Molecular and Cellular Biology of Pathogenic Trypanosomatids

Molecular and Cellular Biology of Pathogenic Trypanosomatids PDF Author: Marcelo Santos da Silva
Publisher: Bentham Science Publishers
ISBN: 1681084058
Category : Medical
Languages : en
Pages : 612

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Book Description
Frontiers in Parasitology is an Ebook series devoted to publishing the latest and the most important advances in parasitology. Eminent scientists present reviews on the microbiology, cytology, epidemiology, genomics, and molecular biology of microbial parasites and their associated infections. Additionally, the series also gives information about new diagnostic and therapeutic protocols. The Ebook series is essential reading to all scientists involved in studying harmful microbes and their impact on human health.

Molecular and Cellular Biology of Pathogenic Trypanosomatids

Molecular and Cellular Biology of Pathogenic Trypanosomatids PDF Author: Marcelo Santos da Silva
Publisher: Bentham Science Publishers
ISBN: 1681084058
Category : Medical
Languages : en
Pages : 612

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Book Description
Frontiers in Parasitology is an Ebook series devoted to publishing the latest and the most important advances in parasitology. Eminent scientists present reviews on the microbiology, cytology, epidemiology, genomics, and molecular biology of microbial parasites and their associated infections. Additionally, the series also gives information about new diagnostic and therapeutic protocols. The Ebook series is essential reading to all scientists involved in studying harmful microbes and their impact on human health.

The Molecular Epidemiology of Trypanosoma Cruzi Infection in Wild and Domestic Transmission Cycles, with Special Emphasis on Multilocus Microsatellite Analysis

The Molecular Epidemiology of Trypanosoma Cruzi Infection in Wild and Domestic Transmission Cycles, with Special Emphasis on Multilocus Microsatellite Analysis PDF Author:
Publisher:
ISBN:
Category :
Languages : en
Pages :

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Book Description


Trypanosomiasis and Leishmaniasis

Trypanosomiasis and Leishmaniasis PDF Author: Geoff Hide
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 392

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Book Description
Trypanosomiasis and Leishmaniasis are related diseases caused by single celled organisms (protozoa) transmitted by insects. Between them, these diseases are responsible for much suffering among humans and livestock and so a greater understanding of their biology is a vital part of the campaign to control them. Modern molecular techniques available for use in understanding the control of these diseases are becoming more sophisticated and are increasingly becoming universally applicable to a wide variety of diseases. This book brings together the research approaches that are used interchangeably to understand both Trypanosomiasis and Leishmaniasis. Examples of such fruitful integration can be seen in a number of research areas: genome mapping, molecular and population genetic approaches to epidemiology, studies on polyamine metabolism and possible targets for rational drug design, studies on cellular signalling as a route to understanding host-parasite interactions and studies on chemotherapy and drug resistance. There are also chapters that consider those features that are unique to either Trypanosomiasis or Leishmaniasis. Thus a broad overview of the biology of each disease from the molecular level right up to the whole animal is provided. Contributors come from the leading research groups working on these diseases and include clinicians, laboratory based researchers and social scientists. The book provides an up-to-date summary of the advances in the understanding of these diseases that have come about through the use of modern technologies. By presenting an integration of research into both Trypanosomiasis and Leishmaniasis this book provides an innovative contribution to the literature in this area. It is important reading for all parasitologists, pharmacologists, epidemiologists and clinicians working with these organisms. It is also a useful resource for veterinarians, public health workers, policy makers and social scientists concerned with Trypanosomiasis or Leishmaniasis.

Molecular Epidemiology of Trypanosoma (Herpetosoma) Rangeli (Kinetoplastida: Trypanosomatidae) in Ecuador, South America, and Study of the Parasite Cell Invasion Mechanism in Vitro

Molecular Epidemiology of Trypanosoma (Herpetosoma) Rangeli (Kinetoplastida: Trypanosomatidae) in Ecuador, South America, and Study of the Parasite Cell Invasion Mechanism in Vitro PDF Author: Segundo Mauricio Lascano
Publisher:
ISBN:
Category : Cellular immunity
Languages : en
Pages :

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Book Description


Research Priorities for Chagas Disease Human African Trypanosomiasis and Leishmaniasis

Research Priorities for Chagas Disease Human African Trypanosomiasis and Leishmaniasis PDF Author: World Health Organization
Publisher:
ISBN: 9789240689992
Category : Electronic books
Languages : en
Pages : 0

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Book Description
The Disease Reference Group on Chagas Disease Human AfricanTrypanosomiasis and Leishmaniasis (DRG3) was part of an independent thinktankof international experts established by the Special Programme for Researchand Training in Tropical Diseases (TDR) to identify key research prioritiesthrough systematic review of research evidence and input from stakeholders. These three distinct insect-borne diseases while caused by related kinetoplastidprotozoan pathogens have dissimilar geographical distributions a reflection oftheir different insect vectors and range of vector contact with humans. Thedisease.

