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Author: Francis O. Schmitt
Publisher: Mit Press
ISBN: 9780262693066
Category : Medical
Languages : en
Pages : 614
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Book Description
These published proceedings of a Neurosciences Research Program Colloquium do not deal exhaustively with particular cortical issues—rather, they convey the highlights of the topic, beginning with a series of presentations on the ontogenetic and morphogenetic development of the cerebral cortex followed by a systematic view of the remarkable explosion during the last decade of our knowledge of the cellular organization and connectively of the cortex. All of the topics in the book are put into perspective in an opening keynote by W. Maxwell Cowan. He there observes that theoretical constructs (or the lack of them) are the weakest aspect of neurobiology at the moment. Thus the book's final section (with contributions by three Nobel laureates—Francis Crick, Gerald Edelman, and Leon Cooper—among others) is a meaningful new effort toward redressing the balance.
Author: Francis O. Schmitt
Publisher: Mit Press
ISBN: 9780262693066
Category : Medical
Languages : en
Pages : 614
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Book Description
These published proceedings of a Neurosciences Research Program Colloquium do not deal exhaustively with particular cortical issues—rather, they convey the highlights of the topic, beginning with a series of presentations on the ontogenetic and morphogenetic development of the cerebral cortex followed by a systematic view of the remarkable explosion during the last decade of our knowledge of the cellular organization and connectively of the cortex. All of the topics in the book are put into perspective in an opening keynote by W. Maxwell Cowan. He there observes that theoretical constructs (or the lack of them) are the weakest aspect of neurobiology at the moment. Thus the book's final section (with contributions by three Nobel laureates—Francis Crick, Gerald Edelman, and Leon Cooper—among others) is a meaningful new effort toward redressing the balance.
Author: WHITE
Publisher: Springer Science & Business Media
ISBN: 1468487213
Category : Medical
Languages : en
Pages : 224
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Book Description
This elegant book presents current evidence on the organization of the mammalian cerebral cortex. The focus on synapses and their function provides the basis for understanding how this critical part of the brain could work. Dr. White and his colleague Dr. Keller have collated an impressive mass of material. This makes the crucial information accessible and coherent. Dr. White pioneered an area of investigation that to most others, and occasionally to himself, seemed a bottomless pit of painstaking at tention to detail for the identification and enumeration of cortical syn apses. I do not recall that he or anyone else suspected, when he began to publish his now classic papers, that the work would be central to an accelerating convergence of information and ideas from neurobiology and computer science, especially artificial intelligence (AI) (Rumelhart and McClelland, 1986). The brain is the principal organ responsible for the adaptive capacities of animals. What has impressed students of biology, of medicine, and, to an extent, of philosophy is the correlation between the prominence of the cerebral cortex and the adaptive "complexity" of a particular spe cies. Most agree that the cortex is what sets Homo sapiens apart from other species quantitatively and qualitatively (Rakic, 1988). This is summarized in the first chapter.
Author: National Academy of Sciences
Publisher: National Academies Press
ISBN: 0309045290
Category : Medical
Languages : en
Pages : 195
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Book Description
The brain ... There is no other part of the human anatomy that is so intriguing. How does it develop and function and why does it sometimes, tragically, degenerate? The answers are complex. In Discovering the Brain, science writer Sandra Ackerman cuts through the complexity to bring this vital topic to the public. The 1990s were declared the "Decade of the Brain" by former President Bush, and the neuroscience community responded with a host of new investigations and conferences. Discovering the Brain is based on the Institute of Medicine conference, Decade of the Brain: Frontiers in Neuroscience and Brain Research. Discovering the Brain is a "field guide" to the brainâ€"an easy-to-read discussion of the brain's physical structure and where functions such as language and music appreciation lie. Ackerman examines: How electrical and chemical signals are conveyed in the brain. The mechanisms by which we see, hear, think, and pay attentionâ€"and how a "gut feeling" actually originates in the brain. Learning and memory retention, including parallels to computer memory and what they might tell us about our own mental capacity. Development of the brain throughout the life span, with a look at the aging brain. Ackerman provides an enlightening chapter on the connection between the brain's physical condition and various mental disorders and notes what progress can realistically be made toward the prevention and treatment of stroke and other ailments. Finally, she explores the potential for major advances during the "Decade of the Brain," with a look at medical imaging techniquesâ€"what various technologies can and cannot tell usâ€"and how the public and private sectors can contribute to continued advances in neuroscience. This highly readable volume will provide the public and policymakersâ€"and many scientists as wellâ€"with a helpful guide to understanding the many discoveries that are sure to be announced throughout the "Decade of the Brain."
