Some Pyrazolines Derived by Benzimidazolyl Chalcones PDF Download
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Author: Jayanti S. Rajora
Publisher: LAP Lambert Academic Publishing
ISBN: 9783659624315
Category :
Languages : en
Pages : 96
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Book Description
This book provides a brief knowledge about synthesis and medicinal importance of benzimidazolyl derivatives and pyrazolines. Chapter one of this book incorporates introduction and importance of benzimidazolyl chalcones and pyrazolines. Chapter two includes account on synthesis of pyrazoline using microwave-assisted and conventional methods. Synthesis of 3-benzimidazolyl-5-aryl-2-pyrazoline-1-carboxaldehydes and characterization of synthesized compounds is given in chapter three. Chapter four deal with biological activities of benzimidazolyl derivatives. Chapter five includes study of antimicrobial (antibacterial and antifungal) activities of 3-benzimidazolyl-5-aryl-2- pyrazoline-1-carboxaldehydes.
Author: Jayanti S. Rajora
Publisher: LAP Lambert Academic Publishing
ISBN: 9783659624315
Category :
Languages : en
Pages : 96
Get Book Here
Book Description
This book provides a brief knowledge about synthesis and medicinal importance of benzimidazolyl derivatives and pyrazolines. Chapter one of this book incorporates introduction and importance of benzimidazolyl chalcones and pyrazolines. Chapter two includes account on synthesis of pyrazoline using microwave-assisted and conventional methods. Synthesis of 3-benzimidazolyl-5-aryl-2-pyrazoline-1-carboxaldehydes and characterization of synthesized compounds is given in chapter three. Chapter four deal with biological activities of benzimidazolyl derivatives. Chapter five includes study of antimicrobial (antibacterial and antifungal) activities of 3-benzimidazolyl-5-aryl-2- pyrazoline-1-carboxaldehydes.
Author: Maria Marinescu
Publisher: BoD – Books on Demand
ISBN: 1789845521
Category : Science
Languages : en
Pages : 230
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Book Description
Finding new strategies for synthesizing benzimidazole derivatives and functionalizing the benzimidazole core has proved to be important due to the compound's various applications in medicine, chemistry, and other areas. The multitude of benzimidazole derivatives marketed as drugs has led to intensive research in the field for the discovery of new biologically active structures. The general applications of benzimidazole derivatives in materials chemistry, electronics, technology, dyes, pigments, and agriculture open up new research horizons. This book guides the rational design of benzimidazole derivatives synthesis with certain applications. Chapters cover such topics as therapeutic use of benzimidazole in conditions like diabetes, viruses, and parasitic diseases; X-ray crystal structure of selected benzimidazole derivatives; benzimidazole compounds for cancer therapy; and others.
Author: Jacques V. Metzger
Publisher:
ISBN:
Category : Thiazoles
Languages : en
Pages : 440
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Book Description
Author: Astrid Sigel
Publisher: John Wiley & Sons
ISBN: 0470028122
Category : Science
Languages : en
Pages : 728
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Book Description
Helmut Sigel, Astrid Sigel and Roland K.O. Sigel, in close cooperation with John Wiley & Sons, launch a new Series “Metal Ions in Life Sciences”. The philosophy of the Series is based on the one successfully applied to a previous series published by another publisher, but the move from “biological systems” to “life sciences” will open the aims and scope and allow for the publication of books touching on the interface between chemistry, biology, pharmacology, biochemistry and medicine. Volume 2 focuses on the vibrant research area concerning nickel as well as its complexes and their role in Nature. With more than 2,800 references and over 130 illustrations, it is an essential resource for scientists working in the wide range from inorganic biochemistry all the way through to medicine. In 17 stimulating chapters, written by 47 internationally recognized experts, Nickel and Its Surprising Impact in Nature highlights critically the biogeochemistry of nickel, its role in the environment, in plants and cyanobacteria, as well as for the gastric pathogen Helicobacter pylori, for gene expression and carcinogenensis. In addition, it covers the complex-forming properties of nickel with amino acids, peptides, phosphates, nucleotides, and nucleic acids. The volume also provides sophisticated insights in the recent progress made in understanding the role of nickel in enzymes such as ureases, hydrogenases, superoxide dismutases, acireductone dioxygenases, acetyl-coenzyme A synthases, carbon monoxide dehydrogenases, methyl-coenzyme M reductases...and it reveals the chaperones of nickel metabolism.
Author: Vakhid A. Mamedov
Publisher: Springer
ISBN: 3319297732
Category : Science
Languages : en
Pages : 451
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Book Description
This book reviews the fundamental aspects of quinoxaline chemistry: synthesis, reactions, mechanisms, structure, properties, and uses. The first four chapters present a survey of the developments in quinoxaline chemistry since the publication of the monograph on “Condensed Pyrazines” by Cheeseman and Cookson in 1979. These chapters give comprehensive coverage of all the methods of the synthesis of quinoxalines and the important quinoxaline-containing ring systems such as thiazolo[3,4-a]-, pyrrolo[1,2-a]-, and imidazo[1,5-a]quinoxalines. Chapter five describes many new methods for the construction of quinoxaline macrocycles, which are important in applications such as optical devices and materials. The final chapter reviews all previously known rearrangements of heterocyclic systems that lead to benzimidazole derivatives. Mamedov critically analyses these transformations to reveal a novel acid-catalyzed rearrangement of quinoxalinones giving 2-heteroarylbenzimidazoles and 1-heteroarylbenzimidazolones in the presence of nucleophilic reactants (MAMEDOV Heterocycle Rearrangement). This book is of interest to researchers in the fields of heterocyclic and synthetic organic chemistry.
