The Neurobiology of the Gilles De La Tourette Syndrome and Chronic Tics: Part B PDF Download
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Author:
Publisher: Academic Press
ISBN: 0323910378
Category : Technology & Engineering
Languages : en
Pages : 402
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Book Description
The Neurobiology of the Gilles de la Tourette Syndrome and Chronic Tics, Part B, Volume Four reviews historical background, current nosology and guidelines. In addition, it includes an overview of pathophysiology, ranging from its genetic basis and changes in neurochemistry and electrophysiology to widespread neural circuits. Specific chapters cover The genetic basis of Gilles de la Tourette Syndrome, Genome-wide association study of Tourette Syndrome, De Novo mutations in Tourette Syndrome, Animal models for Tourette Syndrome, The neural-immune crosstalk in Tourette syndrome: from immunobiology to epistemology, Functional connectivity in the Gilles de la Tourette Syndrome, and much more. - Includes examines of Gilles de la Tourette Syndrome at behavioral, cognitive, clinical, electrophysiological, molecular and genetic levels - Provides a comprehensive overview of the neurobiological aspects of Gilles de la Tourette Syndrome - Edited and authored by top researchers and clinicians treating Gilles de la Tourette Syndrome
Author:
Publisher: Academic Press
ISBN: 0323910378
Category : Technology & Engineering
Languages : en
Pages : 402
Get Book Here
Book Description
The Neurobiology of the Gilles de la Tourette Syndrome and Chronic Tics, Part B, Volume Four reviews historical background, current nosology and guidelines. In addition, it includes an overview of pathophysiology, ranging from its genetic basis and changes in neurochemistry and electrophysiology to widespread neural circuits. Specific chapters cover The genetic basis of Gilles de la Tourette Syndrome, Genome-wide association study of Tourette Syndrome, De Novo mutations in Tourette Syndrome, Animal models for Tourette Syndrome, The neural-immune crosstalk in Tourette syndrome: from immunobiology to epistemology, Functional connectivity in the Gilles de la Tourette Syndrome, and much more. - Includes examines of Gilles de la Tourette Syndrome at behavioral, cognitive, clinical, electrophysiological, molecular and genetic levels - Provides a comprehensive overview of the neurobiological aspects of Gilles de la Tourette Syndrome - Edited and authored by top researchers and clinicians treating Gilles de la Tourette Syndrome
Author:
Publisher: Academic Press
ISBN: 0323910351
Category : Science
Languages : en
Pages : 464
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Book Description
The Neurobiology of the Gilles de la Tourette Syndrome and Chronic Tics, Volume Three reviews historical background and current nosology and guidelines. In addition, it includes an overview of pathophysiology, ranging from its genetic basis and changes in neurochemistry and electrophysiology to widespread neural circuits. Specific chapters cover Tourette syndrome from phenomenology and natural history to neurobiology, Update and Recent progress in the Neurobiology of Tourette Syndrome, Current guidelines and nosology of Tourette syndrome, Neuroimaging applications in Tourette's Syndrome, Clinical and neurodevelopmental brain imaging of Tourette syndrome, Altered Structural Connectivity in Gilles de la Tourette Syndrome, and much more. The last 20?years have seen an exponential growing body of research dedicated to Gilles de la Tourette Syndrome in the understanding of the syndrome's complex genetics and underlying neurobiology. This unprecedented surge in basic and clinical research has resulted in over 3,000 scientific publications. - Examines Gilles de la Tourette Syndrome at behavioral, cognitive, clinical, electrophysiological, molecular and genetic levels - Provides a comprehensive overview of the neurobiological aspects of Gilles de la Tourette Syndrome - Edited and authored by top researchers and clinicians treating the Gilles de la Tourette Syndrome
Author: Davide Martino
Publisher: Oxford University Press
ISBN: 0197543219
Category : Medical
Languages : en
Pages : 577
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Book Description
Tourette syndrome (TS) has become increasingly recognised within society and has gained scientific interest worldwide. Knowledge of its clinical presentation, mechanisms of disease, and available treatment approaches has increased remarkably over the last two decades. Likewise, the way clinicians, teachers, social care workers, and families face the problems manifested by patients with TS is rapidly evolving. Tourette Syndrome, edited by Davide Martino and James F. Leckman, offers a unique opportunity to capture this knowledge advance through a comprehensive and up-to-date overview. Tourette Syndrome covers all the main aspects related to TS, analyzing its complex clinical presentation, the novel viewpoints of causes and mechanisms, state-of-the-art assessment techniques, and the diversity of treatment options. Multidisciplinarity is the main asset of this volume, which represents a source of consultation for a wide audience of professionals, integrated with video tutorials related to particularly complex areas of patient management. Medical and PhD students, as well as post-doctoral scientists, will be able to use the volume as a valuable learning source.
