The Gastrointestinal Circulation

The Gastrointestinal Circulation PDF Author: Peter R. Kvietys
Publisher: Morgan & Claypool Publishers
ISBN: 1615041176
Category : Medical
Languages : en
Pages : 127

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Book Description
The microcirculation of the gastrointestinal tract is under the control of both myogenic and metabolic regulatory systems. The myogenic mechanism contributes to basal vascular tone and the regulation of transmural pressure, while the metabolic mechanism is responsible for maintaining an appropriate balance between O2 demand and O2 delivery. In the postprandial state, hydrolytic products of food digestion elicit a hyperemia, which serves to meet the increased O2 demand of nutrient assimilation. Metabolically linked factors (e.g., tissue pO2, adenosine) are primarily responsible for this functional hyperemia. The fenestrated capillaries of the gastrointestinal mucosa are relatively permeable to small hydrolytic products of food digestion (e.g., glucose), yet restrict the transcapillary movement of larger molecules (e.g., albumin). This allows for the absorption of hydrolytic products of food digestion without compromising the oncotic pressure gradient governing transcapillary fluid movement and edema formation. The gastrointestinal microcirculation is also an important component of the mucosal defense system whose function is to prevent (and rapidly repair) inadvertent epithelial injury by potentially noxious constituents of chyme. Two pathological conditions in which the gastrointestinal circulation plays an important role are ischemia/reperfusion and chronic portal hypertension. Ischemia/reperfusion results in mucosal edema and disruption of the epithelium due, in part, to an inflammatory response (e.g., increase in capillary permeability to macromolecules and neutrophil infiltration). Chronic portal hypertension results in an increase in gastrointestinal blood flow due to an imbalance in vasodilator and vasoconstrictor influences on the microcirculation. Table of Contents: Introduction / Anatomy / Regulation of Vascular Tone and Oxygenation / Extrinsic Vasoregulation: Neural and Humoral / Postprandial Hyperemia / Transcapillary Solute Exchange / Transcapillary Fluid Exchange / Interaction of Capillary and Interstitial Forces / Gastrointestinal Circulation and Mucosal Defense / Gastrointestinal Circulation and Mucosal Pathology I: Ischemia/Reperfusion / Gastrointestinal Circulation and Mucosal Pathology II: Chronic Portal Hypertension / Summary and Conclusions / References / Author Biography

Portal Hypertension

Portal Hypertension PDF Author: Kunio Okuda
Publisher: Springer Science & Business Media
ISBN: 4431683615
Category : Medical
Languages : en
Pages : 554

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Book Description
Portal hypertension is the abnormal pathophysiologic state that develops in liver cirrhosis and certain other disorders with characteristic clinical and hemodynamic features. There has been great progress in our under standing and management of portal hypertension, particularly in the diagnostic and therapeutic approaches. The so-called Banti's syndrome, a disorder whose existence had long been questioned, is now a well-defined portal hypertensive disease. The recently introduced Doppler ftowmetry is currently yielding new information on portal hemodynamics. Endoscopic sclerotherapy and beta-blockers have come to be widely used in the man agement and prevention of variceal bleeding. In spite of all these advances, a number of unsolved questions remain, such as whether sclerotherapy, pharmacotherapy or surgery is warranted for prevention of bleeding, which is more effective as an elective treatment, the surgical or endoscopic approach, and whether surgical portacaval shunt should be totally replaced by selective shunt operations. These new developments and problems are clearly and comprehensively described and discussed by the foremost authorities in 44 chapters, which are divided into five sections: 1) Patho physiology, 2) Hemodynamic Investigations, 3) Imaging Investigations, 4) Clinical and Pathological Features, and 5) Esophageal and Gastrointestinal Bleeding. The primary goal of this monograph, to provide a framework of patho physiology of portal hypertension with authoritative descriptions of the clinical and laboratory manifestations of various portal hypertensive dis orders, has clearly been achieved by these excellent contributions.

CURRENT Diagnosis and Treatment Surgery: Thirteenth Edition

CURRENT Diagnosis and Treatment Surgery: Thirteenth Edition PDF Author: Gerard Doherty
Publisher: McGraw Hill Professional
ISBN: 0071635157
Category : Medical
Languages : en
Pages : 1328

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Book Description
To-the-point information on more than 1000 diseases and disorders surgeons are most likely to encounter The leading single-source surgery book for house-staff, students, practitioners, and surgeons A Doody's Core Title for 2011! "This is an excellent source of updated, authoritative, and concise information on diseases encountered in general surgery and the surgical subspecialties of otolaryngology, urology, gynecology, orthopedics, plastic and reconstructive surgery, and pediatrics....This is a wonderful resource for all levels of surgical practitioners as well as nonsurgical practitioners. In my experience, it has provided me with a framework to prepare for both oral and written boards. 3 Stars."--Doody's Review Service Authoritative, concise, and completely up-to-date, CURRENT Diagnosis & Treatment Surgery features: Wide-ranging coverage that encompasses general surgery and all the important subspecialties including otolaryngology, urology, gynecology, orthopedics, plastic and reconstructive surgery, and pediatrics References linked to recent journal articles Logical quick-find organization made even more accessible by a comprehensive index More than 600 informative photographs and illustrations Detailed treatment algorithms NEW CD-ROM with content from Quick Answers: Surgery to speed diagnosis of symptoms and signs NEW Chapter on Training, Communication, Professionalism, and Systems-Based Practice Completely rewritten chapters on Wound Healing, Anesthesia, Otolaryngology/Head & Neck Surgery, The Heart, Neurosurgery, Gynecology, and Orthopedics

Anatomy for the FRCA

Anatomy for the FRCA PDF Author: James Bowness
Publisher: Cambridge University Press
ISBN: 1108701884
Category : Medical
Languages : en
Pages : 183

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Book Description
This practical, comprehensive anatomy book arms FRCA candidates with detailed, robust anatomical knowledge via a question-based approach.

