An Evaluation of Beta-blockers, Calcium Antagonists, Nitrates, and Alternative Therapies for Stable Angina

An Evaluation of Beta-blockers, Calcium Antagonists, Nitrates, and Alternative Therapies for Stable Angina PDF Author: Paul A. Heidenreich
Publisher: Agency for Healthcare Research & Quality
ISBN:
Category : Medical
Languages : en
Pages : 140

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Book Description

An Evaluation of Beta-blockers, Calcium Antagonists, Nitrates, and Alternative Therapies for Stable Angina

An Evaluation of Beta-blockers, Calcium Antagonists, Nitrates, and Alternative Therapies for Stable Angina PDF Author: Paul A. Heidenreich
Publisher: Agency for Healthcare Research & Quality
ISBN:
Category : Medical
Languages : en
Pages : 140

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Book Description


The Evaluation of Beta Blocker and Calcium Antagonist Drugs

The Evaluation of Beta Blocker and Calcium Antagonist Drugs PDF Author: Joel Morganroth
Publisher:
ISBN: 9789024723362
Category :
Languages : en
Pages : 410

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Book Description


The Evaluation of Beta Blocker and Calcium Antagonist Drugs

The Evaluation of Beta Blocker and Calcium Antagonist Drugs PDF Author: Joel Morganroth
Publisher:
ISBN:
Category :
Languages : en
Pages :

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The Evaluation of Beat Blocker and Calcium Antagonist Drugs

The Evaluation of Beat Blocker and Calcium Antagonist Drugs PDF Author: J. Morganroth
Publisher: Springer Science & Business Media
ISBN: 9400975619
Category : Medical
Languages : en
Pages : 409

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Book Description
With the beginning of the 1980's it was becoming increasingly evident that the lack of approval of new cardiovascular agents for use by clinicians in the United States for the treatment of cardiovascular disorders was becoming a problem. Patients requiring medical therapy for hypertension, angina pectoris, arrhythmias, congestive heart failure, and vasospastic disorders of the coronary arteries could receive in the United States only a small number of the drugs available to physicians in the rest of the world. In fact, as the 1980's began, there was only one available beta blocking agent released by The Food and Drug Administration; and even as of this writing, no oral calcium antagonist agent. This lag, in part, has been due to the confusion of proper and expeditious methods to define safety and efficacy of such agents so that the United States regulatory agency (Food and Drug Administration) could approve the use of such agents by clinicians. The vast number of new beta blocker and calcium antagonist agents being developed, as well as the long-term use abroad of many new drugs, has raised important questions as to how relative safety and efficacy of such agents can be determined to facilitate availability in the United States.

Meta-Analysis, Decision Analysis, and Cost-Effectiveness Analysis

Meta-Analysis, Decision Analysis, and Cost-Effectiveness Analysis PDF Author: Diana B. Petitti
Publisher: OUP USA
ISBN: 0195133641
Category : Language Arts & Disciplines
Languages : en
Pages : 319

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Book Description
Public health and in health policy courses at the undergraduate and graduate level.

Coronary Microvascular Dysfunction

Coronary Microvascular Dysfunction PDF Author: Filippo Crea
Publisher: Springer Science & Business Media
ISBN: 8847053676
Category : Medical
Languages : en
Pages : 263

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Book Description
In the past two decades a number of studies have shown that abnormalities in the function and structure of coronary microcirculation can be detected in several cardiovascular diseases. On the basis of the clinical setting in which it occurs, coronary microvascular dysfunction (CMD) can be classified into four types: CMD in the absence of any other cardiac disease; CMD in myocardial diseases; CMD in obstructive epicardial coronary artery disease; and iatrogenic CMD. In some instances CMD represents an epiphenomenon, whereas in others it represents an important marker of risk or may contribute to the pathogenesis of myocardial ischemia, thus becoming a possible therapeutic target. This book provides an update on coronary physiology and a systematic assessment of microvascular abnormalities in cardiovascular diseases, in the hope that it will assist clinicians in prevention, detection and management of CMD in their everyday activity.

