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Author: Carl Djerassi
Publisher:
ISBN:
Category : Biography & Autobiography
Languages : en
Pages : 240
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Book Description
Carl Djerassi, primarily known as the inventor of the birth control pill, also developed many spectroscopic techniques for structure identification, including the earliest applications of mass spectroscopy of ORD/CD to organic chemical structure. His forceful manner and inquisitive mind are reflected in his prose to make this an enjoyable and educational work.
Author: Carl Djerassi
Publisher:
ISBN:
Category : Biography & Autobiography
Languages : en
Pages : 240
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Book Description
Carl Djerassi, primarily known as the inventor of the birth control pill, also developed many spectroscopic techniques for structure identification, including the earliest applications of mass spectroscopy of ORD/CD to organic chemical structure. His forceful manner and inquisitive mind are reflected in his prose to make this an enjoyable and educational work.
Author: Mark Fainaru-Wada
Publisher: Penguin
ISBN: 110121676X
Category : Sports & Recreation
Languages : en
Pages : 535
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Book Description
In the summer of 1998 two of baseball leading sluggers, Mark McGwire and Sammy Sosa, embarked on a race to break Babe Ruth’s single season home run record. The nation was transfixed as Sosa went on to hit 66 home runs, and McGwire 70. Three years later, San Francisco Giants All-Star Barry Bonds surpassed McGwire by 3 home runs in the midst of what was perhaps the greatest offensive display in baseball history. Over the next three seasons, as Bonds regularly launched mammoth shots into the San Francisco Bay, baseball players across the country were hitting home runs at unprecedented rates. For years there had been rumors that perhaps some of these players owed their success to steroids. But crowd pleasing homers were big business, and sportswriters, fans, and officials alike simply turned a blind eye. Then, in December of 2004, after more than a year of investigation, San Francisco Chronicle reporters Mark Fainaru-Wada and Lance Williams broke the story that in a federal investigation of a nutritional supplement company called BALCO, Yankees slugger Jason Giambi had admitted taking steroids. Barry Bonds was also implicated. Immediately the issue of steroids became front page news. The revelations led to Congressional hearings on baseball’s drug problems and continued to drive the effort to purge the U.S. Olympic movement of drug cheats. Now Fainaru-Wada and Williams expose for the first time the secrets of the BALCO investigation that has turned the sports world upside down. Game of Shadows: Barry Bonds, BALCO, and the Steroid Scandal That Rocked Professional by award-winning investigative journalists Mark Fainaru-Wada and Lance Williams, is a riveting narrative about the biggest doping scandal in the history of sports, and how baseball’s home run king, Barry Bonds of the San Francisco Giants, came to use steroids. Drawing on more than two years of reporting, including interviews with hundreds of people, and exclusive access to secret grand jury testimony, confidential documents, audio recordings, and more, the authors provide, for the first time, a definitive account of the shocking steroids scandal that made headlines across the country. The book traces the career of Victor Conte, founder of the BALCO laboratory, an egomaniacal former rock musician and self-proclaimed nutritionist, who set out to corrupt sports by providing athletes with “designer” steroids that would be undetectable on “state-of-the-art” doping tests. Conte gave the undetectable drugs to 28 of the world’s greatest athletes—Olympians, NFL players and baseball stars, Bonds chief among them. A separate narrative thread details the steroids use of Bonds, an immensely talented, moody player who turned to performance-enhancing drugs after Mark McGwire of the St. Louis Cardinals set a new home run record in 1998. Through his personal trainer, Bonds gained access to BALCO drugs. All of the great athletes who visited BALCO benefited tremendously—Bonds broke McGwire’s record—but many had their careers disrupted after federal investigators raided BALCO and indicted Conte. The authors trace the course of the probe, and the baffling decision of federal prosecutors to protect the elite athletes who were involved. Highlights of Game of Shadows include: Barry Bonds A look at how Bonds was driven to use performance-enhancing drugs in part by jealousy over Mark McGwire’s record-breaking 1998 season. It was shortly thereafter that Bonds—who had never used anything more performance enhancing than a protein shake from the health food store—first began using steroids. How Bonds’s weight trainer, steroid dealer Greg Anderson, arranged to meet Victor Conte before the 2001 baseball season with...
