Transacting Functions of Human Retroviruses PDF Download
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Author: Irvin S.Y. Chen
Publisher: Springer Science & Business Media
ISBN: 3642789293
Category : Medical
Languages : en
Pages : 248
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Book Description
The coding domains of simple retrovirus genomes direct the synthesis of virion proteins. Complex retroviral genomes generate in addition to virion proteins regulatory transacting proteins that are translated from multiple spliced messenger RNAs and fulfill important functions in the virus life cycle. All human retroviruses have such complex genomes. The transacting proteins of these pathogens are attractive targets for therapeutic intervention because they are viral specific, are essential for efficient virus replication and may be mediators of viral pathogenicity. In summarizing the current knowledge on the regulatory transacting proteins of human retroviruses this volume makes an important contribution toward the control of virus disease.
Author: Irvin S.Y. Chen
Publisher: Springer Science & Business Media
ISBN: 3642789293
Category : Medical
Languages : en
Pages : 248
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Book Description
The coding domains of simple retrovirus genomes direct the synthesis of virion proteins. Complex retroviral genomes generate in addition to virion proteins regulatory transacting proteins that are translated from multiple spliced messenger RNAs and fulfill important functions in the virus life cycle. All human retroviruses have such complex genomes. The transacting proteins of these pathogens are attractive targets for therapeutic intervention because they are viral specific, are essential for efficient virus replication and may be mediators of viral pathogenicity. In summarizing the current knowledge on the regulatory transacting proteins of human retroviruses this volume makes an important contribution toward the control of virus disease.
Author: I. Wei Chen
Publisher:
ISBN:
Category :
Languages : en
Pages : 236
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Book Description
Author:
Publisher:
ISBN: 9780387579016
Category : Gene expression
Languages : en
Pages : 239
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Book Description
Author: Robert C. Gallo
Publisher: Elsevier
ISBN: 0080918328
Category : Science
Languages : en
Pages : 440
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Book Description
This book presents twenty-four tightly focused reviews on the biology, molecular biology, pathology, and epidemiology of the human retroviruses, particularly HIV and HTLV (Types I and II), as well as animal model systems (simian retroviruses, STLV and SIV, and mouse models).Editor Robert C. Gallo is recognized as a co-discoverer of the AIDS virus.
Author: B. Robert Franza
Publisher: CSHL Press
ISBN: 9780879693152
Category : Health & Fitness
Languages : en
Pages : 352
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Book Description
Author: Kuan-teh Jeang
Publisher: World Scientific
ISBN: 981446564X
Category : Science
Languages : en
Pages : 502
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Book Description
There are three major types of human retroviruses, namely HIV, HTLV, and endogenous human retroviruses. This book presents the latest findings on the replication of these human retroviruses. This book is unique in that there has been no comparable book that integrates the findings from the three known classes of human retroviruses. Other books have focused on one of the three classes of human retroviruses individually.An accomplished international team of contributing authors have combined their expertise to provide cutting-edge findings in this important field. The book will be a valuable reference for students, researchers and medical professionals.
Author: Hidesaburo Hanafusa
Publisher: Elsevier
ISBN: 0323160190
Category : Medical
Languages : en
Pages : 209
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Book Description
Retroviruses and Disease presents a relevant summary of the state of knowledge in both human nonhuman retroviruses. It highlights significant concepts regarding their commonalities and differences in terms of retroviral systems. A section of this book covers the pathogenic human retroviruses and focuses on two. These are HLTV-1 (the first human retrovirus that was isolated) and HIV (the cause of a potent immunological disorder). The life cycle of replication-competent retroviruses, including the murine leukemia viruses and its functions, is discussed in Chapters 1 and 2. The focus of the third chapter is the transformation of Rous sarcoma virus. Meanwhile, Chapter 4 discusses the multiple stages in avian leukosis virus-induced B cell lymphoma. Oncogenes, the molecular basis of human cancer, are also covered in this book. Another virus also discussed in this book is the human T cell leukemia virus. The book is a good reference for students, teachers, specialists, scientists, and researchers in microbiology.
Author: Elisa Vicenzi
Publisher: Humana
ISBN: 9781493962587
Category : Medical
Languages : en
Pages : 0
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Book Description
Human Retroviruses: Methods and Protocols collects key experimental protocols that have provided the basis of the major discoveries of the field. Split into five sections, this detailed volume covers mapping of the HIV life cycle, isolation, co-receptor use, and cell tropism of HIV-1, in vivo quantification of HIV-1, biological aspects of HIV-1, as well as HTLVs. Some articles explore “assay and function of accessory genes”, largely involving the interface between retroviral and host factors, the extracellular role of Tat and Tax, resembling the function of cytokines, and the biotechnological exploitation of HIV as lentiviral vector to carry foreign genes with therapeutic value. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Comprehensive and authoritative, Human Retroviruses: Methods and Protocols provides state-of-art methodological protocols from world leaders in human retrovirology, essential for any lab working this vital field.
Author: Reinhard Kurth
Publisher: Caister Academic Press Limited
ISBN: 9781904455554
Category : Science
Languages : en
Pages : 0
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Book Description
Leading scientists in the field review the genomics, molecular biology and pathogenesis of these important viruses, comprehensively covering all the recent advances.
Author: Sudhir Gupta
Publisher: Springer Science & Business Media
ISBN: 1489901914
Category : Medical
Languages : en
Pages : 618
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Book Description
Leading experts provide the only comprehensive book examining all aspects of immune response and immune-based treatments for HIV infection. Contributions, divided into three sections, discuss basic mechanisms, immunopathogenesis of HIV infection, and immune-based therapies. Researchers thoroughly review vaccine-including prospects of T cell vaccine-and gene therapy for HIV infection. Additional topics include organization of HIV genes, the role of co-receptors in signaling of lymphocytes, and biological response modifiers. This reference is designed for basic and clinical researchers, internists, pediatricians, infectious disease specialists, neuropathologists, oncologists, and rheumatologists.
