The New Paradigm of Immunity to Tuberculosis

The New Paradigm of Immunity to Tuberculosis PDF Author: Maziar Divangahi
Publisher: Springer Science & Business Media
ISBN: 1461461111
Category : Medical
Languages : en
Pages : 295

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Book Description
This book illustrates the intimate relationship between alveolar macrophages and Mycobacterium tuberculosis (M.tb.), and the former’s role in both innate and adaptive immunity against M.tb. It covers research done over the last decade. It also explores the role of macrophage death following infection with M.tb. in determining whether successful immunity is stimulated, or whether clinical disease develops; furthermore, the function of host lipid mediators in macrophage death modality are addressed. The book also illustrates how the balance between prostaglandins and lipoxins determines whether infected macrophages undergo apoptosis or necrosis, which is the ultimate factor in the outcome of infection. Finally, it is a synthesis of the authors’ recent studies and the studies of others to offer a new understanding of immunity to tuberculosis.

The New Paradigm of Immunity to Tuberculosis

The New Paradigm of Immunity to Tuberculosis PDF Author: Maziar Divangahi
Publisher: Springer Science & Business Media
ISBN: 1461461111
Category : Medical
Languages : en
Pages : 295

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Book Description
This book illustrates the intimate relationship between alveolar macrophages and Mycobacterium tuberculosis (M.tb.), and the former’s role in both innate and adaptive immunity against M.tb. It covers research done over the last decade. It also explores the role of macrophage death following infection with M.tb. in determining whether successful immunity is stimulated, or whether clinical disease develops; furthermore, the function of host lipid mediators in macrophage death modality are addressed. The book also illustrates how the balance between prostaglandins and lipoxins determines whether infected macrophages undergo apoptosis or necrosis, which is the ultimate factor in the outcome of infection. Finally, it is a synthesis of the authors’ recent studies and the studies of others to offer a new understanding of immunity to tuberculosis.

Global Tuberculosis Control

Global Tuberculosis Control PDF Author: World Health Organization
Publisher: World Health Organization
ISBN: 9241563540
Category : Outcome assessment (Medical care)
Languages : en
Pages : 305

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Book Description
WHO's twelfth annual report on global tuberculosis control in a series that started in 1997.

Tuberculosis

Tuberculosis PDF Author: Wellman Ribón
Publisher: BoD – Books on Demand
ISBN: 9535121391
Category : Medical
Languages : en
Pages : 242

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Book Description
Progress obtained by mycobacteriology in recent years is undeniable with regards to preventing, detecting, and treating cases of tuberculosis, millennial disease that is still present as public health issue worldwide. We present here high-impact research and interest topics related to the application of new methodologies, especially molecular methods for rapid diagnostic such as rapid DST, application of high performance liquid chromatography, molecular epidemiology and molecular diagnostic testing on post mortem. Currently, the constant search for vaccines that prevent the disease is promising through research of the immune response generated by the host towards the bacterium, and the effectiveness that may be achieved from developed vaccines. Another high-impact factor is the one generated by considering tuberculosis as a social disease with an infectious component reflected in research about tuberculosis and human rights. Finally, we present important issues of the pathogen interaction with different hosts. The constant knowledge generation that expands the frontiers of understanding is a key factor for finding solutions and successful activities for public health.

The Tubercle Bacillus in the Pulmonary Lesion of Man

The Tubercle Bacillus in the Pulmonary Lesion of Man PDF Author: Georges Canetti
Publisher:
ISBN:
Category : Bacillus tuberculosis
Languages : en
Pages : 248

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Book Description


The Pathogenesis of Tuberculosis

The Pathogenesis of Tuberculosis PDF Author: Arnold Rice Rich
Publisher:
ISBN:
Category : Tuberculosis
Languages : en
Pages : 1076

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Book Description


Clinical Tuberculosis

Clinical Tuberculosis PDF Author: Peter D. O. Davies
Publisher: CRC Press
ISBN: 0429586493
Category : Medical
Languages : en
Pages : 482

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Book Description
Completely updated and revised, Clinical Tuberculosis continues to provide the TB practitioner-whether in public health, laboratory science or clinical practice-with a synoptic and definitive account of the latest methods of diagnosis, treatment and control of this challenging and debilitating disease.New in the Fifth Edition:Gamma interferon-based

A Color Atlas of Comparative Pathology of Pulmonary Tuberculosis

A Color Atlas of Comparative Pathology of Pulmonary Tuberculosis PDF Author: Franz Joel Leong
Publisher: CRC Press
ISBN: 1439835306
Category : Medical
Languages : en
Pages : 230

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Book Description
An annual death toll of 2 million, coupled with rising drug resistance, highlights the need for the development of new drugs, better diagnostics, and a tuberculosis (TB) vaccine. Addressing these key issues, A Color Atlas of Comparative Pathology of Pulmonary Tuberculosis introduces TB histopathology to the non-histopathologists, students, scientis

Pathogenesis of Mycobacterium tuberculosis and its Interaction with the Host Organism

Pathogenesis of Mycobacterium tuberculosis and its Interaction with the Host Organism PDF Author: Jean Pieters
Publisher: Springer
ISBN: 9783662521427
Category : Medical
Languages : en
Pages : 0

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Book Description
Mycobacterium tuberculosis is one of the most notorious pathogens on earth, causing the death of approximately 1.5 million people annually. A major problem in the fight against tuberculosis is the emergence of strains that have acquired resistance to all available antibiotics. One key to the success of M. tuberculosis as a pathogen is its ability to circumvent host immune responses at different levels. This is not only a result of the special makeup of M. tuberculosis in terms of genetic diversity and DNA metabolism and its possession of specialized secretion systems, but also of its ability to hijack the host’s innate immune defence mechanisms. In this volume, researchers from different disciplines provide a topical overview of the diverse mechanisms that contribute to the virulence of M. tuberculosis, ranging from their genetic, metabolic and molecular makeup, as well as the complex strategies these bacteria utilize to escape immune destruction within infected hosts.

Global Tuberculosis Report 2017

Global Tuberculosis Report 2017 PDF Author: World Health Organization
Publisher: World Health Organization
ISBN: 9789241565516
Category : Medical
Languages : en
Pages : 0

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Book Description
WHO's Global Tuberculosis Report provides a comprehensive and up-to-date assessment of the TB epidemic and of progress in care and prevention at global, regional and country levels. This is done in the context of recommended global TB strategies and associated targets, and broader development goals. For the period 2016-2035, these are WHO's End TB Strategy and the United Nations' (UN) Sustainable Development Goals (SDGs), which share a common aim: to end the global TB epidemic. The main data sources for the report are annual rounds of global TB data collection implemented by WHO's Global TB Program since 1995 and databases maintained by other WHO departments, UNAIDS and the World Bank. In WHO's 2017 round of global TB data collection, 201 countries and territories that account for over 99% of the world's population and TB cases reported data.

Trained Immunity-based Vaccines

Trained Immunity-based Vaccines PDF Author: Jose Luis Subiza
Publisher: Frontiers Media SA
ISBN: 2889712311
Category : Medical
Languages : en
Pages : 195

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Book Description
Dr. Jose Luis Subiza is the founder and CEO of Inmunotek SL. The other Topic Editors declare no competing interests with regard to the Research Topic subject.