Handbook of Clinical Trials in Ophthalmology

Handbook of Clinical Trials in Ophthalmology PDF Author: Vinod Kumar
Publisher: Jaypee Brothers Medical Publishers
ISBN: 939059507X
Category : Medical
Languages : en
Pages : 442

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Book Description
This handbook is a compilation of major clinical trials in all subspecialties in the field of ophthalmology. Each trial is presented in a uniform manner, detailing the background and purpose of the study, design, number of subjects with inclusion and exclusion criteria, outcomes, then results and conclusions. Topics include glaucoma, cornea, diabetic retinopathy, age-related macular degeneration, retinal detachment, neuro-ophthalmology, ocular melanoma, and many more. Trials are arranged chronologically or in order of significance, with extensive referencing for further reading. ‘At a glance’ tables summarising each trial are also included. The previous edition of this comprehensive text (9789350907740) published in 2013.

Handbook of Clinical Trials in Ophthalmology

Handbook of Clinical Trials in Ophthalmology PDF Author: Vinod Kumar
Publisher: Jaypee Brothers Medical Publishers
ISBN: 939059507X
Category : Medical
Languages : en
Pages : 442

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Book Description
This handbook is a compilation of major clinical trials in all subspecialties in the field of ophthalmology. Each trial is presented in a uniform manner, detailing the background and purpose of the study, design, number of subjects with inclusion and exclusion criteria, outcomes, then results and conclusions. Topics include glaucoma, cornea, diabetic retinopathy, age-related macular degeneration, retinal detachment, neuro-ophthalmology, ocular melanoma, and many more. Trials are arranged chronologically or in order of significance, with extensive referencing for further reading. ‘At a glance’ tables summarising each trial are also included. The previous edition of this comprehensive text (9789350907740) published in 2013.

Ophthalmology Clinical Trials Handbook

Ophthalmology Clinical Trials Handbook PDF Author: Laura Vickers
Publisher: Nova Science Publishers
ISBN: 9781634821032
Category : Clinical trials
Languages : en
Pages : 0

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Book Description
The field of ophthalmology has advanced considerably in the past several decades in terms of surgical and technical advancements, understanding the mechanism of diseases and treating conditions that were once considered untreatable. As is the case with so many other specialties in medicine, ophthalmology is guided by "evidence based medicine," based on the results of randomised controlled trials (RCTs). To put this powerful information in the hands of clinicians, this handbook was developed to provide a succinct yet comprehensive review of the most essential evidence-based medicine in ophthalmology. This essential text forms a framework for the evidence-based clinical practice of ophthalmic technicians, residents, academic and private practitioners of ophthalmology as well as researchers, optometrists and others. It also serves as a core review text for tests such as the OKAP and ophthalmology board exams, which emphasise knowledge based in the outcomes of major RCTs. This text covers the major research carried out in all of the subspecialties of ophthalmology including cornea, medical and surgical retina, glaucoma, oculoplastics, neuro-ophthalmology, and pediatric ophthalmology. Each chapter has been carefully edited by top academic faculty at the Duke University Eye Center, who have an intimate understanding of the essential knowledge contained within the current ophthalmic literature and have contributed commentary on the results. This book therefore is not only a convenient review of the vital knowledge in ophthalmology, but also provides a keen analysis by world experts of the most up-to-date research in their respective fields. In short, this book promises to change the way eye care professionals use RCTs in clinical practice by putting this powerful information conveniently in their hands.

The Ophthalmology Clinical Trials Handbook

The Ophthalmology Clinical Trials Handbook PDF Author: M. Tariq Bhatti
Publisher:
ISBN: 9781634821049
Category : MEDICAL
Languages : en
Pages : 471

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Book Description
The field of ophthalmology has advanced considerably in the past several decades in terms of surgical and technical advancements, understanding the mechanism of diseases and treating conditions that were once considered untreatable. As is the case with so many other specialties in medicine, ophthalmology is guided by "evidence based medicine," based on the results of randomized controlled trials (RCTs). To put this powerful information in the hands of clinicians, this handbook was developed to provide a succinct yet comprehensive review of the most essential evidence-based medicine in ophthalmology. This essential text forms a framework for the evidence-based clinical practice of ophthalmic technicians, residents, academic and private practitioners of ophthalmology as well as researchers, optometrists and others. It also serves as a core review text for tests such as the OKAP and ophthalmology board exams, which emphasize knowledge based in the outcomes of major RCTs. This text covers the major research carried out in all of the subspecialties of ophthalmology including cornea, medical and surgical retina, glaucoma, oculoplastics, neuro-ophthalmology, and pediatric ophthalmology. Each chapter has been carefully edited by top academic faculty at the Duke University Eye Center, who have an intimate understanding of the essential knowledge contained within the current ophthalmic literature and have contributed commentary on the results. This book therefore is not only a convenient review of the vital knowledge in ophthalmology, but also provides a keen analysis by world experts of the most up-to-date research in their respective fields. In short, this book promises to change the way eye care professionals use RCTs in clinical practice by putting this powerful information conveniently in their hands.

