The Natural History of the Parkinson's Disease in Early Stages PDF Download
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Author: Benno Schwartz
Publisher: Logos Verlag Berlin GmbH
ISBN: 3832529608
Category : Medical
Languages : en
Pages : 175
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Book Description
237 untreated patients with probable Parkinson's disease could be followed 10 weeks up to 86 months after the first neurological examination. The clinical investigation and the estimation of the severity of the parkinsonian symptoms was done every time according to UPDRS. All patients received cranial computed tomography or MRI of the head, neuropsychological tests, and some of them also SPECT investigation with 123I-Ioflupane (DaTSCAN) or IBZM and/or neurophysiological examinations ( tremor analysis ). The study analysed the appearance, presence and course of the main motor symptoms (bradykinesia, rigidity, tremor, postural instability ) of the Parkinson syndrome, looked for the possible influence upon other motor symptoms, and investigated the presence, course and importance of the non-motor symptoms in the early stages of the disease. There were also examinated the diagnosis algorithmus of the Parkinson's disease in the early stages, the estimation of the stages duration, and the clinical criteria of the therapy initiation.
Author: Benno Schwartz
Publisher: Logos Verlag Berlin GmbH
ISBN: 3832529608
Category : Medical
Languages : en
Pages : 175
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Book Description
237 untreated patients with probable Parkinson's disease could be followed 10 weeks up to 86 months after the first neurological examination. The clinical investigation and the estimation of the severity of the parkinsonian symptoms was done every time according to UPDRS. All patients received cranial computed tomography or MRI of the head, neuropsychological tests, and some of them also SPECT investigation with 123I-Ioflupane (DaTSCAN) or IBZM and/or neurophysiological examinations ( tremor analysis ). The study analysed the appearance, presence and course of the main motor symptoms (bradykinesia, rigidity, tremor, postural instability ) of the Parkinson syndrome, looked for the possible influence upon other motor symptoms, and investigated the presence, course and importance of the non-motor symptoms in the early stages of the disease. There were also examinated the diagnosis algorithmus of the Parkinson's disease in the early stages, the estimation of the stages duration, and the clinical criteria of the therapy initiation.
Author: Jonas H. Ellenberg
Publisher: CRC Press
ISBN: 9780824788230
Category : Medical
Languages : en
Pages : 600
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Book Description
This comprehensive reference provides a detailed overview of current concepts regarding the cause of Parkinson's disease-emphasizing the issues involved in the design, implementation, and analysis of epidemiological studies of parkinsonism.
Author: Cristian Falup-Pecurariu
Publisher: Springer
ISBN: 3709116287
Category : Medical
Languages : en
Pages : 444
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Book Description
This book offers a comprehensive approach to the wide range of movement disorders, an important specialty in the field of neurology, guiding readers from the phenomenology to diagnosis and management. Reflecting the latest developments in the field, it offers a unique summary of this dynamic area by pursuing a uniform approach to movement disorders curricula. Divided into three parts, Movement Disorders Curricula provides an authoritative overview of this growing branch of neurology. The first part presents the basic elements of movement disorders, including descriptions of the anatomy and physiology of the basal ganglia. It also features sections on clinical trials for movement disorders, practical skills, and rating scales. The second and third part examine in detail hypokinetic and hyperkinetic movement disorders, respectively. Equipping readers with the practical and research skills needed in the movement disorders field, the book offers a valuable tool to help them prepare for board examinations on general neurology, as well as for fellowships in movement disorders.
Author: James Parkinson
Publisher:
ISBN:
Category : Parkinson's disease
Languages : en
Pages : 86
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Book Description
Author: Sotirios Parashos
Publisher: Oxford University Press
ISBN: 019931120X
Category : Health & Fitness
Languages : en
Pages : 320
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Book Description
Here is a marvelous guide for anyone affected by Parkinson's disease--patients, caregivers, family members, and friends. Containing the most up-to-date information on the disease, one of the most common neurological disorders, it discusses the available treatments and provides practical advice on how to manage the disease in the long term. Emphasizing life-style adjustments that will provide a better quality of life and moderate the burden for patients and their loved ones, the book answers many questions and clarifies misunderstandings regarding the disease. Written by two experts on Parkinson's disease and a freelance journalist, the book is approachable and easily understandable. Question and answer sections are provided, while "hot topics" are highlighted for easy visibility. The authors have also included true patient stories that will both inspire and instruct, and they have addressed several topics often not mentioned in physician-directed disease management, such as how to talk to family and friends about one's life with Parkinson's.