Author: Peristera Paschou
Publisher: Frontiers Media SA
ISBN: 2889453235
Category :
Languages : en
Pages : 324
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Book Description
Gilles de la Tourette Syndrome (TS) is a common, albeit severely under-diagnosed, neuropsychiatric disorder that is caused by a complex genetic basis, interacting with environmental factors. High comorbidity rates with other neurodevelopmental disorders such as attention deficit/hyperactivity disorder and obsessive compulsive disorder raise the intriguing hypothesis of a shared etiological background. Abnormalities of corticostriatal-thalamic-cortical circuits (CSTC) and dysfunction of both dopamine and serotonin neurotransmitter systems are assumed to be associated with TS. Recently, multiple lines of evidence also point towards an important role of additional neurotransmitters such as histamine and glutamate. For a very long time, efforts to elucidate the etiology and pathophysiology of TS have been fragmented and hampered by low statistical power. Finally, after more than two decades of active research aiming to identify the etiology and pathophysiology of TS, we are on the verge of a new era, promising exciting and rapid discoveries in the field. Investigators from around the world, representing multiple disciplines and scientific approaches, are joining their efforts in large-scale initiatives supported both by European Union and US National funding agencies, such as the European-funded EMTICS, TACTICS, and TSGeneSEE consortia, the Marie Curie Initial Training Network TS-EUROTRAIN and the European Society for the Study of TS joining forces with the NIH-funded TSAICG, GGRI, and Tic Genetics consortia. Importantly, all these initiatives are supported by TS patient support and advocacy groups. Multiple resources are being consolidated and coming together to serve the study of TS, including large well-characterized patient cohorts, and specialized epidemiological databases, such as the unique resource of the Netherlands Twin Register. This research topic showcases current large-scale collaborative efforts aiming to elucidate the genetic and neurobiological background of TS, through diverse approaches; from genomewide association studies aiming to identify common variants associated to the disorder to neuroimaging studies and animal models. Furthermore, current approaches on the clinical assessment and management of the disorder are presented. Propelled by the gradual availability of large scale TS cohorts, novel methodologies, and importantly, sheer enthusiasm by multiple researchers working together across different countries, the new era of the neurobiology of TS holds the promise to identify novel targets for improved therapies.
Author: Daniel J. Levitin
Publisher: Penguin
ISBN: 0735246173
Category : Science
Languages : en
Pages : 417
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Book Description
Neuroscientist and New York Times bestselling author of This Is Your Brain on Music Daniel J. Levitin reveals how the deep connections between music and the human brain can be harnessed for healing. Music is perhaps one of humanity’s oldest medicines as well as its most universal: from China to the Ottoman Empire, Europe to Africa and pre-colonial South America, cultures have developed rich traditions for using sound and rhythm to ease suffering, spur healing, and calm the mind. Despite this history, musical therapy has long been considered the remit of ancient practice and alternative medicine, if not outright quackery and pseudoscience. In the last decade, however, an overwhelming body of scientific evidence has emerged that persuasively argues music can offer profoundly effective treatment for a whole host of ailments, from Alzheimer’s to PTSD, depression, pain, and cognitive injury. It is, in short, one of the most potent and remarkably promising new therapies available today. A work of dazzling ideas, cutting-edge research, and joyful celebration of the human mind, I Heard There Was a Secret Chord explores the critical role music has played in human evolution, illuminating how the story of the human brain is inseparable from the creative enterprise of music that has bound cultures together throughout history. Music insinuates itself into our earliest memories; it is intimately connected to our emotional regulation and cognition; its shared rhythms and sounds are essential to our social behaviors. As neuroscientist Daniel J. Levitin demonstrates in this mind-expanding follow-up to This Is Your Brain on Music—which revolutionized our understanding of the neuroscience of song—medical researchers are now finding that these same deep connections can be harnessed to create profound benefits for those both young and old.