Handbook of Clinical Trials in Ophthalmology

Handbook of Clinical Trials in Ophthalmology PDF Author: Vinod Kumar
Publisher:
ISBN: 9789354657184
Category : Clinical trials
Languages : en
Pages : 0

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Book Description


Pivotal Trials in Ophthalmology

Pivotal Trials in Ophthalmology PDF Author: Jenny C. Dohlman
Publisher: Springer Nature
ISBN: 3030639789
Category : Medical
Languages : en
Pages : 176

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Book Description
Pivotal Trials in Ophthalmology: A Guide for Trainees is an introductory text designed to give trainees a comprehensive and accessible overview of landmark trials in the different subspecialties of ophthalmology, and may also serve as a useful reference for practicing ophthalmologists, optometrists and researchers in the field. The text is subdivided by subspecialty, with each chapter authored by both a trainee and an expert in the field. A selection of pivotal research studies that have shaped how practitioners diagnose, manage, and treat disease are reviewed in chronological order. The purpose, study design, results, and study limitations are reviewed, and the key takeaway points from each study are listed in a digestible, bullet-point format. By listing the studies in chronological order, the reader will have an understanding of how studies have built upon each other and how knowledge has evolved over time. This text can serve as a basic introductory text for first year ophthalmology residents around which a standardized curriculum can be shaped, a study guide for board examination study, or a reference text for practitioners and researchers at any stage of training and practice.

Clinical Trials Handbook

Clinical Trials Handbook PDF Author: Shayne Cox Gad
Publisher: John Wiley & Sons
ISBN: 0470466359
Category : Science
Languages : en
Pages : 1247

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Book Description
Best practices for conducting effective and safe clinical trials Clinical trials are arguably the most important steps in proving drug effectiveness and safety for public use. They require intensive planning and organization and involve a wide range of disciplines: data management, biostatistics, pharmacology, toxicology, modeling and simulation, regulatory monitoring, ethics, and particular issues for given disease areas. Clinical Trials Handbook provides a comprehensive and thorough reference on the basics and practices of clinical trials. With contributions from a range of international authors, the book takes the reader through each trial phase, technique, and issue. Chapters cover every key aspect of preparing and conducting clinical trials, including: Interdisciplinary topics that have to be coordinated for a successful clinical trialData management (and adverse event reporting systems) Biostatistics, pharmacology, and toxicology Modeling and simulation Regulatory monitoring and ethics Particular issues for given disease areas-cardiology, oncology, cognitive, dementia, dermatology, neuroscience, and more With unique information on such current issues as adverse event reporting (AER) systems, adaptive trial designs, and crossover trial designs, Clinical Trials Handbook will be a ready reference for pharmaceutical scientists, statisticians, researchers, and the many other professionals involved in drug development.

Oxford Handbook of Ophthalmology

Oxford Handbook of Ophthalmology PDF Author: Alastair K. O. Denniston
Publisher: Oxford University Press
ISBN: 019252674X
Category : Medical
Languages : en
Pages : 1249

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Book Description
Fully revised and updated throughout, the fourth edition of the Oxford Handbook of Ophthalmology now includes free access to the ophthalmic online media bank, a selection of high-quality clinical images and videos for a wide breadth of key ophthalmic diseases. Clear, concise, and practical, this handbook provides immediate access to the detailed clinical information you need, in casualty, clinic, theatre, and on the wards. The core of the book comprises a systematic synopsis of ophthalmic disease directed towards diagnosis, interim assessment, and ongoing management. Assessment boxes for common clinical conditions and algorithms for important clinical presentations illustrate this practical approach. The information is easily accessible, presented in a clear format with areas of importance highlighted. Key sections for the trainee include: Clinical Skills, Aids to Diagnosis, Investigations and their Interpretation, Perioperative Care, Theatre Notes and Therapeutics. The wider practise of eye-care is supported by expanded chapters on Refractive Ophthalmology, Vision in Context, Evidence Based Ophthalmology and Resources for Ophthalmologists. Now including newer treatments across a range of specialities such as SMILE, gene-therapy and retinal prostheses, as well as greater emphasis on the evidence underlying current clinical practice and guidelines, this handbook has never been more essential for all those working in eye-care. Whether you want to learn about patient-reported outcomes, identify a surgical instrument, interpret a statistical test, or diagnose and treat ophthalmic emergencies, you will find it here. Whatever your role in caring for patients with eye disease: ophthalmologist, optometrist, orthoptist, ophthalmic nurse, or other health profession - discover for yourself why this handbook has become the 'go-to' resource for tens of thousands of eye-care professionals around the world.

