Third International Radiopharmaceutical Dosimetry Symposium PDF Download
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Author: Evelyn E. Watson
Publisher:
ISBN:
Category : Radiation
Languages : en
Pages : 692
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Author: Evelyn E. Watson
Publisher:
ISBN:
Category : Radiation
Languages : en
Pages : 692
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Author: Audrey T. Schlafke-Stelson
Publisher:
ISBN:
Category : Radiation
Languages : en
Pages : 752
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Author: Mrinal K. Dewanjee
Publisher: Springer Science & Business Media
ISBN: 1461535085
Category : Medical
Languages : en
Pages : 627
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Book Description
Among the readily available -emitting radionuclides, the nuclides of iodine have the greatest versatility in labeling both the hydrophilic and the lipophilic compounds that are used in biology and medicine. Biologically important micrmolecules, semimacromolecules, and macromolecules have been identified which, after iodination, almost maintain the same molecular configuration and similar biologic specificity as those of the parent molecules. The multiple techniques for iodination and the clinical use of iodinated products have made possible the present status of the development of diagnostic nuclear medicine. 125r, with a half-life of 60 days, has a crucial role in competitive protein-binding studies. 131r is useful for measuring thyroid uptake, for the diagnosis of thyroid carcinoma and metastasis, and for therapy. 1nr , with a reasonably shorter half-life, is almost ideal for thyroid workup and for a few useful labeled radiopharmaceutical. Although ~c is used more widely in diagnostic procedures, the radionuclides of iodine will always have a major role in biology and medicine. A considerable amount of information is scattered in the literature regarding the chemistry of radioiodination and the mechanism of tracer localization in cells and tissues. Labeled peptides, proteins, and antibodies are extensively used for protein turnover studies, receptor binding and tumor imaging studies, and radioimmunoassay. The general trend in the use of tracers in clinical nuclear medicine has been an evolution from 3H, 14C, 11C, and 13 to 125 , 131 and 123r to ~c and 111rn.
Author: Knud Kristensen
Publisher: Springer Science & Business Media
ISBN: 9400967535
Category : Medical
Languages : en
Pages : 392
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Book Description
Safety and efficacy of radiopharmaceuticals are elements of great importance in nuclear medicine. Since the first meeting in 1965 in Oak Ridge with the title Radiopharmaceuticals tremendous developments have taken place. In 1965 the whole technetium-99m area was just in its very beginning. Safety and efficacy of the non-radioactive pharmaceuticals have attracted great attention during the last 10 years and so have similar aspects of radiopharmaceuticals during the later years. Regulatory agencies are extending their work also to the preparation of radiopharmaceuticals at hospitals and to requirements for registration of radiopharmaceuticals. In a fast developing field there might be tendencies to confrontation between interests and there have certainly been some tendencies to put undue restrictions on the use of radio pharmaceuticals due to the lack of understanding between the industry and the regulatory authorities and between regulatory authorities and hospitals. Much of this may have been due to lack of information and certainly is due to the lack of fundamental scientific knowledge in many radiopharmaceutical aspects. A fast and safe introduction of new radio pharmaceuticals and the proper handling of these requires a lot of development work, but also an understanding of how general principles from the non-radioactive drug field may be sensibly transformed into the radiopharmaceutical area. It may even require compromises between requirements for safety in different areas such as radiation protection and pharmaceutical aspects.
Author: United States. Center for Devices and Radiological Health
Publisher:
ISBN:
Category : Medical radiology
Languages : en
Pages : 258
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Author: Center for Devices and Radiological Health (U.S.). Publications Support Branch
Publisher:
ISBN:
Category : Medical radiology
Languages : en
Pages : 250
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Author: H. Zaidi
Publisher: CRC Press
ISBN: 1420033255
Category : Medical
Languages : en
Pages : 389
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Therapeutic Applications of Monte Carlo Calculations in Nuclear Medicine examines the applications of Monte Carlo (MC) calculations in therapeutic nuclear medicine, from basic principles to computer implementations of software packages and their applications in radiation dosimetry and treatment planning. With chapters written by recognized authorit
Author: Amin I. Kassis
Publisher: Washington, DC : The College
ISBN:
Category : Radiation dosimetry
Languages : en
Pages : 352
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Author: Center for Devices and Radiological Health (U.S.)
Publisher:
ISBN:
Category : Radiology
Languages : en
Pages : 274
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Author: United States. Department of Health and Human Services
Publisher:
ISBN:
Category : Government publications
Languages : en
Pages : 410
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