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Author: Paulo V. Brantus
Publisher: Nova Publishers
ISBN: 9781600216671
Category : Medical
Languages : en
Pages : 166
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Book Description
Seminomas account for about 30-40% of all testicular tumours. These are usually is found in men in their 30s and 40s. The condition is usually localised to the testes, although in about 25% of cases it has spread to lymph nodes. Non-seminomas account for 60% of all testicular tumours; subcategories of these tumours are listed below. Non-seminoma tumours often contain more than one of the following cell types: Testicular cancer is an abnormal, rapid, and invasive growth of cancerous (malignant) cells in the testicles. Embryonal carcinoma (about 20% of testicular cancers) occurs in 20-30 year olds and is highly malignant. It grows rapidly and spreads to the lung and liver. Yolk sac tumour (about 60% of all testicular cancers in young boys). Teratomata (about 7% of testicular cancers in adult men and 40% in young boys). Choriocarcinoma is rare. Stromal cell tumours are a kind of tumour that is made of Leydig cells (testosterone-secreting cells), Sertoli cells (cells where sperm matures), and granulose cells. These tumours account for only 3-4% of all testicular tumours. However, they do make up nearly 20% of all childhood testicular tumours. These tumours may secrete a hormone -- estradiol -- that can cause one of the symptoms of testicular cancer, gynecomastia (excessive development of breast tissue). This book presents leading-edge research in the field.
Author: Paulo V. Brantus
Publisher: Nova Publishers
ISBN: 9781600216671
Category : Medical
Languages : en
Pages : 166
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Book Description
Seminomas account for about 30-40% of all testicular tumours. These are usually is found in men in their 30s and 40s. The condition is usually localised to the testes, although in about 25% of cases it has spread to lymph nodes. Non-seminomas account for 60% of all testicular tumours; subcategories of these tumours are listed below. Non-seminoma tumours often contain more than one of the following cell types: Testicular cancer is an abnormal, rapid, and invasive growth of cancerous (malignant) cells in the testicles. Embryonal carcinoma (about 20% of testicular cancers) occurs in 20-30 year olds and is highly malignant. It grows rapidly and spreads to the lung and liver. Yolk sac tumour (about 60% of all testicular cancers in young boys). Teratomata (about 7% of testicular cancers in adult men and 40% in young boys). Choriocarcinoma is rare. Stromal cell tumours are a kind of tumour that is made of Leydig cells (testosterone-secreting cells), Sertoli cells (cells where sperm matures), and granulose cells. These tumours account for only 3-4% of all testicular tumours. However, they do make up nearly 20% of all childhood testicular tumours. These tumours may secrete a hormone -- estradiol -- that can cause one of the symptoms of testicular cancer, gynecomastia (excessive development of breast tissue). This book presents leading-edge research in the field.
Author: Heather Hasan
Publisher: The Rosen Publishing Group, Inc
ISBN: 1448813123
Category : Juvenile Nonfiction
Languages : en
Pages : 66
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Book Description
Describes testicular cancer, including diagnosis and treatment, who is at risk for the disease, and the future of scientific research on the cancer.
Author: Manuel Regouc
Publisher:
ISBN: 9781022898738
Category : Medical
Languages : en
Pages : 0
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Book Description
Turning the Tide: Insights in Testicular Cancer Research and Awareness is a curated collection of pioneering scientific journal articles that delve into the complex world of testicular cancer. This compendium presents a multifaceted exploration of the latest research findings and clinical observations pertaining to testicular cancer, a disease that significantly impacts men worldwide. The book covers a broad spectrum of topics, including the role of non-coding microRNAs as emerging tumor markers, seasonal variations in diagnosis, and the implications of subfertility as a risk factor. In addition, it addresses the critical issue of public awareness and the importance of testicular self-examination, with specific studies focusing on populations in Malta, Nepal, and Poland. The compilation also includes compelling clinical case studies, such as testicular sarcoidosis and metastasis from small bowel cancer, highlighting the need for precise diagnostic approaches. Furthermore, the book discusses genetic, environmental, and hormonal influences on testicular cancer development, emphasizing the need for a holistic understanding and integrated preventive measures. This volume is essential reading for medical professionals, researchers, students, and anyone invested in advancing men's health and cancer research. Dive into these pages to gain comprehensive insights and contribute to the ongoing quest for better diagnosis, treatment, and awareness of testicular cancer. Quality Research Publishing is dedicated to making knowledge more accessible to the general public by curating a topical compilation of the latest research on various subjects and providing plain language summaries. Each of the articles in this book is available individually and digitally without cost. However, we believe it is important for the contextualizing and sharing of educational and scientific work to curate this research in a way that is understandable and helpful to the average person seeking deeper knowledge of a particular subject. The research articles compiled for this book were published under a permissive Creative Commons license, are in the public domain, or have no copyright restrictions, permitting their use in this book. If you have questions about the licensing of any article, please visit qualityresearchpublishing.com.