Author: Donald Arthur Sholl
Publisher:
ISBN:
Category :
Languages : en
Pages : 125
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Book Description
Author: D. A. Sholl
Publisher:
ISBN: 9780028522302
Category : Cerebral cortex
Languages : en
Pages : 138
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Book Description
Author: Francis Otto Schmitt
Publisher:
ISBN:
Category : Cerebral cortex
Languages : en
Pages : 592
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Book Description
Author: Ryoichiro Kageyama
Publisher: Springer Science & Business Media
ISBN: 4431544968
Category : Medical
Languages : en
Pages : 282
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Book Description
This book reviews recent progress in cortical development research, focusing on the mechanisms of neural stem cell regulation, neuronal diversity and connectivity formation, and neocortical organization. Development of the cerebral cortex, the center for higher brain functions such as cognition, memory, and decision making, is one of the major targets of current research. The cerebral cortex is divided into many areas, including motor, sensory, and visual cortices, each of which consists of six layers containing a variety of neurons with different activities and connections. As this book explains, such diversity in neuronal types and connections is generated at various levels. First, neural stem cells change their competency over time, giving sequential rise to distinct types of neurons and glial cells: initially deep layer neurons, then superficial layer neurons, and lastly astrocytes. The activities and connections of neurons are further modulated via interactions with other brain regions, such as the thalamocortical circuit, and via input from the environment. This book on cortical development is essential reading for students, postdocs, and neurobiologists.
Author: Deepak N. Pandya
Publisher: Oxford University Press, USA
ISBN: 0195385152
Category : Medical
Languages : en
Pages : 481
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Book Description
This comprehensive and detailed work covering the fascinatingly organized architecture and connections of the cerebral cortex. After establishing the evolutionary approach of the origin of the cerebral cortex, the authors have systematically analyzed, in detail, the common principle underlying the architecture and connections of sensory and motor systems. The frontal, limbic, and multimodal association areas, as well as the long fiber pathways, are thoroughly discussed. The anatomical investigations have been complimented with current clinical and experimental observations, as well as neuroimaging studies. This unique approach, exploring the underlying principle of the architecture and connections of the cerebral cortex, has previously never been undertaken. In the concluding chapter of the book, the authors have provided the usefulness of such an approach for future investigations. Filled with extensive illustrations and historical references to each sensory, motor, and association systems, this monograph is essential for academics seeking a deeper understanding of the cerebral cortex.
Author: Ryszard M. Pluta
Publisher:
ISBN:
Category :
Languages : en
Pages : 224
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Book Description
Cerebral ischemia is one of the most common causes of dementia, which develops in more than half of patients after an ischemic episode. The main mechanism is thought to be pathological changes in the hippocampus, especially in the CA1 area, underlying episodic memory impairment, which is the earliest and most important clinical symptom of post-ischemic dementia. The 13 chapters of this book present a new picture of ischemic brain disease, synthesizing the latest data on disease mechanisms, care for patients with this disease, and potential therapeutic targets. The authors present the characteristics of cerebral ischemia from pregnancy and childhood through adolescence to adulthood. The first two chapters provide a snapshot of the anatomy of the cerebral cortex and the hippocampus, the most affected brain structures after cerebral ischemia. This is followed by nine chapters that present a comprehensive view of the pathological mechanisms of cerebral ischemia, and how a deep understanding of these pathomechanisms hold the key for the discovery and development of novel therapies to help patients affected by cerebral ischemia. Chapter 12 shares real-life experience and challenges of rehabilitating patients into the community after cerebral ischemia, and chapter 13 analyzes the social risk variations, including gender inequality, in the reintegration of post-ischemic stroke patients. Although primarily aimed at scientists and clinicians, the contents of the book will be of interest to all those who are interested in cerebral ischemia, including patients and their caregivers.
Author: Henry Kennedy
Publisher: Springer
ISBN: 3319277774
Category : Medical
Languages : en
Pages : 173
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Book Description
This book has brought together leading investigators who work in the new arena of brain connectomics. This includes ‘macro-connectome’ efforts to comprehensively chart long-distance pathways and functional networks; ‘micro-connectome’ efforts to identify every neuron, axon, dendrite, synapse, and glial process within restricted brain regions; and ‘meso-connectome’ efforts to systematically map both local and long-distance connections using anatomical tracers. This book highlights cutting-edge methods that can accelerate progress in elucidating static ‘hard-wired’ circuits of the brain as well as dynamic interactions that are vital for brain function. The power of connectomic approaches in characterizing abnormal circuits in the many brain disorders that afflict humankind is considered. Experts in computational neuroscience and network theory provide perspectives needed for synthesizing across different scales in space and time. Altogether, this book provides an integrated view of the challenges and opportunities in deciphering brain circuits in health and disease.
