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Author: Gary P. Pisano
Publisher: Harvard Business Press
ISBN: 9781591398400
Category : Business & Economics
Languages : en
Pages : 278
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Book Description
Why has the biotechnology industry failed to perform up to expectations? This book attempts to answer this question by providing a critique of the industry. It reveals the causes of biotech's problems and offers an analysis on how the industry works. It also provides prescriptions for companies, seeking ways to improve the industry's performance.
Author: Gary P. Pisano
Publisher: Harvard Business Press
ISBN: 9781591398400
Category : Business & Economics
Languages : en
Pages : 278
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Book Description
Why has the biotechnology industry failed to perform up to expectations? This book attempts to answer this question by providing a critique of the industry. It reveals the causes of biotech's problems and offers an analysis on how the industry works. It also provides prescriptions for companies, seeking ways to improve the industry's performance.
Author:
Publisher: DIANE Publishing
ISBN: 1428966668
Category :
Languages : en
Pages : 48
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Book Description
Author: Robert H. Carlson
Publisher: Harvard University Press
ISBN: 0674053621
Category : Science
Languages : en
Pages : 290
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Book Description
“Essential reading for anyone who wishes to understand the current state of biotechnology and the opportunities and dangers it may create.” —American Scientist Technology is a process and a body of knowledge as much as a collection of artifacts. Biology is no different—and we are just beginning to comprehend the challenges inherent in the next stage of biology as a human technology. It is this critical moment, with its wide-ranging implications, that Robert Carlson considers in Biology Is Technology. He offers a uniquely informed perspective on the endeavors that contribute to current progress in this area—the science of biological systems and the technology used to manipulate them. In a number of case studies, Carlson demonstrates that the development of new mathematical, computational, and laboratory tools will facilitate the engineering of biological artifacts—up to and including organisms and ecosystems. Exploring how this will happen, with reference to past technological advances, he explains how objects are constructed virtually, tested using sophisticated mathematical models, and finally constructed in the real world. Such rapid increases in the power, availability, and application of biotechnology raise obvious questions about who gets to use it, and to what end. Carlson’s thoughtful analysis offers rare insight into our choices about how to develop biological technologies and how these choices will determine the pace and effectiveness of innovation as a public good.
Author: Scott Dessain
Publisher: Academic Press
ISBN: 0128092092
Category : Medical
Languages : en
Pages : 277
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Book Description
Preserving the Promise: Improving the Culture of Biotech Investment critically examines why most biotech startups fail, as they emerge from universities into an ecosystem that inhibits rather than encourages innovation. This "Valley of Death" squanders our public investments in medical research and with them, the promise of longer and healthier lives. The authors explicate the Translation Gap faced by early stage biotech companies, the result of problematic technology transfer and investment practices, and provide specific prescriptions for improving translation of important discoveries into safe and effective therapies. In Preserving the Promise, Dessain and Fishman build on their collective experience as company founders, healthcare investor (Fishman) and physician/scientist (Dessain). The book offers a forward-looking, critical analysis of "conventional wisdom" that encumbers commercialization practices. It exposes the self-defeating habits of drug development in the Valley of Death, that waste money and extinguish innovative technologies through distorted financial incentives. - Explains why translation of biotech discovery into medicine succeeds so infrequently that it's been dubbed the Valley of Death - Uncovers specific decision-making strategies that more effectively align incentives, improving clinical and financial outcomes for investors, inventor/entrepreneurs, and patients - Examines the critical, early stages of commercialization, where technology transfer offices and Angels act as gatekeepers to development, and where tension between short-term financial and long-term clinical aspirations sinks important technologies - Deconstructs the forces driving biotech, recasts them in a proven conceptual framework, and offers practical guidance for making the system better
Author: Craig Holdrege
Publisher: University Press of Kentucky
ISBN: 0813138752
Category : Science
Languages : en
Pages : 272
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Book Description
In 2001 the Human Genome Project announced that it had successfully mapped the entire genetic content of human DNA. Scientists, politicians, theologians, and pundits speculated about what would follow, conjuring everything from nightmare scenarios of state-controlled eugenics to the hope of engineering disease-resistant newborns. As with debates surrounding stem-cell research, the seemingly endless possibilities of genetic engineering will continue to influence public opinion and policy into the foreseeable future. Beyond Biotechnology: The Barren Promise of Genetic Engineering distinguishes between the hype and reality of this technology and explains the nuanced and delicate relationship between science and nature. Authors Craig Holdrege and Steve Talbott evaluate the current state of genetic science and examine its potential applications, particularly in agriculture and medicine, as well as the possible dangers. The authors show how the popular view of genetics does not include an understanding of the ways in which genes actually work together in organisms. Simplistic and reductionist views of genes lead to unrealistic expectations and, ultimately, disappointment in the results that genetic engineering actually delivers. The authors explore new developments in genetics, from the discovery of "non-Darwinian" adaptative mutations in bacteria to evidence that suggests that organisms are far more than mere collections of genetically driven mechanisms. While examining these issues, the authors also answer vital questions that get to the essence of genetic interaction with human biology: Does DNA "manage" an organism any more than the organism manages its DNA? Should genetically engineered products be labeled as such? Do the methods of the genetic engineer resemble the centuries-old practices of animal husbandry? Written for lay readers, Beyond Biotechnology is an accessible introduction to the complicated issues of genetic engineering and its potential applications. In the unexplored space between nature and laboratory, a new science is waiting to emerge. Technology-based social and environmental solutions will remain tenuous and at risk of reversal as long as our culture is alienated from the plants and animals on which all life depends.