Author: François Jérôme
Publisher: John Wiley & Sons
ISBN: 1119065445
Category : Science
Languages : en
Pages : 183
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Book Description
A multidisciplinary overview of bio-derived solvent applications, life cycle analysis, and strategies required for industrial commercialization This book provides the first and only comprehensive review of the state-of-the-science in bio-derived solvents. Drawing on their own pioneering work in the field, as well as an exhaustive survey of the world literature on the subject, the authors cover all the bases—from bio-derived solvent applications to life cycle analysis to strategies for industrial commercialization—for researchers and professional chemists working across a range of industries. In the increasingly critical area of sustainable chemistry, the search for new and better green solvents has become a top priority. Thanks to their renewability, biodegradability and low toxicity, as well as their potential to promote advantageous organic reactions, green solvents offer the promise of significantly reducing the pernicious effects of chemical processes on human health and the environment. Following an overview of the current solvents markets and the challenges and opportunities presented by bio-derived solvents, a series of dedicated chapters cover all significant classes of solvent arranged by origin and/or chemical structure. Throughout, real-world examples are used to help demonstrate the various advantages, drawbacks, and limitations of each class of solvent. Topics covered include: The commercial potential of various renewably sourced solvents, such as glycerol The various advantages and disadvantages of bio-derived versus petroleum-based solvents Renewably-sourced and waste-derived solvents in the design of eco-efficient processes Life cycle assessment and predictive methods for bio-based solvents Industrial and commercial viability of bio-based solvents now and in the years ahead Potential and limitations of methodologies involving bio-derived solvents New developments and emerging trends in the field and the shape of things to come Considering the vast potential for new and better products suggested by recent developments in this exciting field, Bio-Based Solvents will be a welcome resource among students and researchers in catalysis, organic synthesis, electrochemistry, and pharmaceuticals, as well as industrial chemists involved in manufacturing processes and formulation, and policy makers.
Author: Thomas Lion
Publisher: Humana
ISBN: 9781493965137
Category : Science
Languages : en
Pages : 0
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Book Description
This detailed volume presents timely and authoritative content offering a comprehensive overview of the current state of the art in fungal diagnostics. Moreover, it addresses on-going developments expected to provide a basis for targeted treatment strategies resulting in improved outcome of invasive mycoses. The knowledge of host-related predisposing factors and stratified treatment options facilitating timely onset of adequate antifungal therapy are critical for successful clinical management and outcome of invasive fungal disease (IFD), requiring not only rapid diagnosis of a fungal infection and identification of the causative species, but also assessment of pathogen/host factors related to pathogenicity, susceptibility, and response to treatment. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Human Fungal Pathogen Identification: Methods and Protocols serves as an ideal reference for researchers investigating the ever-growing worldwide healthcare problems involving fungal infections.
Author: Jeffrey B. Harborne
Publisher: Springer
ISBN: 1489929096
Category : Science
Languages : en
Pages : 1218
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Book Description
The flavonoids, one of the most numerous and widespread groups of natural constituents, are important to man not only because they contribute to plant colour but also because many members (e.g. coumestrol, phloridzin, rotenone) are physiologically active. Nearly two thousand substances have been described and as a group they are universally distributed among vascular plants. Although the anthocyanins have an undisputed function as plant pigments, the raison d'etre for the more widely distributed colourless flavones and flavonols still remains a mystery. It is perhaps the challenge of discovering these yet undisc10sed functions which has caused the considerable resurgence of interest in flavonoids during the last decade. This book attempts to summarize progress that has been made in the study of these constituents since the first comprehensive monograph on the chemistry of the flavonoid compounds was published, under the editorship of T. A. Geissman, in 1962. The present volume is divided into three parts. The first section (Chapters 1-4) deals with advances in chemistry, the main emphasis being on spectral techniques to take into account the re cent successful applications of NMR and mass spectral measurements to structural identifications. Recent developments in isolation techniques and in synthesis are also covered in this section. Advances in chemical knowledge of individual c1asses of flavonoid are mentioned inter aha in later chapters of the book.
Author:
Publisher:
ISBN:
Category : Science
Languages : en
Pages : 1106
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Book Description
Author: Ananya Srivastava
Publisher:
ISBN: 9789811391453
Category : Heterocyclic chemistry
Languages : en
Pages : 498
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Book Description
This book discusses the developments in the synthesis and functionalization of different heterocycles based on the formation of carbon-carbon (C-C) and carbon-heteroatom (C-X) bonds using cross-dehydrogenative coupling (CDC). Consisting of 13 chapters, the book systematically describes the advances in the synthesis and functionalization of nitrogen, oxygen, and sulfur-containing heterocycles. It also discusses the various mechanistic pathways to help readers gain an in-depth understanding of the CDC reactions of heterocycles. Lastly, in order to promote green chemistry, it addresses a range of metal-free CDC reactions of heterocycles - an area that has attracted significant attention in both academic and industrial research.