New Frontiers of Molecular Epidemiology of Infectious Diseases

New Frontiers of Molecular Epidemiology of Infectious Diseases PDF Author: Serge Morand
Publisher: Springer Science & Business Media
ISBN: 9400721145
Category : Medical
Languages : en
Pages : 335

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Book Description
Molecular epidemiology has recently broaden its focuses due to the development of molecular tools but also by incorporating advances of other fields such as mathematical epidemiology, molecular ecology, population genetics and evolution. Facing new risks of emerging and re-emerging infectious diseases that are threats for humans and their livestock, the objectives of molecular epidemiology include: - the development of molecular tools, genotyping and gene expression - the incorporation of concepts and results of population genetics of infectious diseases - the integration of recent advances in theoretical epidemiology and evolutionary ecology of diseases - a better understanding of transmission for the development of risk factors analyses. This book will demonstrate how the latest developments in molecular tools and in epidemiology can be integrated with studies of host-pathogen interactions. Besides a strong theoretical component, there will also be an emphasis on applications in the fields of epidemiology, public health, veterinary medicine, and health ecology. Students and researchers in the fields of epidemiology, animal and human health, evolutionary ecology, parasitology are the main potential readers of the book, as well as a broader audience from veterinary medicine and conservation.

American Trypanosomiasis

American Trypanosomiasis PDF Author: Jenny Telleria
Publisher: Elsevier
ISBN: 0123848776
Category : Medical
Languages : en
Pages : 871

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Book Description
Chagas disease causes severe socioeconomic impact and a high medical cost in Latin America. WHO and the World Bank consider Chagas disease as the fourth most transmittable disease to have a major impact on public health in Latin America: 120 million persons are potentially exposed, 16 to 18 million of whom are presently infected, causing 45,000 to 50,000 deaths per year. It has been calculated that approximately 2.4 million potential working years are lost because of incapacity and mortality due to the disease, for an annual cost estimated at 20 billion Euros. American Trypanosomiasis provides a comprehensive overview of Chagas disease and discusses the latest discoveries concerning the three elements that compose the transmission chain of the disease: - The host: human and mammalian reservoirs - The insect vectors: domestic and sylvatic vectors - The causative parasite: Trypanosoma cruzi - Informs and updates on all the latest developments in the field - Contributions from leading authorities and industry experts

Drug Resistance in Leishmania Parasites

Drug Resistance in Leishmania Parasites PDF Author: Alicia Ponte-Sucre
Publisher: Springer Science & Business Media
ISBN: 3709111250
Category : Medical
Languages : en
Pages : 458

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Book Description
One of the main problems concerning therapeutic tools for the treatment of parasitic diseases, including leishmaniasis, is that some field parasites are naturally resistant to the classical drugs; additionally, current therapies may select parasites prone to be resistant to the applied drugs. These features are (at least partially) responsible for the disappointing persistence of the disease and resultant deaths worldwide. This book provides a comprehensive view of the pathology of the disease itself, and of parasitic drug resistance, its molecular basis, consequences and possible treatments. Scientists both from academic fields and from the industry involved in biomedical research and drug design, will find in this book a valuable and fundamental guide that conveys the knowledge needed to understand and to improve the success in combating this disease worldwide.

The Trypanosomiases

The Trypanosomiases PDF Author: Ian Maudlin
Publisher: CABI
ISBN: 9780851990347
Category : Medical
Languages : en
Pages : 644

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Book Description
This state-of-the-art reference book includes comprehensive coverage of the biology and control of African, Asian and South American trypanosomiasis ("sleeping sickness") in man and animals. It describes recent research developments in the biology and molecular biology of trypanosomes (the protozoan parasite) and their vectors, and methods in diagnosis and control, such as trapping tsetse fly vectors. Different sections of the book are devoted to biology of trypanosomes, vector biology, epidemiology and diagnosis, pathogenesis, disease impact, chemotherapy and disease control, and vector control. The book contains contributions from leading experts from Europe, North and South America, and Africa.

Remote Sensing and Geographical Information Systems in Epidemiology

Remote Sensing and Geographical Information Systems in Epidemiology PDF Author: S.I. Hay
Publisher: Elsevier
ISBN: 9780123335609
Category : Medical
Languages : en
Pages : 414

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Book Description
Global problems require global information, which satellites can now provide. With ever more sophisticated control methods being developed for infectious diseases, our ability to map spatial and temporal variation in risk is more important than ever. Only then may we plan control campaigns and deliver novel interventions and remedies where the need is greatest, and sustainable success is most likely. This book presents a comprehensive guide to using the very latest methods of surveillance from satellites, including analysing spatial data within geographical information systems, interpreting complex biological patterns, and predicting risk both today and as it may change in the future. Of all infectious disease systems, those that involve free-living invertebrate vectors or intermediate hosts are most susceptible to changing environmental conditions, and have hitherto received most attention from the marriage of analytical biology with this new space technology. Accordingly, this volume presents detailed case studies on malaria, African trypanosomiasis (sleeping sickness), tick-borne infections and helminths (worms). For those who are unfamiliar with this science, and unsure how to start, the book ends with a chapter of practical advice on where to seek hands-on instruction. The lessons to be learned from these studies are applicable to many other epidemiological and ecological problems that face us today, most significantly the preservation of the world's biodiversity. Only book to provide a synthesis of complex biology, quantitative analysis, space technology and practical applications, focused on solving real epidemiological problems on a global scale Broad scope, with methods relevant to subjects ranging from biodiversity to public health Practical advice on relevant courses 24 pages of colour plates