Author: Janice E. Chambers
Publisher: Elsevier
ISBN: 0080917267
Category : Medical
Languages : en
Pages : 462
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Book Description
This volume pulls together a wealth of up-to-date information on the toxicology of this diverse and ubiquitous class of insecticides. Leading experts review the reactivity of organophosphorus compounds with cholinesterase, as well as their metabolism and biological effects on humans and other nontarget organisms. The book not only covers the anticholinesterase actions of organophosphates, but also other, presumably independent, effects, such as teratogenicity, delayed neuropathy, immunotoxicity, and behavioral toxicity. - Offers crucial overviews of chemical and biochemical reactivity and biological responsiveness of mainly nontarget organisms - Reviews new developments in assessment of metabolism and disposition of organophosphorus compounds - Examines organophosphorus compound-induced toxicity mediated by mechanisms other than inhibition of acetylcholinesterase - Covers new research on differences in toxicity induced by the variety of organophosphorus - Analyzes current controversies on the relevance of certain biochemical parameters in actual organophosphate toxicity in vivo
Author: Viktor Iaroshenko
Publisher: John Wiley & Sons
ISBN: 3527335722
Category : Science
Languages : en
Pages : 586
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Book Description
Filling the gap for an up-to-date reference that presents the field of organophosphorus chemistry in a comprehensive and clearly structured way, this one-stop source covers the chemistry, properties, and applications from life science and medicine. Divided into two parts, the first presents the chemistry of various phosphorus-containing compounds and their synthesis, including ylides, acids, and heterocycles. The second part then goes on to look at applications in life science and bioorganic chemistry. Last but not least, such important practical aspects as 31P-NMR and protecting strategies for these compounds are presented. For organic, bioinorganic, and medicinal chemists, as well as those working on organometallics, and for materials scientists. The book, a contributed work, features a team of renowned scientists from around the world whose expertise spans the many aspects of modern organophosphorus chemistry.
Author: Christa Fest
Publisher: Springer Science & Business Media
ISBN: 3642978762
Category : Science
Languages : en
Pages : 346
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Book Description
Our intention has been to provide a short introduction to the chemistry and mode of action of insecticidal phosphoric acid compounds, with particular reference to the relationship between structure and activity. The yearly production of these pesticides is now approaching 100,000 tons and thus offers an important example of applied research. If, however, one examines the historical develop ment of these compounds, it is apparent that this was preceded by a hundred years of pure chemistry of phosphorus. The utility of the phosphoric acid pesticides is undisputed today - and furthermore it can be expected that they will solve many of the world's nutritional problems" yet from this field of applied research many paths are now leading back into basic research in chemistry, biochemistry, biology and toxicology etc. This clearly illustrates the problem of attempting to define pure and applied research. Originally, this book was conceived for students of chemistry who, on completion of their study, were uncertain about the place of applied research in industry but it was soon clear that such material, when supplemented with further data, would serve as an introduction to the field of pesticidal phosphoric acid compounds for many technicians, officials and scientists who, in various authorities in agriculture, in chemical and biological research, are concerned with the problems of crop protection and more recently with questions of pollution of the environ ment.
Author: Louis D. Quin
Publisher: John Wiley & Sons
ISBN: 9780471318248
Category : Science
Languages : en
Pages : 416
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Book Description
Die organische Chemie des Phosphors - ein großes, äußerst lebendiges Forschungsfeld - umfaßt sowohl Verbindungen mit Kohlenstoff-Phosphor-Bindungen als auch organische Ester anorganischer Phosphorsäuren. Dieser Band behandelt die meisten phosphorhaltigen funktionellen Gruppen und daneben aktuelle Fragen wie z.B. ungewöhnliche Koordinationszustände, Heterocyclen, Anwendungen der 31P-NMR und andere spektroskopische Verfahren. Soweit bekannt, werden auch elektronische Reaktionsmechanismen und reaktive Intermediate diskutiert. Mit zahlreichen Literaturhinweisen! (03/00)
Author: David W Allen
Publisher: Royal Society of Chemistry
ISBN: 1847554504
Category : Science
Languages : en
Pages : 352
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Book Description
Organophosphorus Chemistry provides a comprehensive annual review of the literature. Coverage includes phosphines and their chalcogenides, phosphonium salts, low coordination number phosphorus compounds, penta- and hexa-coordinated compounds, tervalent phosphorus acids, nucleotides and nucleic acids, ylides and related compounds, and phosphazenes. The series will be of value to research workers in universities, government and industrial research organisations, whose work involves the use of organophosphorus compounds. It provides a concise but comprehensive survey of a vast field of study with a wide variety of applications, enabling the reader to rapidly keep abreast of the latest developments in their specialist areas. Specialist Periodical Reports provide systematic and detailed review coverage of progress in the major areas of chemical research. Written by experts in their specialist fields the series creates a unique service for the active research chemist, supplying regular critical in-depth accounts of progress in particular areas of chemistry. For over 80 years the Royal Society of Chemistry and its predecessor, the Chemical Society, have been publishing reports charting developments in chemistry, which originally took the form of Annual Reports. However, by 1967 the whole spectrum of chemistry could no longer be contained within one volume and the series Specialist Periodical Reports was born. The Annual Reports themselves still existed but were divided into two, and subsequently three, volumes covering Inorganic, Organic and Physical Chemistry. For more general coverage of the highlights in chemistry they remain a 'must'. Since that time the SPR series has altered according to the fluctuating degree of activity in various fields of chemistry. Some titles have remained unchanged, while others have altered their emphasis along with their titles; some have been combined under a new name whereas others have had to be discontinued. The current list of Specialist Periodical Reports can be seen on the inside flap of this volume.
