Biological Weapons Defense

Biological Weapons Defense PDF Author: Luther E. Lindler
Publisher: Springer Science & Business Media
ISBN: 1588291847
Category : History
Languages : en
Pages : 594

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Book Description
The release of nerve gas in the Tokyo subways, the spread of biological weapons, and the anthrax attack of 2001 in the United States demonstrate that not only is the threat of such menacing weapons real, but also that we must urgently prepare to deal with future acts of bioterrorism. In Biological Weapons Defense: Infectious Diseases and Counterbioterrorism, prominent experts in biodefense research-many from the US Army Medical Research Institute of Infectious Diseases-authoritatively delineate the universe of scientific, medical, and legal issues facing the biodefense research community. Regarding medical countermeasures and decontamination, the authors review the facts about both the aerosol route of infection and decontamination processes, and fully describe the pathogenesis and treatment of a variety of established pathogens (anthrax, plague, smallpox, Brucellosis, glanders, and Coxiella burnetii). They also examine how to discover the presence of these agents, or other previously unknown biological weapons, and the ongoing efforts to counter such agents, including proteomic and genomic analysis as a gateway to better diagnostics, therapeutics, vaccinations, genotyping, and forensics. Additional chapters discuss the development and use of technology to identify and characterize these infectious organisms and their emerging threats. Comprehensive and authoritative, Biological Weapons Defense: Infectious Diseases and Counterbioterrorism provides researchers, physicians, and policymakers with a sound basis for understanding not only the diseases caused by these infectious organisms, but also an appreciation of the universe of bioterrorism problems that must be mastered to develop effective countermeasures.

Biological Weapons Defense

Biological Weapons Defense PDF Author: Luther E. Lindler
Publisher: Springer Science & Business Media
ISBN: 1588291847
Category : History
Languages : en
Pages : 594

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Book Description
The release of nerve gas in the Tokyo subways, the spread of biological weapons, and the anthrax attack of 2001 in the United States demonstrate that not only is the threat of such menacing weapons real, but also that we must urgently prepare to deal with future acts of bioterrorism. In Biological Weapons Defense: Infectious Diseases and Counterbioterrorism, prominent experts in biodefense research-many from the US Army Medical Research Institute of Infectious Diseases-authoritatively delineate the universe of scientific, medical, and legal issues facing the biodefense research community. Regarding medical countermeasures and decontamination, the authors review the facts about both the aerosol route of infection and decontamination processes, and fully describe the pathogenesis and treatment of a variety of established pathogens (anthrax, plague, smallpox, Brucellosis, glanders, and Coxiella burnetii). They also examine how to discover the presence of these agents, or other previously unknown biological weapons, and the ongoing efforts to counter such agents, including proteomic and genomic analysis as a gateway to better diagnostics, therapeutics, vaccinations, genotyping, and forensics. Additional chapters discuss the development and use of technology to identify and characterize these infectious organisms and their emerging threats. Comprehensive and authoritative, Biological Weapons Defense: Infectious Diseases and Counterbioterrorism provides researchers, physicians, and policymakers with a sound basis for understanding not only the diseases caused by these infectious organisms, but also an appreciation of the universe of bioterrorism problems that must be mastered to develop effective countermeasures.

Construction and Operation of the National Biodefense Analysis and Countermeasures Center (NBACC) Facility by the Department of Homeland Security at Fort Detrick

Construction and Operation of the National Biodefense Analysis and Countermeasures Center (NBACC) Facility by the Department of Homeland Security at Fort Detrick PDF Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 478

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Book Description


Department of Homeland Security Bioterrorism Risk Assessment

Department of Homeland Security Bioterrorism Risk Assessment PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 0309120284
Category : Political Science
Languages : en
Pages : 172

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Book Description
The mission of Department of Homeland Security Bioterrorism Risk Assessment: A Call for Change, the book published in December 2008, is to independently and scientifically review the methodology that led to the 2006 Department of Homeland Security report, Bioterrorism Risk Assessment (BTRA) and provide a foundation for future updates. This book identifies a number of fundamental concerns with the BTRA of 2006, ranging from mathematical and statistical mistakes that have corrupted results, to unnecessarily complicated probability models and models with fidelity far exceeding existing data, to more basic questions about how terrorist behavior should be modeled. Rather than merely criticizing what was done in the BTRA of 2006, this new NRC book consults outside experts and collects a number of proposed alternatives that could improve DHS's ability to assess potential terrorist behavior as a key element of risk-informed decision making, and it explains these alternatives in the specific context of the BTRA and the bioterrorism threat.