Author: F. J. Zeelen
Publisher: Elsevier Publishing Company
ISBN:
Category : Medical
Languages : en
Pages : 380
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Book Description
The many new and fascinating data which have been gathered in the period 1985-1990 have made molecular endocrinology into a mature discipline stimulating creative chemists to design innovative drugs. Within a few years, the primary structures of all the steroid receptor proteins and most of the steroid-converting enzymes have been determined and detailed studies of their mechanism of action at a molecular level have become possible. Medicinal chemists have developed steroidal affinity probes to examine the binding sites of enzymes and receptors, and these investigations were supplemented with studies of modified enzymes and receptors prepared with the aid of site-directed mutagenesis. In view of these rapid scientific developments, the author deemed it appropriate to review the present knowledge of the medicinal chemistry of the steroids. In this book, the discussion is supported by the addition of some chapters which summarize the available data on the biological counterparts of the steroids, the steroid-converting enzymes and the steroid receptors.
Author: John D. Roberts
Publisher:
ISBN: 9780805383218
Category : Chemistry, Organic
Languages : en
Pages : 1596
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Book Description
Introduction what is organic chemistry all about?; Structural organic chemistry the shapes of molecules functional groups; Organic nomenclature; Alkanes; Stereoisomerism of organic molecules; Bonding in organic molecules atomic-orbital models; More on nomenclature compounds other than hydrocarbons; Nucleophilic substitution and elimination reactions; Separation and purification identification of organic compounds by spectroscopic techniques; Alkenes and alkynes. Ionic and radical addition reactions; Alkenes and alkynes; Oxidation and reduction reactions; Acidity or alkynes.
Author: Anthony C. Hackney
Publisher: Elsevier
ISBN: 0128134437
Category : Science
Languages : en
Pages : 169
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Book Description
Doping, Performance-Enhancing Drugs, and Hormones in Sport: Mechanisms of Action and Methods of Detection examines the biochemistry and bioanalytical aspects of performance-enhancing drugs (PEDs) and other questionable procedures used by athletes to enhance performance. The book informs the specialist of emerging knowledge and techniques and allows the non-specialist to grasp the underlying science and current practice of the discipline. With clear and compelling language appropriate for a broad spectrum of readers, this book provides background on prevalence, types of agents, their actual or supposed benefits, and their negative effects on health. The technical aspects of detection are discussed, followed by a discussion of why detection is a problematic and still-evolving science. To facilitate comprehension, each chapter is organized in a uniform way with six sections: (1) standard medical uses, (2) why the drugs are used by athletes, (3) biological mechanism of action, (4) what research says about efficacy in improving performance, (5) major health side effects from use and abuse in sport, and 6) concluding key points. - Presents the scientific concepts of how performance enhancers work, how they are used, and how they are detected and masked from detection - Features language that is neither simplistic to scientists nor too sophisticated for a large, diverse global audience - Provides a short "close-up in each chapter to illustrate key topics that engage, entertain, and create a novel synthesis of thought
Author: Rick Collins
Publisher: Legal Muscle Publishing
ISBN:
Category : Family & Relationships
Languages : en
Pages : 464
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Book Description
This book shatters the myths and misconceptions about steroid use in America. Authored by the nationally recognized legal authority on anabolics and founder of www.SteroidLaw.com, it's essential reading for natural and juiced athletes alike, and for coaches, sports trainers, physicians, journalists, and anyone in the criminal justice system. Legal Muscle is the never-before-told truth!
Author: Joe Herbert
Publisher: Oxford University Press, USA
ISBN: 0198724977
Category : Medical
Languages : en
Pages : 240
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Book Description
Testosterone lies at the heart of maleness, and is involved in aggression, competitiveness, and risk-taking -- all essential in our evolution. Joe Herbert describes the fascinating insights revealed by modern research into this primeval power that shaped our history and lurks below the veneer of our civilized modern world.
