Ultra-Low Field Nuclear Magnetic Resonance

Ultra-Low Field Nuclear Magnetic Resonance PDF Author: Robert Kraus Jr.
Publisher: Oxford University Press
ISBN: 0199796513
Category : Medical
Languages : en
Pages : 266

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Book Description
This book is designed to introduce the reader to the field of NMR/MRI at very low magnetic fields, from milli-Tesla to micro-Tesla, the ultra-low field (ULF) regime. The book is focused on applications to imaging the human brain, and hardware methods primarily based upon pre-polarization methods and SQUID-based detection. The goal of the text is to provide insight and tools for the reader to better understand what applications are best served by ULF NMR/MRI approaches. A discussion of the hardware challenges, such as shielding, operation of SQUID sensors in a dynamic field environment, and pulsed magnetic field generation are presented. One goal of the text is to provide the reader a framework of understanding the approaches to estimation and mitigation of low signal-to-noise and long imaging time, which are the main challenges. Special attention is paid to the combination of MEG and ULF MRI, and the benefits and challenges presented by trying to accomplish both with the same hardware. The book discusses the origin of unique relaxation contrast at ULF, and special considerations for image artifacts and how to correct them (i.e. concomitant gradients, ghost artifacts). A general discussion of MRI, with special consideration to the challenges of imaging at ULF and unique opportunities in pulse sequences, is presented. The book also presents an overview of some of the primary applications of ULF NMR/MRI being pursued.

Ultra-Low Field Nuclear Magnetic Resonance

Ultra-Low Field Nuclear Magnetic Resonance PDF Author: Robert Kraus Jr.
Publisher: Oxford University Press
ISBN: 0199796513
Category : Medical
Languages : en
Pages : 266

Get Book Here

Book Description
This book is designed to introduce the reader to the field of NMR/MRI at very low magnetic fields, from milli-Tesla to micro-Tesla, the ultra-low field (ULF) regime. The book is focused on applications to imaging the human brain, and hardware methods primarily based upon pre-polarization methods and SQUID-based detection. The goal of the text is to provide insight and tools for the reader to better understand what applications are best served by ULF NMR/MRI approaches. A discussion of the hardware challenges, such as shielding, operation of SQUID sensors in a dynamic field environment, and pulsed magnetic field generation are presented. One goal of the text is to provide the reader a framework of understanding the approaches to estimation and mitigation of low signal-to-noise and long imaging time, which are the main challenges. Special attention is paid to the combination of MEG and ULF MRI, and the benefits and challenges presented by trying to accomplish both with the same hardware. The book discusses the origin of unique relaxation contrast at ULF, and special considerations for image artifacts and how to correct them (i.e. concomitant gradients, ghost artifacts). A general discussion of MRI, with special consideration to the challenges of imaging at ULF and unique opportunities in pulse sequences, is presented. The book also presents an overview of some of the primary applications of ULF NMR/MRI being pursued.

Ultra-Low Field Nuclear Magnetic Resonance

Ultra-Low Field Nuclear Magnetic Resonance PDF Author: Robert Kraus Jr.
Publisher: Oxford University Press
ISBN: 0199347883
Category : Medical
Languages : en
Pages : 266

Get Book Here

Book Description
This book is designed to introduce the reader to the field of NMR/MRI at very low magnetic fields, from milli-Tesla to micro-Tesla, the ultra-low field (ULF) regime. The book is focused on applications to imaging the human brain, and hardware methods primarily based upon pre-polarization methods and SQUID-based detection. The goal of the text is to provide insight and tools for the reader to better understand what applications are best served by ULF NMR/MRI approaches. A discussion of the hardware challenges, such as shielding, operation of SQUID sensors in a dynamic field environment, and pulsed magnetic field generation are presented. One goal of the text is to provide the reader a framework of understanding the approaches to estimation and mitigation of low signal-to-noise and long imaging time, which are the main challenges. Special attention is paid to the combination of MEG and ULF MRI, and the benefits and challenges presented by trying to accomplish both with the same hardware. The book discusses the origin of unique relaxation contrast at ULF, and special considerations for image artifacts and how to correct them (i.e. concomitant gradients, ghost artifacts). A general discussion of MRI, with special consideration to the challenges of imaging at ULF and unique opportunities in pulse sequences, is presented. The book also presents an overview of some of the primary applications of ULF NMR/MRI being pursued.

