Understanding Lung Acinar Micromechanics in Health and Disease: Linking Quantitative Imaging and Organ Scale Mechanics by Computational Modeling PDF Download
Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download Understanding Lung Acinar Micromechanics in Health and Disease: Linking Quantitative Imaging and Organ Scale Mechanics by Computational Modeling PDF full book. Access full book title Understanding Lung Acinar Micromechanics in Health and Disease: Linking Quantitative Imaging and Organ Scale Mechanics by Computational Modeling by Matthias Ochs. Download full books in PDF and EPUB format.
Author: Matthias Ochs
Publisher: Frontiers Media SA
ISBN: 2889665216
Category : Science
Languages : en
Pages : 220
Get Book Here
Book Description
Author: Matthias Ochs
Publisher: Frontiers Media SA
ISBN: 2889665216
Category : Science
Languages : en
Pages : 220
Get Book Here
Book Description
Author: Marc Poulin
Publisher: Springer Science & Business Media
ISBN: 038773693X
Category : Medical
Languages : en
Pages : 554
Get Book Here
Book Description
This volume comprises the proceedings of the 10th Oxford Conference held at Lake Louise, Alberta, Canada, in September, 2006. It contains the most up-to-date research in cardio-respiratory control and its content spans the disciplines of respiratory physiology, neurobiology, modeling, and biomedical engineering. The volume will be of interest to clinicians working with patients with breathing disorders.
Author: Daniel Eberli
Publisher: Springer
ISBN: 9783030442101
Category : Technology & Engineering
Languages : en
Pages : 0
Get Book Here
Book Description
The notion of being able to engineer complete organs has inspired an entire generation of researchers. While recent years have brought significant progress in regenerative medicine and tissue engineering, the immense challenges encountered when trying to engineer an entire organ have to be acknowledged. Despite a good understanding of cell phenotypes, cellular niches and cell-to-biomaterial interactions, the formation of tissues composed of multiple cells remains highly challenging. Only a step-by-step approach will allow the future production of a living tissue construct ready for implantation and to augment organ function. In this book, expert authors present the current state of this approach. It offers a concise overview and serves as a great starting point for anyone interested in the application of tissue engineering or regenerative medicine for organ engineering. Each chapter contains a short overview including physiological and pathological changes as well as the current clinical need. The potential cell sources and suitable biomaterials for each organ type are discussed and possibilities to produce organ-like structures are illustrated. The ultimate goal is for the generated small tissues to unfold their full potential in vivo and to serve as a native tissue equivalent. By integrating and evolving, these implants will form functional tissue in-vivo. This book discusses the desired outcome by focusing on well-defined functional readouts. Each chapter addresses the status of clinical translations and closes with the discussion of current bottlenecks and an outlook for the coming years. A successful regenerative medicine approach could solve organ shortage by providing biological substitutes for clinical use - clearly, this merits a collaborative effort.
Author: Julia Hoeng
Publisher: Academic Press
ISBN: 0128172037
Category : Technology & Engineering
Languages : en
Pages : 545
Get Book Here
Book Description
Organ-on-a-Chip: Engineered Microenvironments for Safety and Efficacy Testing contains chapters from world-leading researchers in the field of organ on a chip development and applications, with perspectives from life sciences, medicine, physiology and engineering. The book contains an overview of the field, with sections covering the major organ systems and currently available technologies, platforms and methods. As readers may also be interested in creating biochips, materials and engineering best practice, these topics are also described. Users will learn about the limitations of 2D in-vitro models and the available 3D in-vitro models (what benefits they offer and some examples). Finally, the MOC section shows how the organ on a chip technology can be adapted to improve the physiology of in-vitro models. - Includes case studies of other organs on a chip that have been developed and successfully used - Provides insights into functional microphysiological organ on a chip platforms for toxicity and efficacy testing, along with opportunities for translational medicine - Presented fields (PK/PD, physiology, medicine, safety) are given a definition followed by the challenges and potential of organs on a chip
Author: Ewald R. Weibel
Publisher: Harvard University Press
ISBN: 9780674657915
Category : Medical
Languages : en
Pages : 448
Get Book Here
Book Description
It is rare indeed for one book to be both a first-rate classroom text and a major contribution to scholarship. The Pathway for Oxygen is such a book, offering a new approach to respiratory physiology and morphology that quantitatively links the two. Professionalism in science has led to a compartmentalization of biology. Function is the domain of the physiologist, structure that of the morphologist, and they often operate with vastly disparate concepts and procedures. Yet the performance of the respiratory system depends both on structural and on functional properties that cannot be separated. The first chapter of The Pathway for Oxygen engages the student with the design and function of the vertebrate respiratory organs from a comparative viewpoint. The second chapter adds to that foundation the link between cell energetics and oxygen needs of the whole animal. With Chapter 3 the excitement begins--new ideas, fresh attacks on old problems, and a fuller account of the power of the quantitative approach Dr. Weibel has pioneered. The Pathway for Oxygen will be read eagerly by medical students, graduate students, advanced undergraduates in zoology--and by their professors.
Author: Ewald R. Weibel
Publisher: Academic Press
ISBN: 1483225798
Category : Computers
Languages : en
Pages : 164
Get Book Here
Book Description
Morphometry of the Human Lung considers the developments in understanding the quantitative anatomy of the lung, and in the correlation of anatomy with physiology. This book is composed of 11 chapters, and begins with an overview of a systematic approach to a quantitative morphologic analysis of the architecture of the human lung, followed by a presentation of general problems of methodology and the derivation of reliable dimensional models of this organ. The subsequent chapters describe the methods of preparation of tissues, methods of random sampling, and adaptation of methodologies from other fields of science. These topics are followed by discussions the mathematical formulations for the translation of the data into the desired geometric forms and a technique of counting. The final chapters look into the mode of distribution and geometric forms that should eventually facilitate mathematical and physical considerations regarding the function of the lungs. These chapters also consider the application of these quantitative methods to the study of pathologic specimens, providing a most timely renovation of morphologic pathology. This book will be of value to pulmonologists, physiologists, and researchers who are interested in lung morphometry.
Author: Claudia Mierke
Publisher: Iph001
ISBN: 9780750317511
Category : Science
Languages : en
Pages : 500
Get Book Here
Book Description
This revised second edition is improved linguistically with multiple increases of the number of figures and the inclusion of several novel chapters such as actin filaments during matrix invasion, microtubuli during migration and matrix invasion, nuclear deformability during migration and matrix invasion, and the active role of the tumor stroma in regulating cell invasion.
Author: Peter Fratzl
Publisher: Springer Science & Business Media
ISBN: 0387739068
Category : Technology & Engineering
Languages : en
Pages : 516
Get Book Here
Book Description
Not only does this book provide a comprehensive review of current research advances in collagen structure and mechanics, it also explores this biological macromolecule’s many applications in biomaterials and tissue engineering. Readers gain an understanding of the structure and mechanical behavior of type I collagen and collagen-based tissues in vertebrates across all length scales, from the molecular (nano) to the organ (macro) level.
Author: Ewald R. Weibel
Publisher: Harvard University Press
ISBN: 9780674000681
Category : Science
Languages : en
Pages : 288
Get Book Here
Book Description
Are animals designed economically? The theory of symmorphosis predicts that the size of the parts in a system must be matched to the overall functional demand. Weibel shows how animals as different as shrews, pronghorns, dogs, goats--even humans--all develop from essentially the same blueprint by variation of design.
Author: Ewald R. Weibel
Publisher:
ISBN:
Category : Science
Languages : en
Pages : 448
Get Book Here
Book Description
