The Effect of Solvent on Matrix-assisted Laser Desorption Ionization Mass Spectrometry

The Effect of Solvent on Matrix-assisted Laser Desorption Ionization Mass Spectrometry PDF Author: Karen Kay Campo
Publisher:
ISBN:
Category :
Languages : en
Pages : 156

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The Effect of Solvent on Matrix-assisted Laser Desorption Ionization Mass Spectrometry

The Effect of Solvent on Matrix-assisted Laser Desorption Ionization Mass Spectrometry PDF Author: Karen Kay Campo
Publisher:
ISBN:
Category :
Languages : en
Pages : 156

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Matrix-assisted Laser Desorption Ionization (MALDI) Time-of-flight Mass Spectrometry (TOFMS) for Direct Analysis of Bioactive Peptide and Protein

Matrix-assisted Laser Desorption Ionization (MALDI) Time-of-flight Mass Spectrometry (TOFMS) for Direct Analysis of Bioactive Peptide and Protein PDF Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 13

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Book Description
The overall goal of this research was to develop a matrix assisted time-of-flight mass spectrometry (MALDI) method of mixture analysis based on time-lag focusing matrix-assisted MALDI (MALDI-TOFMS). The specific objectives were to develop sample/matrix preparation methods for mixture analysis and to demonstrate the overall analytical performance of the MALDI method for mixture analysis. This report describes and presents results of this research, including direct analysis of peptide and protein mixtures by MALDI-TOFMS. A two-layer sample preparation method is described as very effective for analyzing complex mixtures. In this method, the first layer on the MALDI probe is the densely packed matrix microcrystals formed by fast solvent evaporation of a matrix solution. A mixture solution containing both matrix and sample is then deposited onto the first layer to form uniform analyte/matrix micro-co-crystals. The effect of solvent conditions for preparing the second-layer solution is discussed.

Mass Spectrometry of Polymers

Mass Spectrometry of Polymers PDF Author: Giorgio Montaudo
Publisher: CRC Press
ISBN: 1420037757
Category : Science
Languages : en
Pages : 601

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Book Description
Mass Spectrometry (MS) has rapidly become an indispensable tool in polymer analysis, and modern MS today complements in many ways the structural data provided by Nuclear Magnetic Resonance (NMR) and Infrared (IR) methods. Recent advances have sparked a growing interest in this field and established a need for a summary of progress made and results

Analysis of Complex Biological Mixtures by Matrix-assisted Laser Desorption/ionization Mass Spectrometry

Analysis of Complex Biological Mixtures by Matrix-assisted Laser Desorption/ionization Mass Spectrometry PDF Author: Xiaoli Liang
Publisher:
ISBN:
Category :
Languages : en
Pages : 318

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MALDI MS

MALDI MS PDF Author: Franz Hillenkamp
Publisher: John Wiley & Sons
ISBN: 3527333312
Category : Science
Languages : en
Pages : 0

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Book Description
This authoritative book on MALDI MS, now finally available in its second edition and edited by one of its inventors, gives an in-depth description of the many different applications, along with a detailed discussion of the technology itself. Thoroughly updated and expanded, with contributions from key players in the field, this unique book provides a comprehensive overview of MALDI MS along with its possibilities and limitations. The initial chapters deal with the technology and the instrumental setup, followed by chapters on the use of MALDI MS in protein research (including proteomics), genomics, glycomics and lipidomics. The option of MALDI-MS for the analysis of polymers and small molecules are also covered in separate chapters, while new to this edition is a section devoted to the interplay of MALDI MS and bioinformatics. A much-needed practical and educational asset for individuals, academic institutions and companies in the field of bioanalytics.

Mass Spectrometry of Proteins and Peptides

Mass Spectrometry of Proteins and Peptides PDF Author: John R. Chapman
Publisher: Springer Science & Business Media
ISBN: 1592590454
Category : Science
Languages : en
Pages : 539

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Book Description
Little more than three years down the line and I am already writing the Preface to a second volume to follow Protein and Peptide Analysis by Mass . What has happened in between these times to make this second venture worthwhile? New types of mass spectrometric instrumentation have appeared so that new techniques have become possible and existing techniques have become much more feasible. More particularly, however, the newer ionization te- niques, introduced for the analysis of high molecular weight materials, have now been thoroughly used and studied. As a result, there has been an en- mous improvement in the associated sample handling technology so that these methods are now routinely applied to much smaller sample amounts as well as to more intractable samples. Again, this particular community of mass spectrometry users has both increased in number and diversified. And, riding this wave of acceptance, leaders in the field have set their sights on more complex problems: molecular interaction, ion structures, quantitation, and kinetics are just a few of the newer areas reported in Mass Spectrometry of Proteins and Peptides. As with the first volume, one purpose of this collection, Mass Spectr- etry of Proteins and Peptides, is to show the reader what can be done by the application of mass spectrometry, and perhaps even to encourage the reader to venture down new paths.

Fundamental Studies of Matrix-assisted Laser Desorption Ionization Mass Spectrometry

Fundamental Studies of Matrix-assisted Laser Desorption Ionization Mass Spectrometry PDF Author: Lisa Michelle Preston-Schaffter
Publisher:
ISBN:
Category :
Languages : en
Pages : 191

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Methodological Advances of MALDI Mass Spectrometry-Based Techniques in Organic and Biomedical Analysis

Methodological Advances of MALDI Mass Spectrometry-Based Techniques in Organic and Biomedical Analysis PDF Author: Cheng Guo
Publisher: Frontiers Media SA
ISBN: 2889764362
Category : Science
Languages : en
Pages : 120

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MALDI Mass Spectrometry Imaging

MALDI Mass Spectrometry Imaging PDF Author: Tiffany Siegel Porta
Publisher: Royal Society of Chemistry
ISBN: 1839162414
Category : Science
Languages : en
Pages : 541

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Book Description
This book gathers knowledge about matrix-assisted laser desorption ionisation (MALDI) mass spectrometry imaging for postgraduate and professional researchers in academia and in industry where it has direct application to clinical research.

MALDI Mass Spectrometry for Synthetic Polymer Analysis

MALDI Mass Spectrometry for Synthetic Polymer Analysis PDF Author: Liang Li
Publisher: John Wiley & Sons
ISBN: 0470567228
Category : Science
Languages : en
Pages : 325

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Book Description
Principles and Practices of Polymer Mass Spectrometry helps readers acquire the skills necessary for selecting the optimal methods, handling samples, analyzing the data, and interpreting the results of the mass spectrometry of polymers. This guide describes the principles of polymer MS and best practices in polymer characterization. It discusses different approaches, including MALDI, ESI, TOF MS, and FT-MS. It provides a guide to developing appropriate sample preparation protocols for different polymers. Complete with examples of applications and experiments, this is an excellent reference for scientists, researchers, graduate students, and others.