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Author:
Publisher: Elsevier
ISBN: 0080862039
Category : Medical
Languages : en
Pages : 697
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Book Description
Transplantation into the Mammalian CNS
Author: Don M. Gash
Publisher: Elsevier
ISBN: 0444810129
Category : Medical
Languages : en
Pages : 697
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Book Description
Transplantation into the Mammalian CNS presents a comprehensive critical overview of recent advances of basic and clinical research in neural transplantation. Special emphasis is devoted to the emerging studies on the use of clinical grafts for the treatment of parkinsonism, the extension of this technology to additional models of neurological deficits, the immunobiology of neural implants, the exploration of trophic factors, and other new directions in the field of transplantation. Due to the extensive list of contents, only content headings are given. Full details can be obtained from the Publisher upon request.
Author: Anders Björklund
Publisher: Elsevier Publishing Company
ISBN:
Category : Medical
Languages : en
Pages : 746
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Book Description
Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 52
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Book Description
Author: William J. Freed
Publisher: MIT Press
ISBN: 9780262062084
Category : Central nervous system
Languages : en
Pages : 590
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Book Description
After providing basic background on transplantation, brain structure, and development, the book discusses Parkinson's disease, the use of transplants to influence localized brain functions, circuit reconstruction, and genetic engineering and other future technologies.
Author: John R. Sladek
Publisher:
ISBN: 9781468446869
Category :
Languages : en
Pages : 488
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Book Description
Author: John R. Sladek
Publisher: Springer Science & Business Media
ISBN: 1468446851
Category : Medical
Languages : en
Pages : 468
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Book Description
The story of mammalian neural transplantation really begins eighty-one years ago. In Chicago in December of 1903, a 34-year-old physician, Elizabeth Hopkins Dunn, working as a research assistant in neurology, initiated a series of experiments to examine the ability of neonatal rat cerebral tissue to survive transplantation into the brain of matched littermates. Out of 46 attempts, four clearly successful grafts were identified. The publication of Dunn's results in 1917, the first credible report to demonstrate the feasibility of mammalian CNS transplants, generated little interest. In fact, the next significant experiment in this field did not appear until 1930. The field continued to grow slowly and quietly as investigators gradually realized the value of neural trans plantation to study problems of development and plasticity in the mammalian nervous system. With the discovery in 1979 that grafted neurons were capable of appropriate and functional interactions with the host brain, interest in neural transplantation esca lated sharply. The extraordinary opportunities created by using functional neural trans plants in investigating basic issues in neurobiology, as well as the clinical implications, excited both scientists and the public. The popularity of neural transplantation has been growing rapidly in the past five years and shows no signs of abating. The present volume was designed to meet two needs created by the rapid growth of this subdiscipline of neurobiology. The first was to provide a thorough review of the experimental foundations of neural transplantation.
Author: Stephen B. Dunnett
Publisher: Lippincott Williams & Wilkins
ISBN:
Category : Medical
Languages : en
Pages : 616
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Book Description
Author: Godwin S. Okoye
Publisher:
ISBN:
Category :
Languages : en
Pages : 202
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Book Description
Author:
Publisher: Elsevier
ISBN: 0080862039
Category : Medical
Languages : en
Pages : 697
Get Book Here
Book Description
Transplantation into the Mammalian CNS
Author: Dorothy E. Oorschot
Publisher: Springer Science & Business Media
ISBN: 3642751083
Category : Medical
Languages : en
Pages : 196
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Book Description
This state-of-the-art review links the experimental data into a cohesive and critical account of CNS regeneration. Research findings are discussed in terms of their relevance to one (or more) of thirteen hypotheses concerned with regeneration in the mammalian CNS. Research findings reviewed include: regeneration in developing mammals and in submammalian vertebrates, the use of transplants and/or pharmacological treatments, in vitro studies on neurotrophic and neurite promoting factors and their potential relevance to CNS regeneration in vivo, and in vitro studies on the types of glial cells that may be responsible for enhancing or suppressing axonal re-growth.
