A Case-control Study of Lifetime Participation in Recreational Physical Activity and Changes in Body Size in Relation to Breast Cancer PDF Download
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Author: Sybil Eng
Publisher:
ISBN:
Category :
Languages : en
Pages : 826
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Author: Sybil Eng
Publisher:
ISBN:
Category :
Languages : en
Pages : 826
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Author: Suzanne M. Shoff
Publisher:
ISBN:
Category :
Languages : en
Pages : 27
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Book Description
This postdoctoral training award supports studies to describe elements of energy balance and breast cancer incidence. The modifying effect of early-life body size and weight change on associations between early-life physical activity and breast cancer risk was evaluated using extant data from a case-control study of breast cancer. Cases (n=6888) were identified through four state-wide cancer registries; controls (n=9529) were randomly selected from population lists. Results suggest that, in premenopausal women, the relation between early-life physical activity and breast cancer risk is similar across all strata of early-life body size and weight change. In postmenopausal women, results suggest that risk reduction associated with physical activity may be greatest in women who were heaviest at age 18, and in women who maintained a stable weight between age 18 and 5 years prior to diagnosis, independent of initial weight. Preliminary data were obtained on intentional weight loss and weight reduction methods from the successful addition of relevant questions to an on-going case-control study of breast cancer. Responses to these questions suggest small, but potentially important, differences between cases and controls regarding patterns of intentional weight loss, choice of weight reduction method, and amount of weight lost.
Author: Kerry S. Courneya
Publisher: Springer Science & Business Media
ISBN: 3642042317
Category : Medical
Languages : en
Pages : 389
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Book Description
This book explores in depth the relation between physical activity and cancer control, including primary prevention, coping with treatments, recovery after treatments, long-term survivorship, secondary prevention, and survival. The first part of the book presents the most recent research on the impact of physical activity in preventing a range of cancers. In the second part, the association between physical activity and cancer survivorship is addressed. The effects of physical activity on supportive care endpoints (e.g., quality of life, fatigue, physical functioning) and disease endpoints (e.g., biomarkers, recurrence, survival) are carefully analyzed. In addition, the determinants of physical activity in cancer survivors are discussed, and behavior change strategies for increasing physical activity in cancer survivors are appraised. The final part of the book is devoted to special topics, including the relation of physical activity to pediatric cancer survivorship and to palliative cancer care.
Author:
Publisher:
ISBN:
Category : Dissertations, Academic
Languages : en
Pages : 756
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Author:
Publisher:
ISBN:
Category : Cancer
Languages : en
Pages : 1030
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Author: Jay R. Harris
Publisher: Lippincott Williams & Wilkins
ISBN: 1451148704
Category : Medical
Languages : en
Pages : 3432
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Book Description
Completely revised and updated, and now in full color throughout, the Fourth Edition of this definitive reference is a must for all clinicians who treat breast diseases. Leading experts summarize the current knowledge of breast diseases, including their clinical features, management, underlying biologies, and epidemiologies. In addition to complete coverage of malignant breast diseases, benign diseases are discussed in relation to subsequent breast cancer development. The book reviews all major clinical trials and summarizes the information they provide on early detection and management of breast cancer. Close attention is also given to the increasing importance of molecular biology and genetics in this field. This edition features more than thirty new contributors, fourteen new or completely rewritten chapters, and more clinically oriented chapters. A companion Website will offer the fully searchable text and an image bank. Also included with this edition is the Anatomical Chart Company's Breast Anatomy and Disorders Pocket Guide. This durable, portable folding pocket guide provides a visual and textual overview of breast anatomy, disorders, and breast self-examination. With a write-on, wipe-off laminated surface, this guide is perfect for the on-the-go practitioner to show patients, caregivers, and families.
