Clinical Evaluation of Psychotropic Drugs for Psychiatric Disorders PDF Download
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Author: World Health Organization
Publisher: Seattle ; Toronto : Hogrefe & Huber Publishers
ISBN: 9780889370630
Category : Medical
Languages : en
Pages : 202
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Book Description
Psychotropic medications have been dramatically successful over the since the 1950s, but severe problems remain. The World Health Organization (WHO) has a legal responsibility to review these drugs, estimate their benefit/risk ratio, help ensure their proper prescription and recommend which ones require international controls. This book utilizes the experience of the WHO to provide information about how such drugs should be evaluated, such as the planning, executing, monitoring, analyzing, interpreting and reporting involved with correctly making such evaluations. Subjects range from the evaluation of drugs from primary studies in healthy volunteers to the longitudinal study of drugs in routine use. Further chapters examine special issues in the evaluations of drug effects upon children and the elderly. There is also a section on study design and a final brief chapter on some transcultural issues.
Author: World Health Organization
Publisher: Seattle ; Toronto : Hogrefe & Huber Publishers
ISBN: 9780889370630
Category : Medical
Languages : en
Pages : 202
Get Book Here
Book Description
Psychotropic medications have been dramatically successful over the since the 1950s, but severe problems remain. The World Health Organization (WHO) has a legal responsibility to review these drugs, estimate their benefit/risk ratio, help ensure their proper prescription and recommend which ones require international controls. This book utilizes the experience of the WHO to provide information about how such drugs should be evaluated, such as the planning, executing, monitoring, analyzing, interpreting and reporting involved with correctly making such evaluations. Subjects range from the evaluation of drugs from primary studies in healthy volunteers to the longitudinal study of drugs in routine use. Further chapters examine special issues in the evaluations of drug effects upon children and the elderly. There is also a section on study design and a final brief chapter on some transcultural issues.
Author: O. Benkert
Publisher:
ISBN:
Category : Clinical trials
Languages : en
Pages : 216
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Book Description
Author: Robert F. Prien
Publisher: Raven Press (ID)
ISBN:
Category : Medical
Languages : en
Pages : 760
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Book Description
A source book in clinical methods for the understanding of psycho- pharmacologic agents and clinical evaluation of drugs in the treatment of mental disorder, produced in association with the National Institute of Mental health and the American College of Neuropsychopharmacology. The volume consists of three main sections. The first addresses the historical context of clinical psychopharmacologic research and guidelines and the decision process involved in drug development and evaluation. Section II addresses broad developments and issues for clinical methodology, providing guidance in research principles, study design and implementation, reporting of study findings, and ethical considerations involving drug evaluations. Section III provides methodologic developments and recommendations for research involving specific patient populations. Annotation copyright by Book News, Inc., Portland, OR
Author: Paul A. Nicholson
Publisher:
ISBN:
Category :
Languages : en
Pages : 106
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Book Description
Author: Andre F. Carvalho
Publisher: Oxford University Press
ISBN: 0198746636
Category : Medical
Languages : en
Pages : 385
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Book Description
An invaluable guide to psychiatric presentation, diagnosis and treatment in a primary care setting.
Author: Lynne E. Turner
Publisher:
ISBN:
Category : Developmentally disabled children
Languages : en
Pages : 118
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Book Description
Author: Joseph F. Goldberg, M.D., M.S.
Publisher: American Psychiatric Pub
ISBN: 1585624888
Category : Medical
Languages : en
Pages : 618
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Book Description
"This book has been divided into three main sections. Part I deals with global issues that bear on the assessment and formulation of possible adverse effects and with pertinent concepts related to basic pharmacology, physiology, and medical monitoring. The chapters in Part II present information organized by individual organ systems or specific medical circumstances rather than by drugs or drug classes. This approach seems to provide a logical and comprehensible format that allow readers to search out information as referenced by a particular side effect (and its varied potential causes) and to locate a discussion of practical management strategies. Part III focuses on summary recommendations covering all the material presented in the book and is followed by helpful appendixes on self-assessment questions and resources for practitioners. The book is meant to serve as a ready reference that simultaneously provides scientific and scholarly discussion of available treatment options and presents their scientific rationales."--page xx.
Author: S. Nassir Ghaemi
Publisher: CRC Press
ISBN: 020390902X
Category : Medical
Languages : en
Pages : 363
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Book Description
This practical reference examines the advantages and disadvantages of polypharmacy in psychiatry, and provides up-to-date clinical guidelines on the appropriate use of combinations of pharmacological therapy in major psychiatric disorders-including multidisciplinary approaches to treatment, such as social work and psychopharmacology, and an examina
Author: Kalyna Z. Bezchlibnyk-Butler
Publisher: Hogrefe & Huber Publishing
ISBN:
Category : Medical
Languages : en
Pages : 76
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Book Description
Includes bibliography, glossary, and an extensive index which cross-references generic and trade names. New editions are available on a subscription basis.
Author: Otto Benkert
Publisher: Springer Science & Business Media
ISBN: 3642753701
Category : Medical
Languages : en
Pages : 175
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Book Description
The idea of placebo-controlled drug trials and the advent of test statistics during the first part of this century were the major milestones in the establishment of a convincing methodology for demonstrating the efficacy of treatments. The first tricyclic and neuroleptic drugs were tested for their efficacy in psychiatric disorders along the lines of these methodological developments, but subsequent trials with psychotropic drugs did not adhere to these principles to the same extent because it became difficult to justify placebo-controlled trials once effective treatments had been established. Consequently, the second generation of an tidepressants and neuroleptics (since the early 1960s) were mainly tested, in Europe at least, in samples of patients using trials controlled by standard treatment only, and the methodological basis of these second generation trials became fragile, as will be demonstrated by several papers in this book. This development did not provoke much discussion until recently, when scientific and administrative interest in the methodology of the evaluation of psychotropic drugs increased substantially. A series of factors contribute to the growing interest in the standards of psychotropic drug trials: 1. The proportion of psychiatric patients resistant to treatment is growing; the efficacy of well-established forms of treatment therefore seems to be limited. 2. A series of psychotropic drugs were withdrawn from the market, mainly because they caused serious side effects. The efficacy and safety ofthese drugs had previously been demonstrated in drug trials, which raised the question whether the drug trials carried out were well-designed.