Vascular Disorders of the Liver

Vascular Disorders of the Liver PDF Author: Dominique Valla
Publisher: Springer Nature
ISBN: 303082988X
Category : Medical
Languages : en
Pages : 376

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Book Description
This book provides a comprehensive account on individually rare, but collectively frequent diseases of the liver. In the first part, conditions such as hepatic vascular malformations, ischemic cholangiopathy, hepatic artery occlusion, sinusoidal conditions and Budd-Chiari syndrome are discussed among others. The second part examines the causes of vascular liver disease namely, coagulation disorders, neoplasm disorders, non-malignant blood disorders, systemic diseases and toxins, among others. The unique expertise of the authors, who are all members of the Vascular Liver Disease Disorders Group, an independent network of researchers with a common interest in Vascular Liver Diseases, are merged for an optimal pragmatic and individualized approach. This book is of interest to a broad range of experts, such as hepatologists, internists, radiologists and angiologists.

Atlas of Critical Care Echocardiography

Atlas of Critical Care Echocardiography PDF Author: Alexis Salerno
Publisher: Springer Nature
ISBN: 3030746879
Category : Medical
Languages : en
Pages : 192

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Book Description
This atlas covers the basics of ultrasound physics, provides the necessary background to successfully perform TEE and TTE procedures, and provides tips and tricks that will prove invaluable in the critical care environment. It also features an abundance of high quality photographs, illustrations and videos as well as numerous case studies to test the reader's ability to apply knowledge to real-life clinical situations. Written by experts in the field, The Atlas of Critical Care Echocardiography is a concise, visual guide designed for use by all physicians who see cardiac patients in the ICU.

Diseases of the Abdomen and Pelvis 2018-2021

Diseases of the Abdomen and Pelvis 2018-2021 PDF Author: Juerg Hodler
Publisher: Springer
ISBN: 3319750194
Category : Medical
Languages : en
Pages : 262

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Book Description
This open access book deals with imaging of the abdomen and pelvis, an area that has seen considerable advances over the past several years, driven by clinical as well as technological developments. The respective chapters, written by internationally respected experts in their fields, focus on imaging diagnosis and interventional therapies in abdominal and pelvic disease; they cover all relevant imaging modalities, including magnetic resonance imaging, computed tomography, and positron emission tomography. As such, the book offers a comprehensive review of the state of the art in imaging of the abdomen and pelvis. It will be of interest to general radiologists, radiology residents, interventional radiologists, and clinicians from other specialties who want to update their knowledge in this area.

Handbook of Pediatric Surgery

Handbook of Pediatric Surgery PDF Author: Chandrasen K. Sinha
Publisher: Springer Science & Business Media
ISBN: 1848821328
Category : Medical
Languages : en
Pages : 464

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Book Description
Although pediatric surgery is a distinct and evolving specialty, it still remains an integral part of most general surgical and paediatric medical practice. Nevertheless, surgery in children does differ from adult practice in various fundamental ways, and there are key physiological and anatomical differences that constantly need underlining. Progress and improvement in outcome has also been rapid but it is sometimes difficult for practitioners to keep themselves up-to-date with the usual surgical or paediatric text books. This book will give a concise overview of all important topics and is designed to provide information in order to recognise the common surgical conditions; namely typical symptoms and signs, investigation and then treatment management. It will also provide an anatomical and physiological background to aid understanding, in addition to emphasising logical, and where possible, evidence-based practice by the use of flow charts, tables and algorithms. Authored by an international range of leading contributors, this is the first book of its kind to offer comprehensive coverage to this topic in a quick reference, pocket-book format.

The Genetic Landscape of Diabetes

The Genetic Landscape of Diabetes PDF Author: Laura Dean
Publisher:
ISBN:
Category :
Languages : en
Pages :

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Book Description


Body MDCT in Small Animals

Body MDCT in Small Animals PDF Author: Giovanna Bertolini
Publisher: Springer
ISBN: 3319469045
Category : Science
Languages : en
Pages : 443

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Book Description
This book is an up-to-date, technically detailed yet easy-to-read reference book on current clinical applications of MDCT in small animals. It has been designed to serve as the reference book for all MDCT-users, such as veterinary radiologists, imaging technicians, oncologists, surgeons, and non-radiologist clinicians. Individual chapters on novel clinically important topics include applications in endocrinology, oncology, trauma, and cardiovascular CT, as well as sections on organ-specific pathologies and their CT characteristics. The book will also cover main domains of CT, such as thorax and the trauma imaging. Anatomy, clinical aspects, pathology, and CT signs are integrated to provide the reader with the basis for interpretation of MDCT findings. Many excellent 2D multiplanar and 3D figures illustrating typical CT findings of various conditions will serve as a clinical reference for the reader.