBN: 044321624X
Category : Science
Languages : en
Pages : 489
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Book Description
Applied Biotechnology Strategies to Combat Plant Abiotic Stress investigates the causal molecular factors underlying the respective mechanisms orchestrated by plants to help alleviate abiotic stress in which Although knowledge of abiotic stresses in crop plants and high throughput tools and biotechnologies is avaiable, in this book, a systematic effort has been made for integrating omics interventions across major sorts of abiotic stresses with special emphasis to major food crops infused with detailed mechanistic understanding, which would furthermore help contribute in dissecting the interdisciplinary areas of omics-driven plant abiotic stress biology in a much better manner. In 32 chapters Applied Biotechnology Strategies to Combat Plant Abiotic Stress focuses on the integration of multi-OMICS biotechnologies in deciphering molecular intricacies of plant abiotic stress namely drought, salt, cold, heat, heavy metals, in major C3 and C4 food crops. Together with this, the book provides updated knowledge of common and unique set of molecular intricacies playing a vital role in coping up severe abiotic stresses in plants deploying multi-OMICS approaches This book is a valuable resource for early researchers, senior academicians, and scientists in the field of biotechnology, biochemistry, molecular biology, researchers in agriculture and, crops for human foods, and all those who wish to broaden their knowledge in the allied field. - Describes biotechnological strategies to combat plant abiotic stress - Covers the latest evidence based multipronged approaches in understanding omics perspective of stress tolerance - Focuses on the integration of multi-OMICS technologies in deciphering molecular intricacies of plant abiotic stress