Author: Chris Timperley
Publisher: Newnes
ISBN: 0080982247
Category : Technology & Engineering
Languages : en
Pages : 787
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Book Description
Best Synthetic Methods: Organophosphorus (V) Chemistry provides systematic coverage of the most common classes of pentavalent organophosphorus compounds and reagents (including phosphonyl, phosphoryl, and organophosphates), and allows researchers an easy point of entry into this complex and economically important field. The book follows the Best Synthetic Methods format, containing practical methods, synthetic tips, and shortcuts. Where relevant, articles include toxicity data and historical context for the reactions. Typical analytical and spectroscopic data are also presented to enable scientists to identify key compound characteristics. The book is a valuable companion to research chemists in both academia and industry, summarizing the best practical methods (often originating in difficult-to-access, foreign-language primary literature) in one place. It is ideally suited for those working on industrial applications of these compounds, including insecticides, herbicides, flame retardants, and plasticizers. - Includes a mixture of tried and tested, historical methods that are proven to work, alongside new methods to provide scientists with a quick, time-saving resource of reliable methods - Includes tips and tricks to get reactions to work; important information often missing from other sources - Includes key analytical data for compounds, so scientists have one handy resource to select, perform, and analyze the best reaction
Author: Robert Engel
Publisher: CRC Press
ISBN: 9780824787332
Category : Science
Languages : en
Pages : 916
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Book Description
This practical work summarizes the development of organophosphorus chemistry in topical areas and details the discipline's current state - providing applications and experimental procedures throughout.;Written by 18 leading authorities in the field, the Handbook of Organophosphorus Chemistry: examines advances in the mechanistic understanding of the Perkow and related organophosphorus reactions; describes methods for the reduction of quinquevalent to trivalent phosphorus and their applications to standard synthetic procedures; emphasizes the preparation of phosphonates bearing hydroxy, amino, and thiol functions at the alpha-position relative to the phosphoryl group; reviews the basics of NMR as it applies to the 31P nucleus, considering the use of the latest measurement techniques in solving structural and mechanistic problems; compares the characteristics of polymer-based and monomeric materials; and presents recent progress in the design of insecticides and covers their chemical and biological characteristics.;Generously referenced with close to 3000 bibliographic citations, the Handbook of Organophosphorus Chemistry is an important volume for organic, medicinal, and agricultural chemists and biochemists; pharmacists; chemical engineers; and graduate-level students in these disciplines.
Author: Dr. Patrick J. Murphy
Publisher: Practical Approach in Chemistr
ISBN: 9780198502623
Category : Science
Languages : en
Pages : 296
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Book Description
Organophosphorus Chemistry: A Practical Approach in Chemistry provides a practical introduction to the field by mixing a brief review of the subject area with key experimental details and sample procedures. Phosphorus is an element that has been central to the development of our modern way of life. Its chemistry plays a key role in the development of such important areas as pharmaceuticals, agrochemicals, modern materials and molecular biology. Much of this work requires a sound understanding of the organic chemistry of phosphorus and this volume is designed to instruct the reader in the essential methodology used. Topics covered include phosphines, applications of phosphorus (III) and (V) compounds as reagents in synthesis, the chemistry of phosphorus ylides, applications of the Wittig reaction in the synthesis of heterocyclic and carbocyclic compounds, preparation of Iminophosphoranes and their synthetic applications in the aza-Wittig reaction, phospho-transfer processes leading to [P-C] bond formation, low valent phosphorus compounds and phosphorus methods in oligonucleotide chemistry. It is intended not only for the specialist in organophosphorus chemistry, but also for the organic chemist with little experience in the field who wishes to add phophorus-based techniques to his or her ensemble of synthetic methods.
Author: Olivier Thomas
Publisher: Elsevier
ISBN: 0080489842
Category : Science
Languages : en
Pages : 373
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Book Description
UV-Visible Spectrophotometry of Water and Wastewater is the first book dedicated to the use of UV spectrophotometry for water and wastewater quality monitoring. Using practical examples the reader is shown how this technique can be a source of new methods of characterization and measurement. Easy and fast to run, this simple and robust analytical technique must be considered as one of the best ways to obtain a quantitative estimation of specific or aggregate parameters (eg. Nitrate, TOC), and simultaneously qualitative information on the global composition of water and its variation.* First electronic library of UV-spectra providing data readily available for researchers and users* Provides a theoretical basis for further research in the field of spectra exploitation* Contains helpful practical applications
Author: Lee J Higham
Publisher: Royal Society of Chemistry
ISBN: 183916381X
Category : Science
Languages : en
Pages : 504
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Book Description
This annual review of the literature, the 50th volume in the present series, provides a comprehensive and critical survey of a vast field of study involving organophosphorus compounds, ranging from phosphines, their chalcogenide derivatives and phosphonium salts, phosphorus (III) acid derivatives, phosphorus (V) acids, penta- and hexa-coordinated phosphorus compounds, phosphazenes and related phosphorus-nitrogen bonded compounds. Coverage is also presented of applications of organophosphorus compounds in homogeneous catalysis for synthesis of bulk and fine chemicals and also in applications as reagents in green synthetic procedures.
