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Author: Raymond Cross, MD, MS
Publisher: Integritas Communications
ISBN: 0998419435
Category : Health & Fitness
Languages : en
Pages : 62
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Book Description
In the past 2 decades, the introduction of biologic therapies that target underlying disease processes has dramatically changed the treatment of the inflammatory bowel diseases (IBDs), ulcerative colitis and Crohn’s disease. Current biologic therapy with tumor necrosis factor inhibitors and anti-integrins has improved the treatment of IBD flares and maintenance of clinical remission. These agents are, however, limited by primary nonresponse and loss of response in a substantial proportion of patients, disease relapse after cessation of therapy, immunogenicity, and adverse effects such as risk for infection and malignancy. As the pathogenesis and treatment of IBD are complex and variable, there is a need to better understand the underlying pathogenic mechanisms and develop drug therapies to target these mechanisms. Geared to the needs of gastroenterologists, this IBD eHealth program includes an update on patient assessment and treat-to-target goals, as well as a review of best practices in shared decision-making in treatment decisions for induction and maintenance of remission. In addition, the immunopathogenesis of IBD is discussed in the context of current and emerging targeted therapies for moderate to severe disease.
Author: Raymond Cross, MD, MS
Publisher: Integritas Communications
ISBN: 0998419435
Category : Health & Fitness
Languages : en
Pages : 62
Get Book Here
Book Description
In the past 2 decades, the introduction of biologic therapies that target underlying disease processes has dramatically changed the treatment of the inflammatory bowel diseases (IBDs), ulcerative colitis and Crohn’s disease. Current biologic therapy with tumor necrosis factor inhibitors and anti-integrins has improved the treatment of IBD flares and maintenance of clinical remission. These agents are, however, limited by primary nonresponse and loss of response in a substantial proportion of patients, disease relapse after cessation of therapy, immunogenicity, and adverse effects such as risk for infection and malignancy. As the pathogenesis and treatment of IBD are complex and variable, there is a need to better understand the underlying pathogenic mechanisms and develop drug therapies to target these mechanisms. Geared to the needs of gastroenterologists, this IBD eHealth program includes an update on patient assessment and treat-to-target goals, as well as a review of best practices in shared decision-making in treatment decisions for induction and maintenance of remission. In addition, the immunopathogenesis of IBD is discussed in the context of current and emerging targeted therapies for moderate to severe disease.
Author: Stephan R. Targan
Publisher: John Wiley & Sons
ISBN: 1444359118
Category : Medical
Languages : en
Pages : 1429
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Book Description
This is the state-of–the-art book on inflammatory bowel disease you have been waiting for Written and edited by international experts in gastroenterology this up-to-date volume provides a complete review of the basic science behind inflammatory bowel disease (IBD), as well as evidence-based clinical guidance on diagnosis, treatment and long-term management of IBD. In 50 chapters the authors cover the latest and most promising treatment modalities and the science behind them. There are chapters which cover the advances in the medical and surgical treatment of conditions such as Crohn's disease and ulcerative colitis, as well as chapters focusing on nutrition, imaging and complementary medicine. This is an invaluable information resource for all those in the medical team treating patients with IBD. Whether you are a gastroenterologist, gastrointestinal surgeon or GI nurse specialist this book deserves a place in your library.
Author: Pär Myrelid
Publisher: Springer
ISBN: 3319955918
Category : Medical
Languages : en
Pages : 201
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Book Description
This book is about the recently revived technique of Kock pouch in inflammatory bowel disease. It discusses the Kock pouch as an alternative to patients not suitable for a pelvic pouch or where the pelvic pouch has failed. It provides clinicians with all the necessary information on patient guidance and surgical revisions after a long life with a Kock pouch. The reader will learn about the development of the pouch, pre and post-operative strategies, surveillance, complications and the limitations and weaknesses of the method. New pioneering experimental methods used by the authors are also discussed. The use of ileorectal anastomosis and Kock’s continent ileostomy has regained interest as the long term problems of the pelvic pouch have and this book brings the knowledge and valuable experiences of a few experts at international centres to a large audience. This is an indispensable guide for colorectal surgeons, gastroenterologists and stoma therapi sts involved in the care of patients with inflammatory bowel disease where colectomy is still needed, either in an emergency setting or due to dysplasia or cancer.
Author: Petar Mamula
Publisher: Springer Science & Business Media
ISBN: 1461450616
Category : Medical
Languages : en
Pages : 573
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Book Description
Pediatric Inflammatory Bowel Disease, Second Edition provides an essential reference with an emphasis on the unique pediatric issues of IBD. Chapters focus on complications of IBD specific to children and adolescents. Treatment recommendations are based on the latest clinical research available. The textbook also presents sections dedicated to the aspects of participation in clinical research unique to children and adolescents and the complicated yet vital process of successfully transitioning a patient from a pediatric to adult specialist. Controversies in pediatric IBD care such as the off-label use of medications are also covered. The format incorporates multiple tables, graphs, and figures to improve readability and make for an efficient reference for clinicians to use. Thoroughly revised and updated from the first edition, the volumes includes new therapies that are currently being used or tested for treatment of IBD, important areas regarding incidence and prevalence, immunization and response to vaccine administration as well as advancements in our understanding of growth and development with particular to the use of growth hormone therapy. Other new areas covered include important topics of complementary and alternative medicine use in IBD, immunization, and liver disease in IBD. Pediatric Inflammatory Bowel Disease, Second Edition is a valuable resource for pediatric gastroenterologists as well as adult gastroenterologists.