High-Tc SQUIDs for Biomedical Applications: Immunoassays, Magnetoencephalography, and Ultra-Low Field Magnetic Resonance Imaging

High-Tc SQUIDs for Biomedical Applications: Immunoassays, Magnetoencephalography, and Ultra-Low Field Magnetic Resonance Imaging PDF Author: Fredrik Öisjöen
Publisher: Springer Science & Business Media
ISBN: 3642313566
Category : Technology & Engineering
Languages : en
Pages : 111

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Book Description
This thesis describes the challenging task of developing high critical temperature superconducting quantum interference devices (high-Tc SQUIDs) and using them as sensors for biomedical applications, including magnetic immunoassays, magnetoencephalography and magnetic resonance imaging (MRI). The first part of this work discusses the development of fast magnetic immunoassays, which can be used to improve the sensitivity, or to create new, unique point-of-care diagnostics systems. The second part shows that high-Tc SQUIDs might make magnetoencephalography more available, thus opening the field of high-Tc SQUID-based magnetoencephalography for recording brain functions. This technique can be combined with ultra-low field MRI which is discussed in the last part. This combination may provide a new unique tool for studies of brain functions. This work does not simply improve on existing technology but opens possibilities for novel advanced medical devices and techniques.

SQUID-detected NMR and MRI in Microtesla Magnetic Fields

SQUID-detected NMR and MRI in Microtesla Magnetic Fields PDF Author: Robert Francis McDermott
Publisher:
ISBN:
Category :
Languages : en
Pages : 310

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Book Description


Nanomagnetism

Nanomagnetism PDF Author: Claude Fermon
Publisher: John Wiley & Sons
ISBN: 3527699066
Category : Science
Languages : en
Pages : 376

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Book Description
This first book to focus on the applications of nanomagnetism presents those already realized while also suggesting bold ideas for further breakthroughs. The first part is devoted to the concept of spin electronics and its use for data storage and magnetic sensing, while the second part concentrates on magnetic nanoparticles and their use in industrial environment, biological and medical applications. The third, more prospective part goes on to describe emerging applications related to spin current creation and manipulation, dynamics, spin waves and binary logic based on nano-scale magnetism. With its unique choice of topics and authors, this will appeal to academic as well as corporate researchers in a wide range of disciplines from physics via materials science to engineering, chemistry and life science.

17th International Conference on Biomagnetism Advances in Biomagnetism - Biomag 2010 - March 28 - April 1, 2010

17th International Conference on Biomagnetism Advances in Biomagnetism - Biomag 2010 - March 28 - April 1, 2010 PDF Author: Selma Supek
Publisher: Springer Science & Business Media
ISBN: 3642121977
Category : Technology & Engineering
Languages : en
Pages : 475

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Book Description
40th anniversary of "medical uses of SQUID" th It is my great pleasure and honor to invite you to the 17 International Conference on Biomagnetism – Biomag2010 held in Dubrovnik, Croatia from Sunday, March 28 through Thursday, April 1, 2010. The interdisciplinary field of biomagnetism includes dynamic and evolving SQUID-based technologies offering advanced real-time methods for noninvasive assessments of magnetic signals from the brain, heart and other organs as well as a range of modeling, mathematical and computational methods for functional source localization approaches. Excellent spatial resolution and unique, millisecond, temporal resolution of biomagnetic techniques allow insights into cortical neurodynamics and neurobiological basis of the human brain as well as assessment of heart and other organs functions in health and disease. Biomag2010 will be a great opportunity for an exchange of ideas and presentation of the latest developments in instrumentation, modeling approaches, basic and clinical biomedical studies. We are particularly proud to announce the celebration of the 40th anniversary of the first SQUID-based MCG measurements published on April 1, 1970. Since then ''medical uses of SQUID'' were dynamic and growing, including the most recent developments, in combination with a low field MRI, toward a ''direct neuronal imaging''. Dubrovnik, the host city of the Biomag2010, a jewel on the Adriatic, will be a superb and stimulating setting for both scientific and social aspects of this meeting. I am looking forward to hosting you in Dubrovnik, Croatia in spring of 2010.