Responsible Research with Biological Select Agents and Toxins

Responsible Research with Biological Select Agents and Toxins PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 030914535X
Category : Political Science
Languages : en
Pages : 188

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Book Description
The effort to understand and combat infectious diseases has, during the centuries, produced many key advances in science and medicine-including the development of vaccines, drugs, and other treatments. A subset of this research is conducted with agents that, like anthrax, not only pose a severe threat to the health of humans, plants, and animals but can also be used for ill-intended purposes. Such agents have been listed by the government as biological select agents and toxins. The 2001 anthrax letter attacks prompted the creation of new regulations aimed at increasing security for research with dangerous pathogens. The outcome of the anthrax letter investigation has raised concern about whether these measures are adequate. Responsible Research with Biological Select Agents and Toxins evaluates both the physical security of select agent laboratories and personnel reliability measures designed to ensure the trustworthiness of those with access to biological select agents and toxins. The book offers a set of guiding principles and recommended changes to minimize security risk and facilitate the productivity of research. The book recommends fostering a culture of trust and responsibility in the laboratory, engaging the community in oversight of the Select Agent Program, and enhancing the operation of the Select Agent Program.

Microbial Forensics

Microbial Forensics PDF Author: Bruce Budowle
Publisher: Academic Press
ISBN: 0123820073
Category : Science
Languages : en
Pages : 753

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Book Description
Microbial Forensics is a rapidly evolving scientific discipline. In the last decade, and particularly due to the anthrax letter attacks in the United States, microbial forensics has become more formalized and has played an increasingly greater role in crime investigations. This has brought renewed interest, development and application of new technologies, and new rules of forensic and policy engagement. It has many applications ranging from biodefense, criminal investigations, providing intelligence information, making society more secure, and helping protect precious resources, particularly human life. A combination of diverse areas is investigated, including the major disciplines of biology, microbiology, medicine, chemistry, physics, statistics, population genetics, and computer science. Microbial Forensics, Second Edition is fully revised and updated and serves as a complete reference of the discipline. It describes the advances, as well as the challenges and opportunities ahead, and will be integral in applying science to help solve future biocrimes. - A collection of microbiology, virology, toxicology and mycology as it relates to forensics, in one reference - New and expanded content to include statistical analysis of forensic data and legal admissibility and the standards of evidence, to name a few - Includes research information and application of that research to crime scene analysis, which will allow practitioners to understand and apply the knowledge to their practice with ease

High-Containment Laboratories

High-Containment Laboratories PDF Author: United States Government Accountability Office
Publisher: Createspace Independent Publishing Platform
ISBN: 9781984167101
Category :
Languages : en
Pages : 104

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Book Description
High-Containment Laboratories: National Strategy for Oversight Is Needed

Management of Animal Care and Use Programs in Research, Education, and Testing

Management of Animal Care and Use Programs in Research, Education, and Testing PDF Author: Robert H. Weichbrod
Publisher: CRC Press
ISBN: 1498748457
Category : Medical
Languages : en
Pages : 917