Author: Susanne Krege
Publisher: Springer
ISBN: 3319174673
Category : Medical
Languages : en
Pages : 136
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Book Description
This book presents the views of leading European experts on the diagnosis and management of testicular cancer, with coverage of current hot topics in the field. It opens by providing an overview of the recommendations in the most recent consensus paper from the European Germ Cell Cancer Consensus Group, which is based on interdisciplinary cooperation among urologists, medical oncologists, radio-oncologists, pathologists, and basic scientists. The remainder of the book focuses on areas of controversy in the diagnosis, treatment, and follow-up of testicular cancer. In each case the evidence base is discussed and results from the most recent studies are reviewed, drawing attention to new findings that might alter treatment recommendations. The treatment-related chapters cover a broad range of issues, including the best approach in patients with poor-prognosis and recurrent disease and those with long-term toxicities. Relevant aspects of survivorship care are also addressed. The book will help clinicians and practitioners to achieve the goals of minimizing therapy and its side-effects without reducing efficacy in low stage disease, improving the cure rate in advanced disease, and enhancing follow-up and long-term survivorship.
Author: Cancer Research UK.
Publisher:
ISBN:
Category : Testis
Languages : en
Pages : 6
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Book Description
Author:
Publisher: ScholarlyEditions
ISBN: 1464979278
Category : Medical
Languages : en
Pages : 31
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Book Description
Testicular Cancer: New Insights for the Healthcare Professional / 2012 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Testicular Cancer in a compact format. The editors have built Testicular Cancer: New Insights for the Healthcare Professional / 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Testicular Cancer in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Testicular Cancer: New Insights for the Healthcare Professional / 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Author: Thomas Michaeli
Publisher:
ISBN: 9781022897922
Category : Medical
Languages : en
Pages : 0
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Book Description
In 'Journeys into Testicular Cancer: Research, Treatments, and Survivorship', the latest scientific advancements and personal experiences unite to provide a comprehensive overview of testicular cancer. This anthology of journal articles explores various facets of testicular cancer, from cutting-edge treatment strategies like targeting cancer stem cells with differentiation agents to the economic implications of follow-up costs in Germany. Readers will discover the nuanced impacts of chemotherapy on fertility in prepubertal boys and the genetic and biomarker approaches that herald the era of personalized medicine. Treatments are seen not only through their clinical efficacy but also in their psychosocial effects, such as cognitive impairments in long-term survivors and emotional adjustments with testicular prostheses. Additionally, articles delve into the complexities of diagnosing and managing rare occurrences like metachronous testicular cancer and the diagnostic value of neutrophil-to-lymphocyte ratios. Aimed at clinicians, researchers, and policymakers, this collection does more than recount progress; it weaves a narrative of persistent human resilience and scientific curiosity in the fight against testicular cancer. Quality Research Publishing is dedicated to making knowledge more accessible to the general public by curating a topical compilation of the latest research on various subjects and providing plain language summaries. Each of the articles in this book is available individually and digitally without cost. However, we believe it is important for the contextualizing and sharing of educational and scientific work to curate this research in a way that is understandable and helpful to the average person seeking deeper knowledge of a particular subject. The research articles compiled for this book were published under a permissive Creative Commons license, are in the public domain, or have no copyright restrictions, permitting their use in this book. If you have questions about the licensing of any article, please visit qualityresearchpublishing.com.
Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 0
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Book Description
Testicular cancer (TC) is the most common cancer in males aged 20-40 years, with a worldwide incidence of 7.5 per 100,000, but the rates vary considerably between countries and ethnic groups and there is evidence also for an increasing incidence in last decades. About 95% of all TCs are represented by testicular germ cell tumors (TGCTs), which include seminoma and non-seminoma histological types. It is generally assumed that the development of TGCT is under endocrine control. In particular, unbalanced androgen/estrogen levels and/or activity are believed to represent the key events for TGCT development and progression. Furthermore, recent evidence has suggested genetic association of TGCT with variations in genes involved in hypothalamic-pituitary-testicular axis and steroidogenic enzymes. This recent evidence expands the current knowledge on the role of genetic contribution in testicular cancer susceptibility, and supports the hypothesis that variations in hormone metabolism genes might change the hormonal environment implicated in testicular carcinogenesis. Therefore, hormonal carcinogenesis is an important and controversial area of current research in TGCT, and further attention is given to genetic factors influencing hormone-related cancer risk. The genetic component to TGCT is in general strong. In fact, although environmental factors clearly contribute to TGCT development (and probably to its increasing incidence in some geographical areas), the proportion of TGCT susceptibility accounted for by the genetic effects is estimated at 25%. TGCT has high familial risks compared with most other cancer types that are generally no more than two-fold: brothers of individuals with TGCT have an 8- to 12-fold increased risk of disease, and sons of affected individuals have a 4- to 6-fold increased risk. Despite this strong familial relative risk, early results from linkage studies identified a limited relationship with genetic factors, suggesting that TGCT is a genetically complex trait. However, more recently, four genome-wide association studies (GWAS) from the UK and USA have reported association of TGCTs with six new loci (KITLG, SPRY4, BAK1, DMRT1, TERT, and ATF7IP). The strongest association for TGCT susceptibility was found for SNPs in KITLG (ligand for the membrane-bound receptor tyrosine kinase KIT) gene with a greater than 2.5-fold increased risk of disease per major allele, which is the highest reported for any cancer to date. These studies are being now replicated by other researches and attention is given to the relationship between these genetic variations, TGCT risk and frequently associated anomalies of the reproductive tract, such as cryptorchidism and infertility. Finally, over the past few decades, TCGT research has focused also on external environmental causes acting mainly as endocrine disrupters of androgen and oestrogen pathways, even during the foetal development of the testis. It is well known that the testicular dysgenesis syndrome (TDS) hypothesis, proposed ten years ago, suggests that disturbed testicular development in fetal life may result in one or more of four disorders postnatally, named cryptorchidism, hypospadias, poor semen quality, and TGCT. These four disorders are therefore considered as one clinical entity and are linked together by epidemiological and pathophysiological relations. The relative contribution of genetics and environment in TGCT development, and the interactions between endocrine disruptors and variations in genes involved in hormonal carcinogenesis is therefore another interesting area of research.
Author: Luciano Giuliani
Publisher:
ISBN: 9783927759039
Category :
Languages : en
Pages : 302
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Book Description
Author: Mahul B. Amin
Publisher: Lippincott Williams & Wilkins
ISBN: 1469857960
Category : Medical
Languages : en
Pages : 2443
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Book Description
Knowledge in the field of urologic pathology is growing at an explosive pace. Today’s pathologists, specialists, and residents require a comprehensive and authoritative text that examines the full range of urological diseases and their diagnosis. Written by recognized leaders and educators in the field, the text provides readers with a detailed understanding of all diagnostic aspects of urological disease. Inside this unique resource, readers will explore a broad spectrum of practical information—including etiology, diagnostic criteria, molecular markers, differential diagnosis, ancillary tests, and clinical management. This is sure to be the new definitive text for urological pathology!
