The Multiple Inert Gas Elimination Technique (MIGET) PDF Download
Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download The Multiple Inert Gas Elimination Technique (MIGET) PDF full book. Access full book title The Multiple Inert Gas Elimination Technique (MIGET) by Susan R. Hopkins. Download full books in PDF and EPUB format.
Author: Susan R. Hopkins
Publisher: Springer
ISBN: 1493974416
Category : Medical
Languages : en
Pages : 338
Get Book Here
Book Description
The Multiple Inert Gas Elimination Technique (MIGET) is a complex methodology involving specialized gas chromatography and sophisticated mathematics developed in the early 1970’s. Essentially, nobody possesses knowledge of all its elements except for its original developers, and while some practical and theoretical aspects have been published over the years, none have included the level of detail that would be necessary for a potential user to adopt and understand the technique easily. This book is unique in providing a highly detailed, comprehensive technical description of the theory and practice underlying the MIGET to help potential users set up the method and solve problems they may encounter. But it is much more than a reference manual – it is a substantial physiological and mathematical treatise in its own right. It also has a wide applicability – there is extensive discussion of the common biological problem of quantitative inference. The authors took measured whole-lung gas exchange variables, and used mathematical procedures to infer the distribution of ventilation and blood flow from this data. In so doing, they developed novel approaches to answer the question: What are the limits to what can be concluded when inferring the inner workings from the “black box” behavior of a system? The book details the approaches developed, which can be generalized to other similar distributed functions within tissues and organs. They involve engineering approaches such as linear and quadratic programming, and uniquely use mathematical tools with biological constraints to obtain as much information as possible about a “black box” system. Lastly, the book summarizes the hundreds of research papers published by a number of groups over the decades in a way never before attempted in order to marshal the world’s literature on the topic and to provide in one place the wealth of important discoveries, both physiological a nd clinical, enabled by the technique.
Author: Susan R. Hopkins
Publisher: Springer
ISBN: 1493974416
Category : Medical
Languages : en
Pages : 338
Get Book Here
Book Description
The Multiple Inert Gas Elimination Technique (MIGET) is a complex methodology involving specialized gas chromatography and sophisticated mathematics developed in the early 1970’s. Essentially, nobody possesses knowledge of all its elements except for its original developers, and while some practical and theoretical aspects have been published over the years, none have included the level of detail that would be necessary for a potential user to adopt and understand the technique easily. This book is unique in providing a highly detailed, comprehensive technical description of the theory and practice underlying the MIGET to help potential users set up the method and solve problems they may encounter. But it is much more than a reference manual – it is a substantial physiological and mathematical treatise in its own right. It also has a wide applicability – there is extensive discussion of the common biological problem of quantitative inference. The authors took measured whole-lung gas exchange variables, and used mathematical procedures to infer the distribution of ventilation and blood flow from this data. In so doing, they developed novel approaches to answer the question: What are the limits to what can be concluded when inferring the inner workings from the “black box” behavior of a system? The book details the approaches developed, which can be generalized to other similar distributed functions within tissues and organs. They involve engineering approaches such as linear and quadratic programming, and uniquely use mathematical tools with biological constraints to obtain as much information as possible about a “black box” system. Lastly, the book summarizes the hundreds of research papers published by a number of groups over the decades in a way never before attempted in order to marshal the world’s literature on the topic and to provide in one place the wealth of important discoveries, both physiological a nd clinical, enabled by the technique.
Author: Michael R. Pinsky
Publisher: Springer Science & Business Media
ISBN: 3540373632
Category : Medical
Languages : en
Pages : 367
Get Book Here
Book Description
Te practice of intensive care medicine is at the very forefront of titration of treatment andmonitoringresponse. Te substrateofthiscareisthe criticallyill patientwho,by defnition, is at the limits of his or her physiologic reserve. Such patients need immediate, aggressive but balanced life-altering interventions to minimize the detrimental aspects of acute illness and hasten recovery. Treatmentdecisionsandresponsetotherapyareusually assessed by measures of physiologic function, such as assessed by cardio-respiratory monitoring. However, how one uses such information is ofen unclear and rarely supported by prospective clinical trials. In reality, the bedside clinician is forced to rely primarily on physiologic principles in determining the best treatments and response to therapy. However, the physiologic foundation present in practicing physicians is uneven and occasionally supported more by habit or prior training than science. A series of short papers published in Intensive Care Medicine since 2002 under the heading Physiologic Notes attempts to capture the essence of the physiologic perspectives that underpin both our understanding of disease and response to therapy. Tis present volume combines the complete list of these Physiologic Notes up until July 2006 with the ass o cia t ed r e vie w a r tic les o v er t h e s a m e in t er val t ha t a ls o addr ess e d t hes e cen tral issues.
Author: G. Kim Prisk
Publisher: Biota Publishing
ISBN: 1615044515
Category : Science
Languages : en
Pages : 88
Get Book Here
Book Description
The lung receives the entire cardiac output from the right heart and must load oxygen onto and unload carbon dioxide from perfusing blood in the correct amounts to meet the metabolic needs of the body. It does so through the process of passive diffusion. Effective diffusion is accomplished by intricate parallel structures of airways and blood vessels designed to bring ventilation and perfusion together in an appropriate ratio in the same place and at the same time. Gas exchange is determined by the ventilation-perfusion ratio in each of the gas exchange units of the lung. In the normal lung ventilation and perfusion are well matched, and the ventilation-perfusion ratio is remarkably uniform among lung units, such that the partial pressure of oxygen in the blood leaving the pulmonary capillaries is less than 10 Torr lower than that in the alveolar space. In disease, the disruption to ventilation-perfusion matching and to diffusional transport may result in inefficient gas exchange and arterial hypoxemia. This volume covers the basics of pulmonary gas exchange, providing a central understanding of the processes involved, the interactions between the components upon which gas exchange depends, and basic equations of the process.
