System Engineering Approach to Planning Anticancer Therapies PDF Download
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Author: Andrzej Świerniak
Publisher: Springer
ISBN: 3319280953
Category : Mathematics
Languages : en
Pages : 241
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Book Description
This book focuses on the analysis of cancer dynamics and the mathematically based synthesis of anticancer therapy. It summarizes the current state-of-the-art in this field and clarifies common misconceptions about mathematical modeling in cancer. Additionally, it encourages closer cooperation between engineers, physicians and mathematicians by showing the clear benefits of this without stating unrealistic goals. Development of therapy protocols is realized from an engineering point of view, such as the search for a solution to a specific control-optimization problem. Since in the case of cancer patients, consecutive measurements providing information about the current state of the disease are not available, the control laws are derived for an open loop structure. Different forms of therapy are incorporated into the models, from chemotherapy and antiangiogenic therapy to immunotherapy and gene therapy, but the class of models introduced is broad enough to incorporate other forms of therapy as well. The book begins with an analysis of cell cycle control, moving on to control effects on cell population and structured models and finally the signaling pathways involved in carcinogenesis and their influence on therapy outcome. It also discusses the incorporation of intracellular processes using signaling pathway models, since the successful treatment of cancer based on analysis of intracellular processes, might soon be a reality. It brings together various aspects of modeling anticancer therapies, which until now have been distributed over a wide range of literature. Written for researchers and graduate students interested in the use of mathematical and engineering tools in biomedicine with special emphasis on applications in cancer diagnosis and treatment, this self-contained book can be easily understood with only a minimal basic knowledge of control and system engineering methods as well as the biology of cancer. Its interdisciplinary character and the authors’ extensive experience in cooperating with clinicians and biologists make it interesting reading for researchers from control and system engineering looking for applications of their knowledge. Systems and molecular biologists as well as clinicians will also find new inspiration for their research.
Author: Andrzej Świerniak
Publisher: Springer
ISBN: 3319280953
Category : Mathematics
Languages : en
Pages : 241
Get Book Here
Book Description
This book focuses on the analysis of cancer dynamics and the mathematically based synthesis of anticancer therapy. It summarizes the current state-of-the-art in this field and clarifies common misconceptions about mathematical modeling in cancer. Additionally, it encourages closer cooperation between engineers, physicians and mathematicians by showing the clear benefits of this without stating unrealistic goals. Development of therapy protocols is realized from an engineering point of view, such as the search for a solution to a specific control-optimization problem. Since in the case of cancer patients, consecutive measurements providing information about the current state of the disease are not available, the control laws are derived for an open loop structure. Different forms of therapy are incorporated into the models, from chemotherapy and antiangiogenic therapy to immunotherapy and gene therapy, but the class of models introduced is broad enough to incorporate other forms of therapy as well. The book begins with an analysis of cell cycle control, moving on to control effects on cell population and structured models and finally the signaling pathways involved in carcinogenesis and their influence on therapy outcome. It also discusses the incorporation of intracellular processes using signaling pathway models, since the successful treatment of cancer based on analysis of intracellular processes, might soon be a reality. It brings together various aspects of modeling anticancer therapies, which until now have been distributed over a wide range of literature. Written for researchers and graduate students interested in the use of mathematical and engineering tools in biomedicine with special emphasis on applications in cancer diagnosis and treatment, this self-contained book can be easily understood with only a minimal basic knowledge of control and system engineering methods as well as the biology of cancer. Its interdisciplinary character and the authors’ extensive experience in cooperating with clinicians and biologists make it interesting reading for researchers from control and system engineering looking for applications of their knowledge. Systems and molecular biologists as well as clinicians will also find new inspiration for their research.
Author: Ignacio Rojas
Publisher: Springer
ISBN: 3030179389
Category : Computers
Languages : en
Pages : 544
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Book Description
The two-volume set LNBI 11465 and LNBI 11466 constitutes the proceedings of the 7th International Work-Conference on Bioinformatics and Biomedical Engineering, IWBBIO 2019, held in Granada, Spain, in May 2019. The total of 97 papers presented in the proceedings, was carefully reviewed and selected from 301 submissions. The papers are organized in topical sections as follows: Part I: High-throughput genomics: bioinformatics tools and medical applications; omics data acquisition, processing, and analysis; bioinformatics approaches for analyzing cancer sequencing data; next generation sequencing and sequence analysis; structural bioinformatics and function; telemedicine for smart homes and remote monitoring; clustering and analysis of biological sequences with optimization algorithms; and computational approaches for drug repurposing and personalized medicine. Part II: Bioinformatics for healthcare and diseases; computational genomics/proteomics; computational systems for modelling biological processes; biomedical engineering; biomedical image analysis; and biomedicine and e-health.