Author: Masato Kusunoki
Publisher: Springer
ISBN: 4431555226
Category : Medical
Languages : en
Pages : 151
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Book Description
As the number of patients with colitis-associated cancer (CAC) is on the increase, the purpose of this book is to review the latest topics concerning management of the disease. In recent years, the diagnostic power of endoscopy and molecular pathology has also grown tremendously, as a result of which they now have a far greater influence on the treatment of CAC. At the moment, appropriate monitoring programs for ulcerative colitis and Crohn’s disease remain uncertain. At the same time, the latest findings on DNA methylation and microRNAs hold the promise of making revolutionary changes in these areas. Moreover, recent drug advances in the treatment of inflammatory bowel diseases have changed surgical indications. On the other hand, the indication of mucosectomy on colorectal cancer in ulcerative colitis and prophylactic abdominoperineal resection for Crohn’s disease remain controversial. This book provides the latest information on the remaining issues of CAC from the point of view of expert surgeons.
Author: Matthew Baillie
Publisher:
ISBN:
Category : Anatomy
Languages : en
Pages : 390
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Book Description
Author: Lizhi Zhang
Publisher: Springer
ISBN: 3030155730
Category : Medical
Languages : en
Pages : 564
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Book Description
This book covers the entire spectrum of non-neoplastic diseases within the gastrointestinal (GI) tract including new entities, recent developments, and questions that arise in the practice of GI pathology. The text is organized by specific organ site, with related disorders of each organ site subgrouped into several chapters based on their common features. Pathologists can quickly find the disorders they are interested and review similar disorders in the same chapter to help them make a correct diagnosis. Each major and common entity is described in detail with its definition, clinical features, pathological features (covering both the gross and microscopic details), differential diagnosis and treatment/prognosis. All chapters also highlight the use of special/immunohistochemical stains and other supporting studies as needed with a focus on providing a practical differential diagnosis rather than just a list of potential associations. This book is extensively illustrated with both gross and microscopic images that act as an integral part of the information provided in the text. Written by practicing GI/liver pathologists and gastroenterologists from the Mayo Clinic, Surgical Pathology of Non-neoplastic Gastrointestinal Diseases serves as a comprehensive yet practical guide for diagnostic surgical pathologists with a passion for GI pathology.
Author: Gary W. Miller
Publisher: Elsevier
ISBN: 0124172180
Category : Science
Languages : en
Pages : 118
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Book Description
The Exposome: A Primer is the first book dedicated to exposomics, detailing the purpose and scope of this emerging field of study, its practical applications and how it complements a broad range of disciplines. Genetic causes account for up to a third of all complex diseases. (As genomic approaches improve, this is likely to rise.) Environmental factors also influence human disease but, unlike with genetics, there is no standard or systematic way to measure the influence of environmental exposures. The exposome is an emerging concept that hopes to address this, measuring the effects of life-long environmental exposures on health and how these exposures can influence disease. This systematic introduction considers topics of managing and integrating exposome data (including maps, models, computation, and systems biology), "-omics"-based technologies, and more. Both students and scientists in disciplines including toxicology, environmental health, epidemiology, and public health will benefit from this rigorous yet readable overview.
Author: William A. Oleckno
Publisher: Waveland Press
ISBN: 1478609842
Category : Medical
Languages : en
Pages : 664
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Book Description
Comprehensive in its coverage and suitable for graduate or upper-division undergraduate students in a wide range of health-related disciplines, this latest offering by William A. Oleckno is a full-scale, pedagogically rich introduction to fundamental ideas and procedures in epidemiology. The text covers the major concepts, principles, methods, and applications of both conventional and modern epidemiology using clear language and frequent examples to illustrate important points and facilitate understanding. While Oleckno provides thorough treatment of the more customary aspects of conventional and modern epidemiology, he also introduces several important design and analytical issues that are only rarely approached in fundamental epidemiology textbooks. Concepts as diverse as competing risks, maturation, futility, and the prevalence and bias effects in the context of screening are just a few examples of the broad range of concepts covered in this text. A comprehensive glossary contains detailed definitions of over 700 terms used throughout the 14 chapters comprising the textbook. Aspiring public health professionals will appreciate the solid basis they gain from Epidemiology: Concepts and Methods and will want to keep a copy close by as a valuable reference throughout their careers.
Author: Daniel C. Baumgart
Publisher: Springer
ISBN: 3319337033
Category : Medical
Languages : en
Pages : 671
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Book Description
This new edition is a unique combined resource for physicians and scientists addressing the needs of both groups. In addition to stimulating exchange and collaboration and shortening the path between discovery and application of new knowledge, the book helps clinicians understand new therapeutic concepts from their origins. The volume serves as a comprehensive guide to the current diagnostic modalities, including enhanced imaging techniques such as MRI and CT enterography, virtual colonoscopy, ultrasound, and endomicroscopy, as well as conventional and complex immunomodulatory principles. The latest edition also includes revised chapters from the previous edition, as well as new chapters reflecting current developments in the field. Written by experts in their field, Crohn’s Disease and Ulcerative Colitis: From Epidemiology and Immunobiology to a Rational Diagnostic and Therapeutic Approach, Second Edition is of great value to gastroenterologists, surgeons, internists, pediatricians and gynecologists trainees, as well as all those involved in Crohn’s disease, ulcerative colitis, and related autoimmune disorders.