Author: Seymour Hochheiser
Publisher:
ISBN:
Category : Air
Languages : en
Pages : 62
Get Book Here
Book Description
Author: John F Nunn
Publisher: Elsevier Health Sciences
ISBN: 1483292053
Category : Medical
Languages : en
Pages : 681
Get Book Here
Book Description
Nunn's Applied Respiratory Physiology
Author: John E. Cotes
Publisher: Wiley-Blackwell
ISBN: 9781118597354
Category : Medical
Languages : en
Pages : 0
Get Book Here
Book Description
The seventh edition of the authoritative and comprehensive book on lung function, now revised and updated, continues to cover lung function assessment from first principles including methodology, reference values and interpretation.
Author: Philip M. Hartigan
Publisher: Springer Science & Business Media
ISBN: 0387884939
Category : Medical
Languages : en
Pages : 632
Get Book Here
Book Description
This comprehensive handbook delivers “bottom line,” evidence-based guidance in the practice of thoracic anesthesia. Chapters are short and practical and include actionable technical pearls not available elsewhere. The editor and contributors are academic faculty who work at one of the busiest thoracic surgical programs in North America, and their aim has been to integrate essential concepts with practical decision-making. •Detailed guidance for performing more than 30 thoracic surgical procedures •Relevant surgical insights from a senior thoracic surgeon included for each procedure •Full range of modern thoracic anesthetic challenges covered •Essential foundation concepts digested and simplified •Technical aspects sufficiently detailed to be useful •An efficient resource for skilled generalists and trainees
Author: Philippe Connes
Publisher: IOS Press
ISBN: 1607504960
Category : Medical
Languages : en
Pages : 692
Get Book Here
Book Description
There is no doubt that if the field of exercise physiology is to make further advancements, the various specialized areas must work together in solving the unique and difficult problems of understanding how exercise is initiated, maintained and regulated at many functional levels, and what causes us to quit. Exercise is perhaps the most complex of physiological functions, requiring the coordinated, integrated activation of essentially every cell, tissue and organ in the body. Such activation is known to take place at all levels - from molecular to systemic. Focusing on important issues addressed at cellular and systemic levels, this handbook presents state-of-the-art research in the field of exercise physiology. Each chapter serves as a comprehensive resource that will stimulate and challenge discussion in advanced students, researchers, physiologists, medical doctors and practitioners. Authored by respected exercise physiologists from nineteen countries, each chapter has been significantly updated to provide up-to-date coverage of the topics and to offer complete descriptions of the many facets of the most physiological responses from a cellular to an integrative approach within individual body systems in normal and disease states and includes some chapters that are rarely addressed in exercise physiology books, such as the influence of exercise on endothelium, vasomomotor control mechanisms, coagulation, immune function and rheological properties of blood, and their influence on hemodynamics. This book represents the first iteration to provide such a work. Normal exercise responses divided into muscle function, bioenergetics, and respiratory, cardiac and blood/vascular function; Fitness, training, exercise testing and limits to exercise; Exercise responses in different environments; Beneficial effects of exercise rehabilitation on ageing and in the prevention and treatment of disease states; Rarely addressed issues such as the influence of exercise on endothelium, vasomotor control mechanisms, coagulation, immune function and rheological properties of blood and their influence on hemodynamics. IOS Press is an international science, technical and medical publisher of high-quality books for academics, scientists, and professionals in all fields. Some of the areas we publish in: -Biomedicine -Oncology -Artificial intelligence -Databases and information systems -Maritime engineering -Nanotechnology -Geoengineering -All aspects of physics -E-governance -E-commerce -The knowledge economy -Urban studies -Arms control -Understanding and responding to terrorism -Medical informatics -Computer Sciences
Author: A. Frederick Collins
Publisher: anboco
ISBN: 3736407920
Category : Fiction
Languages : en
Pages : 314
Get Book Here
Book Description
Before delving into the mysteries of receiving and sending messages without wires, a word as to the history of the art and its present day applications may be of service. While popular interest in the subject has gone forward by leaps and bounds within the last two or three years, it has been a matter of scientific experiment for more than a quarter of a century. The wireless telegraph was invented by William Marconi, at Bologna, Italy, in 1896, and in his first experiments he sent dot and dash signals to a distance of 200 or 300 feet. The wireless telephone was invented by the author of this book at Narberth, Penn., in 1899, and in his first experiments the human voice was transmitted to a distance of three blocks. The first vital experiments that led up to the invention of the wireless telegraph were made by Heinrich Hertz, of Germany, in 1888 when he showed that the spark of an induction coil set up electric oscillations in an open circuit, and that the energy of these waves was, in turn, sent out in the form of electric waves. He also showed how they could be received at a distance by means of a ring detector, which he called a resonator.
Author: Michael R. Pinsky
Publisher: Springer Science & Business Media
ISBN: 3642282709
Category : Medical
Languages : en
Pages : 430
Get Book Here
Book Description
The two previous editions of Applied Physiology in Intensive Care Medicine proved extremely successful, and the book has now been revised and split into two volumes to enhance ease of use. This first volume comprises three elements -- "physiological notes," “technical notes,” and seminal studies. The physiological notes concisely and clearly capture the essence of the physiological perspectives underpinning our understanding of disease and response to therapy. The technical notes then succinctly explain some of the basics of “how to” in this technology-centered field of critical care medicine. Finally, a number of seminal studies are provided on diverse topics in intensive care. Applied Physiology in Intensive Care, written by some of the most renowned experts in the field, is an up-to-date compendium of practical bedside knowledge that will serve the clinician as an invaluable reference source on key issues regularly confronted in everyday practice.
