Transcriptional Corepressors: Mediators of Eukaryotic Gene Repression PDF Download
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Author: Martin L. Privalsky
Publisher: Springer Science & Business Media
ISBN: 3662105950
Category : Medical
Languages : en
Pages : 202
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Book Description
Corepressors are newly discovered assemblies of proteins that play essential roles in eukaryotic gene regulation. Recent discoveries about corepressors have provided new insights into the molecular basis of gene regulation, and have established surprising connections between the mechanisms of action of a wide variety of transcriptional regulators. The reviews in this volume critically discuss the nature, mechanisms of action, and physiological roles of corepressors in a diverse assortment of biological systems. Both basic and clinical investigators will be able to find relevant information. The comprehensive nature of the compilation, and the breadth of the reviews, are intended to provide the reader with an excellent introduction to the newly emergent and rapidly-growing field of corepressor research. A valuable and detailed reference guide.
Author: Martin L. Privalsky
Publisher: Springer Science & Business Media
ISBN: 3662105950
Category : Medical
Languages : en
Pages : 202
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Book Description
Corepressors are newly discovered assemblies of proteins that play essential roles in eukaryotic gene regulation. Recent discoveries about corepressors have provided new insights into the molecular basis of gene regulation, and have established surprising connections between the mechanisms of action of a wide variety of transcriptional regulators. The reviews in this volume critically discuss the nature, mechanisms of action, and physiological roles of corepressors in a diverse assortment of biological systems. Both basic and clinical investigators will be able to find relevant information. The comprehensive nature of the compilation, and the breadth of the reviews, are intended to provide the reader with an excellent introduction to the newly emergent and rapidly-growing field of corepressor research. A valuable and detailed reference guide.
Author: Martin L. Privalsky
Publisher:
ISBN: 9783662105962
Category :
Languages : en
Pages : 212
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Book Description
Author: David S. Latchman
Publisher: Academic Press
ISBN: 0080531261
Category : Medical
Languages : en
Pages : 391
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Book Description
Now in two-colour throughout, the fourth edition of Eukaryotic Transcription Factors has been completely rewritten and restructured to take into account the tremendous advances in our understanding of transcription factors and the mechanisms by which they act. Considerable emphasis has been given to the interaction between transcription factors and chromatin structure. Also included is an entirely new section on the mediator complex and expansion of the space devoted to co-activators and co-repressors.This book is essential reading for all those who wish to understand the impact of molecular biology on medicine, whatever their speciality. Major families of eukaryotic transcription factors described Mechanisms of gene activation and repression analysed Structure-function relationships indicated Interaction between transcription factors and chromatin structure described Roles in inducible and cell type-specific gene expression Roles in development, differentiation and human diseases including cancer Methods of study in vitro and in vivo
Author: Michael F. Carey
Publisher: CSHL Press
ISBN: 9780879696351
Category : Medical
Languages : en
Pages : 684
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Book Description
In the genome era, the analysis of gene expression has become a critical requirement in many laboratories. But there has been no comprehensive source of strategic, conceptual, and technical information to guide this often complex task. Transcriptional Regulation in Eukaryotes answers that need. Written by two experienced investigators, Michael Carey and Stephen Smale at the UCLA School of Medicine, and based in part on the Gene Expression course taught at Cold Spring Harbor Laboratory, this book directly addresses all the concerns of a laboratory studying the regulation of a newly isolated gene and the biochemistry of a new transcription factor. This important and unique book is essential reading for anyone pursuing the analysis of gene expression in model systems or disease states.
Author: Athanasios Papavassiliou
Publisher: International Thomson Publishing Services
ISBN:
Category : Cellular signal transduction
Languages : en
Pages : 388
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Book Description
Author: David S. Latchman
Publisher: Nelson Thornes
ISBN:
Category : Science
Languages : en
Pages : 360
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Book Description
The previous editions of Gene Regulation have helped students in biological science and medicine gain a full understanding of the issues of gene regulation. In this edition, new material reflects the progress that has been made in the understanding of gene regulation. The most significant change is the addition of an extra chapter describing the basic processes by which DNA is converted in RNA and then into protein. This important new chapter makes this edition complete as a textbook on gene expression and its regulation.
Author: Edgar Wingender
Publisher: Wiley-Blackwell
ISBN:
Category : Science
Languages : en
Pages : 452
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Book Description
A much-needed guide through the overwhelming amount of literature in the field. Comprehensive and detailed, this book combines background information with the most recentinsights. It introduces current concepts, emphasizing the transcriptional control of genetic information. Moreover, it links data on the structure of regulatory proteins with basic cellular processes. Both advanced students and experts will find answers to such intriguing questions as: - How are programs of specific gene repertoires activated and controlled? - Which genes drive and control morphogenesis? - Which genes govern tissue-specific tasks? - How do hormones control gene expression in coordinating the activities of different tissues? An abundant number of clearly presented glossary terms facilitates understanding of the biological background. Speacial feature: over 2200 (!) literature references.
Author: Gerald M. Kolodny
Publisher: CRC Press
ISBN: 1351088823
Category : Medical
Languages : en
Pages : 239
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Book Description
The cause of cancer and its many manifestations is at present unknown. Since many of its manifestations, including is control of cell division, appear to represent abnormal patterns of gene expression, studies of the regulation of gene expression nwill provide important insights in the understanding and treatment of cancer. This volume attempts to present some of the recent work on regulation of gene expression in eukaryotic cells.
Author:
Publisher:
ISBN:
Category : Cells
Languages : en
Pages : 248
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Book Description
Author: Stephen Goodbourn
Publisher: Oxford University Press
ISBN: 9780199634873
Category : Eukaryotic Cells.
Languages : en
Pages : 292
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Book Description
The field of eukaryotic gene transcription - conversion of genetic information into RNA molecules in the nuclei of cells - is a fast-moving and important area of molecular biology. This book reviews current developments in this area, giving a comprehensive but focused account. Topics covered include positive and negative regulation of RNA polymerase II transcription, histones and transcription control, regulation of Rel transcription complexes, multifactorial and combinatorial models for specific transcriptional regulation, the function of homeodomain proteins in Drosophila development, and transcriptional regulation of skeletal myogenesis.
