Unravelling the Double Helix

Unravelling the Double Helix PDF Author: Gareth Williams
Publisher: Weidenfeld & Nicolson
ISBN: 1474609384
Category : Science
Languages : en
Pages : 500

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Book Description
DNA. The double helix; the blueprint of life; and, during the early 1950s, a baffling enigma that could win a Nobel Prize. Everyone knows that James Watson and Francis Crick discovered the double helix. In fact, they clicked into place the last piece of a huge jigsaw puzzle that other researchers had assembled over decades. Researchers like Maurice Wilkins (the 'Third Man of DNA') and Rosalind Franklin, famously demonised by Watson. Not forgetting the 'lost heroes' who fought to prove that DNA is the stuff of genes, only to be airbrushed out of history. In Unravelling the Double Helix, Professor Gareth Williams sets the record straight. He tells the story of DNA in the round, from its discovery in pus-soaked bandages in 1868 to the aftermath of Watson's best-seller The Double Helix a century later. You don't need to be a scientist to enjoy this book. It's a page-turner that unfolds like a detective story, with suspense, false leads and treachery, and a fabulous cast of noble heroes and back-stabbing villains. But beware: some of the science is dreadful, and the heroes and villains may not be the ones you expect.

Unravelling the Double Helix

Unravelling the Double Helix PDF Author: Gareth Williams
Publisher: Simon and Schuster
ISBN: 1643132830
Category : Science
Languages : en
Pages : 607

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Book Description
Unraveling the Double Helix covers the most colorful period in the history of DNA, from the discovery of "nuclein" in the late 1860s to the publication of James Watson's The Double Helix in 1968. These hundred years included the establishment of the Nobel Prize, antibiotics, x-ray crystallography, the atom bomb and two devastating world wars—events which are strung along the thread of DNA like beads on a necklace. The story of DNA is a saga packed with awful mistakes as well as brilliant science, with a wonderful cast of heroes and villains. Surprisingly, much of it is unfamiliar. The elucidation of the double helix was one of the most brilliant gems of twentieth century science, but some of the scientists who paved the way have been airbrushed out of history. James Watson and Francis Crick solved a magnificent mystery, but Gareth Williams shows that their contribution was the last few pieces of a gigantic jigsaw puzzle assembled over several decades.The book is comprehensive in scope, covering the first century of the history of DNA in its entirety, including the eight decades that have been neglected by other authors. It also explores the personalities of the main players, the impact of their entanglement with DNA, and what unique qualities make great scientists tick.

Francis Crick

Francis Crick PDF Author: Matt Ridley
Publisher: Harper Collins
ISBN: 0062200666
Category : Biography & Autobiography
Languages : en
Pages : 228

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Book Description
Francis Crick—the quiet genius who led a revolution in biology by discovering, quite literally, the secret of life—will be bracketed with Galileo, Darwin, and Einstein as one of the greatest scientists of all time. In his fascinating biography of the scientific pioneer who uncovered the genetic code—the digital cipher at the heart of heredity that distinguishes living from non-living things—acclaimed bestselling science writer Matt Ridley traces Crick's life from middle-class mediocrity in the English Midlands through a lackluster education and six years designing magnetic mines for the Royal Navy to his leap into biology at the age of thirty-one and its astonishing consequences. In the process, Ridley sheds a brilliant light on the man who forever changed our world and how we understand it.

The Annotated and Illustrated Double Helix

The Annotated and Illustrated Double Helix PDF Author: James D. Watson
Publisher: Simon and Schuster
ISBN: 1476715513
Category : Science
Languages : en
Pages : 361

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Book Description
On the fiftieth anniversary of Watson and Crick receiving the Nobel Prize, a freshly annotated and illustrated edition of The Double Helix provides new insights into a scientific revolution. Published to mark the fiftieth anniversary of the Nobel Prize for Watson and Crick’s discovery of the structure of DNA, an annotated and illustrated edition of this classic book gives new insights into the personal relationships between James Watson, Frances Crick, Maurice Wilkins, and Rosalind Franklin, and the making of a scientific revolution.

My Sister Rosalind Franklin

My Sister Rosalind Franklin PDF Author: Jenifer Glynn
Publisher: Oxford University Press, USA
ISBN: 0199699623
Category : Biography & Autobiography
Languages : en
Pages : 187

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Book Description
A brief personal account by her sister, of Rosalind Franklin's family life.

Unraveling DNA

Unraveling DNA PDF Author: Maxim D. Frank-Kamenetskii
Publisher: Wiley
ISBN: 9780471188520
Category : Science
Languages : en
Pages : 216

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Book Description
... brilliant ... Yet anybody can understand it: it reads like a detective story.' John Maddox, Editor of Nature ' ... he skillfully imbues us with his joy and fascination with the living world, and the role of DNA in it.' Bruce M. Alberts, President of the National Academy of Sciences Unraveling DNA provides both laymen and scientist readers with a concise highly readable understanding of the structure, properties, and functions of the DNA molecule. The reader will find answers to all major questions about the biological, biotechnological, medical, physical, chemical, and mathematical aspects of DNA. In addition, the book includes an historical retrospective of past DNA research and forecasts future trends in the field. Written by an internationally acclaimed professor of biophysics as well as one of the world's leading authorities in DNA research, Unraveling DNA is designed to help professionals not specializing in molecular biology to understand the recent advances in this rapidly expanding field. The book is also especially useful to advanced high school students, junior college students, and university students interested in modern biology, medicine, physics, chemistry, and mathematics.

