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Author: Kakoli Bose
Publisher: Springer Nature
ISBN: 9813298162
Category : Medical
Languages : en
Pages : 587
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Book Description
Unravelling the intricate cell signalling networks and their significance in cancer poses major intellectual challenge. Keeping this in mind, the book aims at understanding the mechanism of action of different proteins and their complexes in the cancer signalling pathways. Hence, the proposed book that comprises 20 chapters provides a comprehensive introduction on cell signalling, its alterations in cancer, molecules that have been popular targets as well as the ones that are emerging as targets. In addition, it discusses different forms of therapy that are coming up for its treatment. Other than that, a major portion of the book is focused on studying different disciplines at the interface of biology and other areas of science that are being used to understand cancer biology in depth.
Author: Kakoli Bose
Publisher: Springer Nature
ISBN: 9813298162
Category : Medical
Languages : en
Pages : 587
Get Book Here
Book Description
Unravelling the intricate cell signalling networks and their significance in cancer poses major intellectual challenge. Keeping this in mind, the book aims at understanding the mechanism of action of different proteins and their complexes in the cancer signalling pathways. Hence, the proposed book that comprises 20 chapters provides a comprehensive introduction on cell signalling, its alterations in cancer, molecules that have been popular targets as well as the ones that are emerging as targets. In addition, it discusses different forms of therapy that are coming up for its treatment. Other than that, a major portion of the book is focused on studying different disciplines at the interface of biology and other areas of science that are being used to understand cancer biology in depth.
Author: Manish Kumar
Publisher: Springer Nature
ISBN: 9811559996
Category : Medical
Languages : en
Pages : 344
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Book Description
The book presents a comprehensive and up-to-date overview of phytochemicals as efficient cancer therapeutics. Over the last few decades there has been a paradigm shift from conventional cancer therapeutic approaches to alternative and complementary medicinal approaches especially using phytoconstituents from natural products. As such, the book provides an in-depth understanding of phytochemicals targeting diverse signaling pathways involved in cancer along with the evaluation of the cancer modulatory effects of phytochemicals. It also highlights the potential modulatory effect of single nucleotide polymorphisms (SNPs) on the cancer-associated cellular pathways and their interactions with the phytochemicals. Further, it analyzes the drug delivery methods, bioavailability of active components of botanicals, and toxicity of phytochemicals. Lastly, the book elucidates the 3D cell culture and animal models systems to analyze the beneficial effects of phytochemicals in cancer.
Author: Rebeca M. Mejias Estevez
Publisher: Frontiers Media SA
ISBN: 2832539122
Category : Science
Languages : en
Pages : 161
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Book Description
Author: Volkhard Helms
Publisher: John Wiley & Sons
ISBN: 3527830529
Category : Science
Languages : en
Pages : 436
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Book Description
Protein Interactions A fundamental guide to the burgeoning field of protein interactions From enzymes to transcription factors to cell membrane receptors, proteins are at the heart of biological cell function. Virtually all cellular processes are governed by their interactions, with one another, with cell bodies, with DNA, or with small molecules. The systematic study of these interactions is called Interactomics, and research within this new field promises to shape the future of molecular cell biology. Protein Interactions goes beyond any existing guide to protein interactions, presenting the first truly comprehensive overview of the field. Edited by two leading scholars in the field of protein bioinformatics, this book covers all known categories of protein interaction, stable as well as transient, as well as the effect of mutations and post-translational modifications on the interaction behavior. Protein Interactions readers will also find: Introductory chapters on protein structure, conformational dynamics, and protein-protein binding interfaces A data-driven approach incorporating machine learning and integrating experimental data into computational models An outlook on the current challenges in the field and suggestions for future research Protein Interactions will serve as a fundamental resource for novice researchers who want a systematic introduction to interactomics, as well as for experienced cell biologists and bioinformaticians who want to gain an edge in this exciting new field.
Author: Keun-Yeong Jeong
Publisher: BoD – Books on Demand
ISBN: 1789843995
Category : Medical
Languages : en
Pages : 108
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Book Description
A multidisciplinary understanding of the various processes leading to colorectal cancer progression is important for creating promising methods of therapy. Therefore it is necessary to scrutinize the progression of cancer and the therapeutic process through various academic theories. This book examines colorectal cancer - its prevention, pathogenesis, and treatment - through a multidisciplinary lens in an effort to advance understanding of the disease and improve therapeutic efficacy.