Author: Ramez Naam
Publisher: Broadway
ISBN: 9780767918435
Category : Genetic engineering
Languages : en
Pages : 0
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Book Description
What if you could be smarter, stronger, and have a better memory just by taking a pill? What if we could alter our genes to cure Alzheimer’s and Parkinson’s? What if we could halt or even reverse the human aging process? What if we could communicate with each othersimply by thinking about it? These questions were once the stuff of science fiction. Today, advances in biotechnology have shown that they’re plausible, even likely to be accomplished in the near future. In labs around the world, researchers looking for ways to help the sick and injured have stumbled onto techniques that enhance healthy animals—making them stronger, faster, smarter, and longer-lived—in some cases, even connecting their minds to robots and computers across the Internet. Now science is on the verge of applying this knowledge to healthy men and women, allowing us to alter humanity in ways we’d previously only dreamed possible. The same research that could cure Alzheimer’s is leading to drugs and genetic techniques that could boost human intelligence. The techniques being developed to stave off heart disease and cancer have the potential to slow or even reverse human aging. And brain implants that restore motion to the paralyzed and sight to the blind are already allowing a small set of patients to control robots and computers simply by thinking about it. Not everyone welcomes this scientific progress. Cries of “against nature” arise from skeptics even as scientists break new ground at an astounding pace. Across the political spectrum, the debate roils: Should we embrace the power to alter our minds and bodies, or should we restrict it? Distilling the most radical accomplishments being made in labs worldwide, including gene therapy, genetic engineering, stem cell research, life extension, brain-computer interfaces, and cloning,More Than Humanoffers an exciting tour of the impact biotechnology will have on our lives. Throughout this remarkable trip, author Ramez Naam shares an impassioned vision for the future with revealing insight into the ethical dilemmas posed by twenty-first-century science. Encouraging us to celebrate rather than fear these innovations, Naam incisively separates fact from myth, arguing that these much-maligned technologies have the power to transform the human race for the better, so long as individuals and families are left free to decide how and if to use them. If you’ve ever wondered about the boundaries of humanity,More Than Humanoffers a vision of a world where we use our knowledge to improve ourselves, unhindered by the fear of change.
Author: George Estreich
Publisher: MIT Press
ISBN: 0262351803
Category : Science
Languages : en
Pages : 239
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Book Description
How new biomedical technologies—from prenatal testing to gene-editing techniques—require us to imagine who counts as human and what it means to belong. From next-generation prenatal tests, to virtual children, to the genome-editing tool CRISPR-Cas9, new biotechnologies grant us unprecedented power to predict and shape future people. That power implies a question about belonging: which people, which variations, will we welcome? How will we square new biotech advances with the real but fragile gains for people with disabilities—especially when their voices are all but absent from the conversation? This book explores that conversation, the troubled territory where biotechnology and disability meet. In it, George Estreich—an award-winning poet and memoirist, and the father of a young woman with Down syndrome—delves into popular representations of cutting-edge biotech: websites advertising next-generation prenatal tests, feature articles on “three-parent IVF,” a scientist's memoir of constructing a semisynthetic cell, and more. As Estreich shows, each new application of biotechnology is accompanied by a persuasive story, one that minimizes downsides and promises enormous benefits. In this story, people with disabilities are both invisible and essential: a key promise of new technologies is that disability will be repaired or prevented. In chapters that blend personal narrative and scholarship, Estreich restores disability to our narratives of technology. He also considers broader themes: the place of people with disabilities in a world built for the able; the echoes of eugenic history in the genomic present; and the equation of intellect and human value. Examining the stories we tell ourselves, the fables already creating our futures, Estreich argues that, given biotech that can select and shape who we are, we need to imagine, as broadly as possible, what it means to belong.