Unravelling the Double Helix

Unravelling the Double Helix PDF Author: Gareth Williams
Publisher: Weidenfeld & Nicolson
ISBN: 1474609384
Category : Science
Languages : en
Pages : 500

Get Book Here

Book Description
DNA. The double helix; the blueprint of life; and, during the early 1950s, a baffling enigma that could win a Nobel Prize. Everyone knows that James Watson and Francis Crick discovered the double helix. In fact, they clicked into place the last piece of a huge jigsaw puzzle that other researchers had assembled over decades. Researchers like Maurice Wilkins (the 'Third Man of DNA') and Rosalind Franklin, famously demonised by Watson. Not forgetting the 'lost heroes' who fought to prove that DNA is the stuff of genes, only to be airbrushed out of history. In Unravelling the Double Helix, Professor Gareth Williams sets the record straight. He tells the story of DNA in the round, from its discovery in pus-soaked bandages in 1868 to the aftermath of Watson's best-seller The Double Helix a century later. You don't need to be a scientist to enjoy this book. It's a page-turner that unfolds like a detective story, with suspense, false leads and treachery, and a fabulous cast of noble heroes and back-stabbing villains. But beware: some of the science is dreadful, and the heroes and villains may not be the ones you expect.

Principles of Nucleic Acid Structure

Principles of Nucleic Acid Structure PDF Author: Stephen Neidle
Publisher: Academic Press
ISBN: 0128196785
Category : Science
Languages : en
Pages : 456

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Book Description
Principles of Nucleic Acid Structure, Second Edition, provides the most complete and concise summary of underlying principles and approaches to studying nucleic acid structure, including discussions of X-ray crystallography, NMR, molecular modelling and databases. The book's focus is on a survey of structures that are especially important for biomedical research and pharmacological applications. This updated edition includes the latest advances relevant to recognition of DNA and RNA by small molecules and proteins, including sections on RNA folding, ribosome structure and antibiotic interactions, DNA quadruplexes, DNA and RNA protein complexes and short interfering RNA (siRNA).This reference is a must-have for those seeking an authoritative, comprehensive and up-to-date source on all aspects of nucleic acid structure, from basic first principles to details of recent research results. - Completely updated, with an expanded section on protein-nucleic acid interactions that reflects major increases in our knowledge - Defines technical terms for novices - Includes a complete list of resources, including relevant online databases and software, as well as useful websites

Why Us?

Why Us? PDF Author: James Le Fanu
Publisher: Vintage
ISBN: 1400030544
Category : Social Science
Languages : en
Pages : 322

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Book Description
In this daring treatise on the current state of scientific inquiry, James Le Fanu challenges the common assumption that further progress in genetic research and neuroscience must ultimately explain all there is to know about life and man’s place in the world. On the contrary, he argues, the most recent scientific findings point to an unbridgeable explanatory gap between the genes strung out along the Double Helix and the beauty and diversity of the living world—and between the electrical activity of the brain and the abundant creativity of the human mind. His exploration of these mysteries, and his analysis of where they might lead us in our thinking about the nature and purpose of human existence, form the impassioned and riveting heart of Why Us?

Molecular Engineering for Advanced Materials

Molecular Engineering for Advanced Materials PDF Author: J. Becher
Publisher: Springer Science & Business Media
ISBN: 940158575X
Category : Science
Languages : en
Pages : 383

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Book Description
An important aspect of molecular engineering is the `property directed' synthesis of large molecules and molecular assemblies. Synthetic expertise has advanced to a state which allows the assembly of supramolecules containing thousands of atoms using a `construction kit' of molecular building blocks. Expansion in the field is driven by the appearance of new building blocks and by an improved understanding of the rules for joining them in the design of nanometer-sized devices. Another aspect is the transition from supramolecules to materials. At present no single molecule (however large) has been demonstrated to function as a device, but this appears to be only a matter of time. In all of this research, which has a strongly multidisciplinary character, both existing and yet to be developed analytical techniques are and will remain indispensable. All this and more is discussed in Molecular Engineering for Advanced Materials, which provides a masterly and up to date summary of one of the most challenging research fields to emerge in recent time.

RNA, the Epicenter of Genetic Information

RNA, the Epicenter of Genetic Information PDF Author: John Mattick
Publisher: CRC Press
ISBN: 1000623114
Category : Science
Languages : en
Pages : 879

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Book Description
The origin story and emergence of molecular biology is muddled. The early triumphs in bacterial genetics and the complexity of animal and plant genomes complicate an intricate history. This book documents the many advances, as well as the prejudices and founder fallacies. It highlights the premature relegation of RNA to simply an intermediate between gene and protein, the underestimation of the amount of information required to program the development of multicellular organisms, and the dawning realization that RNA is the cornerstone of cell biology, development, brain function and probably evolution itself. Key personalities, their hubris as well as prescient predictions are richly illustrated with quotes, archival material, photographs, diagrams and references to bring the people, ideas and discoveries to life, from the conceptual cradles of molecular biology to the current revolution in the understanding of genetic information. Key Features Documents the confused early history of DNA, RNA and proteins - a transformative history of molecular biology like no other. Integrates the influences of biochemistry and genetics on the landscape of molecular biology. Chronicles the important discoveries, preconceptions and misconceptions that retarded or misdirected progress. Highlights major pioneers and contributors to molecular biology, with a focus on RNA and noncoding DNA. Summarizes the mounting evidence for the central roles of non-protein-coding RNA in cell and developmental biology. Provides a thought-provoking retrospective and forward-looking perspective for advanced students and professional researchers. The Open Access version of this book, available at www.taylorfrancis.com, has been made available under a Creative Commons Attribution-Non Commercial-No Derivatives 4.0 license.