Author: Ruben Vardanyan
Publisher: Academic Press
ISBN: 0124115241
Category : Medical
Languages : en
Pages : 870
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Book Description
Synthesis of Best-Seller Drugs is a key reference guide for all those involved with the design, development, and use of the best-selling drugs. Designed for ease of use, this book provides detailed information on the most popular drugs, using a practical layout arranged according to drug type. Each chapter reviews the main drugs in each of nearly 40 key therapeutic areas, also examining their classification, novel structural features, models of action, and synthesis. Of high interest to all those who work in the captivating areas of biologically active compounds and medicinal drug synthesis, in particular medicinal chemists, biochemists, and pharmacologists, the book aims to support current research efforts, while also encouraging future developments in this important field. - Describes methods of synthesis, bioactivity and related drugs in key therapeutic areas - Reviews the main drugs in each of nearly 40 key therapeutic areas, also examining their classification, novel structural features, models of action, and more - Presents a practical layout designed for use as a quick reference tool by those working in drug design, development and implementation
Author: Jose Canseco
Publisher: Walter de Gruyter
ISBN: 9780060746407
Category : Biography & Autobiography
Languages : en
Pages : 336
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Book Description
When Jose Canseco burst into the Major Leagues in the 1980s, he changed the sport -- in more ways than one. No player before him possessed his mixture of speed and power, which allowed him to become the first man in history to belt more than forty home runs and swipe more than forty bases in the same season. He won Rookie of the Year, Most Valuable Player, and a World Series ring. Canseco shattered the mold of the out-of-shape baseball player and ushered in a new era of superathletes who looked like bodybuilders, made outrageous salaries, and enjoyed rock-star lifestyles. And the ticket for this ride? Steroids. Behind the gaudy stats and the glamour of his public life, Canseco cultivated a secret just about everyone in MLB knew about, one that would alter the game of baseball and the way we view our heroes forever. Canseco made himself a guinea pig of the performance-enhancing drugs that were only just beginning to infiltrate the American underground. Anabolic steroids, human growth hormones -- Canseco mixed, matched, and experimented to such a degree that he became known throughout the league as "The Chemist." He passed his knowledge on to trainers and fellow players, and before long, performance-enhancing drugs were running rampant throughout Major League Baseball. Sluggers scooping up pitches at their ankles and blasting them out of the park, pitchers cranking fastballs inning after inning -- Canseco showed the players how to customize their doses to sculpt the bodies they wanted, and baseball as we know it was the result. Today, this issue has crept out of the closet and burst into the headlines as players balloon to herculean proportions and hundred-year-old records are not only broken, but also demolished. In this shocking memoir, Canseco sheds light on a life of dizzying highs and debilitating lows, provides the answers to questions about steroids that millions of fans are only now beginning to ask -- and suggests that, far from being a passing trend, the steroid revolution is only a taste of things to come. Who's juiced? According to Canseco's authoritative account, more than you think. And baseball will never be the same.
Author:
Publisher: Academic Press
ISBN: 0128173173
Category : Medical
Languages : en
Pages : 290
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Book Description
Drug-Induced Liver Injury, Volume 85, the newest volume in the Advances in Pharmacology series, presents a variety of chapters from the best authors in the field. Chapters in this new release include Cell death mechanisms in DILI, Mitochondria in DILI, Primary hepatocytes and their cultures for the testing of drug-induced liver injury, MetaHeps an alternate approach to identify IDILI, Autophagy and DILI, Biomarkers and DILI, Regeneration and DILI, Drug-induced liver injury in obesity and nonalcoholic fatty liver disease, Mechanisms of Idiosyncratic Drug-Induced Liver Injury, the Evaluation and Treatment of Acetaminophen Toxicity, and much more. - Includes the authority and expertise of leading contributors in pharmacology - Presents the latest release in the Advances in Pharmacology series