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Book Description
AAP Prose Award Finalist 2018/19 Management of Animal Care and Use Programs in Research, Education, and Testing, Second Edition is the extensively expanded revision of the popular Management of Laboratory Animal Care and Use Programs book published earlier this century. Following in the footsteps of the first edition, this revision serves as a first line management resource, providing for strong advocacy for advancing quality animal welfare and science worldwide, and continues as a valuable seminal reference for those engaged in all types of programs involving animal care and use. The new edition has more than doubled the number of chapters in the original volume to present a more comprehensive overview of the current breadth and depth of the field with applicability to an international audience. Readers are provided with the latest information and resource and reference material from authors who are noted experts in their field. The book: - Emphasizes the importance of developing a collaborative culture of care within an animal care and use program and provides information about how behavioral management through animal training can play an integral role in a veterinary health program - Provides a new section on Environment and Housing, containing chapters that focus on management considerations of housing and enrichment delineated by species - Expands coverage of regulatory oversight and compliance, assessment, and assurance issues and processes, including a greater discussion of globalization and harmonizing cultural and regulatory issues - Includes more in-depth treatment throughout the book of critical topics in program management, physical plant, animal health, and husbandry. Biomedical research using animals requires administrators and managers who are knowledgeable and highly skilled. They must adapt to the complexity of rapidly-changing technologies, balance research goals with a thorough understanding of regulatory requirements and guidelines, and know how to work with a multi-generational, multi-cultural workforce. This book is the ideal resource for these professionals. It also serves as an indispensable resource text for certification exams and credentialing boards for a multitude of professional societies Co-publishers on the second edition are: ACLAM (American College of Laboratory Animal Medicine); ECLAM (European College of Laboratory Animal Medicine); IACLAM (International Colleges of Laboratory Animal Medicine); JCLAM (Japanese College of Laboratory Animal Medicine); KCLAM (Korean College of Laboratory Animal Medicine); CALAS (Canadian Association of Laboratory Animal Medicine); LAMA (Laboratory Animal Management Association); and IAT (Institute of Animal Technology).

Towards a National Biodefense Strategey [sic]

Towards a National Biodefense Strategey [sic] PDF Author: United States. Congress. House. Select Committee on Homeland Security
Publisher:
ISBN:
Category : History
Languages : en
Pages : 84

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Book Description


Homeland Security

Homeland Security PDF Author: Charles P. Nemeth
Publisher: CRC Press
ISBN: 1466510919
Category : Computers
Languages : en
Pages : 627

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Book Description
Homeland security is a massive enterprise that gets larger by the moment. What was once mostly a TSA/aviation concern has evolved into a multidimensional operation covering a broad array of disciplines. These include critical infrastructure protection, border security, transportation security, intelligence and counterterrorism, emergency management, immigration and naturalization, and public health. Homeland Security: An Introduction to Principles and Practice, Second Edition provides students and practitioners alike with the latest developments on the makeup, organization, and strategic mission of the Department of Homeland Security (DHS). This new edition is fully updated with new laws, regulations, and strategies that reflect changes and developments over the last several years. The book offers unique insights into the various roles of multi-jurisdictional agencies and stakeholders at all levels of government—including law enforcement, the military, the intelligence community, emergency managers, and the private sector. Coverage includes: The history of security threats in the American experience, the events leading up to 9/11, and the formation and evolution of the DHS The legal basis and foundation for the DHS The nature of risk and threat Training and preparatory exercises for homeland security professionals How states and localities can work compatibly with federal policy makers Federal Emergency Management Agency (FEMA) in both the pre- and post-9/11 and post-Katrina world The agencies and entities entrusted with intelligence analysis Issues surrounding border security, immigration, and U.S. citizenship Homeland security practice in the airline, maritime, and mass transit industries—including national, regional, and local rail systems The interplay between public health and homeland security Each chapter contains extensive pedagogy, including learning objectives, informative sidebars, chapter summaries, end-of-chapter questions, web links, and references to aid in comprehension and retention. Homeland Security: An Introduction to Principles and Practice, Second Edition is the only book to provide an objective, balanced perspective on each of the core components that comprise the DHS’s mission and the priorities and challenges that federal and state government agencies continue to face.

Oversight of High-Containment Biological Laboratories

Oversight of High-Containment Biological Laboratories PDF Author: Frank Gottron
Publisher: DIANE Publishing
ISBN: 1437919375
Category : Science
Languages : en
Pages : 33

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Book Description
The fed. gov¿t. responded to the 9/11 terrorist attacks and the subsequent anthrax attacks with increased focus on and funding for biodefense. High-containment labs. (HCL) play a critical role in the biodefense effort, offering the hope of better responses to an attack and a better understanding of the threat posed by bioterrorism. However, they also could increase the risk of a biological attack by serving as a potential source of materials or training. Policymakers have become increasingly interested in the oversight of these facilities following reports of accidents, regulatory noncompliance, and community resistance. A key task for policymakers is to define their goals for enhancing oversight of HCL. Illustrations