Author:
Publisher: Academic Press
ISBN: 0323899447
Category : Science
Languages : en
Pages : 316
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Book Description
Mechanisms of Cell Death and Approaches to Neuroprotection/Disease Modification in Parkinson's Disease explores the results of numerous studies surrounding in vitro and animal model evidence that looks at the impact of a-synucleinopathy on neuronal dysfunction and behavioral impairments, (ii) how research in animal models supports the development of therapeutic strategies, and (iii) how findings in animal models might relate to the disease process in humans. In this book, the author's shed light upon the complex scenario of the mechanisms of cell death and approaches to neuroprotection/disease modification in PD, both in vitro to in vivo. Along with degeneration, the pathological hallmark of PD is the presence of intraneuronal proteinaceous cytoplasmic inclusions, named Lewy Bodies (LB) that invade the whole nervous system as the disease progresses. Several fundamental discoveries have shed light upon the implication of the a-syn protein in the pathogenesis of familial and sporadic forms of PD. Other proteins also accumulate in LB, but a-syn is a major protein component of the pathological landmarks. - Updates on the latest research surrounding Mechanisms of Cell Death in Parkinson's Disease - Includes In vitro and In vivo models of synucleinopathy - Presents therapeutic strategies in Parkinson's Disease
Author: Douglas W. Woods
Publisher: Oxford University Press
ISBN: 019971228X
Category : Psychology
Languages : en
Pages : 81
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Book Description
If you suffer from Tourette Syndrome (TS), or any other chronic motor or vocal tic disorder, you know how difficult it can be to manage your symptoms. You may be taking medication or working with a medical doctor to control your tics. If you are seeking an alternative or adjunctive treatment, you may wish to try the scientifically proven behavior therapy program described in this workbook. Behavior therapy can teach you skills for effectively managing your tics. Designed to be used in conjunction with visits to a qualified mental health professional, this workbook outlines an 11-session treatment package for adults and children with tic disorders. Behavior therapy can teach you skills for effectively managing your tics. Designed to be used in conjunction with visits to a qualified mental health professional, this workbook outlines an 11-session treatment package for adults and children with tic disorders. The goal of this program is not to cure your disorder, but to teach you the best ways to manage it so that you can improve your quality of life and look to the future with optimism. TreatmentsThatWorkTM represents the gold standard of behavioral healthcare interventions! · All programs have been rigorously tested in clinical trials and are backed by years of research · A prestigious scientific advisory board, led by series Editor-In-Chief David H. Barlow, reviews and evaluates each intervention to ensure that it meets the highest standard of evidence so you can be confident that you are using the most effective treatment available to date · Our books are reliable and effective and make it easy for you to provide your clients with the best care available · Our corresponding workbooks contain psychoeducational information, forms and worksheets, and homework assignments to keep clients engaged and motivated · A companion website (www.oup.com/us/ttw) offers downloadable clinical tools and helpful resources · Continuing Education (CE) Credits are now available on select titles in collaboration with PsychoEducational Resources, Inc. (PER)
Author: Cristian Falup-Pecurariu
Publisher: Academic Press
ISBN: 0323851231
Category : Technology & Engineering
Languages : en
Pages : 316
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Book Description
Autonomic dysfunction is one of the most prevalent non-motor symptoms that occurs in Parkinson's disease. Autonomic Dysfunction in Parkinson's Disease provides up to date information on this important topic, which affects quality of life of these patients. This include a large number of domains: orthostatic hypotension, excessive sweating, dry eyes, constipation, weight loss, increased sensitivity to heat and cold, sexual dysfunction. - Provides comprehensive reviews on different topics of autonomic dysfunction in Parkinson's disease - Each chapter covers a specific autonomic symptom: classification, assessment, treatment - Presents the newest information on each autonomic symptom in Parkinson's disease
Author: Michael B. First
Publisher: American Psychiatric Pub
ISBN: 9781585624614
Category : Medical
Languages : en
Pages : 0
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Book Description
The Structured Clinical Interview for DSM-5 --Clinician Version (SCID-5-CV) guides the clinician step-by-step through the DSM-5 diagnostic process. Interview questions are provided conveniently along each corresponding DSM-5 criterion, which aids in rating each as either present or absent. A unique and valuable tool, the SCID-5-CV covers the DSM-5 diagnoses most commonly seen in clinical settings: depressive and bipolar disorders; schizophrenia spectrum and other psychotic disorders; substance use disorders; anxiety disorders (panic disorder, agoraphobia, social anxiety disorder, generalized anxiety disorder); obsessive-compulsive disorder; posttraumatic stress disorder; attention-deficit/hyperactivity disorder; and adjustment disorder. It also screens for 17 additional DSM-5 disorders. Versatile in function, the SCID-5-CV can be used in a variety of ways. For example, it can ensure that all of the major DSM-5 diagnoses are systematically evaluated in adults; characterize a study population in terms of current psychiatric diagnoses; and improve interviewing skills of students in the mental health professions, including psychiatry, psychology, psychiatric social work, and psychiatric nursing. Enhancing the reliability and validity of DSM-5 diagnostic assessments, the SCID-5-CV will serve as an indispensible interview guide.
Author: Harvey S. Singer
Publisher: Academic Press
ISBN: 0124115802
Category : Medical
Languages : en
Pages : 601
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Book Description
Movement Disorders in Childhood, Second Edition, provides the most up-to-date information on the diseases and disorders that affect motor control, an important area of specialization within child neurology. Over the past several decades, advances in genetics, neuroimaging, neurophysiology, and other areas of neuroscience have provided new understanding of the underlying etiologies and mechanisms of these conditions as well as new opportunities for more accurate diagnosis and effective treatment. This new edition builds upon the success of the first edition, with comprehensive scientific and clinical updates of all chapters. In addition, there are new chapters on hereditary spastic paraplegia, quantitative motor assessments, autoimmune disorders, and movement disorders in the developmental neuropsychiatric disorders ADHD, OCD, and autism. Additional materials are provided on the latest in drug treatments, computer based strategies for genetic diagnosis, and helpful videos for phenomenology. - Provides the only current reference specifically focused on childhood movement disorders - Investigates the underlying etiologies and mechanisms of these disorders - Completely revised and updated with new materials and a more disease-oriented approach - New coverage of genetics and movement disorders, immunology and movement disorders, and an introduction to the latest quantitative analysis - New videos of instructive and unusual childhood movement disorders - 2016 BMA Medical Book Awards Highly Commended in Neurology
