Statistical Design and Analysis of Biological Experiments PDF Download
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Author: Hans-Michael Kaltenbach
Publisher: Springer Nature
ISBN: 3030696413
Category : Mathematics
Languages : en
Pages : 281
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Book Description
This richly illustrated book provides an overview of the design and analysis of experiments with a focus on non-clinical experiments in the life sciences, including animal research. It covers the most common aspects of experimental design such as handling multiple treatment factors and improving precision. In addition, it addresses experiments with large numbers of treatment factors and response surface methods for optimizing experimental conditions or biotechnological yields. The book emphasizes the estimation of effect sizes and the principled use of statistical arguments in the broader scientific context. It gradually transitions from classical analysis of variance to modern linear mixed models, and provides detailed information on power analysis and sample size determination, including ‘portable power’ formulas for making quick approximate calculations. In turn, detailed discussions of several real-life examples illustrate the complexities and aberrations that can arise in practice. Chiefly intended for students, teachers and researchers in the fields of experimental biology and biomedicine, the book is largely self-contained and starts with the necessary background on basic statistical concepts. The underlying ideas and necessary mathematics are gradually introduced in increasingly complex variants of a single example. Hasse diagrams serve as a powerful method for visualizing and comparing experimental designs and deriving appropriate models for their analysis. Manual calculations are provided for early examples, allowing the reader to follow the analyses in detail. More complex calculations rely on the statistical software R, but are easily transferable to other software. Though there are few prerequisites for effectively using the book, previous exposure to basic statistical ideas and the software R would be advisable.
Author: Hans-Michael Kaltenbach
Publisher: Springer Nature
ISBN: 3030696413
Category : Mathematics
Languages : en
Pages : 281
Get Book Here
Book Description
This richly illustrated book provides an overview of the design and analysis of experiments with a focus on non-clinical experiments in the life sciences, including animal research. It covers the most common aspects of experimental design such as handling multiple treatment factors and improving precision. In addition, it addresses experiments with large numbers of treatment factors and response surface methods for optimizing experimental conditions or biotechnological yields. The book emphasizes the estimation of effect sizes and the principled use of statistical arguments in the broader scientific context. It gradually transitions from classical analysis of variance to modern linear mixed models, and provides detailed information on power analysis and sample size determination, including ‘portable power’ formulas for making quick approximate calculations. In turn, detailed discussions of several real-life examples illustrate the complexities and aberrations that can arise in practice. Chiefly intended for students, teachers and researchers in the fields of experimental biology and biomedicine, the book is largely self-contained and starts with the necessary background on basic statistical concepts. The underlying ideas and necessary mathematics are gradually introduced in increasingly complex variants of a single example. Hasse diagrams serve as a powerful method for visualizing and comparing experimental designs and deriving appropriate models for their analysis. Manual calculations are provided for early examples, allowing the reader to follow the analyses in detail. More complex calculations rely on the statistical software R, but are easily transferable to other software. Though there are few prerequisites for effectively using the book, previous exposure to basic statistical ideas and the software R would be advisable.
Author: Angela Dean
Publisher: CRC Press
ISBN: 146650434X
Category : Mathematics
Languages : en
Pages : 946
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Book Description
This carefully edited collection synthesizes the state of the art in the theory and applications of designed experiments and their analyses. It provides a detailed overview of the tools required for the optimal design of experiments and their analyses. The handbook covers many recent advances in the field, including designs for nonlinear models and algorithms applicable to a wide variety of design problems. It also explores the extensive use of experimental designs in marketing, the pharmaceutical industry, engineering and other areas.
Author: Ghosh
Publisher: CRC Press
ISBN: 9780824782511
Category : Mathematics
Languages : en
Pages : 562
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Book Description
Author: John Lawson
Publisher: CRC Press
ISBN: 1498728480
Category : Mathematics
Languages : en
Pages : 629
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Book Description
Design and Analysis of Experiments with R presents a unified treatment of experimental designs and design concepts commonly used in practice. It connects the objectives of research to the type of experimental design required, describes the process of creating the design and collecting the data, shows how to perform the proper analysis of the data,
Author: Charles Lipson
Publisher: McGraw-Hill Companies
ISBN:
Category : Science
Languages : en
Pages : 546
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Book Description
Author: Klaus Hinkelmann
Publisher: John Wiley & Sons
ISBN: 9780471551782
Category : Mathematics
Languages : en
Pages : 528
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Book Description
Design and analysis of experiments/Hinkelmann.-v.1.
Author: Ajit C. Tamhane
Publisher: John Wiley & Sons
ISBN: 1118491432
Category : Science
Languages : en
Pages : 724
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Book Description
A indispensable guide to understanding and designing modern experiments The tools and techniques of Design of Experiments (DOE) allow researchers to successfully collect, analyze, and interpret data across a wide array of disciplines. Statistical Analysis of Designed Experiments provides a modern and balanced treatment of DOE methodology with thorough coverage of the underlying theory and standard designs of experiments, guiding the reader through applications to research in various fields such as engineering, medicine, business, and the social sciences. The book supplies a foundation for the subject, beginning with basic concepts of DOE and a review of elementary normal theory statistical methods. Subsequent chapters present a uniform, model-based approach to DOE. Each design is presented in a comprehensive format and is accompanied by a motivating example, discussion of the applicability of the design, and a model for its analysis using statistical methods such as graphical plots, analysis of variance (ANOVA), confidence intervals, and hypothesis tests. Numerous theoretical and applied exercises are provided in each chapter, and answers to selected exercises are included at the end of the book. An appendix features three case studies that illustrate the challenges often encountered in real-world experiments, such as randomization, unbalanced data, and outliers. Minitab® software is used to perform analyses throughout the book, and an accompanying FTP site houses additional exercises and data sets. With its breadth of real-world examples and accessible treatment of both theory and applications, Statistical Analysis of Designed Experiments is a valuable book for experimental design courses at the upper-undergraduate and graduate levels. It is also an indispensable reference for practicing statisticians, engineers, and scientists who would like to further their knowledge of DOE.
Author: Peter W. M. John
Publisher: SIAM
ISBN: 0898714273
Category : Mathematics
Languages : en
Pages : 378
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Book Description
An invaluable reference on the design of experiments. Includes hard-to-find information on change-over designs and analysis of covariance.
Author: Douglas C. Montgomery
Publisher: Wiley
ISBN: 9780471661597
Category : Experimental design
Languages : en
Pages : 0
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Book Description
This bestselling professional reference has helped over 100,000 engineers and scientists with the success of their experiments. The new edition includes more software examples taken from the three most dominant programs in the field: Minitab, JMP, and SAS. Additional material has also been added in several chapters, including new developments in robust design and factorial designs. New examples and exercises are also presented to illustrate the use of designed experiments in service and transactional organizations. Engineers will be able to apply this information to improve the quality and efficiency of working systems.
Author: Helge Toutenburg
Publisher: Springer Science & Business Media
ISBN: 0387227725
Category : Mathematics
Languages : en
Pages : 507
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Book Description
Unique in commencing with relatively simple statistical concepts and ideas found in most introductory statistical textbooks, this book goes on to cover more material useful for undergraduates and graduate in statistics and biostatistics.
