Acyclic Stereoselection in [alpha]-amidoalkylation Reactions PDF Download
Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download Acyclic Stereoselection in [alpha]-amidoalkylation Reactions PDF full book. Access full book title Acyclic Stereoselection in [alpha]-amidoalkylation Reactions by Clark Steven Davis. Download full books in PDF and EPUB format.
![Acyclic Stereoselection in [alpha]-amidoalkylation Reactions PDF](https://books.google.com/books/content/images/frontcover/Z2uxNwAACAAJ?fife=w150-h200)
Author: Clark Steven Davis
Publisher:
ISBN:
Category : Amino acids
Languages : en
Pages : 228
Get Book Here
Book Description
![Acyclic Stereoselection in [alpha]-amidoalkylation Reactions PDF](https://books.google.com/books/content/images/frontcover/Z2uxNwAACAAJ?fife=w80-h100)
Author: Clark Steven Davis
Publisher:
ISBN:
Category : Amino acids
Languages : en
Pages : 228
Get Book Here
Book Description
![Stereoselective Synthesis of Acyclic Chiral Amines by [alpha]-amidoalkylation PDF](https://books.google.com/books/content/images/frontcover/PtzPNwAACAAJ?fife=w80-h100)
Author: Lee Tai Liu
Publisher:
ISBN:
Category : Alkylation
Languages : en
Pages : 290
Get Book Here
Book Description
Author: Erick M. Carreira
Publisher: John Wiley & Sons
ISBN: 9783527324521
Category : Science
Languages : en
Pages : 664
Get Book Here
Book Description
Die wichtigsten und nützlichsten Methoden der modernen stereoselektiven Synthese sind in diesem Band zusammengefasst. Viele anschauliche Beispiele für die Darstellung von Wirkstoffen und Naturstoffen regen zur gezielten Abwandlung und Integration in eigene Synthesewege an. Dabei geht es den Autoren weniger darum, das Gebiet in seiner Gesamtheit darzustellen; vielmehr versuchen sie, die wirklich grundlegenden Ansätze auszuwählen, die jeder organische Synthesechemiker kennen und anwenden sollte.
![Novel Stereoselective Aldol Reactions of [alpha]-trialkylsilyl Substituted Acyclic Acetals PDF](https://books.google.com/books/content/images/frontcover/q9iItgAACAAJ?fife=w80-h100)
Author: Tarakeshwar Vishwanath Anklekar
Publisher:
ISBN:
Category :
Languages : en
Pages : 296
Get Book Here
Book Description
Author: Johnathan Edward Schultz
Publisher:
ISBN:
Category :
Languages : en
Pages :
Get Book Here
Book Description
Herein are described strategies for the asymmetric synthesis of acyclic tetrasubstituted stereocenters using palladium-catalyzed allylic alkylation. In particular prochiral nucleophiles are exploited for the synthesis of acyclic alpha tertiary hydroxyketones, fully substituted nitroalkanes, and all-carbon quaternary stereocenters. The problem of O-alkylation in benzylic nitronate synthesis was overcome by the use of a decarboxylative asymmetric allylic alkylation of allyl alpha nitroesters. Extensive screening of reaction conditions revealed a unique ligand and solvent combination that proved crucial for achieving high chemo- and enantioselectivity in this challenging reaction. Substrates were readily synthesized via a combinatorial cross-Claisen / alpha arylation protocol, and the method was highlighted by chemoselective functional group interconversions of a highly elaborated substrate. Boronic acids were exploited as templates of ene-diolate systems to solve a longstanding problem of direct asymmetric C-alkylation of alpha hydroxyketones. This process was rendered chemo-, regio-, and enantioselective in allylation reactions, while point and axial chirality were efficiently set in allylic alkylations of racemic allene substrates via a dynamic kinetic asymmetric transformation. This method represents one of the first examples where point and axial chirality are effectively set in allylic alkylation. As a follow-up to this work, enol boranes were found to be effective pronucleophiles in palladium-catalyzed allylic alkylation reactions. A 1,4-hydroboration reaction was exploited for the thermal generation of regio-defined enol boranes, and a unique electron-deficient ligand was found to exhibit differential reactivity in the subsequent alkylation reaction. This chemistry was further extended to provide a room temperature alkylation of ester derived enol boranes, in particular, unactivated esters. A preparative application was demonstrated in the synthesis of acyclic all-carbon quaternary stereocenters, where the stereoselectivity was a function of the identities of a chiral auxiliary, a chiral ligand, and a designer leaving group. It is hoped that this chemistry may spur broader interest in metal-catalyzed reactions of enol boranes.
![Acyclic N-acyliminium Ions in the Synthesis of [alpha]-amino Acids PDF](https://books.google.com/books/content/images/frontcover/X6IyAAAAIAAJ?fife=w80-h100)
Author: Hendrik Harm Mooiweer
Publisher:
ISBN:
Category : Amino acids
Languages : en
Pages : 180
Get Book Here
Book Description
Author: Navjeet Kaur
Publisher: Elsevier
ISBN: 0128202831
Category : Science
Languages : en
Pages : 526
Get Book Here
Book Description
Metal and Nonmetal Assisted Synthesis of Six-Membered Heterocycles provides a useful guide to key approaches being explored in this area. The volume highlights synthetic approaches and catalytic options that facilitate the construction of multiple substituted molecules under mild conditions from easily available starting substrates. Drawing on the experience of its expert author, the book is a useful guide on the key approaches being explored in this area. Following a user-friendly structure based on specific six-membered heterocycle ring groups, this volume highlights synthetic approaches and catalytic options that facilitate the construction of multiple substituted molecules under mild conditions from easily available starting substrates. Highlights new methodologies for the synthesis of different six-membered heterocycles Provides an up-to-date overview of this fast-moving field with an easy-to-use structure Includes novel approaches used in the study and application of catalysts in synthetic organic reactions
Author: Belakatte Parameshwarappa Nandeshwarappa
Publisher: BoD – Books on Demand
ISBN: 1789859433
Category : Science
Languages : en
Pages : 250
Get Book Here
Book Description
The book ‘Organic Synthesis - A Nascent Relook’ is a compendium of the recent progress in all aspects of organic chemistry including bioorganic chemistry, organo-metallic chemistry, asymmetric synthesis, heterocyclic chemistry, natural product chemistry, catalytic, green chemistry and medicinal chemistry, polymer chemistry, as well as analytical methods in organic chemistry. The book presents the latest developments in these fields. The chapters are written by chosen experts who are internationally known for their eminent research contributions. Organic synthesis is the complete chemical synthesis of a target molecule. In this book, special emphasis is given to the synthesis of various bioactive heterocycles. Careful selection of various topics in this book will serve the rightful purpose for the chemistry community and the industrial houses at all levels.
Author:
Publisher:
ISBN:
Category : Chemistry, Organic
Languages : en
Pages : 68
Get Book Here
Book Description
References to literature (mostly journal articles) dealing with individual or classes of chemical compounds, name reactions, and specific processes or phenomena. Also includes foreign-language materials. Citations subdivided under each letter into sections dealing with compounds, name reactions, and processes or phenomena. Each entry gives chemical entity, author(s), and other bibliographical information.
Author: Christopher T. Walsh
Publisher: Royal Society of Chemistry
ISBN: 1788010760
Category : Science
Languages : en
Pages : 787
Get Book Here
Book Description
This textbook describes the types of natural products, the biosynthetic pathways that enable the production of these molecules, and an update on the discovery of novel products in the post-genomic era.