Author: Brigitte M. Pützer
Publisher: Frontiers Media SA
ISBN: 2889745805
Category : Science
Languages : en
Pages : 137
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Book Description
Author: Dr. Spineanu Eugenia
Publisher: Dr. Spineanu Eugenia
ISBN:
Category : Medical
Languages : en
Pages : 137
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Book Description
Discover 'Optimizing Well-Being in Hypopharyngeal Cancer,' a comprehensive guide tailored to patients and caregivers navigating the challenges of this condition. Written by medical experts, this treatise offers a holistic approach to managing hypopharyngeal cancer, providing invaluable insights into its medical intricacies, anatomy, risk factors, and pathogenesis. Readers will delve into the world of hypopharyngeal cancer, gaining a profound understanding of its genetic and epigenetic alterations, the role of oncogenes and tumor suppressors, and the intricate cell signaling pathways involved. Explore the latest research on biomarkers, metabolism, and immunological aspects, empowering you with knowledge to make informed decisions about your treatment journey. With chapters dedicated to surgical techniques, radiation therapy, chemotherapy, targeted therapies, immunotherapy, and palliative care, this treatise equips you with a comprehensive toolkit to combat hypopharyngeal cancer effectively. Dive into the world of cutting-edge treatments and emerging therapies, guided by the expertise of medical professionals. Additionally, this guide delves into complementary and alternative therapies, offering insights into their safe integration alongside conventional treatments. Explore the benefits of mind-body practices, social support, and coping strategies that enhance your emotional and psychological well-being. As you navigate your cancer journey, this treatise provides crucial guidance on survivorship, quality of life assessment, and holistic approaches to well-being. Empower yourself with knowledge, resilience, and the support needed to optimize your well-being in the face of hypopharyngeal cancer. 'Optimizing Well-Being in Hypopharyngeal Cancer' is your indispensable companion on the path to recovery and a resource you can trust. Start your journey to well-being today, and let this guide be your beacon of hope and healing.
Author: Wilson G. Pond
Publisher: CRC Press
ISBN: 1439897859
Category : Medical
Languages : en
Pages : 313
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Book Description
What constitutes animal welfare? With animals being used for companionship, service, research, food, fiber, and by-products, animal welfare is a topic of great interest and importance to society. As the world's population continues to increase, a major challenge for society is the maintenance of a strong and viable food system, which is linked to t
Author: National Research Council
Publisher: National Academies Press
ISBN: 0309109922
Category : Nature
Languages : en
Pages : 217
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Book Description
Advances in molecular biology and toxicology are paving the way for major improvements in the evaluation of the hazards posed by the large number of chemicals found at low levels in the environment. The National Research Council was asked by the U.S. Environmental Protection Agency to review the state of the science and create a far-reaching vision for the future of toxicity testing. The book finds that developing, improving, and validating new laboratory tools based on recent scientific advances could significantly improve our ability to understand the hazards and risks posed by chemicals. This new knowledge would lead to much more informed environmental regulations and dramatically reduce the need for animal testing because the new tests would be based on human cells and cell components. Substantial scientific efforts and resources will be required to leverage these new technologies to realize the vision, but the result will be a more efficient, informative and less costly system for assessing the hazards posed by industrial chemicals and pesticides.
Author: José Marín-García
Publisher: Academic Press
ISBN: 0124046428
Category : Medical
Languages : en
Pages : 935
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Book Description
In this second edition of Post-Genomic Cardiology, developing and new technologies such as translational genomics, next generation sequencing (NGS), bioinformatics, and systems biology in molecular cardiology are assessed in light of their therapeutic potential. As new methods of mutation screening emerge, both for the genome and for the "epigenome, comprehensive understanding of the many mutations that underlie cardiovascular diseases and adverse drug reactions is within our reach. This book, written by respected cardiologist José Marín-García, features discussion on the Hap-Map: the largest international effort to date aiming to define the differences between our individual genomes. This unique reference further reviews and investigates genome sequences from our evolutionary relatives that could help us decipher the signals of genes, and offers a comprehensive and critical evaluation of regulatory elements from the complicated network of the background DNA. - Offers updated discussion of cutting-edge molecular techniques including new genomic sequencing / NGS / Hap-Map / bioinformatics / systems biology approaches - Analyzes mitochondria dynamics and their role in cardiac dysfunction, up-to-date analysis of cardio-protection, and cardio-metabolic syndrome - Presents recent translational studies, gene therapy, transplantation of stem cells, and pharmacological treatments in CVDs