Clinical Trials Handbook

Clinical Trials Handbook PDF Author: Curtis L. Meinert
Publisher: John Wiley & Sons
ISBN: 1118422791
Category : Reference
Languages : en
Pages : 469

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Book Description
A systematic approach to all aspects of designing and conducting clinical trials The success or failure of clinical trials hinges on hundreds of details that need to be developed, often under less than ideal conditions. Written by one of the world's leading trialists, Clinical Trials Handbook: Design and Conduct provides clinicians with a complete guide to designing, conducting, and evaluating clinical trials—teaching them how to simplify the process and avoid costly mistakes. The author draws on his extensive clinical trials experience to outline all steps employed in setting up and running clinical trials, from budgeting and fundraising to publishing the results. Along the way, practical advice is offered while also addressing a mix of logistical, ethical, psychological, behavioral, and administrative issues inherent to clinical trials. Topics of coverage include: Protocols for drug masking, controls, and treatment randomization Consent, enrollment, eligibility, and follow-up procedures Different types of sample size design and data collection and processing Working with study centers, research staff, and various committees Monitoring treatment effects and performance, and ensuring quality control Data analysis and access policies for study data and documents Clinical Trials Handbook is invaluable for practicing clinicians and trialists who would like to learn more about or improve their understanding of the design and execution of clinical trials. The book is also an excellent supplement for courses on clinical trials at the graduate level.

Handbook of Basic and Clinical Ocular Pharmacology and Therapeutics

Handbook of Basic and Clinical Ocular Pharmacology and Therapeutics PDF Author: Sunny Ohia
Publisher: Academic Press
ISBN: 0128192925
Category : Medical
Languages : en
Pages : 673

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Book Description
Handbook of Basic and Clinical Ocular Pharmacology and Therapeutics provides a review of the basic anatomy, physiology, biochemistry and pathology of the eye with a focus drug therapy, drug delivery and use of therapeutic medical miniature devices. An understanding of the pharmacological actions of drugs acting on the eye requires the student and health care practitioner to learn additional principles in basic and clinical sciences that are unique to this organ. As a sensory organ, the eye is relatively inaccessible to the systemic circulation due to the blood-vitreous, blood-aqueous and blood-retinal barriers. Consequently, the administration of drugs for therapeutic effects in the eye necessitates an understanding of physico-chemical properties of the molecules and pharmacokinetic principles involved in the access to its site of action via topical, intracameral and intravitreal administration. This book includes information on the general principles of pharmacokinetics and pharmacodynamics of drugs as it pertains to the eye and in combating ocular disorders and diseases. Using a disease-themed approach, the book discusses basic and clinical pharmacological principles involved in the therapy of these diseases including the ocular side effect of systemically-administered drugs, drugs used in ophthalmic surgery and miscellaneous agents, the therapeutic utility of biologics, drug conjugates, combination products, gene and cellular therapy are also covered. Handbook of Basic and Clinical Ocular Pharmacology and Therapeutics is useful as a primary and secondary source of reference for up-to-date information about the pharmacological mechanisms of action, pharmacokinetics, side effects, drug-drug interactions and therapeutic indications of drugs for pharmacologists, pharmaceutical scientists, students in the health care disciplines (nursing, pharmacy, optometry, medical), and practitioners in optometry and ophthalmology. Explains the mechanisms of action, side-effects and therapeutic uses of drugs, biologics, miniature devices, gene and cellular therapies for the eye Provides a comprehensive review of the anatomy, physiology, biochemistry, pharmacology, microbiology, genetics and pathology of parts of the eye involved in drug therapy to combat eye disorders and diseases Explores the pharmacological and clinical basis of drugs, drug conjugates, combination products used in the treatment of anterior and posterior segment diseases

Ocular Therapeutics Handbook

Ocular Therapeutics Handbook PDF Author: Bruce E. Onofrey
Publisher: Lippincott Williams & Wilkins
ISBN: 1451153708
Category : Medical
Languages : en
Pages : 1057

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Book Description
Ocular Therapeutics Handbook: A Clinical Manual is directed at the needs of optometrists, nurses and primary care physicians and provides succinct, rapid access information for most common ocular problems encountered in a primary care setting. It is divided into three sections: Quick Reference, Ocular Therapeutics and Appendices. The Quick Reference section covers such topics as ocular microbiology, lab tests and procedures, pharmaceutical agents, and side effects of medications. The Ocular Therapeutics section discusses diseases, traumatic injuries, and ocular urgencies and emergencies. The appendices provide a summary of abbreviations, conversion charts, case report sheets and important phone numbers. The chapters have been developed to serve as a snapshot, presenting the clinician with the most relevant information regarding the pathophysiology and etiology of diseases, patient demographics, signs and symptoms, lab tests, and recommended approaches to treatment.