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Author: World Health Organization
Publisher: World Health Organization
ISBN: 9241563761
Category : History
Languages : en
Pages : 175
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Book Description
Assessment of human exposure to chemicals is a critical input to risk assessment and ultimately to decisions about control of chemicals. This two-part publication aims to improve the quality of information available to decision-makers and its communication. Part one sets out ten principles for characterizing and communicating uncertainty in exposure assessment. A tiered approach to the evaluation of uncertainties using both qualitative (simple) and quantitative (more complex) methods is described. Different sources of uncertainty are identified and guidance is provided on selecting the appropriate approach to uncertainty analysis as dictated by the objectives of the assessment and information needs of decision-makers and stakeholders. Part two addresses the quality of data used in exposure assessment and sets out four basic hallmarks of data quality - appropriateness accuracy integrity and transparency. These hallmarks provides a common vocabulary and set of qualitative criteria for use in the design evaluation and use of exposure assessments to support decisions. This publication is intended exposure assessors risk assessors and decision-makers.
Author: World Health Organization
Publisher: World Health Organization
ISBN: 9241563761
Category : History
Languages : en
Pages : 175
Get Book Here
Book Description
Assessment of human exposure to chemicals is a critical input to risk assessment and ultimately to decisions about control of chemicals. This two-part publication aims to improve the quality of information available to decision-makers and its communication. Part one sets out ten principles for characterizing and communicating uncertainty in exposure assessment. A tiered approach to the evaluation of uncertainties using both qualitative (simple) and quantitative (more complex) methods is described. Different sources of uncertainty are identified and guidance is provided on selecting the appropriate approach to uncertainty analysis as dictated by the objectives of the assessment and information needs of decision-makers and stakeholders. Part two addresses the quality of data used in exposure assessment and sets out four basic hallmarks of data quality - appropriateness accuracy integrity and transparency. These hallmarks provides a common vocabulary and set of qualitative criteria for use in the design evaluation and use of exposure assessments to support decisions. This publication is intended exposure assessors risk assessors and decision-makers.
Author: WHO
Publisher: World Health Organization
ISBN: 9789241563765
Category : History
Languages : en
Pages : 171
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Book Description
Assessment of human exposure to chemicals is a critical input to risk assessment and ultimately to decisions about control of chemicals. This two-part publication aims to improve the quality of information available to decision-makers and its communication. Part one sets out ten principles for characterizing and communicating uncertainty in exposure assessment. A tiered approach to the evaluation of uncertainties using both qualitative (simple) and quantitative (more complex) methods is described. Different sources of uncertainty are identified and guidance is provided on selecting the appropriate approach to uncertainty analysis as dictated by the objectives of the assessment and information needs of decision-makers and stakeholders. Part two addresses the quality of data used in exposure assessment and sets out four basic hallmarks of data quality - appropriateness accuracy integrity and transparency. These hallmarks provides a common vocabulary and set of qualitative criteria for use in the design evaluation and use of exposure assessments to support decisions. This publication is intended exposure assessors risk assessors and decision-makers.
Author: International Programme on Chemical Safety
Publisher:
ISBN:
Category :
Languages : en
Pages : 158
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Book Description
Author: A. John Bailer
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 400
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Book Description
This volume presents papers devoted to improving the understanding of the sources, and magnitude of uncertainty, in the risk assessment process for enviromental and occupational hazards. They discuss the means of reducing this uncertainty, and describe and characterize how to express it.
Author: Organizzazione mondiale della sanitÃ
Publisher:
ISBN:
Category :
Languages : en
Pages : 158
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Book Description
Author: Kenneth Bogen
Publisher: Dissertations-G
ISBN:
Category : Medical
Languages : en
Pages : 232
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Book Description
Author: United States. Indoor Air Quality/Total Human Exposure Committee
Publisher:
ISBN:
Category : Environmental health
Languages : en
Pages : 44
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Book Description
Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309453518
Category : Nature
Languages : en
Pages : 201
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Book Description
Over the last decade, several large-scale United States and international programs have been initiated to incorporate advances in molecular and cellular biology, -omics technologies, analytical methods, bioinformatics, and computational tools and methods into the field of toxicology. Similar efforts are being pursued in the field of exposure science with the goals of obtaining more accurate and complete exposure data on individuals and populations for thousands of chemicals over the lifespan; predicting exposures from use data and chemical-property information; and translating exposures between test systems and humans. Using 21st Century Science to Improve Risk-Related Evaluations makes recommendations for integrating new scientific approaches into risk-based evaluations. This study considers the scientific advances that have occurred following the publication of the NRC reports Toxicity Testing in the 21st Century: A Vision and a Strategy and Exposure Science in the 21st Century: A Vision and a Strategy. Given the various ongoing lines of investigation and new data streams that have emerged, this publication proposes how best to integrate and use the emerging results in evaluating chemical risk. Using 21st Century Science to Improve Risk-Related Evaluations considers whether a new paradigm is needed for data validation, how to integrate the divergent data streams, how uncertainty might need to be characterized, and how best to communicate the new approaches so that they are understandable to various stakeholders.
Author: Kenneth Bogen
Publisher:
ISBN:
Category :
Languages : en
Pages : 416
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Book Description
Author: Alison C. Cullen
Publisher: Springer Science & Business
ISBN: 9780306459573
Category : Medical
Languages : en
Pages : 294
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Book Description
In this text, experts provide a complete sourcebook on methods for addressing variability and uncertainty in exposure analysis.
