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Author: The International Institute for Strategic Studies (IISS)
Publisher: Taylor & Francis
ISBN: 1000947882
Category : History
Languages : en
Pages : 146
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Book Description
Survival, the IISS’s bimonthly journal, challenges conventional wisdom and brings fresh, often controversial, perspectives on strategic issues of the moment. In this issue: · The Ukraine crisis: Robert Hunter argues that the most important requirement of successful US-led negotiations with Russia is that Moscow demonstrate that it is prepared to be a responsible international actor · Erin Sikorsky contends that climate change should have a larger role in the day-to-day national-security agendas of the United States and other countries · Stephan Frühling and Andrew O’Neil warn that current US debates about no first use tend to underplay the broader alliance implications of any shift in US nuclear policy · Rahul Roy-Chaudhury and Kate Sullivan de Estrada assess that, given the 2021 US FONOP targeting India, Washington and New Delhi need to better manage their diverse positions on global governance, especially in the maritime domain · Nien-chung Chang-Liao warns that pragmatism in Chinese foreign policy is waning and considers why Chinese diplomats have become so aggressive And nine more thought-provoking pieces, as well as our regular Book Reviews and Noteworthy column. Editor: Dr Dana Allin Managing Editor: Jonathan Stevenson Associate Editor: Carolyn West Assistant Editor: Jessica Watson
Author: The International Institute for Strategic Studies (IISS)
Publisher: Taylor & Francis
ISBN: 1000947882
Category : History
Languages : en
Pages : 146
Get Book Here
Book Description
Survival, the IISS’s bimonthly journal, challenges conventional wisdom and brings fresh, often controversial, perspectives on strategic issues of the moment. In this issue: · The Ukraine crisis: Robert Hunter argues that the most important requirement of successful US-led negotiations with Russia is that Moscow demonstrate that it is prepared to be a responsible international actor · Erin Sikorsky contends that climate change should have a larger role in the day-to-day national-security agendas of the United States and other countries · Stephan Frühling and Andrew O’Neil warn that current US debates about no first use tend to underplay the broader alliance implications of any shift in US nuclear policy · Rahul Roy-Chaudhury and Kate Sullivan de Estrada assess that, given the 2021 US FONOP targeting India, Washington and New Delhi need to better manage their diverse positions on global governance, especially in the maritime domain · Nien-chung Chang-Liao warns that pragmatism in Chinese foreign policy is waning and considers why Chinese diplomats have become so aggressive And nine more thought-provoking pieces, as well as our regular Book Reviews and Noteworthy column. Editor: Dr Dana Allin Managing Editor: Jonathan Stevenson Associate Editor: Carolyn West Assistant Editor: Jessica Watson
Author: Lisha Mou
Publisher: Frontiers Media SA
ISBN: 2832550657
Category : Medical
Languages : en
Pages : 126
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Book Description
Owing to the availability of more advanced genetically engineered pigs, more immunological and physiological barriers have been overcome. With the results of pig organ xenotransplantation steadily improving, consideration is now given to the first clinical trials of xenotransplantation. The first step is kidneys, but possibilities also exist in pig islet transplantation for patients with diabetes.
Author: Robb Hollis
Publisher: Frontiers Media SA
ISBN: 283255573X
Category : Medical
Languages : en
Pages : 170
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Book Description
Ovarian cancer is an umbrella term for a collection of distinct disease entities (histotypes). Until now, the majority of research has focussed on the most common histotype, high-grade serous ovarian carcinoma (HGSOC), which accounts for 70% of cases. The less common histotypes – including endometrioid, clear cell, mucinous, low-grade serous, carcinosarcoma, and non-epithelial histotypes – have received far less research attention. Accordingly, while major advances in our understanding of HGSOC have led to molecularly-directed therapies that improve patient outcomes, progress in less common histotypes has lagged behind. Notably, many of the uncommon histotypes demonstrate resistance to conventional chemotherapy regimens, and their inherent biological differences suggest most are unlikely to respond to emerging molecular therapeutics designed to target the biology of common ovarian cancer types.
Author: Praveen Papareddy
Publisher: Frontiers Media SA
ISBN: 2832554555
Category : Medical
Languages : en
Pages : 306
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Book Description
Hospital-acquired infections are common and often result in life-threatening complications, mostly facing critically ill patients in the intensive care unit. Patients with hospital-acquired infections may die from bacteremia/fungal/viral infection or hyperinflammatory complications because of an uncontrolled over-activation of the innate immune system with pathological levels of circulating proinflammatory cytokines, or from multiorgan failure. In addition to eliciting a robust inflammatory response, it paradoxically renders the host in an immunocompromised state at the late stage of the disease progression. Severe infectious diseases, including sepsis and septic shock are among the most common reasons for death in hospitals. Sepsis is an infection-induced syndrome characterized by a generalized inflammatory state and represents a frequent complication in surgical patients and in immunocompromised patients. Sepsis is a common, expensive, and frequently associated with a fatal outcome. Every 3 to 4 seconds somebody dies with sepsis, and it is one of the leading causes of death worldwide.
