Towards a New 3Rs Era in Experimental Research

Towards a New 3Rs Era in Experimental Research PDF Author: Christopher R. Cederroth
Publisher: Frontiers Media SA
ISBN: 2832548342
Category : Medical
Languages : en
Pages : 478

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Book Description
With the persisting need of animal experimentation for fundamental and applied research, the relevance and importance of the 3Rs Principle cannot be ignored. The 3Rs Principle was put forward over 50 years ago, providing an essential framework for more humane animal experimentation in research. In this half-century the research landscape within which this principle is applied has dramatically changed and evolved, with ever more emerging venues to explore for 3Rs advancement and implementation.

Towards a New 3Rs Era in Experimental Research

Towards a New 3Rs Era in Experimental Research PDF Author: Christopher R. Cederroth
Publisher: Frontiers Media SA
ISBN: 2832548342
Category : Medical
Languages : en
Pages : 478

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Book Description
With the persisting need of animal experimentation for fundamental and applied research, the relevance and importance of the 3Rs Principle cannot be ignored. The 3Rs Principle was put forward over 50 years ago, providing an essential framework for more humane animal experimentation in research. In this half-century the research landscape within which this principle is applied has dramatically changed and evolved, with ever more emerging venues to explore for 3Rs advancement and implementation.

Animal Experimentation: Working Towards a Paradigm Change

Animal Experimentation: Working Towards a Paradigm Change PDF Author: Kathrin Herrmann
Publisher: BRILL
ISBN: 9004391193
Category : Philosophy
Languages : en
Pages : 749

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Book Description
Animal experimentation has been one of the most controversial areas of animal use, mainly due to the intentional harms inflicted upon animals for the sake of hoped-for benefits in humans. Despite this rationale for continued animal experimentation, shortcomings of this practice have become increasingly more apparent and well-documented. However, these limitations are not yet widely known or appreciated, and there is a danger that they may simply be ignored. The 51 experts who have contributed to Animal Experimentation: Working Towards a Paradigm Change critically review current animal use in science, present new and innovative non-animal approaches to address urgent scientific questions, and offer a roadmap towards an animal-free world of science.

The Principles of Humane Experimental Technique

The Principles of Humane Experimental Technique PDF Author: William Moy Stratton Russell
Publisher: Hyperion Books
ISBN:
Category : Nature
Languages : en
Pages : 256

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Book Description


International Animal Research Regulations

International Animal Research Regulations PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 0309252113
Category : Science
Languages : en
Pages : 102

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Book Description
Animals are widely used in neuroscience research to explore biological mechanisms of nervous system function, to identify the genetic basis of disease states, and to provide models of human disorders and diseases for the development of new treatments. To ensure the humane care and use of animals, numerous laws, policies, and regulations are in place governing the use of animals in research, and certain animal regulations have implications specific to neuroscience research. To consider animal research regulations from a global perspective, the IOM Forum on Neuroscience and Nervous System Disorders, in collaboration with the National Research Council and the Institute for Laboratory Animal Research, held a workshop in Buckinghamshire, UK, July 26-27, 2011. The workshop brought together neuroscientists, legal scholars, administrators, and other key stakeholders to discuss current and emerging trends in animal regulations as they apply to the neurosciences. This document summarizes the workshop.

The UFAW Handbook on the Care and Management of Laboratory and Other Research Animals

The UFAW Handbook on the Care and Management of Laboratory and Other Research Animals PDF Author: Robert C. Hubrecht
Publisher: John Wiley & Sons
ISBN: 1444318780
Category : Medical
Languages : en
Pages : 848

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Book Description
The seminal reference on the care of laboratory and captiveanimals, The UFAW Handbook on the Care and Management ofLaboratory and Other Research Animals is a must-have for anyoneworking in this field. The UFAW Handbook has been thedefinitive text since 1947. Written for an international audience,it contains contributions from experts from around the world. The book focuses on best practice principles throughout, providingcomprehensive coverage, with all chapters being peer reviewed byanonymous referees. As well as addressing the husbandry oflaboratory animals, the content is also of great value to zoos andaquaria. Changes for the eighth edition: Revised and updated to reflect developments since publicationof the previous edition. New chapters on areas of growing concern, including: the 3Rs;phenotyping; statistics and experimental design; welfareassessment; legislation; training of people caring for lab animals;and euthanasia. All material combined into one volume for ease ofreference. This book is published on behalf of UFAW (The UniversitiesFederation for Animal Welfare), with whom we also publish theUFAW/Wiley-Blackwell Animal Welfare Book Series. This majorseries of books provides an authoritative source ofinformation on worldwide developments, current thinking and bestpractice in the field of animal welfare science and technology. Fordetails of all of the titles in the series see ahref="http://www.wiley.com/go/ufaw"www.wiley.com/go/ufaw/a.

