Time Domains of Hypoxia Adaptation: Evolutionary Insights and Applications

Time Domains of Hypoxia Adaptation: Evolutionary Insights and Applications PDF Author: Tatum S. Simonson
Publisher: Frontiers Media SA
ISBN: 2889718468
Category : Science
Languages : en
Pages : 289

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Time Domains of Hypoxia Adaptation: Evolutionary Insights and Applications

Time Domains of Hypoxia Adaptation: Evolutionary Insights and Applications PDF Author: Tatum S. Simonson
Publisher: Frontiers Media SA
ISBN: 2889718468
Category : Science
Languages : en
Pages : 289

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Book Description


Time domains of hypoxia adaptation: Evolutionary insights and applications, volume II

Time domains of hypoxia adaptation: Evolutionary insights and applications, volume II PDF Author: Tatum S. Simonson
Publisher: Frontiers Media SA
ISBN: 2832527930
Category : Science
Languages : en
Pages : 161

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The Red Cell Life-Cycle From Erythropoiesis to Clearance

The Red Cell Life-Cycle From Erythropoiesis to Clearance PDF Author: Lars Kaestner
Publisher: Frontiers Media SA
ISBN: 2889457028
Category :
Languages : en
Pages : 238

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Book Description
The eBook ‘The red cell life-cycle from erythropoiesis to clearance’ continues the discussion of questions like: What are the changes associated with red blood cell maturation, adulthood and senescence? What are the determinants of red blood cell life span and clearance? What are the mechanisms in control of red blood cell mass in healthy humans and patients with various forms of anaemia? Can red blood cells be 'trained' to provide the body with more oxygen during endurance exercises? What are the markers of circulating red blood cell senescence and in cells during storage and transfusion? And what can be learned from various species that developed advanced adaptations to maintain oxygen delivery under stress conditions such as exercising to the limit, diving or living in anaerobic aquatic habitats or at high altitude? Within the approximately 120 days (or 40 in a mouse, or 150-170 in a horse) life span of 'healthy' red blood cells, many cellular properties change leading to aged mixed cell populations in the circulation. Red blood cells seem to be genetically terminated by the time they become red blood cells and the contributions of this eBook increase the understanding of this process. There are surprisingly versatile remodeling processes happening during the red blood cell life span. Numerous disorders are associated with the premature onset of the 'ageing process' of red blood cells. Furthermore, in vitro ageing and/or modifications as well as the slowing down of the modifications is an important issue in transfusion medicine. Many of the molecular mechanisms behind such effects are elucidated in this eBook.

Respiratory Muscle Training

Respiratory Muscle Training PDF Author: Alison McConnell
Publisher: Elsevier Health Sciences
ISBN: 0702054550
Category : Medical
Languages : en
Pages : 403

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Book Description
Respiratory Muscle Training: theory and practice is the world’s first book to provide an "everything-you-need-to-know" guide to respiratory muscle training (RMT). Authored by an internationally-acclaimed expert, it is an evidence-based resource, built upon current scientific knowledge, as well as experience at the cutting-edge of respiratory training in a wide range of settings. The aim of the book is to give readers: 1) an introduction to respiratory physiology and exercise physiology, as well as training theory; 2) an understanding of how disease affects the respiratory muscles and the mechanics of breathing; 3) an insight into the disease-specific, evidence-based benefits of RMT; 4) advice on the application of RMT as a standalone treatment, and as part of a rehabilitation programme; and finally, 5) guidance on the application of functional training techniques to RMT. The book is divided into two parts – theory and practice. Part I provides readers with access to the theoretical building blocks that support practice. It explores the evidence base for RMT as well as the different methods of training respiratory muscles and their respective efficacy. Part II guides the reader through the practical implementation of the most widely validated form of RMT, namely inspiratory muscle resistance training. Finally, over 150 "Functional" RMT exercises are described, which incorporate a stability and/or postural challenge – and address specific movements that provoke dyspnoea. Respiratory Muscle Training: theory and practice is supported by a dedicated website (www.physiobreathe.com), which provides access to the latest information on RMT, as well as video clips of all exercises described in the book. Purchasers will also receive a three-month free trial of the Physiotec software platform (via www.physiotec.ca), which allows clinicians to create bespoke training programmes (including video clips) that can be printed or emailed to patients. Introductory overviews of respiratory and exercise physiology, as well as training theory Comprehensive, up-to-date review of respiratory muscle function, breathing mechanics and RMT Analysis of the interaction between disease and respiratory mechanics, as well as their independent and combined influence upon exercise tolerance Analysis of the rationale and application of RMT to over 20 clinical conditions, e.g., COPD, heart failure, obesity, mechanical ventilation Evidence-based guidance on the implementation of inspiratory muscle resistance training Over 150 functional exercises that incorporate a breathing challenge www.physiobreathe.com - access up-to-date information, video clips of exercises and a three-month free trial of Physiotec’s RMT exercise module (via www.physiotec.ca)

Oxygen Sensing

Oxygen Sensing PDF Author:
Publisher: Elsevier
ISBN: 0080497195
Category : Science
Languages : en
Pages : 867

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Book Description
The ability of cells to sense and respond to changes in oxygenation underlies a multitude of developmental, physiological, and pathological processes. This volume provides a comprehensive compendium of experimental approaches to the study of oxygen sensing in 48 chapters that are written by leaders in their fields.

