The Baboon in Biomedical Research

The Baboon in Biomedical Research PDF Author: John L. VandeBerg
Publisher: Springer Science & Business Media
ISBN: 0387759913
Category : Science
Languages : en
Pages : 405

Get Book Here

Book Description
Nonhuman primates have played critical roles in biomedical research, and they are among the few animals whose use in research continues to increase. The scienti?c value of nonhuman primates derives from their close phylogenetic proximity to man and their consequent anatomic, physiologic, and genetic similarities to man. Only nonhuman primates can provide adequate models for many complex physiological and disease processes of humans. The baboon is a relative newcomer to the repertoire of nonhuman primates used in biomedical research. However, in less than 50 years since its ?rst use in the U. S. , it has become one of the most popular laboratory primate species. It is larger than the other widely used monkey species, making it advantageous for many types of experiments and technological developments. It is extraordinarily hardy and highly fecund in captivity. It closely resembles humans in a variety of physiological and disease processes, such as cholesterol metabolism, early stages of atherosclerosis, and alcoholic liver disease. Its chromosomes closely resemble those of humans, and many genes of the two species lie in the same chromosomal order. Among all primates, baboons are the most widely used models for the genetics of susceptibility to complex diseases and they are the ?rst nonhuman primate for which a framework genetic linkage map was established. In addition, the baboon genome is currently being sequenced, and as a result the utility of this species for biomedical research will be dramatically increased.

Enrichment for Nonhuman Primates

Enrichment for Nonhuman Primates PDF Author:
Publisher:
ISBN:
Category : Primates
Languages : en
Pages : 16

Get Book Here

Book Description


Ethics Dumping

Ethics Dumping PDF Author: Doris Schroeder
Publisher: Springer
ISBN: 3319647318
Category : Philosophy
Languages : en
Pages : 144

Get Book Here

Book Description
This open access book provides original, up-to-date case studies of “ethics dumping” that were largely facilitated by loopholes in the ethics governance of low and middle-income countries. It is instructive even to experienced researchers since it provides a voice to vulnerable populations from the fore mentioned countries. Ensuring the ethical conduct of North-South collaborations in research is a process fraught with difficulties. The background conditions under which such collaborations take place include extreme differentials in available income and power, as well as a past history of colonialism, while differences in culture can add a new layer of complications. In this context, up-to-date case studies of unethical conduct are essential for research ethics training.

Animal Experimentation

Animal Experimentation PDF Author: Kathrin Herrmann
Publisher:
ISBN: 9789004356184
Category : Animal experimentation
Languages : en
Pages : 0

Get Book Here

Book Description
Animal Experimentation: Working Towards a Paradigm Change critically appraises current animal use in science and discusses ways in which we can contribute to a paradigm change towards human-biology based approaches.

Long-Term Field Studies of Primates

Long-Term Field Studies of Primates PDF Author: Peter M. Kappeler
Publisher: Springer Science & Business Media
ISBN: 3642225136
Category : Science
Languages : en
Pages : 473

Get Book Here

Book Description
Some primate field studies have been on-going for decades, covering significant portions of individual life cycles or even multiple generations. In this volume, leading field workers report on the history and infrastructure of their projects in Madagascar, Africa, Asia and South America. More importantly, they provide summaries of their long-term research efforts on primate behaviour, ecology and life history, highlighting insights that were only possible because of the long-term nature of the study. The chapters of this volume collectively outline the many scientific reasons for studying primate behaviour, ecology and demography over multiple generations. This kind of research is typically necessitated by the relatively slow life histories of primates. Moreover, a complete understanding of social organization and behaviour, factors often influenced by rare but important events, requires long-term data collection. Finally, long-term field projects are also becoming increasingly important foci of local conservation activities.

Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research

Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 030916785X
Category : Science
Languages : en
Pages : 223

Get Book Here

Book Description
Expanding on the National Research Council's Guide for the Care and Use of Laboratory Animals, this book deals specifically with mammals in neuroscience and behavioral research laboratories. It offers flexible guidelines for the care of these animals, and guidance on adapting these guidelines to various situations without hindering the research process. Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research offers a more in-depth treatment of concerns specific to these disciplines than any previous guide on animal care and use. It treats on such important subjects as: The important role that the researcher and veterinarian play in developing animal protocols. Methods for assessing and ensuring an animal's well-being. General animal-care elements as they apply to neuroscience and behavioral research, and common animal welfare challenges this research can pose. The use of professional judgment and careful interpretation of regulations and guidelines to develop performance standards ensuring animal well-being and high-quality research. Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research treats the development and evaluation of animal-use protocols as a decision-making process, not just a decision. To this end, it presents the most current, in-depth information about the best practices for animal care and use, as they pertain to the intricacies of neuroscience and behavioral research.

Veterinary Cytology

Veterinary Cytology PDF Author: Leslie C. Sharkey
Publisher: John Wiley & Sons
ISBN: 1119125723
Category : Medical
Languages : en
Pages : 1027

Get Book Here

Book Description
This book offers a state-of-the-art, evidence-based reference to all aspects of veterinary cytology. Truly multidisciplinary in its approach, chapters are written by experts in fields ranging from clinical pathology to internal medicine, surgery, ophthalmology, and dermatology, drawing the various specialties together to create a comprehensive picture of cytology's role in diagnosis and treatment of animal disease. Firmly grounded in the primary literature, the book focuses on companion animals, with special chapters for species with fewer publications. Chapters are logically organized by body system, with additional chapters on tumors of particular import and diagnostic decision making. The first two sections of Veterinary Cytology focus on cytology techniques, quality control, and special laboratory techniques. Subsequent sections are organ/tissue-based and reflect what is known about the canine, feline, and equine species. This is followed by chapters on non-traditional species, including exotic companion mammals, rabbits, cattle, camelids, non-human primates, reptiles and birds, amphibians, fish, invertebrates, and sheep and goats. The last section highlights some unique features of the applications of cytology in industry settings. Provides a gold-standard reference to data-driven information about cytologic analysis in companion animal species Brings together authors from a wide range of specialties to present a thorough survey of cytology's use in veterinary medicine Offers broader species coverage and greater depth than any cytology reference currently available Veterinary Cytology is an essential resource for clinical and anatomic pathologists and any specialist in areas using cytology, including veterinary oncologists, criticalists, surgeons, ophthalmologists, dermatologists, and internists.

Occupational Health and Safety in the Care and Use of Nonhuman Primates

Occupational Health and Safety in the Care and Use of Nonhuman Primates PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 0309167949
Category : Science
Languages : en
Pages : 180

Get Book Here

Book Description
The field of occupational health and safety constantly changes, especially as it pertains to biomedical research. New infectious hazards are of particular importance at nonhuman-primate facilities. For example, the discovery that B virus can be transmitted via a splash on a mucous membrane raises new concerns that must be addressed, as does the discovery of the Reston strain of Ebola virus in import quarantine facilities in the U.S. The risk of such infectious hazards is best managed through a flexible and comprehensive Occupational Health and Safety Program (OHSP) that can identify and mitigate potential hazards. Occupational Health and Safety in the Care and Use of Nonhuman Primates is intended as a reference for vivarium managers, veterinarians, researchers, safety professionals, and others who are involved in developing or implementing an OHSP that deals with nonhuman primates. The book lists the important features of an OHSP and provides the tools necessary for informed decision-making in developing an optimal program that meets all particular institutional needs.

Environmental Enrichment and Refinement for Nonhuman Primates Kept in Research Laboratories

Environmental Enrichment and Refinement for Nonhuman Primates Kept in Research Laboratories PDF Author: Viktor Reinhardt
Publisher:
ISBN:
Category : Animal welfare
Languages : en
Pages : 148

Get Book Here

Book Description


The Pictorial Guide to the Living Primates

The Pictorial Guide to the Living Primates PDF Author: Noel Rowe
Publisher:
ISBN:
Category : Nature
Languages : en
Pages : 284

Get Book Here

Book Description
This beautiful book illustrates the diversity of the primate order. Each species is treated separately. This book includes the 10 new species which have been described in the last fifteen years. Over 100 primates are presently threatened or endanger of extinction. Anyone interested in primates will love this book.