Author: Paweł Strumiłło
Publisher: Springer Nature
ISBN: 303138430X
Category : Technology & Engineering
Languages : en
Pages : 457
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Book Description
The book contains 35 chapters, in which you can find various examples of the development of methods and/or systems supporting medical diagnostics and therapy, related to biomedical imaging, signal and image processing, biomaterials and artificial organs, modelling of biomedical systems, which were presented as current research topics at the 23rd Polish Biocybernetics and Biomedical Engineering Conference, held at the Institute of Electronics, Lodz University of Technology in September 2023. The ongoing and dynamic development of AI-based data processing and analysis methods plays an increasingly important role in medicine. This book addresses these issues by presenting applications of such methods in various areas, such as disease diagnosis and prediction, particularly through the use of image data analysis algorithms. Other topics covered include personalized medicine, where multimodal patient data is acquired and analyzed, as well as robotic surgery and clinical decision support. The book is of interest to an advanced and broad readership, including researchers and engineers representing both medical, biological, and engineering viewpoints. Its readers may also be graduate and postgraduate students in various fields such as biomedical engineering, artificial intelligence, biomaterials, and medical electronics, as well as software developers in R&D departments working in the field of intelligent healthcare engineering.
Author: Józef Korbicz
Publisher: Springer Nature
ISBN: 303029885X
Category : Technology & Engineering
Languages : en
Pages : 344
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Book Description
This book gathers 30 papers presented at the 21st PCBBE, which was hosted by the University of Zielona Góra, Poland, and offered a valuable forum for exchanging ideas and presenting the latest developments in all areas of biomedical engineering. Biocybernetics and biomedical engineering are currently considered one of the most promising ways to improve health care and, consequently, the quality of life. Innovative technical solutions can better meet physicians’ needs and stimulate the development of medical diagnostics and therapy. We are currently witnessing a profound change in the role of medicine, which is becoming ubiquitous in everyday life thanks to technological advances. Further, the development of civilization manifests itself in efforts to unlock the secrets of the human body, and to mimic biological systems in engineering. The biannual Polish Conference on Biocybernetics and Biomedical Engineering (PCBBE) has been held for nearly four decades and has attracted scientists and professionals in the fields of engineering, medicine, physics, and computer science. Gathering the outcomes of this conference, the book introduces the reader to recent developments and achievements in biocybernetics and biomedical engineering.
Author: Dorota G. Pijanowska
Publisher: Springer Nature
ISBN: 3030837041
Category : Technology & Engineering
Languages : en
Pages : 142
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Book Description
This book contains 13 chapters in which you can find various examples of the development of methods and/or systems supporting medical diagnostics and therapy, related to biomedical imaging, signal and image processing, biomechanics, biomaterials and artificial organs, modeling of biomedical systems, which, as the current research issues, were presented at the 22nd Polish BBE Conference held at the Nalecz Institute of Biocybernetics and Biomedical Engineering, Polish Academy of Sciences, in May 2021. Obviously, it is not easy to recommend an interdisciplinary book as it may seem inconsistent in some respects. This is the case here because it concerns the area of biocybernetics and biomedical engineering (BBE), which is not only an interdisciplinary but even multidisciplinary science. On the other hand, the scattered subject matter of the book is its advantage, as the book may be of interest to an advanced and wide range of readers and researchers representing both medical, biological and technical points of view.