Author: Jodi Wilson
Publisher:
ISBN:
Category : University of Ottawa theses
Languages : en
Pages :
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Although there is consistent evidence of an inverse association between physical activity and colorectal cancer (CRC), it is unclear whether physical activity has to be lifelong in order to protect against CRC, or whether there are critical time periods in which physical activity is most protective. This thesis investigated the association between recreational physical activities in specific age periods and across the lifetime and CRC risk in data from a population-based case control study (n=1395) in Newfoundland and Labrador. There were no significant associations between recreational physical activity at any age period or across the lifetime. Lack of association with activity in early adulthood is consistent with other studies in which this has been investigated. Lack of association in later life and across the lifetime may in part be explained by low levels of recreational physical activity, with only 30% of participants meeting World Cancer Research Fund cancer prevention recommendations.
Author:
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ISBN:
Category : Dissertation abstracts
Languages : en
Pages : 776
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Author: Lindsay Clare Kobayashi
Publisher:
ISBN:
Category :
Languages : en
Pages : 372
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Background: Moderate-to-vigourous intensity physical activity (MVPA) is among the few modifiable factors known to reduce breast cancer risk. However, the independent effects of leisure-time, household, and occupational MPVA by age period across the life course remain poorly understood. Whether these effects differ by menopausal status and by tumour subtypes defined by the estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor-2 (HER2) is unknown. An understanding of these issues will help advance policy and public health action targeting breast cancer prevention through physical activity. Methods: A case-control study of 1,011 incident breast cancer cases and 1,014 cancer-free controls aged 40-80 years was conducted from 2006-2010 in Vancouver, British Columbia (BC). Lifetime leisure-time, household, and occupational MVPA were assessed by questionnaire and mean MET-hrs/week of each were calculated for age periods 12-17, 18-34, 35-49, and [greater or equal to] 50 years and the total lifetime. Odds ratios for pre- and post-menopausal breast cancer risk associated with each activity domain across age periods were estimated using unconditional logistic regression, and odds ratios for risks of ER/PR-defined and ER/PR/HER2-defined breast tumours were estimated using unconditional polytomous logistic regression. Results: Among post-menopausal women, lifetime leisure-time and household MVPA reduced breast cancer risk by approximately 50% at volumes equal to 3 hours per week of running and 21 hours per week of active household work. MVPA reduced risk at all age periods across the life course, particularly during adulthood. Effects of leisure-time MVPA appeared restricted to HER2- tumours. Household MVPA reduced risk for ER/PR+ tumours, regardless of HER2 status. MVPA was not associated with pre-menopausal breast cancer risk, except occupational MVPA performed during ages 18-34 was associated with a doubling in risk. Conclusions: MVPA is a lifestyle factor women may engage in to reduce post-menopausal breast cancer risk. Results suggest HER2 may be implicated in anti-breast carcinogenic effects of leisure-time MVPA. Increased risk associated with occupational MVPA may be due to occupational exposures related to job intensity. Further research on specific aspects of weekly MVPA energy expenditure dose required to reduce breast cancer risk will aid in refining physical activity recommendations for breast cancer prevention.
Author: R.D. Mann
Publisher: CRC Press
ISBN: 9781850703990
Category : Medical
Languages : en
Pages : 321
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Book Description
This book covers a topic of considerable current interest and presents many of the most significant research findings available to date. Workers at the forefront of research on hormone replacement therapy and the implications for the risk of breast cancer were invited to attend a special Conference at the Royal Society of Medicine in London in September, 1991, where the latest data were presented to a distinguished audience and the implications of this research were discussed. The volume reviews various aspects of HRT and breast cancer, the physiology of the menopause, the current use of HRT in practice, osteoporosis and epidemiology and presents results from a range of European, American and Australian studies on the role of breast cancer and HRT, finishing with an overview of benefits, use and cost-effectiveness and a general summary. The book represents a definitive statement of current knowledge in this field and an informative update on the implications of recent research. It will be a valuable addition of special significance to the libraries of all those concerned with hormone replacement therapy and the study of breast cancer.