Plant Responses to Hypoxia

Plant Responses to Hypoxia PDF Author: Elena Loreti
Publisher: MDPI
ISBN: 3036501487
Category : Science
Languages : en
Pages : 288

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Book Description
Molecular oxygen deficiency leads to altered cellular metabolism and can dramatically reduce crop productivity. Nearly all crops are negatively affected by a lack of oxygen (hypoxia) due to adverse environmental conditions such as excessive rain and soil waterlogging. Extensive efforts to fully understand how plants sense oxygen deficiency and their ability to respond using different strategies are crucial to increase hypoxia tolerance. Progress in our understanding has been significant in recent years. This topic certainly deserves more attention from the academic community; therefore, we have compiled a series of articles reflecting the advancements made thus far.

Mosaic Evolution of Subterranean Mammals

Mosaic Evolution of Subterranean Mammals PDF Author: Eviatar Nevo
Publisher: Oxford University Press, USA
ISBN: 9780198575726
Category : Burrowing animals
Languages : en
Pages : 0

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Book Description
Subterranean life exists within an extraordinary environment and has evolved among different groups of mammals all over the globe. With relatively constant temperature, few opportunities to meet organisms other than the immediate family, and a completely different sensory environment, the evolution of such life is fascinating. Locomotion, communication, food-finding, navigation, circadian rhythms, and indeed the whole of the animals' physiology may be specialized to cope with life underground. And from burrowing to blindness, magnetic communication to the weird bee-like eusociality of blind mole rats, specialization has been extreme and has led to speciation in a whole range of new contexts. That the subterranean way of life occurs in different species of mammals across the globe has provided scientists with one of nature's best studied global evolutionary demonstrations of adaptive radiation and speciation. The revolution in molecular biology that has occurred over the last ten years has massively expanded these horizons, allowing scientists to explore, map, and clone the genes underlying the basis of adaptation and speciation and translate their fascinating structural and functional evolution into genes and genomic language. This book draws together the burgeoning literature about all aspects of the biology of subterranean mammals. Beginning with their evolutionary history and the processes that led to the subterranean way of life, the author reviews ecology, behavior, and physiology within the context of the highly stressful subterranean context, considers the specialization that has evolved in response, and then compares the eleven families of extant subterranean mammals. The incredible circumstances surrounding subterranean mammals present a unique, global, 'natural experiment' in evolution that has implications throughout biology. As such, this broad survey will stand as an invaluable reference to evolutionary biologists, ecologists, and molecular biologists for years to come.

Hypoxia and Human Diseases

Hypoxia and Human Diseases PDF Author: Jing Zheng
Publisher: BoD – Books on Demand
ISBN: 9535128957
Category : Medical
Languages : en
Pages : 456

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Book Description
This book contains a total of 21 chapters, each of which was written by experts in the corresponding field. The objective of this book is to provide a comprehensive and updated overview of cellular and molecular mechanisms underlying hypoxia's impacts on human health, as well as current advances and future directions in the detection, recognition, and management of hypoxia-related disorders. This collection of articles provides a clear update in the area of hypoxia research for biomedical researchers, medical students, nurse practitioners, and practicing clinicians in the fields of high altitude biology, cardiovascular biology and medicine, tumor oncology, obstetrics, pediatrics, and orthodontics and for others who may be interested in hypoxia.

The Hadal Zone

The Hadal Zone PDF Author: Alan Jamieson
Publisher: Cambridge University Press
ISBN: 1316060721
Category : Science
Languages : en
Pages : 397

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Book Description
The hadal zone represents one of the last great frontiers in marine science, accounting for 45% of the total ocean depth range. Despite very little research effort since the 1950s, the last ten years has seen a renaissance in hadal exploration, almost certainly as a result of technological advances that have made this otherwise largely inaccessible frontier, a viable subject for research. Providing an overview of the geology involved in trench formation, the hydrography and food supply, this book details all that is currently known about organisms at hadal depths and linkages to the better known abyssal and bathyal depths. New insights on how, where and what really survives and thrives in the deepest biozone are provided, allowing this region to be considered when dealing with sustainability and conservation issues in the marine environment.

Gene Expression and Regulation in Mammalian Cells - Transcription Toward the Establishment of Novel Therapeutics

Gene Expression and Regulation in Mammalian Cells - Transcription Toward the Establishment of Novel Therapeutics PDF Author:
Publisher:
ISBN: 9789535138686
Category :
Languages : en
Pages :

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Book Description