Author: Ivan Donaldson
Publisher: Oxford University Press
ISBN: 0191502243
Category : Medical
Languages : en
Pages : 1512
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Book Description
This book represents the final work of the late Professor C. David Marsden, who was the most influential figure in the field of movement disorders, in terms of his contributions to both research and clinical practice, in the modern era. It was conceived and written by David Marsden and his colleague at the Institute of Neurology, Prof. Ivan Donaldson. It was their intention that this would be the most comprehensive book on movement disorders and also that it would serve as the 'clinical Bible' for the management of these conditions. It provides a masterly survey of the entire topic, which has been made possible only by vast laboratory and bedside experience. Marsden's Book of Movement Disorders covers the full breadth of movement disorders, from the underlying anatomy and understanding of basal ganglia function to the diagnosis and management of specific movement disorders, including the more common conditions such as Parkinson's Disease through to rare, and very rare conditions such as Niemann-Pick disease. Chapters follow a structured format with historical overviews, definitions, clinical features, differential diagnosis, investigations and treatment covered in a structured way. It is extensively illustrated with many original photographs and diagrams of historical significance. Among these illustrations are still images of some original film clips of some of Dr. Marsden's patients published here for the first time. Comprehensively referenced and updated by experts from the Institute of Neurology at Queen Square, this book is a valuable reference for, not just movement disorder specialists and researchers, but also for clinicians who care for patients with movement disorders.
Author: K. Ray Chaudhuri
Publisher: Oxford University Press, USA
ISBN: 0199684243
Category : Medical
Languages : en
Pages : 517
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Book Description
Patients with Parkinson's disease (PD) are known to suffer from motor symptoms of the disease, but they also experience non-motor symptoms (NMS) that are often present before diagnosis or that inevitably emerge with disease progression. The motor symptoms of Parkinson's disease have been extensively researched, and effective clinical tools for their assessment and treatment have been developed and are readily available. In contrast, researchers have only recently begun to focus on the NMS of Parkinson's Disease, which are poorly recognized and inadequately treated by clinicians. The NMS of PD have a significant impact on patient quality of life and mortality and include neuropsychiatric, sleep-related, autonomic, gastrointestinal, and sensory symptoms. While some NMS can be improved with currently available treatments, others may be more refractory and will require research into novel (non-dopaminergic) drug therapies for the future. Edited by members of the UK Parkinson's Disease Non-Motor Group (PD-NMG) and with contributions from international experts, this new edition summarizes the current understanding of NMS symptoms in Parkinson's disease and points the way towards future research.
Author: Detlev Boison
Publisher: Oxford University Press
ISBN: 0199322295
Category : Medical
Languages : en
Pages : 657
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Book Description
Homeostatic Control of Brain Function offers a broad view of brain health and diverse perspectives for potential treatments, targeting key areas such as mitochondria, the immune system, epigenetic changes, and regulatory molecules such as ions, neuropeptides, and neuromodulators. Loss of homeostasis becomes expressed as a diverse array of neurological disorders. Each disorder has multiple comorbidities - with some crossing over several conditions - and often disease-specific treatments remain elusive. When current pharmacological therapies result in ineffective and inadequate outcomes, therapies to restore and maintain homeostatic functions can help improve brain health, no matter the diagnosis. Employing homeostatic therapies may lead to future cures or treatments that address multiple comorbidities. In an age where brain diseases such as Alzheimer's or Parkinson's are ever present, the incorporation of homeostatic techniques could successfully promote better overall brain health. Key Features include · A focus on the homeostatic controls that significantly depend on the way one lives, eats, and drinks. · Highlights from emerging research in non-pharmaceutical therapies including botanical medications, meditation, diet, and exercise. · Incorporation of homeostatic therapies into existing basic and clinical research paradigms. · Extensive scientific basic and clinical research ranging from molecules to disorders. · Emerging practical information for improving homeostasis. · Examples of homeostatic therapies in preventing and delaying dysfunction. Both editors, Detlev Boison and Susan Masino, bring their unique expertise in homeostatic research to the overall scope of this work. This book is accessible to all with an interest in brain health; scientist, clinician, student, and lay reader alike.
Author: Cristian Falup-Pecurariu
Publisher: Academic Press
ISBN: 0323851231
Category : Technology & Engineering
Languages : en
Pages : 316
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Book Description
Autonomic dysfunction is one of the most prevalent non-motor symptoms that occurs in Parkinson's disease. Autonomic Dysfunction in Parkinson's Disease provides up to date information on this important topic, which affects quality of life of these patients. This include a large number of domains: orthostatic hypotension, excessive sweating, dry eyes, constipation, weight loss, increased sensitivity to heat and cold, sexual dysfunction. - Provides comprehensive reviews on different topics of autonomic dysfunction in Parkinson's disease - Each chapter covers a specific autonomic symptom: classification, assessment, treatment - Presents the newest information on each autonomic symptom in Parkinson's disease
Author: Massimo Filippi
Publisher: Cambridge University Press
ISBN: 1107035945
Category : Medical
Languages : en
Pages : 393
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Book Description
A comprehensive survey of best practice in using diagnostic imaging in acute neurologic conditions. The symptom-based approach guides the choice of the available imaging tools for efficient, accurate, and cost-effective diagnosis. Effective examination algorithms integrate neurological and imaging concepts with the practical demands and constraints of emergency care.