Report of the Joint National Committee on Detection, Evaluation, and Treatment of High Blood Pressure

Report of the Joint National Committee on Detection, Evaluation, and Treatment of High Blood Pressure PDF Author: Joint National Committee on Detection, Evaluation, and Treatment of High Blood Pressure
Publisher:
ISBN:
Category : Hypertension
Languages : en
Pages : 20

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Book Description


Emergency Cardiology Second Edition

Emergency Cardiology Second Edition PDF Author: Karim Ratib
Publisher: CRC Press
ISBN: 0340974222
Category : Medical
Languages : en
Pages : 290

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Book Description
This fully revised and updated second edition of Emergency Cardiology offers highly practical advice on the diagnosis and management of acute cardiac conditions. Throughout the book the authors employ an evidence-based approach to clinical practice, and provide detailed guidance for day-to-day practice in a wider variety of settings - from the emergency department to intensive care and the cardiac ward. Provides essential advice for the rapid diagnosis and management of cardiac emergencies - both common and more rare. Includes evidence-based guidelines and the results of the most groundbreaking clinical trials Practical format pocket-sized format Authored by four cardiologists with extensive experience in the emergency setting Emergency Cardiology, Second Edition is an essential purchase for junior doctors, emergency department staff, trainees in cardiology and specialist nurses.

Heart and Toxins

Heart and Toxins PDF Author: Dr. Meenakshisundaram Sundaram Ramachandran
Publisher: Elsevier
ISBN: 0124165990
Category : Science
Languages : en
Pages : 668

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Book Description
The Heart and Toxins brings together global experts to provide the latest information and clinical trials that make the connection between genetic susceptibility, gene expression, and environmental factors in cardiovascular diseases. This unique reference, edited by renowned cardiologist Meenakshi Sundaram Ramachandran, solves the problem of managing multiple clinical cases of cardiovascular toxicity. It allows connections to be made between research, diagnosis, and treatment to avoid higher morbidity and mortality rates as a result of cardiovascular toxicity. - Structured to bring together exploration into the epidemiology, molecular mechanism, pathogenesis, environmental factors and management in cardiovascular toxins - Included various topics on cardiovascular toxins such as plant, chemical, animal, nanomaterial and marine biology induced cardiac damage – which are new ideas discussed in detail - Comprehensive chapters on the cardiovascular toxicity from drugs, radiotherapy and radiological imaging - Enables you to manage multiple clinical cases of cardiovascular toxicity - Outlined conclusions at the end of each chapter providing "key learning points to help you organize the chapter's details without losing insight

J Wave Syndromes

J Wave Syndromes PDF Author: Charles Antzelevitch
Publisher: Springer
ISBN: 3319315781
Category : Medical
Languages : en
Pages : 342

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Book Description
This book delineates the state of the art of the diagnosis and treatment of J wave syndromes, as well as where future research needs to be directed. It covers basic science, translational and clinical aspects of these syndromes. The authors are leading experts in their respective fields, who have contributed prominently to the literature concerning these topics. J wave syndromes are one of the hottest topics in cardiology today. Cardiac arrhythmias associated with Brugada syndrome (BrS) or an early repolarization (ER) pattern in the inferior or infero-lateral ECG leads are thought to be mechanistically linked to accentuation of transient outward current (Ito)-mediated J waves. Although BrS and ER syndrome (ERS) differ with respect to magnitude and lead location of abnormal J waves, they are thought to represent a continuous spectrum of phenotypic expression termed J wave syndromes. ERS is divided into three subtypes with the most severe, Type 3, displaying an ER pattern globally in the inferior, lateral and right precordial leads. BrS has been linked to mutations in 19 different genes, whereas ERS has been associated with mutations in 7 different genes. There is a great deal of confusion as to how to properly diagnose and treat the J wave syndromes as well as confusion about the underlying mechanisms. The demonstration of successful epicardial ablation of BrS has provided new therapeutic options for the management of this syndrome for which treatment alternatives are currently very limited, particularly in the case of electrical storms caused by otherwise uncontrollable recurrent VT/VF. An early repolarization pattern is observed in 2-5% of the US population. While it is clear that the vast majority of individuals exhibiting an ER pattern are not at risk for sudden cardiac death, the challenge moving forward is to identify those individuals who truly are at risk and to design safe and effective treatments.