Author: William AMZALLAG
Publisher: Lulu.com
ISBN: 2955855812
Category : Health & Fitness
Languages : en
Pages : 478
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Book Description
Live, in good health, for as long as possible! Yes, you can! Every day, our life expectancy increases by six hours, thanks to the advances of medical science and our improving lifestyle. Can we do better? Can we go as far as Jeanne Calment, the oldest person to have ever lived, who reached 122 years of age? Yes, it is possible! Today we are able to make a human cell immortal; what we do not yet know is how to do this for all of our cells, in all of our tissues, all of our organs, and for all of our functions. The author of this book draws us into the magical landscape of our 60 trillion intelligent cells. He shows us how aging gradually insinuates itself into our DNA. More importantly, he shares with us the incredible promises of stem cells, telomerase, biotechnology, nanomedicine, and, finally, the critical impact of a healthy lifestyle.
Author: A Joseph Henry Press book
Publisher: Joseph Henry Press
ISBN: 0309096219
Category : Science
Languages : en
Pages : 256
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Book Description
In this update to the very popular first edition of the same name, skilled science popularizer Eric Grace helps readers understand what biotechnology is and what implications it holds for all of us. Following on the heels of the success of the first edition, this thoroughly updated version offers an in-depth and accessible review of the basics of biotechnology. Accomplished science communicator Eric Grace focuses on the ethical implications involved, the wide range of public opinions both at home and abroad, the role of the media in communicating a complicated science topic, and the formidable problems associated with patenting life itself. With an emphasis on medicine, agriculture, and the environment, Grace explores the promises and realities of biotechnology. He deals frankly with the fact that biotechnology is first and foremost a commercial activity, often driven by big business and directed by the bottom line. And as biotechnology is used more frequently in medical diagnosis and treatment, we are witness to significant setbacks and reversals, dimming hopes that were prevalent when the first edition was released. But we are also witness to the burgeoning use of the technology in forensic science where DNA analysis has become commonplace in solving crimes. Likewise, DNA analysis has been a boon to studies of human history and evolution, revealing ancient details originally thought lost to us. At the same time, new uses for genetically altered bacteria are being discovered that help us clean up the environment by breaking down or sequestering toxic chemicals. While the public remains concerned about biotechnology, there is increasing awareness of the potential benefits. This updated edition of Biotechnology Unzipped helps put the many issues in perspective and provides answers to the most important questions.
Author: Craig Shimasaki
Publisher: Academic Press
ISBN: 0124047475
Category : Medical
Languages : en
Pages : 489
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Book Description
As an authoritative guide to biotechnology enterprise and entrepreneurship, Biotechnology Entrepreneurship and Management supports the international community in training the biotechnology leaders of tomorrow. Outlining fundamental concepts vital to graduate students and practitioners entering the biotech industry in management or in any entrepreneurial capacity, Biotechnology Entrepreneurship and Management provides tested strategies and hard-won lessons from a leading board of educators and practitioners. It provides a 'how-to' for individuals training at any level for the biotech industry, from macro to micro. Coverage ranges from the initial challenge of translating a technology idea into a working business case, through securing angel investment, and in managing all aspects of the result: business valuation, business development, partnering, biological manufacturing, FDA approvals and regulatory requirements. An engaging and user-friendly style is complemented by diverse diagrams, graphics and business flow charts with decision trees to support effective management and decision making. - Provides tested strategies and lessons in an engaging and user-friendly style supplemented by tailored pedagogy, training tips and overview sidebars - Case studies are interspersed throughout each chapter to support key concepts and best practices. - Enhanced by use of numerous detailed graphics, tables and flow charts