Author: Roman Szewczyk
Publisher: Springer
ISBN: 3030132730
Category : Technology & Engineering
Languages : en
Pages : 738
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Book Description
This book consists of papers presented at AUTOMATION2019, an international conference held in Warsaw from March 27 to 29, 2019. It discusses the radical technological changes occurring due to the INDUSTRY 4.0. To follow these changes, both scientists and engineers have to face the challenge of interdisciplinary approach directed at the development of cyber-physical systems. This approach encompasses interdisciplinary theoretical knowledge, numerical modelling and simulation as well as application of artificial intelligence techniques. Both software and physical devices are composed into systems that will increase production efficiency and resource savings. The theoretical results, practical solutions and guidelines presented are valuable for both researchers working in the area of engineering sciences and practitioners looking for solutions to industrial problems.
Author: Ngoc Thanh Nguyen
Publisher: Springer Nature
ISBN: 3030419649
Category : Computers
Languages : en
Pages : 684
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Book Description
The two-volume set LNAI 12033 and 11034 constitutes the refereed proceedings of the 12th Asian Conference on Intelligent Information and Database Systems, ACIIDS 2020, held in Phuket, Thailand, in March 2020. The total of 105 full papers accepted for publication in these proceedings were carefully reviewed and selected from 285 submissions. The papers of the first volume are organized in the following topical sections: Knowledge Engineering and Semantic Web, Natural Language Processing, Decision Support and Control Systems, Computer Vision Techniques, Machine Learning and Data Mining, Deep Learning Models, Advanced Data Mining Techniques and Applications, Multiple Model Approach to Machine Learning. The papers of the second volume are divided into these topical sections: Application of Intelligent Methods to Constrained Problems, Automated Reasoning with Applications in Intelligent Systems, Current Trends in Arti cial Intelligence, Optimization, Learning,and Decision-Making in Bioinformatics and Bioengineering, Computer Vision and Intelligent Systems, Data Modelling and Processing for Industry 4.0, Intelligent Applications of Internet of Things and Data AnalysisTechnologies, Intelligent and Contextual Systems, Intelligent Systems and Algorithms in Information Sciences, Intelligent Supply Chains and e-Commerce, Privacy, Security and Trust in Arti cial Intelligence, Interactive Analysis of Image, Video and Motion Data in LifeSciences.
Author: Sebastian Aniţa
Publisher: Springer Nature
ISBN: 3031499719
Category :
Languages : en
Pages : 284
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Book Description
Author: Andrzej Bartoszewicz
Publisher: Springer Nature
ISBN: 3030509362
Category : Technology & Engineering
Languages : en
Pages : 1560
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Book Description
This book presents the proceedings of the 20th Polish Control Conference. A triennial event that was first held in 1958, the conference successfully combines its long tradition with a modern approach to shed light on problems in control engineering, automation, robotics and a wide range of applications in these disciplines. The book presents new theoretical results concerning the steering of dynamical systems, as well as industrial case studies and worked solutions to real-world problems in contemporary engineering. It particularly focuses on the modelling, identification, analysis and design of automation systems; however, it also addresses the evaluation of their performance, efficiency and reliability. Other topics include fault-tolerant control in robotics, automated manufacturing, mechatronics and industrial systems. Moreover, it discusses data processing and transfer issues, covering a variety of methodologies, including model predictive, robust and adaptive techniques, as well as algebraic and geometric methods, and fractional order calculus approaches. The book also examines essential application areas, such as transportation and autonomous intelligent vehicle systems, robotic arms, mobile manipulators, cyber-physical systems, electric drives and both surface and underwater marine vessels. Lastly, it explores biological and medical applications of the control-theory-inspired methods.
Author: Piotr Kulczycki
Publisher: Springer Nature
ISBN: 3030485870
Category : Technology & Engineering
Languages : en
Pages : 843
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Book Description
This book presents a wide and comprehensive range of issues and problems in various fields of science and engineering, from both theoretical and applied perspectives. The desire to develop more effective and efficient tools and techniques for dealing with complex processes and systems has been a natural inspiration for the emergence of numerous fields of science and technology, in particular control and automation and, more recently, robotics. The contributions gathered here concern the development of methods and algorithms to determine best practices regarding broadly perceived decisions or controls. From an engineering standpoint, many of them focus on how to automate a specific process or complex system. From a tools-based perspective, several contributions address the development of analytic and algorithmic methods and techniques, devices and systems that make it possible to develop and subsequently implement the automation and robotization of crucial areas of human activity. All topics discussed are illustrated with sample applications.