Magnetoencephalography

Magnetoencephalography PDF Author: Selma Supek
Publisher: Springer
ISBN: 3642330452
Category : Technology & Engineering
Languages : en
Pages : 999

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Book Description
Magnetoencephalography (MEG) is an invaluable functional brain imaging technique that provides direct, real-time monitoring of neuronal activity necessary for gaining insight into dynamic cortical networks. Our intentions with this book are to cover the richness and transdisciplinary nature of the MEG field, make it more accessible to newcomers and experienced researchers and to stimulate growth in the MEG area. The book presents a comprehensive overview of MEG basics and the latest developments in methodological, empirical and clinical research, directed toward master and doctoral students, as well as researchers. There are three levels of contributions: 1) tutorials on instrumentation, measurements, modeling, and experimental design; 2) topical reviews providing extensive coverage of relevant research topics; and 3) short contributions on open, challenging issues, future developments and novel applications. The topics range from neuromagnetic measurements, signal processing and source localization techniques to dynamic functional networks underlying perception and cognition in both health and disease. Topical reviews cover, among others: development on SQUID-based and novel sensors, multi-modal integration (low field MRI and MEG; EEG and fMRI), Bayesian approaches to multi-modal integration, direct neuronal imaging, novel noise reduction methods, source-space functional analysis, decoding of brain states, dynamic brain connectivity, sensory-motor integration, MEG studies on perception and cognition, thalamocortical oscillations, fetal and neonatal MEG, pediatric MEG studies, cognitive development, clinical applications of MEG in epilepsy, pre-surgical mapping, stroke, schizophrenia, stuttering, traumatic brain injury, post-traumatic stress disorder, depression, autism, aging and neurodegeneration, MEG applications in cognitive neuropharmacology and an overview of the major open-source analysis tools.

Label-Free Biosensing

Label-Free Biosensing PDF Author: Michael J. Schöning
Publisher: Springer
ISBN: 3319752200
Category : Science
Languages : en
Pages : 485

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Book Description
This volume summarizes the state-of-the-art technologies, key advances and future trends in the field of label-free biosensing. It provides detailed insights into the different types of solid-state, label-free biosensors, their underlying transducer principles, advanced materials utilized, device-fabrication techniques and various applications. The book offers graduate students, academic researchers, and industry professionals a comprehensive source of information on all facets of label-free biosensing and the future trends in this flourishing field. Highlights of the subjects covered include label-free biosensing with: · semiconductor field-effect devices such as nanomaterial-modified capacitive electrolyte-insulator-semiconductor structures, silicon nanowire transistors, III-nitride semiconductor devices and light-addressable potentiometric sensors · impedimetric biosensors using planar and 3D electrodes · nanocavity and solid-state nanopore devices · carbon nanotube and graphene/graphene oxide biosensors · electrochemical biosensors using molecularly imprinted polymers · biomimetic sensors based on acoustic signal transduction · enzyme logic systems and digital biosensors based on the biocomputing concept · heat-transfer as a novel transducer principle · ultrasensitive surface plasmon resonance biosensors · magnetic biosensors and magnetic imaging devices

Applied Superconductivity

Applied Superconductivity PDF Author: Paul Seidel
Publisher: John Wiley & Sons
ISBN: 3527412093
Category : Technology & Engineering
Languages : en
Pages : 1334

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Book Description
This wide-ranging presentation of applied superconductivity, from fundamentals and materials right up to the details of many applications, is an essential reference for physicists and engineers in academic research as well as in industry. Readers looking for a comprehensive overview on basic effects related to superconductivity and superconducting materials will expand their knowledge and understanding of both low and high Tc superconductors with respect to their application. Technology, preparation and characterization are covered for bulk, single crystals, thins fi lms as well as electronic devices, wires and tapes. The main benefit of this work lies in its broad coverage of significant applications in magnets, power engineering, electronics, sensors and quantum metrology. The reader will find information on superconducting magnets for diverse applications like particle physics, fusion research, medicine, and biomagnetism as well as materials processing. SQUIDs and their usage in medicine or geophysics are thoroughly covered, as are superconducting radiation and particle detectors, aspects on superconductor digital electronics, leading readers to quantum computing and new devices.

Mobile NMR and MRI

Mobile NMR and MRI PDF Author: Mike Johns
Publisher: Royal Society of Chemistry
ISBN: 1849739153
Category : Medical
Languages : en
Pages : 364

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Book Description
This book will summarise recent hardware developments, highlight the challenges facing mobile and generally low-field NMR and MRI and describe various emerging applications - some of which have commercial interest.