Management of Animal Care and Use Programs in Research, Education, and Testing

Management of Animal Care and Use Programs in Research, Education, and Testing PDF Author: Robert H. Weichbrod
Publisher: CRC Press
ISBN: 1498748457
Category : Medical
Languages : en
Pages : 917

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Book Description
AAP Prose Award Finalist 2018/19 Management of Animal Care and Use Programs in Research, Education, and Testing, Second Edition is the extensively expanded revision of the popular Management of Laboratory Animal Care and Use Programs book published earlier this century. Following in the footsteps of the first edition, this revision serves as a first line management resource, providing for strong advocacy for advancing quality animal welfare and science worldwide, and continues as a valuable seminal reference for those engaged in all types of programs involving animal care and use. The new edition has more than doubled the number of chapters in the original volume to present a more comprehensive overview of the current breadth and depth of the field with applicability to an international audience. Readers are provided with the latest information and resource and reference material from authors who are noted experts in their field. The book: - Emphasizes the importance of developing a collaborative culture of care within an animal care and use program and provides information about how behavioral management through animal training can play an integral role in a veterinary health program - Provides a new section on Environment and Housing, containing chapters that focus on management considerations of housing and enrichment delineated by species - Expands coverage of regulatory oversight and compliance, assessment, and assurance issues and processes, including a greater discussion of globalization and harmonizing cultural and regulatory issues - Includes more in-depth treatment throughout the book of critical topics in program management, physical plant, animal health, and husbandry. Biomedical research using animals requires administrators and managers who are knowledgeable and highly skilled. They must adapt to the complexity of rapidly-changing technologies, balance research goals with a thorough understanding of regulatory requirements and guidelines, and know how to work with a multi-generational, multi-cultural workforce. This book is the ideal resource for these professionals. It also serves as an indispensable resource text for certification exams and credentialing boards for a multitude of professional societies Co-publishers on the second edition are: ACLAM (American College of Laboratory Animal Medicine); ECLAM (European College of Laboratory Animal Medicine); IACLAM (International Colleges of Laboratory Animal Medicine); JCLAM (Japanese College of Laboratory Animal Medicine); KCLAM (Korean College of Laboratory Animal Medicine); CALAS (Canadian Association of Laboratory Animal Medicine); LAMA (Laboratory Animal Management Association); and IAT (Institute of Animal Technology).

The International Encyclopedia of Primatology, 3 Volume Set

The International Encyclopedia of Primatology, 3 Volume Set PDF Author: Agustín Fuentes
Publisher: John Wiley & Sons
ISBN: 0470673370
Category : Social Science
Languages : en
Pages : 1596

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Book Description
The International Encyclopedia of Primatology represents the first comprehensive encyclopedic reference focusing on the behaviour, biology, ecology, evolution, genetics, and taxonomy of human and non-human primates. Represents the first comprehensive encyclopedic reference relating to primatology Features more than 450 entries covering topics ranging from the taxonomy, history, behaviour, ecology, captive management and diseases of primates to their use in research, cognition, conservation, and representations in literature Includes coverage of the basic scientific concepts that underlie each topic, along with the latest advances in the field Highly accessible to undergraduate and graduate students in primatology, anthropology, and the medical, biological and zoological sciences Essential reference for academics, researchers and commercial and conservation organizations This work is also available as an online resource at www.encyclopediaofprimatology.com

Public Health Service Policy on Humane Care and Use of Laboratory Animals

Public Health Service Policy on Humane Care and Use of Laboratory Animals PDF Author: National Institutes of Health (U.S.). Office for Protection from Research Risks
Publisher:
ISBN:
Category : Animal experimentation
Languages : en
Pages : 40

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Book Description


Reducing, Refining and Replacing the Use of Animals in Toxicity Testing

Reducing, Refining and Replacing the Use of Animals in Toxicity Testing PDF Author: David G. Allen
Publisher: Royal Society of Chemistry
ISBN: 1849736529
Category : Medical
Languages : en
Pages : 386

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Book Description
This thought-provoking book describes the ever-expanding "toolbox" of methods now available to reduce, refine, or replace animal usage in toxicity testing.

Toxicity Testing in the 21st Century

Toxicity Testing in the 21st Century PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 0309151732
Category : Nature
Languages : en
Pages : 217

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Book Description
Advances in molecular biology and toxicology are paving the way for major improvements in the evaluation of the hazards posed by the large number of chemicals found at low levels in the environment. The National Research Council was asked by the U.S. Environmental Protection Agency to review the state of the science and create a far-reaching vision for the future of toxicity testing. The book finds that developing, improving, and validating new laboratory tools based on recent scientific advances could significantly improve our ability to understand the hazards and risks posed by chemicals. This new knowledge would lead to much more informed environmental regulations and dramatically reduce the need for animal testing because the new tests would be based on human cells and cell components. Substantial scientific efforts and resources will be required to leverage these new technologies to realize the vision, but the result will be a more efficient, informative and less costly system for assessing the hazards posed by industrial chemicals and pesticides.