Author: The International Institute for Strategic Studies (IISS)
Publisher: Routledge
ISBN: 1000619729
Category : Political Science
Languages : en
Pages : 504
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Book Description
Published each year since 1959, The Military Balance is an indispensable reference to the capabilities of armed forces across the globe. It is used by academia, the media, armed forces, the private sector and government. It is an open-source assessment of the military forces and equipment inventories of 171 countries, with accompanying defence economics and procurement data. Alongside detailed country data, The Military Balance assesses important defence issues, by region, as well as key global trends, such as in defence technology and equipment modernisation. This analysis is accompanied by full-colour graphics, including maps and illustrations. With extensive explanatory notes and reference information, The Military Balance is as straightforward to use as it is extensive. The 2022 edition is accompanied by a fullcolour wall chart illustrating security dynamics in the Arctic.
Author: Jennifer Cearns
Publisher: UCL Press
ISBN: 1800087268
Category : Social Science
Languages : en
Pages : 294
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Book Description
Contraband Cultures presents narratives, representations, practices and imaginaries of smuggling and extra-legal or informal circulation practices, across and between the Latin American region (including the Caribbean) and its diasporas. Countering a fetishizing and hegemonic imaginary (typically stemming from the Global North) of smuggling activity in Latin America as chaotic, lawless, violent and somehow ‘exotic’, this book reframes such activities through the lenses of kinship, political movements, economic exchange and resistance to capitalist state hegemony. The volume comprises a broad range of chapters from scholars across the social sciences and humanities, using various methodological techniques, theoretical traditions and analytic approaches to explore the efficacy and valence of ‘smuggling’ or ‘contraband’ as a lens onto modes of personhood, materiality, statehood and political (dis)connection across Latin America. This material is presented through a combination of historic documentation and contemporary ethnographic research across the region to highlight the genesis and development of these cultural practices whilst grounding them in the capitalist and colonial refashioning of the entire region from the sixteenth century to the present day.
Author: Ruijie Zhang
Publisher: Frontiers Media SA
ISBN: 2832555365
Category : Science
Languages : en
Pages : 186
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Book Description
Blue foods — aquatic foods captured or farmed in marine and freshwater systems — play a key role in feeding and nourishing the world by providing highly accessible and affordable sources of protein and micronutrients for over 3.2 billion people and supporting the jobs of 58.5 million people, and the livelihoods of 600 million people. In the past 71-year period, blue foods have significantly expanded from 19.9 million tons in 1950 to 214 million tons in 2020. Yet, with 811 million people suffering from hunger and 3 billion people unable to afford a healthy diet, blue food production is poised to continue to expand in the future. However, the expansion of aquaculture and fisheries has also raised a series of ecological and environmental issues, such as biodiversity loss, environmental pollution (plastic pollution, antibiotic pollution, nitrogen and phosphorus emissions, etc.), land and freshwater use, overfishing, habitat degradation etc. In parallel, the continuously growing demand for blue food has been challenged by unprecedented environmental changes, such as climate change, ocean acidification, water pollution (microplastics, antibiotics, persistent pollutants), etc. But compared to other animal-sourced foods, blue food can remain an imperative component of sustainable food system solutions by reducing the environmental footprint and relieving pressure on overburdened terrestrial systems. Therefore, it is important to understand the challenges and priorities of the blue food transformation in order to jointly promote food safety and environmental sustainability.
Author: Tiezheng Hou
Publisher: Frontiers Media SA
ISBN: 2832552234
Category : Medical
Languages : en
Pages : 270
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Book Description
Traditionally, surgery, radiotherapy, chemotherapy and hormonal therapy have been used in clinical practice to treat cancer patients. However, these methods are either not completely tumor free or without collateral damage to health tissues. Therefore, tumor recurrence, partial remission, treatment side effect and poor tolerance in elderly patients, and lack of effective strategy to treat late-stage cancers have been the major hurdles faced by clinicians in health care. Although cancer immunotherapy including checkpoint blockade, CAR-T, oncolytic viruses, and recombinant cytokines has taken center stage in mainstream oncology because of its specifically targeting tumor cells without affecting surrounding normal cells, only a proportion of patients receiving treatment respond and others relapse after an initial response. Different tumor indications respond differently, and even in cancer types that respond, unresponsiveness are still observed. This resistance suggests that either lack of sufficient host recognition and immunity (intrinsic) or active immune suppression by tumor complex (acquired).
Author: David I. Shapiro-Ilan
Publisher: CABI
ISBN: 1800620306
Category : Science
Languages : en
Pages : 578
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Book Description
Entomopathogenic nematodes (EPNs) are biocontrol agents that are used to control a wide variety of insect pests within agriculture and forestry. In addition to their use as bio-pesticides, EPNs have a fascinating biology and are thus considered model organisms in ecology, symbiosis and pathogenesis. This book presents basic knowledge and diverse applications to illustrate how EPNs play an important role as potent biocontrol solutions. This book is a must have for all pest management professionals including those practicing integrated pest management strategies.
Author: Christoph Thiemermann
Publisher: Frontiers Media SA
ISBN: 2832556884
Category : Medical
Languages : en
Pages : 257
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Book Description
Life-threatening organ dysfunction/failure in critically ill patients suffering from sepsis or trauma is caused by a dysregulated host response to infection and/or inflammation. Despite significant advances in our understanding of some of the key signaling pathways involved in the excessive inflammation associated with sepsis/trauma, the translation of our current understanding of the underlying pathophysiology into organ-protective therapeutic strategies is still very limited. Current therapeutic approaches, hence, continue to rely on source control, antibiotics and supportive care, and particularly early goal-directed therapy.
